Puɔ̈ɔ̈c de tuany ë cancer de nhom ee rot gɛɛi në kä ye röt looi ku jɔl ya tän yenë tuany de nhom rot luɔɔi thïn.
Lung cancer ee tuany ril yic ye rot looi të cenë tuanytuɛɛny ke cells röt juak apɛi ku ye kek tek yiic në tuɛnytuɛɛny ke lungs yiic.
Käm käk alëu bïk tuanytuɛɛny looi ku lek në biäk kɔ̈k ke guɔ̈p yic, ku ka ye kä juëc kɔ̈k bɛ̈i.
Kë ye cɔl 'pathophysiology of lung cancer' ee yen naŋ kä juëc ye kek cɔk loi röt, agut cï kä ye röt waar në genetic yic, kä ye kek liääp në piny yic, ku jɔl ya tɛ̈n ye kek pïïr thïn.
Gɛ̈ɛ̈r de kä ke genetic alëu bï rot ya looi në DNA de lung cells yic, man ye cell ya cɔk cil ku bï ya tek.
Kä cï röt waar kä yiic alëu bï kek ya yök në kɔc yiic ka bï kek ya yök, ku ka lëu bïk ya bɛ̈n në kë de kä ye tuany cɔl cancer bɛ̈i, cïmën de tol de miök, radon, asbestos, ku jɔl ya aliir ye kɔc liääp.
Lung cancer alëu bï ya tekic në biäk kaa rou: small cell lung cancer (SCLC) ku non-small cell lung cancer (NSCLC). NSCLC aye tekic në biäk kaa diäk: adenocarcinoma, squamous cell carcinoma, ku large cell carcinoma.
Kä ye tuany cɔl 'pathophysiology' de tuanytuɛɛny ke yïc puɔ̈u nyuɔɔth alëu bï ya wuɔ̈ɔ̈c, në kë de aciëëk wääc ye kek röt geer yiic ku jɔl ya tɛ̈n yenë kek bɛɛr ya luui thïn në wal.
Puɔ̈ɔ̈c de tuany ë cancer de nhom ee rot looi në kaam de cancer cells kenë adit thiääk kenë kek, agut cï puɔ̈ɔ̈c de gël de guɔ̈p.
Käm 'cancer cells' alëu bïk ajuɛɛr gël de guɔ̈p ya gël, ago kek ya cɔk cil ku bï kek ya tekpiny në kë cïï kek lëu bïk ya looi.
Kë juɛ̈c, ɣän ke piiny ke tuany alëu bïk cil de tuany cɔk juak rot ku bï kek ya tekpiny në ɣän kɔ̈k peei yiic në kë de bïk käjuäc ke tuany ya kony.
Puɔ̈ɔ̈c de tuany ë cancer de cuäŋ ee ya kë rilic apɛi, ku kɔc ye rïthäc looi aye luui në yen agokë kä tɔ̈ thïn ya deet apath agokë ya luui në kek agokë ya yiɛ̈knhial ku bï kek ya yiɛ̈knhial agokë tuanytuɛɛny ya yiɛ̈knhial ku bï kek ya yiɛ̈knhial.
Li Z, Qian Y, Li W, Liu L, Yu L, Liu X, Wu G, Wang Y, Luo W, Fang F, Liu Y, Song F, Cai Z, Chen W, Huang W: Human Lung Adenocarcinoma-Derived Organoid Models for Drug Screening. iScience. 2020, 23 (8): 101411.
Nurwidya F, Syahruddin E, Yunus F: Pain management in lung cancer. Adv Respir Med. 2016, 84 (6): 331-336.
Khan KA, Kennedy MP, Moore E, Crush L, Prendeville S, Maher MM, Burke L, Henry MT: Radiological characteristics, histological features and clinical outcomes of lung cancer patients with coexistent idiopathic pulmonary fibrosis. Lung. 2015, 193 (1): 71-7.
Paramanantham A, Asfiya R, Das S, McCully G, Srivastava A: Extracellular Vesicle (EVs) Associated Non-Coding RNAs in Lung Cancer and Therapeutics. Int J Mol Sci. 2022, 23 (21): .
Lee D, Kim Y, Chung C: Scientific Validation and Clinical Application of Lung Cancer Organoids. Cells. 2021, 10 (11): .
Mucchietto V, Crespi A, Fasoli F, Clementi F, Gotti C: Neuronal Acetylcholine Nicotinic Receptors as New Targets for Lung Cancer Treatment. Curr Pharm Des. 2016, 22 (14): 2160-9.
['Wɛ̈t cï lueel: wal']
['Wɛbthait kën ee piööc ku wël tɔ̈u thïn ku acie kë ye looi bï kɔc ke akïm ya lɛ̈k wala bï kɔc ke luɔi ya kony.']
['Wël cï kek ya lueel në ye athöör kënë yic acïï lëu bï kek ya kony agonë tuanytuɛny ya ŋic ku bï kek ya kony, ku kɔc wïc kuɔɔny de akïm adhil akïm de akïm ya thiëëc bï kek ya kony.']
['Tiɛ̈ŋë kä ye kuɔɔny de neural net looi, man ye kä ye bɛ̈n në kä cï kek ya thiëëc yiic, aye kek cɔk tɔ̈ ëke cïï kek ye deet yiic në thɛɛr juëc yiic. Cïmën de, ciin de kɔc cï kek yök ëke tuany.']
['Thïëc wɛ̈t akïmdu ka raan dɛ̈t wënë cï piöc ë pialgup wënë cï yök në biäk de tuaany. Duk wɛ̈t akïm ye kuɛ̈ɛ̈c nhom cɔk alɔn cï yen ya kë cï kueen në wɛbthait kënnë yic. Na ye tak ke yïn nɔŋ kë wïc bë yï kony në tuany, cɔl 911 ka lɔɔr në ɣön akïm tɔ̈u të thiääk ke yï në kaam thiin koor yic. Acïn akïm-tuany ye thiääk në yen në wɛbthait kënnë yic ka luɔ̈i de. BioMedLib ka kɔc cï luöi, ka raan ëbɛ̈n ye luui në yen në wɛbthait kënnë yic, acïn kë ye lueel, ye lueel ka ye lueel, në kë de wël cï kek gɔ̈ɔ̈r në ye athöör kënnë yic ka luɔ̈i de.']
['Wɛ̈t cï lueel: copyright']
['Lööŋ ke Digital Millennium Copyright Act de 1998, 17 U.S.C. § 512 (ye DMCA) ee kɔc ye käke kɔc gɔ̈t gam ke kä tɔ̈ në Internet aye käken tɔ̈ në U.S. copyright law dhoŋ kɔ̈th. ']
['Na ye gam në yith ke këriɛ̈ɛ̈c ka kä cï gɔ̈ɔ̈r tɔ̈ në wɛbthaitda ka kuɔɔnyda yic acï löŋ de gël de kä cï gɔ̈ɔ̈r dhoŋ kɔ̈u, ke yïn (ka raan ye yïn luɔ̈ɔ̈i) alëu ba ɣok tuɔ̈c wɛ̈t bï këriɛ̈ɛ̈c ka kä cï gɔ̈ɔ̈r nyaai, ka bï yïn pëën ba lɔ thïn. ']
["Wël aa bë ke tuɔɔc në athöör yic në email (tïŋ 'Rin de athöör' në biäk de email)."]
['DMCA ee wïc lɔnadɛ̈ ke kë ca lueel de kä cï keek gɔ̈ɔ̈r cï keek luɔ̈ɔ̈i anɔŋic wël cï keek gɔ̈ɔ̈r: (1) luɛɛl de kä cï keek luɔ̈ɔ̈i cï keek gɔ̈ɔ̈r cï keek luɔ̈ɔ̈i cï keek lueel; (2) luɛɛl de kä cï keek gɔ̈ɔ̈r cï keek lueel ku wël cï keek lueel bï keek cɔk lëu bïkë kä cï keek gɔ̈ɔ̈r yök; (3) wël bï yïn ke kɔn ya kɔɔr, nɔŋiic adrɛ̈ɛ̈rdu, namba de telepun ku adrɛ̈ɛ̈r de imeel; (4) wɛ̈t cï lueel në yï nhom lɔnadɛ̈ ke yïn ye gam ke kë cï gɔ̈ɔ̈r cï looi në kueer cï yïn ye gaam acie gam në raan de kä cï keek gɔ̈ɔ̈r cï keek luɔ̈ɔ̈i, ka raan de lööŋ, ka në luɔɔi de löŋ; ']
['(5) athöör cï yïn gätpiny në awuɔ̈c de wɛ̈t lueth, lɔnadɛ̈ ke wël tɔ̈ në athöör yic aye yith ku lɔnadɛ̈ ke yïn anɔŋ riɛl ba kä cï gɔ̈t ke lööŋ ke raan nɔŋ nhïïm ya looi në kë cï wuɔ̈ɔ̈c; ']
['Ku (6) ke ye kä cï gɔ̈t ke guɔ̈p ka kä cï gɔ̈t ke mɛ̈ɛ̈t de raan de kä cï luɔ̈ɔ̈i ka raan cï gäm riɛl bï luui në nyin de raan de kä cï luɔ̈ɔ̈i. ']
['Na këc wël cï gɔ̈ɔ̈r nhial tɔ̈u thïn kedhiɛ gɔ̈t, ke ka lëu bï këdun cï yïn gaam ya gääu.']
['Thiëc kek']
['Tuɔɔc email tënë ɣok na nɔŋ këdun thiëc/cï yïn tak.']
What is pathophysiology of lung cancer?
The pathophysiology of lung cancer refers to the changes in the normal physiological processes and mechanisms that occur in the development and progression of lung cancer.
Lung cancer is a complex disease that arises from the uncontrolled growth and division of abnormal cells in the lungs.
These cells can form tumors and spread to other parts of the body, leading to various symptoms and complications.
The pathophysiology of lung cancer involves several factors, including genetic mutations, environmental factors, and lifestyle choices.
Genetic mutations can occur in the DNA of lung cells, leading to uncontrolled cell growth and division.
These mutations can be inherited or acquired, and they can be caused by exposure to carcinogens, such as tobacco smoke, radon, asbestos, and air pollution.
Lung cancer can be classified into two main types: small cell lung cancer (SCLC) and non-small cell lung cancer (NSCLC). NSCLC is further divided into three subtypes: adenocarcinoma, squamous cell carcinoma, and large cell carcinoma.
The pathophysiology of these types of lung cancer can differ, as they have different genetic mutations and respond differently to treatment.
The pathophysiology of lung cancer also involves the interaction between cancer cells and the surrounding tissue, including the immune system.
Cancer cells can evade the immune system, allowing them to grow and spread unchecked.
Additionally, the tumor microenvironment can promote tumor growth and metastasis by providing a supportive environment for cancer cells.
The pathophysiology of lung cancer is a complex and dynamic process, and researchers are continuously working to better understand the underlying mechanisms to develop more effective treatments and improve patient outcomes.
Disclaimer: medical
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