What is pathophysiology of Diabetes?

['Deungoen halaman nyoe']

Peu pathophysiology diabetes nyan?

Patofisiologi diabetes mengacu bak studi tentang proses fisiologis yang hana teratur yang mengarah bak perkembangan diabetes melitus.

Diabetes mellitus nyankeuh saboh keulompok peunyaket metabolik yang ditanda deungen tingkat gula darah (glukosa) yang tinggi yang akibat dari cacat sekresi insulin, tindakan insulin, atau kedua jih.

Patofisiologi diabetes melibatkan interaksi kompleks faktor genetik, lingkungan, dan gaya hidup yang berkontribusi bak perkembangan penyakit.

Bak diabetes tipe 1, patofisiologi nyan melibatkan kerusakan autoimun sel beta nyang memproduksi insulin bak pankreas, yang meuakibat defisiensi produksi insulin.

Hai nyo meuhase hanjeut geu ato kadar glukosa darah, jeut keu hiperglikemia (gula darah tinggi).

Bak diabetes tipe 2, patofisiologi leubeh kompleks dan melibatkan resistensi insulin dan gangguan sekresi insulin.

Resistensi insulin terjadi wate sel tuboh hana merespon ngen get keu insulin, yang jeut keu ketidakmampuan untuk efektif geu gunakan glukosa keu energi.

Nyo jeut keu peunyebab pankreas geu produksi leubeh jai insulin untuk geu coba mengatasi resistensi, tapi seiring wate, pankreas mungken han jeut geu peu seutot permintaan, yang jeut keu penurunan produksi insulin.

Diabetes gestasional, nyang terjadi seulama kehamilan, disebabkan le perubahan hormon nyang jeut keu resistensi insulin.

Placenta geu produksi hormon nyang jeut geu blok aksi insulin, geu peu ek tingkat glukosa darah

Patofisiologi diabetes nyan na sit perkembangan komplikasi, lage kerusakan pembuluh darah, saraf, dan organ, yang jeut keu masalah kesehatan serius lage peunyaket jantung, stroke, peunyaket ginjal, dan kehilangan penglihatan.

Meuphom patofisiologi diabetes sangat peunteng untuk geu kembangkan perawatan dan strategi pencegahan yang efektif untuk peunyaket kronis nyoe.

['Referensi[peusaneut nè]']

PubMed/Medline https://www.nlm.nih.gov/databases/download/pubmed_medline.html

RefinedWeb https://arxiv.org/abs/2306.01116

Biochemistry and pathophysiology of diabetes. Proceedings of conference on pathophysiology and treatment of diabetes mellitus. 1990. Mol Cell Biochem. 1992, 109 (2): 97-204.

Surampudi PN, John-Kalarickal J, Fonseca VA: Emerging concepts in the pathophysiology of type 2 diabetes mellitus. Mt Sinai J Med. 2009, 76 (3): 216-26.

Johnson D: Selected pathophysiology of diabetes. Semin Perioper Nurs. 1998, 7 (3): 164-78.

Hirsch IB: The changing faces of diabetes. Prim Care. 2003, 30 (3): 499-510.

Guthrie RA, Guthrie DW: Pathophysiology of diabetes mellitus. Crit Care Nurs Q. , 27 (2): 113-25.

Palicka V: Pathophysiology of Diabetes Mellitus. EJIFCC. 2002, 13 (5): 140-144.

Felig P: Pathophysiology of diabetes mellitus. Med Clin North Am. 1971, 55 (4): 821-34.

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What is pathophysiology of diabetes?

Pathophysiology of diabetes refers to the study of the disordered physiological processes that lead to the development of diabetes mellitus.

Diabetes mellitus is a group of metabolic diseases characterized by high blood sugar (glucose) levels that result from defects in insulin secretion, insulin action, or both.

The pathophysiology of diabetes involves the complex interplay of genetic, environmental, and lifestyle factors that contribute to the development of the disease.

In type 1 diabetes, the pathophysiology involves an autoimmune destruction of the insulin-producing beta cells in the pancreas, leading to a deficiency in insulin production.

This results in an inability to regulate blood glucose levels, leading to hyperglycemia (high blood sugar).

In type 2 diabetes, the pathophysiology is more complex and involves both insulin resistance and impaired insulin secretion.

Insulin resistance occurs when the body's cells do not respond properly to insulin, leading to an inability to effectively use glucose for energy.

This causes the pancreas to produce more insulin to try to overcome the resistance, but over time, the pancreas may not be able to keep up with the demand, leading to a decrease in insulin production.

Gestational diabetes, which occurs during pregnancy, is caused by hormonal changes that lead to insulin resistance.

The placenta produces hormones that can block the action of insulin, leading to an increase in blood glucose levels.

The pathophysiology of diabetes also involves the development of complications, such as damage to blood vessels, nerves, and organs, which can lead to serious health problems like heart disease, stroke, kidney disease, and vision loss.

Understanding the pathophysiology of diabetes is crucial for developing effective treatments and prevention strategies for this chronic disease.

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