How to treat Prostate cancer?

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¿Kunjamsa próstata usut qollañasa?

Akax kunayman qullirinakaruw yanapt'i, kunjamati aka usux uñsti, kunjam ch'amanisa, usutan k'umar jakäwipa, kunjams qullirinakax munapxi ukanakxata.

Yaqhip tratamientos ukanakax akanakawa:

1. Uñch'ukiña: Aka uñanchawix cancer ukarux jak'at uñch'ukiña, uñakipt'aña ukhamarak yant'aña, janiw jank'ak qullayasiñ qalltañakiti.

Ukaxa, jan walinakar jan puriyir próstata cancer usun chachanakaruw yanapt'aspa.

2. Cirugía: Prostatitis ukan janchip apaqasiñataki.

Ukax cirugía abierta jan ukax laparoscópica (jisk'a jisk'a chhuxrinakamp ukat herramientas especializadas) ukamp lurasispawa.

3. Radioterapia: akax radiación de alta energía ukampiw cancer ukan celulanakaparux jiwayata.

Inas mä maquinampi janchit apsutächi, jan ukajj tumor jakʼar uchatächi.

4. Hormona terapia: Aka terapiajj hormona masculino (andrógenos) ukanakan pisïtapwa amuyayi, ukaw próstata cancer usur saykatañatakisa, jan ukajj jukʼat jukʼat jiltañapatakis yanaptʼaspa.

Ukaxa sapaki jan ukax yaqha qullanakampi chikaw apnaqasispa.

5. Quimioterapia: akax cáncer ukan ch'uxñatatir celulas ukanakaruw jiwayir usu.

Ukaxa, próstata cancer usutakix wali askiwa, yaqha chiqanakar saratatata.

6. Inmunoterapia: akax sistema inmunológico ukaruw cancer ukamp nuwasïwir yanapt'i.

Ukaxa, cáncer de próstata avanzado ukatakix apnaqataspawa, yaqha qullirinakax janiw yanapt'kiti.

7. terapia dirigida: aka terapiax genes específicos jan ukax proteínas ukanakaruw yanpt'i, ukanakaw células cancerosas ukanakar jiltayapxañapataki ukhamarak jakapxañapatak yanapt'i.

Ukaxa, cáncer de próstata avanzado ukatakix apnaqataspawa, yaqha qullirinakax janiw yanapt'kiti.

8. Crioterapia: aka qullaw cancer celulanakar wali thayanakar tukuyañataki ukhamarak jiwarayañataki.

Uka usuxa, nayrïr kuti uñstki uka cáncer de próstata jan ukax yaqha usunakat kutt'anir cancer ukanakatakis apnaqarakispawa.

9.- Ultrasonido enfocado de alta intensidad (HIFU): Aka qullaw cancer ukatak células cancerosas ukar nakhantañataki ukhamarak tukjañataki ondas de sonido de alta frecuencia ukanak apnaqasi.

Uka usuxa, nayrïr kuti uñstki uka cáncer de próstata jan ukax yaqha usunakat kutt'anir cancer ukanakatakis apnaqarakispawa.

10. Uñch'ukiña: Aka uñanchawix cancer ukarux sum uñch'ukiña, sapa kuti uñakipt'aña ukhamarak yant'aña, ukampirus janiw qullayasiñx qalltañakiti, janitix sintomanakas uñstani jan ukax mayjt'kani ukjaxa.

Inas jilïr chachanakaru, cáncer de próstata usuninakarusa, jan ukajj yaqha usutanakarusa yanaptʼchispa.

Wali wakiskiriwa qullañ qutucht'at aruskipaña taqi usutanakar qullañataki, ukhamat sapa usutakisa askïni.

['Qillqatanaka']

PubMed/Medline https://www.nlm.nih.gov/databases/download/pubmed_medline.html

RefinedWeb https://arxiv.org/abs/2306.01116

Wang Y, Chen J, Wu Z, Ding W, Gao S, Gao Y, Xu C: Mechanisms of enzalutamide resistance in castration-resistant prostate cancer and therapeutic strategies to overcome it. Br J Pharmacol. 2021, 178 (2): 239-261.

Talkar SS, Patravale VB: Gene Therapy for Prostate Cancer: A Review. Endocr Metab Immune Disord Drug Targets. 2021, 21 (3): 385-396.

Šamija I, Fröbe A: CHALLENGES IN MANIPULATING IMMUNE SYSTEM TO TREAT PROSTATE CANCER. Acta Clin Croat. 2019, 58 (Suppl 2): 76-81.

Akaza H, Hinotsu S, Usami M, Ogawa O, Kagawa S, Kitamura T, Tsukamoto T, Naito S, Hirao Y, Murai M, Yamanaka H, Namiki M: The case for androgen deprivation as primary therapy for early stage disease: results from J-CaP and CaPSURE. J Urol. 2006, 176 (6 Pt 2): S47-9.

Abraham-Miranda J, Awasthi S, Yamoah K: Immunologic disparities in prostate cancer between American men of African and European descent. Crit Rev Oncol Hematol. 2021, 164 (): 103426.

de Vrij J, Willemsen RA, Lindholm L, Hoeben RC, Bangma CH, Barber C, Behr JP, Briggs S, Carlisle R, Cheng WS, Dautzenberg IJ, de Ridder C, Dzojic H, Erbacher P, Essand M, Fisher K, Frazier A, Georgopoulos LJ, Jennings I, Kochanek S, Koppers-Lalic D, Kraaij R, Kreppel F, Magnusson M, Maitland N, Neuberg P, Nugent R, Ogris M, Remy JS, Scaife M, Schenk-Braat E, Schooten E, Seymour L, Slade M, Szyjanowicz P, Totterman T, Uil TG, Ulbrich K, van der Weel L, van Weerden W, Wagner E, Zuber G: Adenovirus-derived vectors for prostate cancer gene therapy. Hum Gene Ther. 2010, 21 (7): 795-805.

Lee E, Ha S, Logan SK: Divergent Androgen Receptor and Beta-Catenin Signaling in Prostate Cancer Cells. PLoS One. 2015, 10 (10): e0141589.

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How to treat prostate cancer?

There are several treatment options available for prostate cancer, depending on the stage and aggressiveness of the cancer, as well as the patient's overall health and personal preferences.

Some common treatments include:

1. Active surveillance: This approach involves closely monitoring the cancer with regular checkups and tests, rather than immediately starting treatment.

It may be suitable for men with low-risk prostate cancer.

2. Surgery: A prostatectomy is a surgical procedure to remove the prostate gland.

It can be done through open surgery or laparoscopically (using small incisions and specialized tools).

3. Radiation therapy: This treatment uses high-energy radiation to kill cancer cells.

It can be delivered externally (from a machine outside the body) or internally (through implants placed near the tumor).

4. Hormone therapy: This treatment reduces the levels of male hormones (androgens) in the body, which can slow or stop the growth of prostate cancer.

It can be used alone or in combination with other treatments.

5. Chemotherapy: This treatment uses drugs to kill cancer cells.

It may be used for advanced prostate cancer that has spread to other parts of the body.

6. Immunotherapy: This treatment helps the immune system fight cancer.

It may be used for advanced prostate cancer that has not responded to other treatments.

7. Targeted therapy: This treatment targets specific genes or proteins that help cancer cells grow and survive.

It may be used for advanced prostate cancer that has not responded to other treatments.

8. Cryotherapy: This treatment uses extreme cold to freeze and kill cancer cells.

It may be used for early-stage prostate cancer or for cancer that has come back after other treatments.

9. High-intensity focused ultrasound (HIFU): This treatment uses high-frequency sound waves to heat and destroy cancer cells.

It may be used for early-stage prostate cancer or for cancer that has come back after other treatments.

10. Watchful waiting: This approach involves closely monitoring the cancer with regular checkups and tests, but not starting treatment unless symptoms appear or change.

It may be suitable for older men with slow-growing prostate cancer and other serious health conditions.

It is important to discuss all treatment options with a healthcare team to determine the best course of action for each individual case.

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