How is Alzheimer diagnosed?

['Wande ruwu adǝ fanne']

Jilibi men alzheimer dǝ asutin?

Kwasa Alzheimerbe dә duluwa kadan asutin, suronzәn kulashi liyitabe ngәla-ngәla, jarabtә ilmube-a neuropsychologicalbe-a, foto kәrәnbe-a, kuru duluwuwa suwudinwa gade soye tutuluwu-a mbeji.

1. Liyitaye ngәla ro kulastә: Liyitabe nәm ngәla ro kulastә kuru tarihi nәlewabe bayanjin alamawa gade takcin ma au hangal hangalye bannatәye, alama kaziyi thyroidbe so, vitamin mbautәye so, au kәrәn tutumaye so.

2. Jarabtǝ hangalbe-a kǝndǝgaram hangalbe-a: Jarabtǝwa adǝbe hangal gǝnatǝ-a, tǝlam-a, kaziyi galtǝ-a, kuru cidawa hangalbe gade so-a asuza nasha hangal gǝnatǝbe fǝlango-a kuru asutu hangalbe-a kǝndǝgaram-a kate am ngǝli gana-a am hangal gǝnatǝbe-a gayirtǝ-a.

3. Brain imaging: Magnetic resonance imaging (MRI) au computed tomography (CT) scans dǝ banazǝyin kǝndaram faltǝ kǝrǝnbe dǝga asutin shido Alzheimer's disease fǝlezǝyin ma.

Positron emission tomography (PET) scansdə faidatə ngalzə proteinwa kwasuwa Alzheimerbe suwudin laa ngəwu asutəgə.

4. Kulashi buye: Kulashi karǝngǝbe fǝlezǝna kulashi buye laa soye banazǝyin kwasa Alzheimerbe notǝro proteinwa taganasbe ngǝwu au awowa kwasa dǝga bayanzǝyinma so fǝleta men.

5. Duluwu tutuluwu: Kwasa Alzheimerbe dǝro jarabtǝ tawadǝbe fal ba dǝro, bayan donyi tǝdin ma dǝ ngǝwusoro awowa gade donyi dementia-a samunzǝyin ma so dǝga tutuluyin.

Notә tawadә ro faida'a dә shima kwasa Alzheimerbe dә bayan tawatkәgәna ma dә ngawo kәrmuyen do nasha kәrәn dә kulastә men tuwandin.

Sonyayi, nzunduwa kwasa ashirbe kurma dǝ ye bayan cin kǝla kwasa shima dǝ tǝrayinma woktu do kam shima dǝ tǝrayinma dǝn.

Kulashi burotǝ dǝ kurun baditǝ-a fuwu ro dawari kǝndobe-a ro faida'a.

['Wutəgə']

PubMed/Medline https://www.nlm.nih.gov/databases/download/pubmed_medline.html

RefinedWeb https://arxiv.org/abs/2306.01116

Liu SS, Zhu SQ: [Correlation between Alzheimer disease and cataract]. Zhonghua Yan Ke Za Zhi. 2017, 53 (4): 314-316.

Gauthier S: Practical guidelines for the antemortem diagnosis of senile dementia of the Alzheimer type. Prog Neuropsychopharmacol Biol Psychiatry. 1985, 9 (5-6): 491-5.

Rubin R: New Test to Help Diagnose Alzheimer Disease. JAMA. 2022, 327 (23): 2281.

[Blood Based Biomarker for Optimization of Early and Differential Diagnosis of Alzheimer's Dementia]. Fortschr Neurol Psychiatr. 2022, 90 (7-08): 326-335.

Kapp MB: Physicians' legal duties regarding the use of genetic tests to predict and diagnose Alzheimer disease. J Leg Med. 2000, 21 (4): 445-75.

Britschgi M, Wyss-Coray T: Blood protein signature for the early diagnosis of Alzheimer disease. Arch Neurol. 2009, 66 (2): 161-5.

Volicer L, Berman SA, Cipolloni PB, Mandell A: Persistent vegetative state in Alzheimer disease. Does it exist? Arch Neurol. 1997, 54 (11): 1382-4.

Imabayashi E, Saitoh Y, Tsukamoto T, Sakata M, Takano H: Combination of Astrogliosis and Phosphorylated Tau for the Preclinical Diagnosis of Alzheimer Disease Using 3-Dimensional Stereotactic Surface Projection Images With 18 F-THK5351. Clin Nucl Med. 2022, 47 (12): 1066-1068.

Martínez A, Lahiri DK, Giacobini E, Greig NH: Advances in Alzheimer therapy: understanding pharmacological approaches to the disease. Curr Alzheimer Res. 2009, 6 (2): 83-5.

['Kәlanzәma ro cistәgә: liita']

['Websayit adә ilmu matәbe-a bayan matәbe bas nankaro cedo kuru shawari liyitabe au cidawa cidawu liyitabe diobe gәnyi.']

['Bayanwa yitagattәgәna so dә kwasa laa au kwasa laa asutu au kurun dio ro faidatәmba, kuru am doni shawaria liyitaye mazayin so dә dokta lasisatәna ro manatә saadin.']

['Martәne netәram kәrәnbe do korowa dә ro jawawu suwudin dә, taganasmaro kalkal gәnyi sa lamba isәna dәn. Misallo, nәm nguwu am doni kwasa laa taganasbe shiro asuzana ma.']

["Sambi so ro shawari kam litari nәm au kam gade nasha nәlewabe nozәna ma ye la'atar ro matәne. Shawari kam litaribe nozәna ma ro tәmmaro hangal gәnyi gәnane au sha matә lan loktu gozәnyi awo laa website adәn kәrәnәmma yen. Nyiye kurun nәlewabe batәrammin maa, talfon 911 lan buwoze au njim liwalabe karungu ma ro lenәme. Alaka nәlewa-a dondibe ba ma tuwandin web site adә men au shilan faidatәmen. BioMedLib-a cidawunzә-a, au kam do web site adә ro banazәyin-aye, affima bayanzәna au manazәna ma sadimba, bayanwa suro adәben tuwandin au shilan faidatәmen."]

['Kәlanzәma ro cistәgә: hakku']

['Digital Millennium Copyright Act 1998 17 U.S.C. § 512 (DMCA) dəye am doni hakku kakkadə baksanasodəga nzəliwo sədinma kəla awo lardə U.S.be kərma kakkadə baksəna dəga internet lan fəletəma nzəliwo nankaro.']

['Suro nәm kәla nәm ngәla yen awo laa au kare laa kәla intanetndeyen au cidawandeyen mbejiye hakku nәm kakkadi ruotәbe nyiro kalzәna ma ye mbeji maa, nyi (au wakkilnәm) andero watiya zuwune awo au kare dә tutuluwu, au na dәro nazәgә dә tutuluwu.']

["Zande so dә ruwo lan zuzaiya, email men (adәretәm emailye dә nasha 'Lam'atarro manәmin)"]

['DMCA ye məradənzə bayan kəla nzətkawo kərmaabedəbe bayanwa anyi surodən mbejiro: (1) bayan kəla cida nzətkawobe dunonzə dunonzə kaltəgəbe dunonzə kaltəgəbe; (2) bayan kəla awoa zortəbe dunonzə kaltəgəbe dunonzə kuru bayan kəzəkə andeya səkə awoadəga fandəmin; (3) bayan kəlanəm lamba fantəbe, suro nzəranəm-a, lamba telehonbe-a kuru email-be-a; (4) bayan kəlanəmbe kəla nyiye tawatkənənde kəla awoa zortəbe dunonzə kaltəgəbe dunonzəye dunonzəye səkə au wakilinzəye, au shara laabe səkə; ']

['(5) bayan nyima, kalima jirebero, ruwotәgәna, bayan suro watiyade dә kalkalzәna kuru nyiye hakku kәlanzәbe hakkuwa ləbtәma soye warmatәgәbe dәga nonәmma;']

['kuru (6) mukko dunowa au lantarkibe hakkiwa ləbtamabe au kam laaye wakil zəben cida sədənabe. ']

['Bayanna samibe samma kәltәgә nyiye mowonzә zәktә lamar buruwunәmye gәrәmin.']

['Lǝtǝram']

['Martәne ande ro watiya emailye lan koro/shawari laa manane.']

How is alzheimer diagnosed?

Alzheimer's disease is diagnosed through a combination of methods, including a thorough medical evaluation, cognitive and neuropsychological tests, brain imaging, and the process of elimination of other possible causes.

1. Medical evaluation: A doctor will perform a physical examination and take a detailed medical history to rule out other possible causes of memory loss or cognitive decline, such as thyroid problems, vitamin deficiencies, or brain tumors.

2. Cognitive and neuropsychological tests: These tests assess memory, language, problem-solving, and other cognitive functions to determine the extent of cognitive impairment and to differentiate between normal age-related memory loss and dementia.

3. Brain imaging: Magnetic resonance imaging (MRI) or computed tomography (CT) scans can help identify structural changes in the brain that may indicate Alzheimer's disease.

Positron emission tomography (PET) scans can also be used to measure the levels of certain proteins associated with Alzheimer's disease.

4. Blood tests: Recent research has shown that certain blood tests can help diagnose Alzheimer's disease by measuring the levels of specific proteins or biomarkers associated with the disease.

5. Process of elimination: Since there is no single definitive test for Alzheimer's disease, diagnosis often involves ruling out other possible causes of dementia-like symptoms.

It is important to note that a definitive diagnosis of Alzheimer's disease can only be made after death through an examination of brain tissue.

However, current diagnostic methods can provide a high level of certainty for a clinical diagnosis while the person is still alive.

Early diagnosis is important for starting treatment and planning for the future.

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