What is pathophysiology of Depression?

['Piŋë në ye athöörë yic']

Yeŋö ye cɔl 'pathophysiology of depression'?

Puɔ̈ɔ̈c de depression ee jam në puɔ̈ɔ̈c de kä ye röt looi në guɔ̈p de raan yic ku jɔl ya tɛ̈n yenë kek röt luɔɔi thïn ago raan ya cɔk lɔ në dhiɔp yic.

Aye yen mat thïn ëbën agut cï bï kä ye kek cɔk loi röt ya deet yiic, cïmën de kä ke puɔ̈ɔ̈c ë pïïr, kä ke puɔ̈ɔ̈c ë nhom, ku jɔl ya kä ye kɔc cɔk luui në röt, man ye kek cɔk ye kä ye kɔc cɔl adiɛɛr.

Kɔc cï rïthäc looi acï kä juëc lëu bïk kɔc ya cɔk liääp nhïïm bɛ̈n ya deet yiic, agut cï kä ye kek dhiëëth, kä ye kek röt waar në tän de neurotransmitter yic ku jɔl ya luɔɔi de kek, kä ye röt waar në tän de nhom yic ku jɔl ya luɔɔi de nhom, ku jɔl ya kä ye kɔc liääp nhïïm.

Kä ye tuaany de nhom cɔl depression looi aye yiic naŋ käjuëc ye kek cɔk loi röt, ku ka lëu bï käjuäc ke kek ya mat nëtök agokë ya tɔ̈ ëke ye tuaany de nhom cï riääk tënë kɔc wääc.

['Kä cï gɔ̈ɔ̈r']

PubMed/Medline https://www.nlm.nih.gov/databases/download/pubmed_medline.html

RefinedWeb https://arxiv.org/abs/2306.01116

Lai CH: The neural markers of MRI to differentiate depression and panic disorder. Prog Neuropsychopharmacol Biol Psychiatry. 2019, 91 (): 72-78.

Robinson RG, Chemerinski E, Jorge R: Pathophysiology of secondary depressions in the elderly. J Geriatr Psychiatry Neurol. 1999, 12 (3): 128-36.

Krishnan KR, McDonald WM, Doraiswamy PM, Tupler LA, Husain M, Boyko OB, Figiel GS, Ellinwood EH: Neuroanatomical substrates of depression in the elderly. Eur Arch Psychiatry Clin Neurosci. 1993, 243 (1): 41-6.

Olsen TS: Pathophysiology of the migraine aura: the spreading depression theory. Brain. 1995, 118 ( Pt 1) (): 307-8.

Normann C: Towards a new model for cellular pathophysiology in affective disorder. Acta Neuropsychiatr. 2000, 12 (3): 77-80.

Adler UC, Marques AH, Calil HM: Inflammatory aspects of depression. Inflamm Allergy Drug Targets. 2008, 7 (1): 19-23.

Rihmer Z, Seregi K, Rihmer A: Parkinson's disease and depression. Neuropsychopharmacol Hung. 2004, 6 (2): 82-5.

['Wɛ̈t cï lueel: wal']

['Wɛbthait kën ee piööc ku wël tɔ̈u thïn ku acie kë ye looi bï kɔc ke akïm ya lɛ̈k wala bï kɔc ke luɔi ya kony.']

['Wël cï kek ya lueel në ye athöör kënë yic acïï lëu bï kek ya kony agonë tuanytuɛny ya ŋic ku bï kek ya kony, ku kɔc wïc kuɔɔny de akïm adhil akïm de akïm ya thiëëc bï kek ya kony.']

['Tiɛ̈ŋë kä ye kuɔɔny de neural net looi, man ye kä ye bɛ̈n në kä cï kek ya thiëëc yiic, aye kek cɔk tɔ̈ ëke cïï kek ye deet yiic në thɛɛr juëc yiic. Cïmën de, ciin de kɔc cï kek yök ëke tuany.']

['Thïëc wɛ̈t akïmdu ka raan dɛ̈t wënë cï piöc ë pialgup wënë cï yök në biäk de tuaany. Duk wɛ̈t akïm ye kuɛ̈ɛ̈c nhom cɔk alɔn cï yen ya kë cï kueen në wɛbthait kënnë yic. Na ye tak ke yïn nɔŋ kë wïc bë yï kony në tuany, cɔl 911 ka lɔɔr në ɣön akïm tɔ̈u të thiääk ke yï në kaam thiin koor yic. Acïn akïm-tuany ye thiääk në yen në wɛbthait kënnë yic ka luɔ̈i de. BioMedLib ka kɔc cï luöi, ka raan ëbɛ̈n ye luui në yen në wɛbthait kënnë yic, acïn kë ye lueel, ye lueel ka ye lueel, në kë de wël cï kek gɔ̈ɔ̈r në ye athöör kënnë yic ka luɔ̈i de.']

['Wɛ̈t cï lueel: copyright']

['Lööŋ ke Digital Millennium Copyright Act de 1998, 17 U.S.C. § 512 (ye DMCA) ee kɔc ye käke kɔc gɔ̈t gam ke kä tɔ̈ në Internet aye käken tɔ̈ në U.S. copyright law dhoŋ kɔ̈th. ']

['Na ye gam në yith ke këriɛ̈ɛ̈c ka kä cï gɔ̈ɔ̈r tɔ̈ në wɛbthaitda ka kuɔɔnyda yic acï löŋ de gël de kä cï gɔ̈ɔ̈r dhoŋ kɔ̈u, ke yïn (ka raan ye yïn luɔ̈ɔ̈i) alëu ba ɣok tuɔ̈c wɛ̈t bï këriɛ̈ɛ̈c ka kä cï gɔ̈ɔ̈r nyaai, ka bï yïn pëën ba lɔ thïn. ']

["Wël aa bë ke tuɔɔc në athöör yic në email (tïŋ 'Rin de athöör' në biäk de email)."]

['DMCA ee wïc lɔnadɛ̈ ke kë ca lueel de kä cï keek gɔ̈ɔ̈r cï keek luɔ̈ɔ̈i anɔŋic wël cï keek gɔ̈ɔ̈r: (1) luɛɛl de kä cï keek luɔ̈ɔ̈i cï keek gɔ̈ɔ̈r cï keek luɔ̈ɔ̈i cï keek lueel; (2) luɛɛl de kä cï keek gɔ̈ɔ̈r cï keek lueel ku wël cï keek lueel bï keek cɔk lëu bïkë kä cï keek gɔ̈ɔ̈r yök; (3) wël bï yïn ke kɔn ya kɔɔr, nɔŋiic adrɛ̈ɛ̈rdu, namba de telepun ku adrɛ̈ɛ̈r de imeel; (4) wɛ̈t cï lueel në yï nhom lɔnadɛ̈ ke yïn ye gam ke kë cï gɔ̈ɔ̈r cï looi në kueer cï yïn ye gaam acie gam në raan de kä cï keek gɔ̈ɔ̈r cï keek luɔ̈ɔ̈i, ka raan de lööŋ, ka në luɔɔi de löŋ; ']

['(5) athöör cï yïn gätpiny në awuɔ̈c de wɛ̈t lueth, lɔnadɛ̈ ke wël tɔ̈ në athöör yic aye yith ku lɔnadɛ̈ ke yïn anɔŋ riɛl ba kä cï gɔ̈t ke lööŋ ke raan nɔŋ nhïïm ya looi në kë cï wuɔ̈ɔ̈c; ']

['Ku (6) ke ye kä cï gɔ̈t ke guɔ̈p ka kä cï gɔ̈t ke mɛ̈ɛ̈t de raan de kä cï luɔ̈ɔ̈i ka raan cï gäm riɛl bï luui në nyin de raan de kä cï luɔ̈ɔ̈i. ']

['Na këc wël cï gɔ̈ɔ̈r nhial tɔ̈u thïn kedhiɛ gɔ̈t, ke ka lëu bï këdun cï yïn gaam ya gääu.']

['Thiëc kek']

['Tuɔɔc email tënë ɣok na nɔŋ këdun thiëc/cï yïn tak.']

What is pathophysiology of depression?

Pathophysiology of depression refers to the study of the disordered physiological processes or mechanisms that are responsible for the development and progression of depression.

It involves understanding the underlying biological, neurological, and psychological factors that contribute to the onset and persistence of depressive symptoms.

Researchers have identified several potential causes and mechanisms that may contribute to depression, including genetic factors, alterations in neurotransmitter levels and activity, changes in brain structure and function, and environmental stressors.

The pathophysiology of depression is complex and multifaceted, and it is likely that a combination of these factors contributes to the development of the disorder in different individuals.

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