Menene ilimin halittar jiki na ciwon daji na hanji?
Pathophysiology na ciwon daji na hanji yana nufin hanyoyin da ke haifar da ci gaba da ci gaban ciwon daji na hanji.
Ciwon daji na hanji, wanda kuma aka sani da ciwon daji na hanji, wani nau'in ciwon daji ne wanda ke farawa a cikin hanji ko kuma makogwaro, wanda sassan babban hanji ne.
Yawanci yakan fara ne da girma da ake kira polyp, wanda zai iya zama ciwon daji a kan lokaci.
Pathophysiology na ciwon daji na hanji ya ƙunshi dalilai da yawa, gami da maye gurbi na kwayoyin halitta, kumburi, da abubuwan muhalli.
Canjin halittar kwayar halitta na iya faruwa a cikin DNA na ƙwayoyin hanji, wanda ke haifar da haɓakar ƙwayoyin cuta da rarrabuwa.
Ana iya gādan waɗannan canje-canjen ko kuma a samu, kuma suna iya shafan ƙwayoyin halitta dabam dabam da suke sa ƙwayoyin halitta su yi girma, su rarrabu, kuma su gyara kansu.
Kumburi a cikin hanji, wanda zai iya haifar da yanayi kamar cututtukan hanji, na iya ƙara haɗarin cutar kansa.
Kumburi na yau da kullun na iya haifar da sakin sinadarai waɗanda ke haɓaka haɓakar sel da rarrabuwa, mai yiwuwa yana haifar da ciwon kansa.
Abubuwan da ke tattare da muhalli, kamar abinci, salon rayuwa, da kuma kamuwa da wasu sinadarai, na iya taimakawa wajen ci gaban cutar sankarar hanji.
Abincin da ke da yawan jan nama da sarrafa shi, alal misali, an danganta shi da haɗarin cutar kansa.
Wasu abubuwa kamar su kiba, shan taba, da kuma rashin motsa jiki, suna iya sa mutum ya kamu da cutar.
Da zarar ciwon daji na hanji ya bunkasa, zai iya ci gaba ta matakai da yawa, daga farkon cutar kansa wanda ke iyakance ga hanji zuwa matakan ci gaba inda cutar kansa ta bazu zuwa wasu sassan jiki.
Kwayoyin cutar kansa na iya mamaye kyallen takarda da gabobin da ke kusa, kuma suna iya yaduwa ta hanyar lymphatic system ko jini zuwa wurare masu nisa, kamar hanta ko huhu.
Jiyya don ciwon daji na hanji yawanci ya ƙunshi haɗuwa da tiyata, chemotherapy, da radiation therapy, dangane da mataki da wurin cutar kansa.
Ganowa da wuri da magani sune mabuɗin don inganta sakamako, saboda cutar sankarar hanji galibi ana iya warkewa idan aka kama ta a farkon matakan ta.
Bincike na kullum, kamar na hanji, zai iya taimaka wajen gano ciwon daji na hanji a lokacin da ya fara, lokacin da zai fi sauƙi a warkar da shi.
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Yagi T, Kubota E, Koyama H, Tanaka T, Kataoka H, Imaeda K, Joh T: Glucagon promotes colon cancer cell growth via regulating AMPK and MAPK pathways. Oncotarget. 2018, 9 (12): 10650-10664.
Sharma SH, Thulasingam S, Nagarajan S: Terpenoids as anti-colon cancer agents - A comprehensive review on its mechanistic perspectives. Eur J Pharmacol. 2017, 795 (): 169-178.
Keshk WA, Zineldeen DH, Wasfy RE, El-Khadrawy OH: Fatty acid synthase/oxidized low-density lipoprotein as metabolic oncogenes linking obesity to colon cancer via NF-kappa B in Egyptians. Med Oncol. 2014, 31 (10): 192.
Dongfeng D, An C, Shujia P, Jikai Y, Tao Y, Rui D, Kai T, Yafeng C, Jianguo L, Xilin D: Explanation of colon cancer pathophysiology through analyzing the disrupted homeostasis of bile acids. Afr Health Sci. 2014, 14 (4): 925-8.
Tammali R, Ramana KV, Srivastava SK: Aldose reductase regulates TNF-alpha-induced PGE2 production in human colon cancer cells. Cancer Lett. 2007, 252 (2): 299-306.
['Bayanin sanarwa: likita']
['Wannan shafin yanar gizon don ilimantarwa ne kawai ba don ba da shawara ko kuma ba da shawara ta likita ba.']
['Bai kamata a yi amfani da bayanin da aka bayar don gano ko magance matsalar lafiya ko cuta ba, kuma waɗanda suke neman shawarar likita na sirri ya kamata su tuntuɓi likitan da ke da lasisi.']
['Lura cewa hanyar sadarwar jijiyoyin da ke samar da amsoshin tambayoyin, ba ta da daidaito musamman idan ya zo ga abun cikin lamba. Misali, yawan mutanen da aka gano suna da takamaiman cuta.']
["Koyaushe nemi shawarar likitanka ko wani ƙwararren mai ba da lafiya game da yanayin likita. Kada ka taɓa yin watsi da shawarar likita ko jinkiri wajen neman ta saboda wani abu da ka karanta a wannan rukunin yanar gizon. Idan kuna tsammanin kuna da matsalar gaggawa ta likita, kira 911 ko je zuwa ɗakin gaggawa mafi kusa nan da nan. Babu wata alaƙar likita da mara lafiya da aka ƙirƙira ta wannan rukunin yanar gizon ko amfaninsa. BioMedLib ko ma'aikatanta, ko kowane mai ba da gudummawa ga wannan rukunin yanar gizon, ba su yin kowane wakilci, bayyane ko a bayyane, dangane da bayanan da aka bayar a nan ko amfaninsa."]
['Bayanin haƙƙin mallaka']
['Dokar haƙƙin mallaka ta Millennium ta 1998, 17 U.S.C. § 512 (DMCA) tana ba da damar neman masu haƙƙin mallaka waɗanda suka yi imanin cewa kayan da ke bayyana a Intanet sun keta haƙƙinsu a ƙarƙashin dokar haƙƙin mallaka ta Amurka. ']
['Idan kun yi imani da gaskiya cewa duk wani abun ciki ko kayan da aka samar dangane da gidan yanar gizon mu ko ayyukanmu ya keta haƙƙin mallaka, ku (ko wakilin ku) na iya aiko mana da sanarwa don neman cire abun ciki ko kayan, ko toshe damar zuwa gare shi. ']
["Dole ne a aika da sanarwa a rubuce ta hanyar imel (duba sashin 'Saduwa' don adireshin imel). "]
['DMCA tana buƙatar sanarwar ku game da zargin keta haƙƙin mallaka ya haɗa da waɗannan bayanan: (1) bayanin aikin haƙƙin mallaka wanda shine batun zargin cin zarafin; (2) bayanin abin da ake zargi da cin zarafin abun ciki da kuma isasshen bayani don ba mu damar gano abun ciki; (3) bayanin tuntuɓar ku, gami da adireshin ku, lambar tarho da adireshin imel; (4) sanarwa daga gare ku cewa kuna da kyakkyawan imani cewa abun cikin yadda ake korafin ba shi da izinin mai haƙƙin mallaka, ko wakilinsa, ko ta aikin kowace doka; ']
['(5) sanarwa daga gare ku, wanda aka sanya hannu a ƙarƙashin hukuncin shaidar zur, cewa bayanin da ke cikin sanarwar daidai ne kuma kuna da ikon aiwatar da haƙƙin mallaka wanda ake zargin an keta shi; ']
['da (6) sa hannu na zahiri ko na lantarki na mai haƙƙin mallaka ko mutumin da aka ba shi izinin yin aiki a madadin mai haƙƙin mallaka. ']
['Rashin hada dukkan bayanan da ke sama na iya haifar da jinkiri wajen aiwatar da korafin ka.']
['Tuntuɓi']
['Da fatan za a aiko mana da imel tare da kowace tambaya / shawara.']
What is pathophysiology of colon cancer?
The pathophysiology of colon cancer refers to the underlying mechanisms and processes that lead to the development and progression of colon cancer.
Colon cancer, also known as colorectal cancer, is a type of cancer that begins in the colon or rectum, which are parts of the large intestine.
It typically starts as a growth called a polyp, which can develop into cancer over time.
The pathophysiology of colon cancer involves several factors, including genetic mutations, inflammation, and environmental factors.
Genetic mutations can occur in the DNA of colon cells, leading to uncontrolled cell growth and division.
These mutations can be inherited or acquired, and they can affect various genes involved in cell growth, division, and repair.
Inflammation in the colon, which can be caused by conditions such as inflammatory bowel disease, can also increase the risk of colon cancer.
Chronic inflammation can lead to the release of chemicals that promote cell growth and division, potentially leading to the development of cancer.
Environmental factors, such as diet, lifestyle, and exposure to certain chemicals, can also contribute to the development of colon cancer.
A diet high in red and processed meats, for example, has been linked to an increased risk of colon cancer.
Other factors, such as obesity, smoking, and lack of physical activity, can also increase the risk.
Once colon cancer develops, it can progress through several stages, from early-stage cancer that is confined to the colon to more advanced stages where the cancer has spread to other parts of the body.
The cancer cells can invade nearby tissues and organs, and may also spread through the lymphatic system or bloodstream to distant sites, such as the liver or lungs.
Treatment for colon cancer typically involves a combination of surgery, chemotherapy, and radiation therapy, depending on the stage and location of the cancer.
Early detection and treatment are key to improving outcomes, as colon cancer is often curable when caught in its early stages.
Regular screening, such as colonoscopy, can help detect colon cancer at its earliest stages, when it is most treatable.
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