What is pathophysiology of Depression?

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Kiko ta fisiopatologia di depreshon?

E fisiopatologia di depresion ta referi na e estudio di e proceso of mekanismo fisiologico desordená ku ta responsabel pa desaroyo i progreso di depresion.

E ta enserá komprondé e faktornan biológiko, neurológiko i sikológiko ku ta kontribuí na e komienso i persistensia di síntoma di depreshon.

Investigadónan a identifiká diferente kousa i mekanismo ku por kontribuí na depreshon, inkluyendo faktornan genétiko, kambionan den nivel i aktividat di neurotransmisor, kambionan den struktura i funshon di serebro i faktornan di strès ambiental.

E fisiopatologia di depresion ta kompleho i multifacétiko, i ta probabel ku un kombinashon di e faktornan aki ta kontribuí na desaroyo di e malesa den diferente persona.

['Referensia']

PubMed/Medline https://www.nlm.nih.gov/databases/download/pubmed_medline.html

RefinedWeb https://arxiv.org/abs/2306.01116

Lai CH: The neural markers of MRI to differentiate depression and panic disorder. Prog Neuropsychopharmacol Biol Psychiatry. 2019, 91 (): 72-78.

Robinson RG, Chemerinski E, Jorge R: Pathophysiology of secondary depressions in the elderly. J Geriatr Psychiatry Neurol. 1999, 12 (3): 128-36.

Krishnan KR, McDonald WM, Doraiswamy PM, Tupler LA, Husain M, Boyko OB, Figiel GS, Ellinwood EH: Neuroanatomical substrates of depression in the elderly. Eur Arch Psychiatry Clin Neurosci. 1993, 243 (1): 41-6.

Olsen TS: Pathophysiology of the migraine aura: the spreading depression theory. Brain. 1995, 118 ( Pt 1) (): 307-8.

Normann C: Towards a new model for cellular pathophysiology in affective disorder. Acta Neuropsychiatr. 2000, 12 (3): 77-80.

Adler UC, Marques AH, Calil HM: Inflammatory aspects of depression. Inflamm Allergy Drug Targets. 2008, 7 (1): 19-23.

Rihmer Z, Seregi K, Rihmer A: Parkinson's disease and depression. Neuropsychopharmacol Hung. 2004, 6 (2): 82-5.

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What is pathophysiology of depression?

Pathophysiology of depression refers to the study of the disordered physiological processes or mechanisms that are responsible for the development and progression of depression.

It involves understanding the underlying biological, neurological, and psychological factors that contribute to the onset and persistence of depressive symptoms.

Researchers have identified several potential causes and mechanisms that may contribute to depression, including genetic factors, alterations in neurotransmitter levels and activity, changes in brain structure and function, and environmental stressors.

The pathophysiology of depression is complex and multifaceted, and it is likely that a combination of these factors contributes to the development of the disorder in different individuals.

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