What causes Alzheimer?

Dhageyso boggan

Maxaa keena cudurka Alzheimers?

Cudurka Alzheimers waa cudur neerfaha oo sii kordhaya oo inta badan saameeya maskaxda, taasoo keenta xusuusta oo hoos u dhacda, garashada oo hoos u dhacda, iyo isbedelka dabeecadda.

Sababta saxda ah ee cudurka Alzheimers si buuxda looma fahmin, laakiin waxaa la rumeysan yahay inuu ka dhasho isku darka hiddo-wadaha, deegaanka, iyo qaab nololeedka.

Qaar ka mid ah waxyaabaha keeni kara cudurka Alzheimer waxaa ka mid ah:

1. hiddo-wadaha: Waxaa la ogaaday in hiddo-wadaha qaarkood ay kordhiyaan halista cudurka Alzheimers, gaar ahaan hiddo-wadaha apolipoprotein E (APOE).

2. Da'da: Khatarta cudurka Alzheimers waxay kordheysaa da'da, dadka badankoodna waxaa la ogaadaa da'da 65 jirka ka dib.

3. Taariikhda qoyska: Taariikhda qoyska ee cudurka Alzheimers waxay kordhin kartaa khatarta ah in cudurka uu ku dhaco.

4. Dhaawacyada madaxa: Dhaawacyada madaxa, gaar ahaan kuwa keena miyir la'aanta, waxay kordhin karaan halista cudurka Alzheimer.

5. Waxyaabaha halista ku ah wadnaha iyo xididdada dhiigga: Xaaladaha sida cadaadiska dhiigga oo sarreeya, kolestaroolka oo sarreeya, iyo sonkorowga ayaa kordhin kara khatarta cudurka Alzheimer.

6. Qaab nololeedka: Qaab nololeed fadhiid ah, cunto aan fiicnayn, iyo dhiirigelin la'aan maskaxeed ayaa kordhin kara khatarta cudurka Alzheimer.

7. Caabuqa: Caabuqa joogtada ah ee maskaxda wuxuu gacan ka geysan karaa horumarinta cudurka Alzheimers.

8. Cadaadiska oksaydhka: Isku dheelitir la'aanta u dhaxaysa soo saarista xagjirka xorta ah iyo awooda jidhka ee ka saarista sunta waxay gacan ka geysan kartaa horumarinta cudurka Alzheimer.

9. Amyloid plaques iyo neurofibrillary tangles: Ururinta amyloid plaques iyo neurofibrillary tangles ee maskaxda waa astaanta cudurka Alzheimer, laakiin doorka ay ka ciyaaraan horumarinta xaaladda si buuxda looma fahmin.

Waxaa muhiim ah in la ogaado in sababta cudurka Alzheimers ay tahay mid adag oo ay u badan tahay inay ku lug leedahay isku darka arrimahan.

Cilmi baaris ayaa socota si loo fahmo hababka aasaasiga ah loona horumariyo daaweyn wax ku ool ah oo loogu talagalay xaaladdan ba'an.

Tixraacyada

PubMed/Medline https://www.nlm.nih.gov/databases/download/pubmed_medline.html

RefinedWeb https://arxiv.org/abs/2306.01116

Vellas B, Andrieu S, Cantet C, Dartigues JF, Gauthier S: Long-term changes in ADAS-cog: what is clinically relevant for disease modifying trials in Alzheimer? J Nutr Health Aging. , 11 (4): 338-41.

Braak E, Griffing K, Arai K, Bohl J, Bratzke H, Braak H: Neuropathology of Alzheimer's disease: what is new since A. Alzheimer? Eur Arch Psychiatry Clin Neurosci. 1999, 249 Suppl 3 (): 14-22.

Kovacs GG: Can Creutzfeldt-Jakob disease unravel the mysteries of Alzheimer? Prion. 2016, 10 (5): 369-376.

Cankurtaran M, Yavuz BB, Cankurtaran ES, Halil M, Ulger Z, Ariogul S: Risk factors and type of dementia: vascular or Alzheimer? Arch Gerontol Geriatr. , 47 (1): 25-34.

Mahami-Oskouei M, Hamidi F, Talebi M, Farhoudi M, Taheraghdam AA, Kazemi T, Sadeghi-Bazargani H, Fallah E: Toxoplasmosis and Alzheimer: can Toxoplasma gondii really be introduced as a risk factor in etiology of Alzheimer? Parasitol Res. 2016, 115 (8): 3169-74.

Diidmada masuuliyada: caafimaadka

Boggan waxaa loogu talagalay ujeedooyin waxbarasho iyo macluumaad oo keliya mana aha bixinta talo caafimaad ama adeegyo xirfadeed.

Macluumaadka la bixiyo waa in aan loo isticmaalin in lagu ogaado ama lagu daweeyo dhibaato caafimaad ama cudur, kuwa raadinaya talo caafimaad oo shaqsiyeed waa inay la tashadaan dhakhtar ruqsad haysta.

Fadlan la soco in shabakada neerfaha ee soo saarta jawaabaha su'aalaha, ay tahay mid aan sax ahayn marka ay timaado waxyaabaha tirooyinka ah. Tusaale ahaan, tirada dadka la ogaaday inay qabaan cudur gaar ah.

Had iyo jeer raadi talada dhakhtarkaaga ama daryeel caafimaad oo kale oo u qalma oo ku saabsan xaalad caafimaad. Waligaa ha iska indho tirin talada caafimaadka xirfadeed ama ha dib u dhigin raadinta sababtoo ah wax aad ka akhrisay boggan internetka. Haddii aad u maleyneyso inaad leedahay xaalad caafimaad oo degdeg ah, wac 911 ama u tag qolka gurmadka degdegga ah ee kuugu dhow isla markiiba. Xiriirka dhakhtarka iyo bukaanka looma abuuro boggan internetka ama isticmaalkiisa. BioMedLib ama shaqaalaheeda, ama qof kasta oo ka qaybqaata boggan internetka, ma sameeyaan wax matalaad ah, si cad ama si macquul ah, oo ku saabsan macluumaadka halkan lagu bixiyo ama isticmaalkiisa.

Ogaysiiska: Xuquuqda daabacaadda

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Ogeysiisyada waa in lagu diraa qoraal ahaan emayl (eeg qaybta "Contact" ee cinwaanka emaylka).

DMCA waxay u baahan tahay in ogeysiiskaaga ku saabsan xadgudubka xuquuqda daabacaadda ee la sheegay uu ku jiro macluumaadka soo socda: (1) sharaxaadda shaqada xuquuqda daabacaadda ee ay ku saabsan tahay xadgudubka la sheegay; (2) sharaxaadda nuxurka xadgudubka la sheegay iyo macluumaadka ku filan ee noo oggolaanaya inaan helno nuxurka; (3) macluumaadkaaga xiriirka adiga, oo ay ku jiraan cinwaankaaga, lambarka taleefanka iyo cinwaanka emaylkaaga; (4) bayaan aad ku leedahay aaminaad wanaagsan oo ah in nuxurka habka lagu cabiray uusan oggolaan milkiilaha xuquuqda daabacaadda, ama wakiilkiisa, ama hawlgalka sharci kasta;

(5) bayaan aad saxiixday oo aad ku cadeyneyso in macluumaadka ku jira ogeysiiska uu sax yahay iyo in aad awood u leedahay in aad dhaqan geliso xuquuqda daabacaadda ee la sheeganayo in la jabiyay;

iyo (6) saxiix jireed ama elektaroonig ah oo ka yimid milkiilaha xuquuqda daabacaadda ama qof loo oggol yahay inuu ku dhaqmo magaca milkiilaha xuquuqda daabacaadda.

Haddii aadan ku darin dhammaan macluumaadka kor ku xusan waxay keeni kartaa dib u dhac ku yimaada ka baaraandegista cabashadaada.

Xiriirka

Fadlan noogu soo dir emayl su'aal kasta / soo jeedin.

What causes alzheimer?

Alzheimer's disease is a progressive neurodegenerative disorder that primarily affects the brain, causing memory loss, cognitive decline, and behavioral changes.

The exact cause of Alzheimer's disease is not fully understood, but it is believed to result from a combination of genetic, environmental, and lifestyle factors.

Some of the factors that may contribute to the development of Alzheimer's disease include:

1. Genetics: Certain genes have been identified that increase the risk of developing Alzheimer's disease, particularly the apolipoprotein E (APOE) gene.

2. Age: The risk of developing Alzheimer's disease increases with age, with most people being diagnosed after the age of 65.

3. Family history: Having a family history of Alzheimer's disease may increase the risk of developing the condition.

4. Head injuries: A history of head injuries, particularly those that result in loss of consciousness, may increase the risk of Alzheimer's disease.

5. Cardiovascular risk factors: Conditions such as high blood pressure, high cholesterol, and diabetes may increase the risk of developing Alzheimer's disease.

6. Lifestyle factors: A sedentary lifestyle, poor diet, and lack of mental stimulation may increase the risk of Alzheimer's disease.

7. Inflammation: Chronic inflammation in the brain may contribute to the development of Alzheimer's disease.

8. Oxidative stress: An imbalance between the production of free radicals and the body's ability to detoxify them may contribute to the development of Alzheimer's disease.

9. Amyloid plaques and neurofibrillary tangles: The accumulation of amyloid plaques and neurofibrillary tangles in the brain is a hallmark of Alzheimer's disease, but the role they play in the development of the condition is not fully understood.

It is important to note that the cause of Alzheimer's disease is complex and likely involves a combination of these factors.

Research is ongoing to better understand the underlying mechanisms and develop effective treatments for this devastating condition.

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