Olee otú e si achọpụta na mmadụ nwere ọrịa Alzheimer?
A na-achọpụta ọrịa Alzheimer site n'ịchịkọta ụzọ dị iche iche, gụnyere nyocha ahụike zuru ezu, ule cognitive na neuropsychological, ihe oyiyi ụbụrụ, na usoro nke iwepụ ihe ndị ọzọ nwere ike ịkpata ya.
1. Nyocha ahụike: Dọkịta ga-enyocha ahụ́ ya ma depụta ihe nile banyere ọrịa ya iji chọpụta ma è nwere ihe ndị ọzọ nwere ike ime ka ọ ghara icheta ihe ma ọ bụ ghara ịma ihe ọ na-eme, dị ka nsogbu akwara thyroid, ụkọ vitamin, ma ọ bụ ọrịa ụbụrụ.
2. Nnyocha ọgụgụ isi na nke akparamàgwà mmadụ: Nnyocha ndị a na-enyocha ebe nchekwa, asụsụ, idozi nsogbu, na ọrụ ọgụgụ isi ndị ọzọ iji chọpụta ókè nkwarụ ọgụgụ isi dị na ya na ịmata ọdịiche dị n'etiti ọnwụ ncheta nkịtị metụtara afọ na dementia.
3. Nyocha ụbụrụ: Nyocha ụbụrụ a na-akpọ magnetic resonance imaging (MRI) ma ọ bụ computed tomography (CT) pụrụ inye aka ịchọpụta mgbanwe ndị na-eme n'ụbụrụ bụ́ ndị pụrụ igosi ọrịa Alzheimer.
A pụkwara iji nyocha positron emission tomography (PET) mee ihe iji tụọ ọkwa nke ụfọdụ protein ndị metụtara ọrịa Alzheimer.
4. Nnyocha ọbara: Nnyocha e mere n'oge na-adịbeghị anya egosiwo na nnyocha ọbara ụfọdụ pụrụ inye aka ịchọpụta ọrịa Alzheimer site n'ịtụle ọkwa nke protein ma ọ bụ ihe ndị na-egosi na ọrịa ahụ na-efe efe.
5. Usoro a na-eji ewepụ ọrịa Alzheimer: Ebe ọ bụ na ọ dịghị otu ụzọ a ga-esi chọpụta ọrịa Alzheimer n'ụzọ doro anya, a na-ejikarị ihe ndị ọzọ pụrụ ịkpata mgbaàmà ndị yiri ọrịa dementia eme nchọpụta.
Ọ dị mkpa iburu n'uche na ọ bụ nanị mgbe mmadụ nwụsịrị ka a pụrụ ịchọpụta ọrịa Alzheimer n'ụzọ doro anya site n'inyocha ụbụrụ.
Otú ọ dị, usoro nchọpụta ọrịa ndị a na-eji eme ihe ugbu a pụrụ inye obi ike dị ukwuu maka nchọpụta ọrịa mgbe onye ahụ ka dị ndụ.
Ịchọpụta ọrịa n'oge dị mkpa maka ịmalite ọgwụgwọ na ime atụmatụ maka ọdịnihu.
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Rubin R: New Test to Help Diagnose Alzheimer Disease. JAMA. 2022, 327 (23): 2281.
[Blood Based Biomarker for Optimization of Early and Differential Diagnosis of Alzheimer's Dementia]. Fortschr Neurol Psychiatr. 2022, 90 (7-08): 326-335.
Kapp MB: Physicians' legal duties regarding the use of genetic tests to predict and diagnose Alzheimer disease. J Leg Med. 2000, 21 (4): 445-75.
Britschgi M, Wyss-Coray T: Blood protein signature for the early diagnosis of Alzheimer disease. Arch Neurol. 2009, 66 (2): 161-5.
Volicer L, Berman SA, Cipolloni PB, Mandell A: Persistent vegetative state in Alzheimer disease. Does it exist? Arch Neurol. 1997, 54 (11): 1382-4.
Imabayashi E, Saitoh Y, Tsukamoto T, Sakata M, Takano H: Combination of Astrogliosis and Phosphorylated Tau for the Preclinical Diagnosis of Alzheimer Disease Using 3-Dimensional Stereotactic Surface Projection Images With 18 F-THK5351. Clin Nucl Med. 2022, 47 (12): 1066-1068.
Martínez A, Lahiri DK, Giacobini E, Greig NH: Advances in Alzheimer therapy: understanding pharmacological approaches to the disease. Curr Alzheimer Res. 2009, 6 (2): 83-5.
Nkwupụta: ọgwụgwọ
A na-enye weebụsaịtị a maka ebumnuche agụmakwụkwọ na ozi naanị ma ọ bụghị inye ndụmọdụ ahụike ma ọ bụ ọrụ ọkachamara.
E kwesịghị iji ihe ọmụma e nyere mee ihe maka ịchọpụta ma ọ bụ ịgwọ nsogbu ahụ ike ma ọ bụ ọrịa, ndị na-achọ ndụmọdụ ahụike onwe ha kwesịrị ịgakwuru dọkịta nwere ikike.
Biko rịba ama na netwọkụ akwara nke na-emepụta azịza nye ajụjụ ndị ahụ, bụ ihe na-ezighi ezi mgbe ọ na-abịa na ọnụọgụ ọnụọgụ. Dịka ọmụmaatụ, ọnụọgụ ndị mmadụ chọpụtara na ọrịa akọwapụtara.
Na-achọkarị ndụmọdụ nke dọkịta gị ma ọ bụ onye na-ahụ maka ahụike ọzọ ruru eru banyere ọnọdụ ahụike. Elegharala ndụmọdụ ahụike ọkachamara anya ma ọ bụ na-egbu oge n'ịchọ ya n'ihi ihe ị gụrụ na weebụsaịtị a. Ọ bụrụ na i chere na ị nwere ike ịnweta mberede ahụike, kpọọ 911 ma ọ bụ gaa n'ọnụ ụlọ mberede kacha nso ozugbo. Enweghị mmekọrịta dọkịta na onye ọrịa na-emepụta site na weebụsaịtị a ma ọ bụ ojiji ya. Ma BioMedLib ma ndị ọrụ ya, ma onye ọ bụla na-enye aka na weebụsaịtị a, anaghị eme nkwupụta ọ bụla, kwupụta ma ọ bụ kwupụta, gbasara ozi enyere ebe a ma ọ bụ ojiji ya.
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Mkparịta ụka
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How is alzheimer diagnosed?
Alzheimer's disease is diagnosed through a combination of methods, including a thorough medical evaluation, cognitive and neuropsychological tests, brain imaging, and the process of elimination of other possible causes.
1. Medical evaluation: A doctor will perform a physical examination and take a detailed medical history to rule out other possible causes of memory loss or cognitive decline, such as thyroid problems, vitamin deficiencies, or brain tumors.
2. Cognitive and neuropsychological tests: These tests assess memory, language, problem-solving, and other cognitive functions to determine the extent of cognitive impairment and to differentiate between normal age-related memory loss and dementia.
3. Brain imaging: Magnetic resonance imaging (MRI) or computed tomography (CT) scans can help identify structural changes in the brain that may indicate Alzheimer's disease.
Positron emission tomography (PET) scans can also be used to measure the levels of certain proteins associated with Alzheimer's disease.
4. Blood tests: Recent research has shown that certain blood tests can help diagnose Alzheimer's disease by measuring the levels of specific proteins or biomarkers associated with the disease.
5. Process of elimination: Since there is no single definitive test for Alzheimer's disease, diagnosis often involves ruling out other possible causes of dementia-like symptoms.
It is important to note that a definitive diagnosis of Alzheimer's disease can only be made after death through an examination of brain tissue.
However, current diagnostic methods can provide a high level of certainty for a clinical diagnosis while the person is still alive.
Early diagnosis is important for starting treatment and planning for the future.
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