What causes Prostate cancer?

['Engkalingai iyaé bagiyangngé']

Aga nassabari kanker prostat?

Saba' mattentu kanker prostat de'na riisseng, naekiya siare faktor pura riidentifikasi iya nulle napamenceng resiko nakenna lasa e.

Iyyae muttama:

1. Umuru: Ancamang kanker prostat tattambai nasibawai umuru, sibawa macahoro kasus kajajiang ri urane lebbi pole 65 taung.

2. Sejarah keluarga: Tauwe sibawa sejarah keluarga kanker prostat, utamana ambo' iyarega silessureng napunnai lasa e, engka ri resiko lebbi matanre.

3. Ras: Tau Afrika Amerika punnai resiko lebbi matanre nakenna kanker prostat naiyya tau pole ras lainge.

4. Anre'na: Anre' iya maega gemme'na, utamana gemme' olokolo, nulle napenrei resiko kanker prostat.

5. Obesitas: Mabbanni iyarega lebbie naulle napatanrei resiko nakenna kanker prostat.

6. Hormon: Tingka' testosteron iya matanre nenniya hormon worowané laingnge nulle napatanrei resiko kanker prostat.

7. Peradangan: Peradangan prostat kronik, pada padanna prostatitis, nulle napatanrei resiko kanker prostat.

8. Genetika: Mutasi genetik tertentu iya riruntu'e, pappada iya engkae ri gen BRCA1 nenniya BRCA2, nulle napamenceng resiko kanker prostat.

Parellu riisseng majeppu punnai seddi iyarega lebbi pole ri faktor resiko e ro de'na bettuangi majeppu seddi tau e pasti nakennai kanker prostat, nenniya maega tau sibawa kanker prostat de'na punnai faktor resiko iya riissenge.

Rilainnaero, apparessang mattengngang ripigau untu' napahang lebbi makessing passabarenna kanker prostat nenniya untu' pattentui faktor resiko tambahan.

['Rilaleng']

PubMed/Medline https://www.nlm.nih.gov/databases/download/pubmed_medline.html

RefinedWeb https://arxiv.org/abs/2306.01116

Riihimäki M, Thomsen H, Brandt A, Sundquist J, Hemminki K: What do prostate cancer patients die of? Oncologist. 2011, 16 (2): 175-81.

Gilligan T: Social disparities and prostate cancer: mapping the gaps in our knowledge. Cancer Causes Control. 2005, 16 (1): 45-53.

Newschaffer CJ, Otani K, McDonald MK, Penberthy LT: Causes of death in elderly prostate cancer patients and in a comparison nonprostate cancer cohort. J Natl Cancer Inst. 2000, 92 (8): 613-21.

Frydenberg M, Wijesinha S: Diagnosing prostate cancer - what GPs need to know. Aust Fam Physician. 2007, 36 (5): 345-7.

Shimodaira K, Nakashima J, Nakagami Y, Hirasawa Y, Hashimoto T, Satake N, Gondo T, Namiki K, Ohori M, Ohno Y: Prognostic Value of Platelet Counts in Patients with Metastatic Prostate Cancer Treated with Endocrine Therapy. Urol J. 2020, 17 (1): 42-49.

Martínez-Salamanca JI, Ballesteros CM, Carballido Rodríguez J: [Epidemiological fundamentals of clinically localized prostate cancer]. Arch Esp Urol. 2011, 64 (8): 703-10.

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What causes prostate cancer?

The exact cause of prostate cancer is not known, but several factors have been identified that may increase the risk of developing the disease.

These include:

1. Age: The risk of prostate cancer increases with age, with most cases occurring in men over the age of 65.

2. Family history: Men with a family history of prostate cancer, particularly a father or brother with the disease, are at a higher risk.

3. Race: African American men have a higher risk of developing prostate cancer than men of other races.

4. Diet: A diet high in fat, particularly animal fat, may increase the risk of prostate cancer.

5. Obesity: Being overweight or obese may increase the risk of developing prostate cancer.

6. Hormones: High levels of testosterone and other male hormones may increase the risk of prostate cancer.

7. Inflammation: Chronic inflammation of the prostate, such as prostatitis, may increase the risk of prostate cancer.

8. Genetics: Certain inherited genetic mutations, such as those in the BRCA1 and BRCA2 genes, may increase the risk of prostate cancer.

It is important to note that having one or more of these risk factors does not mean that a man will definitely develop prostate cancer, and many men with prostate cancer have no known risk factors.

Additionally, research is ongoing to better understand the causes of prostate cancer and identify additional risk factors.

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