What causes Alzheimer?

Awa eway Alzheimer?

Aṭṭanen n Alzheimer eqqal aśuhu n neurodegenerative wa iknanen daɣ akayad, eway id aśuhu n asmekti, aśuhu n musnat d imutiyan n alxal

Albab n Alzheimer war itwassan hullan mucham ijja awen ijja awen ijja awen eqqal fal asuj n etari, ahinzazaɣ d immik n tamudre

Iyad haratan addoben ad aruwan efes n Alzheimer eha:

1. Genetics: Gen tan iyyad aqqalan atiwazayan as issiwaden azruf n Alzheimer, hullan apolipoprotein E (APOE) gene

2. Age: Assahat n Alzheimer itaj s tiw-at, addinat ajjotnen tijjach nat s Alzheimer darat awatay wan 65

3. Assahat n tawset: Assahat n tawset n Alzheimer addobat ad issiwid aharoj n aṭṭan

4. Iɣasan n eɣaf: Aqqal n eɣasan n eɣaf daɣ attarex hullan wi id eway nen asuj n musnat addobat ad issiwid aharoj n aṭṭan wan Alzheimer

5. Timkarawen n ahinzazaɣ n aśahat n anifham: Timkarawen chund tanaya tan ajjotnen, cholesterol ajjotnen, d aśahat n aśahat addoben ad awin ahinzazaɣ n aśahat wan Alzheimer

6. Timkarawen n tamudre: Tamudre n asuj, dumu war n ila almaɣna d iban n asuj n akayad addobat ad issiwid aharoj n Alzheimer

7. Inflammation: Inflammation tan ajjotnen daɣ eɣaf addobat ad eway id Alzheimer

8 Oxidative stress: Awar n aharoj jir efes n free radicals d assahat n taɣissa n asuj n isuj win asuj addobat ad eway id efes n aṭṭan wan Alzheimer

9. Amyloid plaques d neurofibrillary tangles: Asidu n amyloid plaques d neurofibrillary tangles daɣ eɣaf eqqal samalan n Alzheimer disease mucham alxidmat nasan daɣ efes n talɣa war t afham hullan

Eqal assohen ad akayad as eɣaf n Alzheimer eqqal a ojjaran tolas ahanat as ijjuch n haratan win

Umaɣ eqqal a fal ikna afham n tikarsiwen n aru d efes n asafar n aśahat wen

['Isalan wi illanen']

PubMed/Medline https://www.nlm.nih.gov/databases/download/pubmed_medline.html

RefinedWeb https://arxiv.org/abs/2306.01116

Vellas B, Andrieu S, Cantet C, Dartigues JF, Gauthier S: Long-term changes in ADAS-cog: what is clinically relevant for disease modifying trials in Alzheimer? J Nutr Health Aging. , 11 (4): 338-41.

Braak E, Griffing K, Arai K, Bohl J, Bratzke H, Braak H: Neuropathology of Alzheimer's disease: what is new since A. Alzheimer? Eur Arch Psychiatry Clin Neurosci. 1999, 249 Suppl 3 (): 14-22.

Kovacs GG: Can Creutzfeldt-Jakob disease unravel the mysteries of Alzheimer? Prion. 2016, 10 (5): 369-376.

Cankurtaran M, Yavuz BB, Cankurtaran ES, Halil M, Ulger Z, Ariogul S: Risk factors and type of dementia: vascular or Alzheimer? Arch Gerontol Geriatr. , 47 (1): 25-34.

Mahami-Oskouei M, Hamidi F, Talebi M, Farhoudi M, Taheraghdam AA, Kazemi T, Sadeghi-Bazargani H, Fallah E: Toxoplasmosis and Alzheimer: can Toxoplasma gondii really be introduced as a risk factor in etiology of Alzheimer? Parasitol Res. 2016, 115 (8): 3169-74.

['Asukni: medikal']

['Web site wen eqqal i isalan n teɣare d isalan ɣas tolas war eqqel asiwil n asafar meɣ alxidmat tan n musnat']

['Isalan wi ikfan war addoben ad axdaman i asifham meɣ asafar n aśahat meɣ aśahat tolas wi aramanen asiwil n asafar n awadim ilzam ad aruman asiwil n asafar n awadim']

['Dǎɣ asikin, neural net wa iknanen tirmawen ən assestan, eqal aśohen aśohat dǎɣ alwaq wa id itawan dǎɣ maɗin ən maɗinan. sund, iddikud ən adinat wi atiwasananen as aśohat atiwasanan.']

['Harkuk arha majrad n doctor inek meɣ n awadim n assexat n tazmert n addinat fal aśahat n aśahat. War t-id-t-igdel majrad n aśahat n awadim meɣ azzaman daɣ aśahat fal as harat awa iktabem fal site wen. Afal as ad t-illa aśahat n aśahat n aśahat, asiwel 911 meɣ aru s ehan n aśahat n aśahat wa oharnen daɣ azzaman. War t-illa majrad n aśahat n awadim d aśahat fal site wen meɣ axadam net. BioMedLib meɣ inaxdiman net meɣ awadim wa iknanen fal site wen, war t-illa majrad, iknan meɣ iknan, fal isalan wi dawanen meɣ axadam net']

['Asukni: copyright']

['Digital Millennium Copyright Act wan 1998, 17 U.S.C. § 512 (DMCA) eha almaɣna i kel alxaq n alxaq n alxaq wa allaɣen as isuj win illanen fal Internet ikna alxaq nasan daɣ achareɣa n alxaq wan alxaq wan alxaq wan alxaq wan alxaq wan alxaq wan alxaq wan alxaq wan alxaq wan alxaq wan alxaq wan alxaq wan alxaq wan alxaq wan alxaq wan alxaq wan alxaq wan alxaq wan alxaq wan alxaq wan alxaq wan alxaq wan alxaq wan alxaq wan alxaq wan alxaq wan alxaq wan alxaq wan alxaq wan alxaq wan alxaq wan alxaq wan alxaq wan alxaq wan alxaq wan alxaq']

['A fal tazamt s tiditt as isalan meɣ isuj win illanen daɣ asuj n asuj net meɣ alxidmaten iknan alxaq inek n alxaq, addobat ad aɣ-d-tazneḍ (meɣ agent inek) isalan meɣ isuj win ad n-ikkes meɣ ad n-isikkid alxidmat']

['Isalan ilzam ad ittusiknan s eɣaf s email (ikayad edag "Contact" i tansa n email)']

['DMCA t-assirɣas as isalan inek n asiwad n alxaq n alxoriya eha isalan win: (1) almaɣna n alxidmat eha alxaq n alxoriya eqqal harat n asiwad eha alxaq n alxoriya; (2) almaɣna n almaɣna eha alxoriya d isalan ajjotnen ijjan aɣ ad n afhaman almaɣna; (3) isalan n alɣisab inek, ahan tansa, amaṭṭaf n tilifun d tansa n email inek; (4) almaɣna inek n as ilan tumast n alxaq n alxoriya as almaɣna wa s eha alxaq eha alxaq eha alxaq war eha alxaq n alxaq eha alxoriya meɣ amatikki net meɣ s alxidmat n achareɣa fuk']

['(5) almaɣna n awen, iktab daɣ azruf n alkad n tiditt, as isalan win isalan aqqalan tiditt tolas ilan tanaya n as artay alxaqqan win alxakum wi s allaɣen as ikna']

['Dǎɣ awa, əmik ən əmik ən alxaq meɣ awadim ən alxaq ən alxaq meɣ awadim atiwafan ye igi ən alxaq ən alxaq.']

['A fal war t-id-t-id-t-id-t-id-t-id-t-id-t-id-t-id-t-id-t-id-t-id-t-id-t-id-t-id-t-id-t-id-t-id-t-id-t-id-t-id-t-id']

['Assahat']

['Ilzam aɣ e-mail s asteqsi meɣ asukni']

What causes alzheimer?

Alzheimer's disease is a progressive neurodegenerative disorder that primarily affects the brain, causing memory loss, cognitive decline, and behavioral changes.

The exact cause of Alzheimer's disease is not fully understood, but it is believed to result from a combination of genetic, environmental, and lifestyle factors.

Some of the factors that may contribute to the development of Alzheimer's disease include:

1. Genetics: Certain genes have been identified that increase the risk of developing Alzheimer's disease, particularly the apolipoprotein E (APOE) gene.

2. Age: The risk of developing Alzheimer's disease increases with age, with most people being diagnosed after the age of 65.

3. Family history: Having a family history of Alzheimer's disease may increase the risk of developing the condition.

4. Head injuries: A history of head injuries, particularly those that result in loss of consciousness, may increase the risk of Alzheimer's disease.

5. Cardiovascular risk factors: Conditions such as high blood pressure, high cholesterol, and diabetes may increase the risk of developing Alzheimer's disease.

6. Lifestyle factors: A sedentary lifestyle, poor diet, and lack of mental stimulation may increase the risk of Alzheimer's disease.

7. Inflammation: Chronic inflammation in the brain may contribute to the development of Alzheimer's disease.

8. Oxidative stress: An imbalance between the production of free radicals and the body's ability to detoxify them may contribute to the development of Alzheimer's disease.

9. Amyloid plaques and neurofibrillary tangles: The accumulation of amyloid plaques and neurofibrillary tangles in the brain is a hallmark of Alzheimer's disease, but the role they play in the development of the condition is not fully understood.

It is important to note that the cause of Alzheimer's disease is complex and likely involves a combination of these factors.

Research is ongoing to better understand the underlying mechanisms and develop effective treatments for this devastating condition.

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