O morbo de Alzheimer o l'é un desordine neurodegenerativo progrescivo ch'o l'affettua prinçipalmente o çervello, caxonando perdia de memöia, declin cognitivo e cangiamenti into comportamento.
A caxon esatta da mouttia de Alzheimer a no l'é ben conosciua, ma se pensa ch'a segge o resultato de unna combinaçion de fattoî genetichi, ambientali e stile de vitta.
Tra i fattoî che peuan contribuî a-o sviluppo da mouttia de Alzheimer gh'é:
1. Genetica: l"é stæto identificou çerti geni che fan cresce o reisego de sviluppâ a mouttia de Alzheimer, in particolâ o gene apolipoproteina E (APOE).
2. Etæ: o reisego de sviluppâ a mouttia de Alzheimer o l'aumenta con l'etæ, e a ciù parte de persoñe vëgnan diagnosticæ dòppo i 65 anni.
3. stöia da famiggia: avei unna stöia de famiggia de mouttia de Alzheimer o peu aumentâ o reisego de sviluppâ a condiçion.
4. Dòppo de lesioin a-a testa: unna stöia de lesioin a-a testa, sorviatutto quelle che causan a perdia do conoscimento, a peu fâ cresce o reisego do morbo de Alzheimer.
5. Fattori de reisego cardiovascolare: de condiçioin comme l'ipertencion, o colesterolo erto e o diabete peuan aumentâ o reisego de sviluppâ a mouttia de Alzheimer.
6. Fattori ligæ a-o stile de vitta: Un stile de vitta sedentäio, unna dieta pövia e a mancansa de stimolo mentale peuan aumentâ o reisego do morbo de Alzheimer.
7. Infiammaçion: unna infiammaçion cronica do çervello a peu contribuî a-o sviluppo do morbo de Alzheimer.
8. stress ossidativo: Un squilibrio tra a produçion de radicali liberi e a capaçitæ do còrpo de desintoxicâli o peu contribuî a-o sviluppo do morbo de Alzheimer.
9. placche amiloidi e groppi neurofibrillari: L'accumulaçion de placche amiloidi e groppi neurofibrillari into çervello a l'é un segno distintivo da mouttia de Alzheimer, ma o seu ròllo into desviluppo da condiçion o no l'é ancon ben compreiso.
L'é importante notâ che a caxon da mouttia de Alzheimer a l'é complessa e probabilmente a coinvòlze unna combinaçion de sti fattoî.
A reçerca a l'é apreuvo à anâ avanti pe capî megio i meccanismi sottostanti e sviluppâ di trattamenti efficaxi pe sta condiçion devastante.
Vellas B, Andrieu S, Cantet C, Dartigues JF, Gauthier S: Long-term changes in ADAS-cog: what is clinically relevant for disease modifying trials in Alzheimer? J Nutr Health Aging. , 11 (4): 338-41.
Braak E, Griffing K, Arai K, Bohl J, Bratzke H, Braak H: Neuropathology of Alzheimer's disease: what is new since A. Alzheimer? Eur Arch Psychiatry Clin Neurosci. 1999, 249 Suppl 3 (): 14-22.
Kovacs GG: Can Creutzfeldt-Jakob disease unravel the mysteries of Alzheimer? Prion. 2016, 10 (5): 369-376.
Cankurtaran M, Yavuz BB, Cankurtaran ES, Halil M, Ulger Z, Ariogul S: Risk factors and type of dementia: vascular or Alzheimer? Arch Gerontol Geriatr. , 47 (1): 25-34.
Mahami-Oskouei M, Hamidi F, Talebi M, Farhoudi M, Taheraghdam AA, Kazemi T, Sadeghi-Bazargani H, Fallah E: Toxoplasmosis and Alzheimer: can Toxoplasma gondii really be introduced as a risk factor in etiology of Alzheimer? Parasitol Res. 2016, 115 (8): 3169-74.
['Disclaimer: medicâ']
["Sto scito web o l'é fornio solo pe di propòxiti educativi e informativi e o no costituisce un conseggio medico ò serviççi profescionæ."]
["L'informaçion fornia a no dovieiva ëse deuviâ pe diagnosticâ ò curâ un problema de sanitæ ò unna mouttia, e quelli che çercan un conseggio medico personale devan consultâ un mego licençiou."]
['Pe piaxei, ti ti o sæ che a ræ neurale ch\'a genera de respòste a-e domande a l"é inprecisa sorviatutto quande se tratta de contegnui numerichi, comme o numero de persoñe che gh\'é stæto diagnosticou unna mouttia particolâ.']
["çercâ delongo o conseggio do teu mego ò de un atro fornitô de sanitæ qualificou in sciâ condiçion medica. no trascurâ mai o conseggio de un mego profescionista ò ritardâ a çercâlo apreuvo à quarcösa che ti t'æ lezuo in sce sto scito web."]
['Disclaimer: copyright']
["O Digital Millennium Copyright Act do 1998, 17 U.S.C. § 512 (o DMCA) o fornisce un ricorso pe-i propietäi de copyright che creddan che o materiale ch'o l'appare in sce Internet o l'infrange i seu driti segondo a leze di copyright di Stati Unii. "]
["Se ti ti creddi de bonn-a fede che un qualunque contegnûo ò materiale misso a dispoxiçion in connescion co-o nòstro scito web ò serviççi o l'infrange i teu driti d'autô, ti (ò o teu agente) ti peu mandâne 'na notifica con domandâ che o contegnûo ò o materiale o segge levòu ò che l'acesso o segge bloccou."]
['E comunicaçioin devan vegnî mandæ pe iscritto pe email (veddi a seçion "Contact" pe l\'indirissô email).']
["O DMCA o l'exige che a teu notifica de presunta violaçion di driti d'autô a contégne e informaçioìn chi sótta: (1) descriçion de l'euvia protetta da driti d'autô ch'a l'é l'oggetto da presunta violaçion; (2) descriçion do contegnûo che se presumibilmente o l'é a violaçion e informaçioìn suffiçienti pe permette a niatri de localizzâlo; (3) informaçioìn de contatto pe ti, compreiso o teu indirìsso, o teu nómme de telefonin e o teu indirìsso email; (4) 'na teu affermaçion che ti ti credi de bonn-a fêde che o contegnûo into mòddo reclamòu o no segge autorizòu da-o propietâio di driti d'autô, ò da-o seu agente, ò da l'açion de quæ se segge leze; "]
["(5) unna declaraçion da parte teu, firmâ sotta pena de perjurio, che e informaçioin inta notifica son accuræ e che ti gh'æ l'autoritæ de fâ respettâ i driti d'autô che se sostegne che seggian stæti violati;"]
["e (6) unna firma fixica ò elettrònica do propietäio do drito d'autô ò de unna persoña autorisâ à agî a-o seu nomme."]
["Se no ti inserisci tutte e informaçioin chì de d'ato, o peu comportâ un retardo into trattamento da teu lamentela."]
['Contatto']
["Pe piaxei manda 'na mail con ògni domanda/suggerimento."]
What causes alzheimer?
Alzheimer's disease is a progressive neurodegenerative disorder that primarily affects the brain, causing memory loss, cognitive decline, and behavioral changes.
The exact cause of Alzheimer's disease is not fully understood, but it is believed to result from a combination of genetic, environmental, and lifestyle factors.
Some of the factors that may contribute to the development of Alzheimer's disease include:
1. Genetics: Certain genes have been identified that increase the risk of developing Alzheimer's disease, particularly the apolipoprotein E (APOE) gene.
2. Age: The risk of developing Alzheimer's disease increases with age, with most people being diagnosed after the age of 65.
3. Family history: Having a family history of Alzheimer's disease may increase the risk of developing the condition.
4. Head injuries: A history of head injuries, particularly those that result in loss of consciousness, may increase the risk of Alzheimer's disease.
5. Cardiovascular risk factors: Conditions such as high blood pressure, high cholesterol, and diabetes may increase the risk of developing Alzheimer's disease.
6. Lifestyle factors: A sedentary lifestyle, poor diet, and lack of mental stimulation may increase the risk of Alzheimer's disease.
7. Inflammation: Chronic inflammation in the brain may contribute to the development of Alzheimer's disease.
8. Oxidative stress: An imbalance between the production of free radicals and the body's ability to detoxify them may contribute to the development of Alzheimer's disease.
9. Amyloid plaques and neurofibrillary tangles: The accumulation of amyloid plaques and neurofibrillary tangles in the brain is a hallmark of Alzheimer's disease, but the role they play in the development of the condition is not fully understood.
It is important to note that the cause of Alzheimer's disease is complex and likely involves a combination of these factors.
Research is ongoing to better understand the underlying mechanisms and develop effective treatments for this devastating condition.
Disclaimer: medical
This web site is provided for educational and informational purposes only and does not constitute providing medical advice or professional services.
The information provided should not be used for diagnosing or treating a health problem or disease, and those seeking personal medical advice should consult with a licensed physician.
Please note the neural net that generates answers to the questions, is specially inaccurate when it comes to numeric content. For example, the number of people diagnosed with a specific disease.
Always seek the advice of your doctor or other qualified health provider regarding a medical condition. Never disregard professional medical advice or delay in seeking it because of something you have read on this website. If you think you may have a medical emergency, call 911 or go to the nearest emergency room immediately. No physician-patient relationship is created by this web site or its use. Neither BioMedLib nor its employees, nor any contributor to this web site, makes any representations, express or implied, with respect to the information provided herein or to its use.
Disclaimer: copyright
The Digital Millennium Copyright Act of 1998, 17 U.S.C. § 512 (the “DMCA”) provides recourse for copyright owners who believe that material appearing on the Internet infringes their rights under U.S. copyright law. If you believe in good faith that any content or material made available in connection with our website or services infringes your copyright, you (or your agent) may send us a notice requesting that the content or material be removed, or access to it blocked. Notices must be sent in writing by email (see 'Contact' section for email address) . The DMCA requires that your notice of alleged copyright infringement include the following information: (1) description of the copyrighted work that is the subject of claimed infringement; (2) description of the alleged infringing content and information sufficient to permit us to locate the content; (3) contact information for you, including your address, telephone number and email address; (4) a statement by you that you have a good faith belief that the content in the manner complained of is not authorized by the copyright owner, or its agent, or by the operation of any law; (5) a statement by you, signed under penalty of perjury, that the information in the notification is accurate and that you have the authority to enforce the copyrights that are claimed to be infringed; and (6) a physical or electronic signature of the copyright owner or a person authorized to act on the copyright owner’s behalf. Failure to include all of the above information may result in the delay of the processing of your complaint.
['In sciâ']
['BioMedLib o deuvia di computer automatizzæ (algoritmi de machine learning) pe generâ de cobbie de domande e respòste.']
['Comensemmo con 35 mioin de pubricaçioin biomediche de PubMed/Medline.']
