What causes Alzheimer?

['Pamati hini nga pahina']

Ano an hinungdan han Alzheimer?

An Alzheimer's disease in usa nga progressive neurodegenerative disorder nga nakakaapekto ha utok, nga nagriresulta hin memory loss, cognitive decline, ngan behavioural changes.

An eksakto nga hinungdan han Alzheimer's disease diri gud hinbabaroan, kondi gintotoohan nga resulta ito han kombinasyon han mga butang nga may kalabotan ha henetiko, palibot, ngan estilo han pagkinabuhi.

An pipira han mga hinungdan nga mahimo makabulig ha pag-uswag han Alzheimer's disease nag-uupod han:

1. Henerasyon: May mga gene nga nadiskobrehan nga nagdadugang han posibilidad nga magkaada Alzheimer's disease, labi na an gene nga nag-aaghat han apolipoprotein E (APOE).

2. Edad: An peligro nga magkaada Alzheimer's disease nagtitikadaku samtang nagtitikalagas an usa, ngan kadam-an an nag-aantos hito katapos han 65 anyos.

3. Kasaysayan han Pamilya: An pagkaada kasaysayan han sakit nga Alzheimer ha pamilya mahimo magpadaku han peligro nga magkaada hini nga sakit.

4. Mga Samad ha Ulo: An mga kasaysayan han mga samad ha ulo, labi na adton nagriresulta ha kawara han panhunahuna, mahimo makadugang han peligro han Alzheimer's disease.

5. Mga hinungdan han peligro ha kasingkasing: An mga kahimtang sugad han hitaas nga presyon han dugo, hitaas nga kolesterol, ngan diabetes mahimo makadugang han peligro nga magkaada Alzheimer's disease.

6. Mga hinungdan han estilo han pagkinabuhi: An paglingkod-lingkod, diri maopay nga pagkaon, ngan kakulang hin pagpahuway ha hunahuna mahimo magpadaku han peligro nga magkaada Alzheimer's disease.

7. Paghubag: An maiha nga paghubag ha utok mahimo makaaghat han Alzheimer's disease.

8. Oxidative stress: An diri-pagkatimbang han pagkahimo hin mga free radical ngan han abilidad han lawas ha paglimpyo hito mahimo makabulig ha pagkaada han sakit nga Alzheimer.

9. Amyloid plaques ngan neurofibrillary tangles: An pagtirok han amyloid plaques ngan neurofibrillary tangles ha utok usa nga pangirilal-an han Alzheimer's disease, kondi diri bug-os nga nasasabtan an bahin hito ha pag-uswag han sakit.

Importante nga hinumdoman nga komplikado an hinungdan han Alzheimer's disease ngan posible nga may kalabotan ito ha damu nga hinungdan.

Padayon nga gin-aadman an mga paagi basi mas masabtan an hinungdan hini ngan magkaada epektibo nga mga pagtambal para hini nga makangingirhat nga sakit.

['Mga reperensya']

PubMed/Medline https://www.nlm.nih.gov/databases/download/pubmed_medline.html

RefinedWeb https://arxiv.org/abs/2306.01116

Vellas B, Andrieu S, Cantet C, Dartigues JF, Gauthier S: Long-term changes in ADAS-cog: what is clinically relevant for disease modifying trials in Alzheimer? J Nutr Health Aging. , 11 (4): 338-41.

Braak E, Griffing K, Arai K, Bohl J, Bratzke H, Braak H: Neuropathology of Alzheimer's disease: what is new since A. Alzheimer? Eur Arch Psychiatry Clin Neurosci. 1999, 249 Suppl 3 (): 14-22.

Kovacs GG: Can Creutzfeldt-Jakob disease unravel the mysteries of Alzheimer? Prion. 2016, 10 (5): 369-376.

Cankurtaran M, Yavuz BB, Cankurtaran ES, Halil M, Ulger Z, Ariogul S: Risk factors and type of dementia: vascular or Alzheimer? Arch Gerontol Geriatr. , 47 (1): 25-34.

Mahami-Oskouei M, Hamidi F, Talebi M, Farhoudi M, Taheraghdam AA, Kazemi T, Sadeghi-Bazargani H, Fallah E: Toxoplasmosis and Alzheimer: can Toxoplasma gondii really be introduced as a risk factor in etiology of Alzheimer? Parasitol Res. 2016, 115 (8): 3169-74.

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['An DMCA nagkikinahanglan nga an imo pahibaro hin gin-aakusahan nga pagtalapas han copyright in maglakip han masunod nga impormasyon: (1) paghulagway han copyrighted nga buhat nga gin-aakusahan nga gintatalapas; (2) paghulagway han gin-aakusahan nga nagtalapas nga sulod ngan impormasyon nga igo para makabiling kami han sulod; (3) impormasyon ha pagkontak ha imo, upod an imo adres, numero han telepono ngan email address; (4) usa nga pahayag mo nga mayda ka maopay nga pagtoo nga an sulod ha paagi nga ginreklamo in diri gintutugutan han tag-iya han copyright, o han iya ahente, o han operasyon han bisan ano nga balaud; ']

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['ngan (6) usa nga pisikal o elektronik nga pirma han tag-iya han copyright o hin tawo nga gintutugutan pagbuhat ha ngaran han tag-iya han copyright. ']

['An diri paglakip han ngatanan nga impormasyon ha igbaw mahimo magresulta hin paglangan han pagproseso han imo reklamo.']

['Kontak']

['Alayon pagpadara ha amon hin email hin bisan ano nga pakiana/suggestyon.']

What causes alzheimer?

Alzheimer's disease is a progressive neurodegenerative disorder that primarily affects the brain, causing memory loss, cognitive decline, and behavioral changes.

The exact cause of Alzheimer's disease is not fully understood, but it is believed to result from a combination of genetic, environmental, and lifestyle factors.

Some of the factors that may contribute to the development of Alzheimer's disease include:

1. Genetics: Certain genes have been identified that increase the risk of developing Alzheimer's disease, particularly the apolipoprotein E (APOE) gene.

2. Age: The risk of developing Alzheimer's disease increases with age, with most people being diagnosed after the age of 65.

3. Family history: Having a family history of Alzheimer's disease may increase the risk of developing the condition.

4. Head injuries: A history of head injuries, particularly those that result in loss of consciousness, may increase the risk of Alzheimer's disease.

5. Cardiovascular risk factors: Conditions such as high blood pressure, high cholesterol, and diabetes may increase the risk of developing Alzheimer's disease.

6. Lifestyle factors: A sedentary lifestyle, poor diet, and lack of mental stimulation may increase the risk of Alzheimer's disease.

7. Inflammation: Chronic inflammation in the brain may contribute to the development of Alzheimer's disease.

8. Oxidative stress: An imbalance between the production of free radicals and the body's ability to detoxify them may contribute to the development of Alzheimer's disease.

9. Amyloid plaques and neurofibrillary tangles: The accumulation of amyloid plaques and neurofibrillary tangles in the brain is a hallmark of Alzheimer's disease, but the role they play in the development of the condition is not fully understood.

It is important to note that the cause of Alzheimer's disease is complex and likely involves a combination of these factors.

Research is ongoing to better understand the underlying mechanisms and develop effective treatments for this devastating condition.

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