Urticaria, amanyiddwa nga hives, y'ekirwadde ky'olususu ekireetebwa n'ebiwundu ebinyuma ebiyinza okulabika ku kitundu kyonna eky'omubiri.
Kiyinza okuleetebwa ebintu eby'enjawulo, nga mw'otwalidde endwadde, endwadde, oba obulwadde obulala.
Obujjanjabi bw'obulwadde bwa urticaria bwesigamye ku bukambwe bw'obulwadde n'ekiviirako.
Wano waliwo engeri ez'enjawulo ez'okujjanjaba:
1. Antihistamines: Eddagala lino liyamba okukendeeza ku bulumi n'okwegulumiza ng'eziyiza histamine, eddagala eriva mu mubiri mu kiseera ky'obulwadde bw'omubiri.
Eddagala lya over-the-counter antihistamines nga diphenhydramine (Benadryl) oba loratadine (Claritin) liyinza okuba ery'omugaso mu mbeera entono.
Mu mbeera enzibu ennyo, omusawo ayinza okuwa eddagala erirwanyisa akawuka ka antihistamine.
2. Corticosteroids: Mu mbeera ng'eddagala lya antihistamines teririna mugaso, corticosteroids nga prednisone eyinza okuweebwa okukendeeza ku bulwadde n'okuziyiza enkola y'omubiri.
Eddagala lino litera okutwalibwa mu kamwa era lisobola okuwonya omuntu amangu.
3. Immunosuppressants: Mu mbeera za chronic urticaria ezitalina ky'ekola ku bujjanjabi obulala, eddagala eriziyiza obwongo nga cyclosporine oba methotrexate liyinza okuweebwa okukendeeza ku mbeera y'omubiri n'okukendeeza ku bulwadde.
Omalizumab: Eddagala lino ly'ekika kya monoclonal antibody ekiyinza okuteekebwa mu ddagala erirwanyisa era eriziyiza immunoglobulin E (IgE), protein ekola mu mbeera z'obulwadde bw'ensiri.
Kitera okukozesebwa ku urticaria ey'olubeerera etannaba kuddamu bujjanjabi obulala.
Deleanu D, Nedelea I, Petricau C, Leru P, Dumitrascu D, Muntean A: Clinical impact of omalizumab in refractory chronic urticaria: One centre experience. Exp Ther Med. 2019, 18 (6): 5078-5081.
Grundmann SA, Kiefer S, Luger TA, Brehler R: Delayed pressure urticaria - dapsone heading for first-line therapy? J Dtsch Dermatol Ges. 2011, 9 (11): 908-12.
Staumont-Sallé D, Piette F, Delaporte E: [Etiological diagnosis and treatment of chronic urticaria]. Rev Med Interne. 2003, 24 (1): 34-44.
Akashi R, Ishiguro N, Shimizu S, Kawashima M: Clinical study of the relationship between Helicobacter pylori and chronic urticaria and prurigo chronica multiformis: effectiveness of eradication therapy for Helicobacter pylori. J Dermatol. 2011, 38 (8): 761-6.
Calogiuri G, Nettis E, Mandurino-Mirizzi A, Di Leo E, Macchia L, Foti C, Vacca A, Kounis NG: Omalizumab for the Treatment of Persistent Drug Induced Urticaria Elicited by Thienopyridines: A Case Report. Antiinflamm Antiallergy Agents Med Chem. 2020, 19 (3): 335-339.
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Urticaria, commonly known as hives, is a skin condition characterized by itchy, raised welts that can appear on any part of the body.
It can be caused by various factors, including allergic reactions, infections, or underlying medical conditions.
Treatment for urticaria depends on the severity of the condition and the underlying cause.
Here are some common treatment options:
1. Antihistamines: These medications help to reduce itching and swelling by blocking the effects of histamine, a chemical released by the body during an allergic reaction.
Over-the-counter antihistamines such as diphenhydramine (Benadryl) or loratadine (Claritin) can be effective in mild cases.
In more severe cases, a doctor may prescribe stronger antihistamines.
2. Corticosteroids: In cases where antihistamines are not effective, corticosteroids such as prednisone may be prescribed to reduce inflammation and suppress the immune system.
These medications are usually taken orally and can provide quick relief.
3. Immunosuppressants: In cases of chronic urticaria that do not respond to other treatments, immunosuppressant drugs such as cyclosporine or methotrexate may be prescribed to suppress the immune system and reduce inflammation.
4. Omalizumab: This medication is an injectable monoclonal antibody that targets and blocks immunoglobulin E (IgE), a protein involved in allergic reactions.
It is typically used for chronic urticaria that does not respond to other treatments.
5. Avoid triggers: Identifying and avoiding triggers that cause urticaria can help prevent outbreaks.
Common triggers include certain foods, medications, insect bites, and exposure to heat, cold, or sunlight.
6. Cold compress: Applying a cold compress to the affected area can help reduce itching and swelling.
7. Wet wraps: Wet wraps can be used to soothe itching and reduce inflammation.
A damp cloth is wrapped around the affected area, and then a dry cloth is placed over it to retain moisture.
8. Phototherapy: Exposure to ultraviolet light can help suppress the immune system and reduce inflammation in some cases of chronic urticaria.
It is important to consult a healthcare professional for proper diagnosis and treatment of urticaria.
They can help determine the underlying cause and recommend the most appropriate treatment plan.
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