How is Alzheimer diagnosed?

['Klausieties itū lopu']

Kai teik diagnosticāta Alcheimera slimeiba?

Alcheimera slimeiba teik diagnosticāta, izmontojūt vairuokys metodis, tymā skaitā ryupeigu mediciniskū izpieti, kognitivūs i neiropsihologiskūs testus, smedziņu attāluošonu i cytu īspiejamūs cālūņu nūvieršonu.

1. Medicinisks puorbaudejums: uorsts veiks fizisku puorbaudi i ryupeigi izzynuos veseleibys stuovūkli, kab nūsaceitu cytys īspiejamys atmiņu zuduma voi kognitivūs funkceju sasamazynuošonys īmeslis, par pīmāru, vairūgdzīdzieja problemys, vitaminu tryukums voi smedziņu audzieji.

2. kognitivī i neiropsihologiskī testi: itī testi nūviertej atmiņu, volūdu, problemu rysynuošonu i cytys kognitivys funkcejis, kab nūsaceitu kognitivūs trauciejumu apjūmu i atškiertu vacuma īmesļa atmiņu zaudiešonu nu demencejis.

Smedziņu attāluošona: magnetiskuo rezonanse (MRI) voi datorizātuo tomografeja (CT) var paleidzēt nūsaceit strukturaluos izmainis smedzīnī, kas var līkuotīs par Alcheimera slimeibu.

Pozitronu emisejis tomografejis (PET) skeniešonu var izmontuot, kab miereitu nūteiktu Alcheimera slimeibu izraisejūšu proteinu leimini.

4. Asins puorbaudis: naseņ veiktī pietejumi ir paruodejuši, ka nūsaceitys asins puorbaudis var paleidzēt diagnosticēt Alcheimera slimeibu, mierejūt ar slimeibu saisteitu specifisku proteinu voi biomarkeru leimini.

5. Eliminacejis process: Tai kai nav vīnys nūteiktys Alcheimera slimeibys analizis, diagnoze bīži īkļaun atmest cytys īspiejamys demencejis slimeibu simptomu cālūnis.

Ir svareigi atzeimuot, ka Alcheimera slimeibys definitivū diagnozi var izdareit tik piec nuovis, pietejūt smedziņu audu.

Tok pošreizejī diagnostikys pajiemīni var nūdrūsynuot augstu kliniskuo diagnozis drūšeibys leimini, cikom persona vēļ ir dzeiva.

Seneja diagnoze ir svareiga, kab suoktu dzīdynuošonu i plānuot sovu nuokūtni.

['Nūruodis']

PubMed/Medline https://www.nlm.nih.gov/databases/download/pubmed_medline.html

RefinedWeb https://arxiv.org/abs/2306.01116

Liu SS, Zhu SQ: [Correlation between Alzheimer disease and cataract]. Zhonghua Yan Ke Za Zhi. 2017, 53 (4): 314-316.

Gauthier S: Practical guidelines for the antemortem diagnosis of senile dementia of the Alzheimer type. Prog Neuropsychopharmacol Biol Psychiatry. 1985, 9 (5-6): 491-5.

Rubin R: New Test to Help Diagnose Alzheimer Disease. JAMA. 2022, 327 (23): 2281.

[Blood Based Biomarker for Optimization of Early and Differential Diagnosis of Alzheimer's Dementia]. Fortschr Neurol Psychiatr. 2022, 90 (7-08): 326-335.

Kapp MB: Physicians' legal duties regarding the use of genetic tests to predict and diagnose Alzheimer disease. J Leg Med. 2000, 21 (4): 445-75.

Britschgi M, Wyss-Coray T: Blood protein signature for the early diagnosis of Alzheimer disease. Arch Neurol. 2009, 66 (2): 161-5.

Volicer L, Berman SA, Cipolloni PB, Mandell A: Persistent vegetative state in Alzheimer disease. Does it exist? Arch Neurol. 1997, 54 (11): 1382-4.

Imabayashi E, Saitoh Y, Tsukamoto T, Sakata M, Takano H: Combination of Astrogliosis and Phosphorylated Tau for the Preclinical Diagnosis of Alzheimer Disease Using 3-Dimensional Stereotactic Surface Projection Images With 18 F-THK5351. Clin Nucl Med. 2022, 47 (12): 1066-1068.

Martínez A, Lahiri DK, Giacobini E, Greig NH: Advances in Alzheimer therapy: understanding pharmacological approaches to the disease. Curr Alzheimer Res. 2009, 6 (2): 83-5.

['Atsaceišona nu: medicinys']

['Itei interneta vītne ir dūmuota tikai izgleiteibys i informacejis īmeslim, i tei nateik skaiteita par medicinys pīduovuojumu voi profesionalu pakolpuojumu.']

['Pīduovuotū informaceju nadreikst lītuot, kab diagnosticātu voi izuorstātu kaidu slimeibu, i tim, kas meklej personeigu mediciniskū padūmu, juosazynoj ar licencātu uorstu.']

['Juopīzeist, ka neironu teikls, kas generej atbiļdis iz vaicuojumim, ir eipaši napareizs, kod runoj par skaitliskū saturu, par pīmāru, par konkretu slimeibu diagnozātūs cylvāku skaitu.']

['Vysod meklejit padumu nu sova uorsta voi cyta kvalificāta uorsta, kab saprostu jiusu slimeibu. Nikod naatsakuortojit profesionalū uorsta padumu voi aizkavejit tū mekliešonu deļtuo, ka esat koč kū izlasiejs itamā interneta vītnē. Ka jiusim ruodīs, ka jiusim var byut uorsteibys uorkuortys situaceja, zvaniet 911 voi īīt tyvuokajā uorstnīceibys centrā.']

['Atsaceišona: autortiesības']

['1998. goda Digitaluo tyukstūšgadis autoru tīseibu lykums, 17 U.S.C. § 512 (DMCA) nūdrūsynoj tīseibu aizstuoviešonu autoru tīseibu turātuojim, kuri skaita, ka materialā, kas pasaruoda iz škārsteikla, ir puorkuoptys jūs tīseibys saskaņā ar ASV autoru tīseibu lykumim. ']

['Ka jius iz lobu tycat, ka kaids saturs voi materials, kas ir pīejams saisteibā ar myusu sātom voi pakolpuojumim, puorkuop jiusu autortiesības, jius (voi jiusu aģents) jiusim var syuteit paziņuojumu, kurā lyugts svīgt itū saturu voi materialu voi bloķēt pīeju tam.']

['Paziņuojumi ir juonūsyuta e-postā (vērtīs sadaļu "Kontakti" e-posta adresei).']

['DMCA prasej, kab jiusu paziņuojumā par īspiejamu autortiesību puorkuopumu byutu īkļauta itei informaceja: (1) ar autortiesībām aizsorguotuo dorba aproksts, kas ir īspiejamuos puorkuopuma objekts; (2) īspiejamuos puorkuopuma satura aproksts i informaceja, kas ir pīteikama, kab ļautu mums atrast saturu; (3) jiusu kontaktinformaceja, tymā skaitā adrese, telefona numurs i e-posta adrese; (4) apstyprynuojums, ka jius asat puorlīcynuots, ka saturs tai, kai ir ībyldts, nav atļauts ar autortiesību eipašnīka voi juo aģenta voi kaida lykuma atbolstu; ']

['5. aplīcynuojumu, ka jiusu informaceja ir pareiza i ka jiusim ir tīseibys izmontuot autortīseibys, kuruos ir nūlīgts lītuot;']

['i 6) fizisks voi elektronisks autortīseibu turātuoja voi personas, kas ir pilnvarota dorbuotīs autortīseibu turātuoja vuordā, paraksts.']

['Ka naatsaroksta vysa īprīkš mynātuo informaceja, var nūtikt kavējums tovu škieršonūs.']

['Kontakti ar mums']

['Lyudzu, syutiet mums e-postu ar sevkuru vaicuojumu/ieteikumu.']

How is alzheimer diagnosed?

Alzheimer's disease is diagnosed through a combination of methods, including a thorough medical evaluation, cognitive and neuropsychological tests, brain imaging, and the process of elimination of other possible causes.

1. Medical evaluation: A doctor will perform a physical examination and take a detailed medical history to rule out other possible causes of memory loss or cognitive decline, such as thyroid problems, vitamin deficiencies, or brain tumors.

2. Cognitive and neuropsychological tests: These tests assess memory, language, problem-solving, and other cognitive functions to determine the extent of cognitive impairment and to differentiate between normal age-related memory loss and dementia.

3. Brain imaging: Magnetic resonance imaging (MRI) or computed tomography (CT) scans can help identify structural changes in the brain that may indicate Alzheimer's disease.

Positron emission tomography (PET) scans can also be used to measure the levels of certain proteins associated with Alzheimer's disease.

4. Blood tests: Recent research has shown that certain blood tests can help diagnose Alzheimer's disease by measuring the levels of specific proteins or biomarkers associated with the disease.

5. Process of elimination: Since there is no single definitive test for Alzheimer's disease, diagnosis often involves ruling out other possible causes of dementia-like symptoms.

It is important to note that a definitive diagnosis of Alzheimer's disease can only be made after death through an examination of brain tissue.

However, current diagnostic methods can provide a high level of certainty for a clinical diagnosis while the person is still alive.

Early diagnosis is important for starting treatment and planning for the future.

Disclaimer: medical

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Please note the neural net that generates answers to the questions, is specially inaccurate when it comes to numeric content. For example, the number of people diagnosed with a specific disease.

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