What is pathophysiology of Depression?

['Tega amatwi iyi paji']

Ese indwara yo kwiheba iteye ite?

Imikorere y'indwara y'agahinda gakabije yerekeza ku nyigo y'imikorere mibi y'umubiri cyangwa imikorere ishinzwe iterambere n'iterambere ry'agahinda gakabije.

Bikubiyemo gusobanukirwa ibintu by'ibanze, imikorere y'ubwonko n'imitekerereze bigira uruhare mu gutangira no kuramba kw'ibimenyetso by'ihungabana.

Abashakashatsi bagaragaje impamvu nyinshi zishobora gutera indwara yo kwiheba, harimo iziterwa n'umuryango umuntu avukamo, imihindagurikire y'imikorere y'ubwonko, imihindagurikire y'imiterere n'imikorere y'ubwonko ndetse n'ibibangamira ibidukikije.

Imikorere y'indwara y'agahinda gakabije iragoye kandi ifite ibintu byinshi biyihishe inyuma, kandi birashoboka ko ibyo bintu byombi bituma abantu batandukanye barwara iyo ndwara.

['Ibitabo']

PubMed/Medline https://www.nlm.nih.gov/databases/download/pubmed_medline.html

RefinedWeb https://arxiv.org/abs/2306.01116

Lai CH: The neural markers of MRI to differentiate depression and panic disorder. Prog Neuropsychopharmacol Biol Psychiatry. 2019, 91 (): 72-78.

Robinson RG, Chemerinski E, Jorge R: Pathophysiology of secondary depressions in the elderly. J Geriatr Psychiatry Neurol. 1999, 12 (3): 128-36.

Krishnan KR, McDonald WM, Doraiswamy PM, Tupler LA, Husain M, Boyko OB, Figiel GS, Ellinwood EH: Neuroanatomical substrates of depression in the elderly. Eur Arch Psychiatry Clin Neurosci. 1993, 243 (1): 41-6.

Olsen TS: Pathophysiology of the migraine aura: the spreading depression theory. Brain. 1995, 118 ( Pt 1) (): 307-8.

Normann C: Towards a new model for cellular pathophysiology in affective disorder. Acta Neuropsychiatr. 2000, 12 (3): 77-80.

Adler UC, Marques AH, Calil HM: Inflammatory aspects of depression. Inflamm Allergy Drug Targets. 2008, 7 (1): 19-23.

Rihmer Z, Seregi K, Rihmer A: Parkinson's disease and depression. Neuropsychopharmacol Hung. 2004, 6 (2): 82-5.

['Icyitonderwa: ubuvuzi']

["Uru rubuga rwashyiriweho kwigisha abantu no kubaha amakuru gusa, ntirutanga inama ku birebana n'ubuvuzi cyangwa ngo rukore nk'ikigo gitanga serivisi z'ubuvuzi."]

["Amakuru atangwa n'iyi porogaramu ntagomba gukoreshwa mu gusuzuma cyangwa kuvura ikibazo cy'uburwayi cyangwa indwara runaka, kandi abashaka inama z'ubuvuzi bagombye kugisha inama umuganga ubifitiye uburenganzira."]

['Nyamuneka menya ko imbuga nkoranyambaga zitanga ibisubizo kubibazo, ntabwo zifite ukuri mugihe kijyanye numubare. Kurugero, umubare wabantu basanzwemo indwara runaka.']

["Buri gihe ujye usaba inama umuganga wawe cyangwa undi muntu wemewe mu bijyanye n'ubuzima ku bijyanye n'uburwayi. Ntuzigere wirengagiza inama z'abaganga cyangwa ngo utinde kuzisaba bitewe n'ikintu wasomye kuri uru rubuga. Niba utekereza ko ufite ikibazo cyihutirwa, hamagara 911 cyangwa ujye ku ivuriro rikwegereye. Nta mubano hagati y'umuganga n'umurwayi ukorwa n'uru rubuga cyangwa ikoreshwa ryarwo. Yaba BioMedLib cyangwa abakozi bayo, cyangwa undi muntu wese wagize uruhare kuri uru rubuga, nta gihamya batanga, yaba igaragara cyangwa itagaragara, ku bijyanye n'amakuru atangwa hano cyangwa ikoreshwa ryayo."]

["Ibirego: uburenganzira bw'umuhanzi"]

["Itegeko ryo mu 1998 ryerekeye uburenganzira bw'ibihumbi by'ibihumbi by'ibihumbi by'ibihumbi, 17 U.S.C. § 512 (DMCA) ritanga ubujurire ku bafite uburenganzira bw'umuhanzi bemera ko ibintu bigaragara kuri interineti bibangamira uburenganzira bwabo hakurikijwe amategeko y'uburenganzira bw'umuhanzi muri Amerika. "]

['Niba wemera ko ibintu cyangwa ibikoresho byashyizwe ku rubuga rwacu cyangwa serivisi bitubahiriza uburenganzira bwawe, wowe (cyangwa umuhagarariye) ushobora kutwoherereza ubutumwa udusaba ko ibyo bintu cyangwa ibikoresho bikurwaho, cyangwa ko utabikoresha.']

['Itangazo rigomba koherezwa mu nyandiko kuri interineti (reba ahanditse "Kwitaba" kugira ngo ubone aderesi ya interineti). ']

["DMCA isaba ko imenyesha ryawe ry'ikirego cyo kuvutswa uburenganzira rikubiyemo amakuru akurikira: (1) ibisobanuro by'igikorwa kirengera uburenganzira bw'umuhanzi kivugwaho kuvutswa uburenganzira; (2) ibisobanuro by'ibikubiyemo bivugwa ko ari ukurenga ku mategeko n'amakuru ahagije atuma dushobora kubona ibikubiyemo; (3) amakuru yo kuguhamagaraho, harimo aderesi yawe, nomero ya terefone na aderesi imeyiri; (4) inyandiko yawe ivuga ko ufite icyizere ko ibikubiyemo mu buryo bwatanzwe nta burenganzira bifite na nyiri uburenganzira bw'umuhanzi, cyangwa umukozi we, cyangwa mu mategeko ayo ari yo yose; "]

["(5) inyandiko yawe isinyweho, uhanishwa kubeshya, yemeza ko amakuru ari mu itangazo ari ukuri kandi ko ufite ububasha bwo kurengera uburenganzira bw'umuhanzi uvugwaho kubwamburwa; "]

["kandi (6) umukono usanzwe cyangwa wa elegitoroniki w'ufite uburenganzira ku nyandiko cyangwa uw'umuntu wabiherewe uburenganzira bwo gukora mu izina ry'ufite uburenganzira ku nyandiko. "]

['Kudatanga amakuru yose yavuzwe haruguru bishobora gutuma ikibazo cyawe gitinda gukemurwa.']

['Uko twavugana na we']

['Ohereza imeri ikibazo / igitekerezo.']

What is pathophysiology of depression?

Pathophysiology of depression refers to the study of the disordered physiological processes or mechanisms that are responsible for the development and progression of depression.

It involves understanding the underlying biological, neurological, and psychological factors that contribute to the onset and persistence of depressive symptoms.

Researchers have identified several potential causes and mechanisms that may contribute to depression, including genetic factors, alterations in neurotransmitter levels and activity, changes in brain structure and function, and environmental stressors.

The pathophysiology of depression is complex and multifaceted, and it is likely that a combination of these factors contributes to the development of the disorder in different individuals.

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