How is Prostate cancer diagnosed?

['Wande ruwu adǝ fanne']

Jilibi men kwasa kansabe prostatebe notәyin?

Kwasa kansabe prostatebe dә jarabtәwa-a duluwa-a kadan tuwandәna, surodәn:

1. Digital Rectal Exam (DRE): Liyitabe ngulondo rowata, tiyinzǝ lan lubricated sǝkkin suro rectumbe ro prostatebe awo laa kalkal gǝnyi ma fǝlejin nankaro.

2. Prostate-Specific Antigen (PSA) Test: Adә shima bu kulashi do PSA nәm ngәwu fәlezәyin ma, protein doni prostate glandye sәtandin ma.

PSA nǝm nguwu dǝ ye raksǝ kwasa kansa prostatebe fǝlezǝyin.

3. Transrectal Ultrasound (TRUS): Kulashi gana laa rectum ro təkkin foto prostatebe tando nankaro faidatə kowo kowobe men.

Adәye banazәgә awo laa suro prostate glandbe lan wajin ma asutin.

4. Biopsy: Tiyi prostatebe gana laa tutuluyin kuru sha microscope lan kulashiya cells kansabe mbeji la ba ro.

Adәma zawal fal dәma bas kwasa kansa prostatebe asutabe.

5. Magnetic Resonance Imaging (MRI): MRI scanning prostatebe dә ye nәm donyi batti laa mbeji asutin kuru duluwu biopsybe dә suwudin.

6. Kulashi Genomicbe: Liyitawa laabe waneye kulashi genomicbe faidata ngǝlaro asutin nǝmkura kansabedǝ-a kuru futu kurun kǝndobe-a.

7. Bone Scan: Bone scan dәwa dio raktәna cancer dә shila ro tartәgәna wa ro kulastә nankaro.

8. Computed Tomography (CT) Scan: CT scan faidatә kwasa kansabe awawa gade ro tartәgәna wa ro kulastәyin.

Notǝ dǝ zauro mǝradǝtǝna kǝla PSA nyiyanzǝ samiyayen au awo DRE lan notǝna dǝ ngǝlaro waljiya kam so dǝ kwasa kansa prostate be sadinmba, kuru kwasa kansa prostate be samma so PSA nyiyanzǝ samiyayen suwudinmba.

Adǝ nankadǝro, biopsy dǝ mǝradǝtǝna bayan kǝnzǝli dǝga tawattǝgǝro.

Kǝlâ adu ye, shawari kǝla biopsy dio be dǝ tǝdǝna ngawo awoa kulashi anyiye tuwondǝna dǝga kuru tajirwa kam dǝbe-a awo sǝraana dǝga kǝlan kulashi tǝdǝna dǝn.

['Wutəgə']

PubMed/Medline https://www.nlm.nih.gov/databases/download/pubmed_medline.html

RefinedWeb https://arxiv.org/abs/2306.01116

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Marenco J, Kasivisvanathan V, Emberton M: New standards in prostate biopsy. Arch Esp Urol. 2019, 72 (2): 142-149.

Moradi M, Mousavi P, Abolmaesumi P: Computer-aided diagnosis of prostate cancer with emphasis on ultrasound-based approaches: a review. Ultrasound Med Biol. 2007, 33 (7): 1010-28.

Cuperlovic-Culf M, Belacel N, Davey M, Ouellette RJ: Multi-gene biomarker panel for reference free prostate cancer diagnosis: determination and independent validation. Biomarkers. 2010, 15 (8): 693-706.

McGrath SE, Michael A, Morgan R, Pandha H: EN2: a novel prostate cancer biomarker. Biomark Med. 2013, 7 (6): 893-901.

An Y, Chang W, Wang W, Wu H, Pu K, Wu A, Qin Z, Tao Y, Yue Z, Wang P, Wang Z: A novel tetrapeptide fluorescence sensor for early diagnosis of prostate cancer based on imaging Zn2+ in healthy versus cancerous cells. J Adv Res. 2020, 24 (): 363-370.

[Consensus of Chinese experts on the application of molecular imaging targeting prostate specific membrane antigen in prostate cancer patients]. Zhonghua Wai Ke Za Zhi. 2018, 56 (2): 91-94.

Zhong WD, He HC, Bi XC, Ou RB, Jiang SA, Liu LS: cDNA macroarray for analysis of gene expression profiles in prostate cancer. Chin Med J (Engl). 2006, 119 (7): 570-3.

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How is prostate cancer diagnosed?

Prostate cancer is diagnosed through a combination of tests and procedures, which may include:

1. Digital Rectal Exam (DRE): A doctor inserts a gloved, lubricated finger into the rectum to feel the prostate for any abnormalities.

2. Prostate-Specific Antigen (PSA) Test: This is a blood test that measures the level of PSA, a protein produced by the prostate gland.

Elevated PSA levels may indicate the presence of prostate cancer.

3. Transrectal Ultrasound (TRUS): A small probe is inserted into the rectum to create an image of the prostate using sound waves.

This can help identify any abnormalities in the prostate gland.

4. Biopsy: A small sample of prostate tissue is removed and examined under a microscope for the presence of cancer cells.

This is the only definitive way to diagnose prostate cancer.

5. Magnetic Resonance Imaging (MRI): An MRI scan of the prostate can help identify any abnormalities and guide the biopsy procedure.

6. Genomic Testing: Some doctors may use genomic tests to help determine the aggressiveness of the cancer and guide treatment decisions.

7. Bone Scan: A bone scan may be performed to check if the cancer has spread to the bones.

8. Computed Tomography (CT) Scan: A CT scan may be used to check if the cancer has spread to other organs or tissues.

It is important to note that not all men with elevated PSA levels or abnormal DRE results will have prostate cancer, and not all prostate cancers will cause elevated PSA levels.

Therefore, a biopsy is necessary to confirm the diagnosis.

Additionally, the decision to undergo a biopsy is made after considering the results of these tests and the individual's risk factors and preferences.

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