How to treat Prostate cancer?

['Nin kalan lamɛn']

Seliba bɛ se ka furakɛ cogodi?

Furakɛli fɛɛrɛ caman bɛ se ka sɔrɔ sumaya kunbɛnni na, ka da a kan sumaya bɛ don bana min na ani a juguyara cogo min, ani fana ni banabagatɔ ka kɛnɛyako bɛɛ ye ani a yɛrɛ ka laɲinitaw.

A furakɛli la a tacogo dɔw filɛ:

1. kɔlɔsili ɲuman: O fɛɛrɛ bɛ kansɛri jateminɛ koɲuman ni sɛgɛsɛgɛli ye tuma o tuma, ka sɔrɔ a furakɛli ma daminɛ joona.

A bɛ se ka bɛn cɛw ma farati fitini bɛ minnu ka kansɛri la.

2. Operasiyɔn: Porositɛkitomi ye fɛɛrɛ ye ka musoyalabana (prostate) labɔ.

A bɛ se ka kɛ opereli dayɛlɛlen fɛ walima laparoscopic (ka baara kɛ ni fɛnɲɛnamani misɛnmanw ni minɛn kɛrɛnkɛrɛnnenw ye).

3. kirinni furakɛli: O furakɛli bɛ baara kɛ ni kirinni fangaba ye ka kansɛri banakisɛw faga.

A bɛ se ka don mɔgɔ fari la (minɛn dɔ bɛ a fari kɔkan) walima a tigi kɔnɔ (minɛn dɔ donnen kɔ kuru kɛrɛfɛ).

4. ɔrimɔni furakɛli: O furakɛli bɛ cɛya ɔrimɔni hakɛ dɔgɔya farikolo la (andɔrɔgɛn), min bɛ se ka sumaya lajɔ walima ka sumaya bali.

A bɛ se ka ta a kelen walima ka a fara fura wɛrɛw kan.

Furakɛli minnu bɛ ta walasa ka sumaya kɛlɛ:

A bɛ se ka kɛ ka sumayabana jugumanba furakɛ min jɛnsɛnna ka taa fari fan wɛrɛw la.

6. Bangekɔlɔsi furakɛli: O furakɛli bɛ farikolo dɛmɛ ka kansɛri kɛlɛ.

A bɛ se ka kɛ ka sumayabana jugumanba furakɛ min ma se fura tɔw ma.

7. furakɛli minnu bɛ talikɛ bana kɛrɛn kɛrɛnnenw kan: O furakɛli bɛ talikɛ banakisɛ suguya dɔw kan minnu bɛ kansɛri bana kisɛw dɛmɛ ka bonya ani ka to kɛnɛya la.

A bɛ se ka kɛ ka sumayabana jugumanba furakɛ min ma se fura tɔw ma.

8. Kriyotɛrɛpi: O furakɛli bɛ sumaya jugumanba kɛlɛ walasa ka sumaya banakisɛw faga.

A bɛ se ka kɛ ka sumayabana jugumanba furakɛ walima sumayabana min seginna kɔ fɛ fura wɛrɛw tali kɔ.

9. ultrasoniki farimanba (HIFU): O furakɛli bɛ baara kɛ ni mankan ye min ka teli ka seliliw kansɛri jeni ni ka u halaki.

A bɛ se ka kɛ ka sumayabana jugumanba furakɛ walima sumayabana min seginna kɔ fɛ fura wɛrɛw tali kɔ.

10. kɔlɔsili kɔlɔsili: O ye ka kansɛri jateminɛ kosɛbɛ ni sɛgɛsɛgɛli ye tuma o tuma, nka ka furakɛli daminɛ ni a taamasiɲɛw ma ye walima ni u ma yɛlɛma.

A bɛ se ka bɛn mɔgɔkɔrɔbaw ma minnu ka sumayabana bɛ juguya dɔɔni dɔɔni ani bana gɛlɛnw wɛrɛw.

A nafa ka bon ka furakɛli fɛɛrɛw bɛɛ lajɛ ni kɛnɛyabaarakɛla dɔ ye walasa ka a dɔn fura min ka fisa a tigi ma.

['Sɛbɛnnifɛnw']

PubMed/Medline https://www.nlm.nih.gov/databases/download/pubmed_medline.html

RefinedWeb https://arxiv.org/abs/2306.01116

Wang Y, Chen J, Wu Z, Ding W, Gao S, Gao Y, Xu C: Mechanisms of enzalutamide resistance in castration-resistant prostate cancer and therapeutic strategies to overcome it. Br J Pharmacol. 2021, 178 (2): 239-261.

Talkar SS, Patravale VB: Gene Therapy for Prostate Cancer: A Review. Endocr Metab Immune Disord Drug Targets. 2021, 21 (3): 385-396.

Šamija I, Fröbe A: CHALLENGES IN MANIPULATING IMMUNE SYSTEM TO TREAT PROSTATE CANCER. Acta Clin Croat. 2019, 58 (Suppl 2): 76-81.

Akaza H, Hinotsu S, Usami M, Ogawa O, Kagawa S, Kitamura T, Tsukamoto T, Naito S, Hirao Y, Murai M, Yamanaka H, Namiki M: The case for androgen deprivation as primary therapy for early stage disease: results from J-CaP and CaPSURE. J Urol. 2006, 176 (6 Pt 2): S47-9.

Abraham-Miranda J, Awasthi S, Yamoah K: Immunologic disparities in prostate cancer between American men of African and European descent. Crit Rev Oncol Hematol. 2021, 164 (): 103426.

de Vrij J, Willemsen RA, Lindholm L, Hoeben RC, Bangma CH, Barber C, Behr JP, Briggs S, Carlisle R, Cheng WS, Dautzenberg IJ, de Ridder C, Dzojic H, Erbacher P, Essand M, Fisher K, Frazier A, Georgopoulos LJ, Jennings I, Kochanek S, Koppers-Lalic D, Kraaij R, Kreppel F, Magnusson M, Maitland N, Neuberg P, Nugent R, Ogris M, Remy JS, Scaife M, Schenk-Braat E, Schooten E, Seymour L, Slade M, Szyjanowicz P, Totterman T, Uil TG, Ulbrich K, van der Weel L, van Weerden W, Wagner E, Zuber G: Adenovirus-derived vectors for prostate cancer gene therapy. Hum Gene Ther. 2010, 21 (7): 795-805.

Lee E, Ha S, Logan SK: Divergent Androgen Receptor and Beta-Catenin Signaling in Prostate Cancer Cells. PLoS One. 2015, 10 (10): e0141589.

['Kunnafoni nafama: kɛnɛya']

['Nin gafe in labɛnna kalan ni kunnafoni dɔrɔn de kama, a tɛ sɔrɔ dɔgɔtɔrɔ ka ladili wala kɛnɛyabaarakɛla ka baara kɛcogo la.']

["Kunnafoni minnu dira aw ma, aw man kan ka olu kɛ ka banaw furakɛ. Mɔgɔ minnu b'u yɛrɛ furakɛ, olu ka kan ka dɔgɔtɔrɔ dɔ ka dɛmɛ ɲini."]

["Aw ye aw janto nin na: ɛntɛrinɛti min bɛ jabi di ɲininkaliw jaabiliw kan, o dabali ka jugu kɛrɛnkɛrɛnnenya la n'a bɛ tali kɛ jatidenw de kan. Misali la, mɔgɔ hakɛ min ka bana kofɔra."]

['Aw bɛ ladilikan ɲini tuma bɛɛ aw ka dɔgɔtɔrɔ fɛ walima kɛnɛya baarakɛla dɔ wɛrɛ min bɛ se ka aw dɛmɛ ka aw ka bana furakɛ. Aw kana dɔgɔtɔrɔ ka ladilikan bila ka suma walima ka mɛn a ɲini na sabu aw ye fɛn dɔ kalan nin siti kan. Ni aw hakili la ko aw ka bana bɛ se ka juguya joona, aw ye 911 wele walima aw ka taa aw ka dɔgɔtɔrɔso la joona joona. Nin siti tɛ dɔkɔtɔrɔ ni banabagatɔ ka jɛɲɔgɔnya jira. BioMedLib ni a ka baaradenw, walima nin siti dɛmɛbaga si tɛ kuma si jira walima ka jira, nin kunnafoniw wala u labaarali kama.']

['Kunnafoni min lakodɔnna:']

["Digital Millennium Copyright Act san 1998, 17 U.S.C. § 512 (a DMCA) bɛ sariya sigi ka ɲɛsin mɔgɔ ma min b'a miiri ko fɛn min bɛ sɔrɔ intɛrinɛti kan, o bɛ tɔɲɔ a ka sariyaw la Ameriki jamana ka sariya kɔnɔ. "]

['Ni i dara a la kô i ka site web ni a baara tchogow bè i ka lakananifènw la, i (walima i ka lasigiden) bè se ka i yèrè ka lakananifènw bila ka o site web ni a baara tchogow bila kènèkan.']

['Waajibi don kunnafoniw ci kɛtɔ ka kɛ sɛbɛn ye e-mail fɛ (e-mail de kan ka lajɛ sɛbɛn ɲɛ Kunnafoniw lajɛ yɔrɔ la).']

["DMCA bɛ a ɲini i ka kunnafoni sɛbɛn bɔlɔlɔw kan kojugukɛ sɛbɛn bɛ sɛbɛn min kɔnɔ, o ka kan ka nin kunnafoniw fara a kan: (1) sɛbɛnni kɛtɔ ka sɛbɛnni kɛ min bɛ sɛbɛnni kɛ ni a ma kɛ kojugukɛ sɛbɛn ye; (2) sɛbɛnni kɛtɔ ka fɛn kofɔlen in kofɔ ani kunnafoni minnu bɛ a to an bɛ se ka fɛn kofɔlen in sɔrɔ; (3) i ka ladɛrɛsi, i ka ladɛrɛsi, telefɔni nimɔrɔ ani i ka ladɛrɛsi; (4) i ka kumaɲɔgɔnya sɛbɛn ko i dalen b'a la ko i bɛ a dɔn ko i bɛ ka fɛn kofɔlen in kɛ ni sariya min ye, o ma di sɛbɛnnikɛbaga ma, a ka ladɛrɛsi tigi, walima sariya wɛrɛ; "]

['(5) a ka seereyasɛbɛ sɛbɛntiya, ko seereyasɛbɛ minɛnen bɛ kojugubakɛlaw kama, ko kunnafoni min bɛ o sɛbɛntiya kɔnɔ, ko tiɲɛ don ani ko i yamaruyalen don ka yamaruya di ka kɛwalew kɛ minnu bɛ tiɲɛni kɛ; ']

['ani (6) sɛbɛn dɔ ka boloci walima ɛkitɔrɔniki sɛbɛn sɛbɛn tigi fɛ walima mɔgɔ min yamaruyara ka baara kɛ sɛbɛn tigi tɔgɔla. ']

['Ni kunnafoni fɔlen ninnu bɛɛ ma fara ɲɔgɔn kan, o bɛ se ka kɛ sababu ye ka mɛn baara kɛli la i ka sɛbɛn kɔnɔ.']

['Ɲɔgɔnkunbɛn']

['Sɛbɛn ɲɛ Ɲiningaliw / ladiliw']

How to treat prostate cancer?

There are several treatment options available for prostate cancer, depending on the stage and aggressiveness of the cancer, as well as the patient's overall health and personal preferences.

Some common treatments include:

1. Active surveillance: This approach involves closely monitoring the cancer with regular checkups and tests, rather than immediately starting treatment.

It may be suitable for men with low-risk prostate cancer.

2. Surgery: A prostatectomy is a surgical procedure to remove the prostate gland.

It can be done through open surgery or laparoscopically (using small incisions and specialized tools).

3. Radiation therapy: This treatment uses high-energy radiation to kill cancer cells.

It can be delivered externally (from a machine outside the body) or internally (through implants placed near the tumor).

4. Hormone therapy: This treatment reduces the levels of male hormones (androgens) in the body, which can slow or stop the growth of prostate cancer.

It can be used alone or in combination with other treatments.

5. Chemotherapy: This treatment uses drugs to kill cancer cells.

It may be used for advanced prostate cancer that has spread to other parts of the body.

6. Immunotherapy: This treatment helps the immune system fight cancer.

It may be used for advanced prostate cancer that has not responded to other treatments.

7. Targeted therapy: This treatment targets specific genes or proteins that help cancer cells grow and survive.

It may be used for advanced prostate cancer that has not responded to other treatments.

8. Cryotherapy: This treatment uses extreme cold to freeze and kill cancer cells.

It may be used for early-stage prostate cancer or for cancer that has come back after other treatments.

9. High-intensity focused ultrasound (HIFU): This treatment uses high-frequency sound waves to heat and destroy cancer cells.

It may be used for early-stage prostate cancer or for cancer that has come back after other treatments.

10. Watchful waiting: This approach involves closely monitoring the cancer with regular checkups and tests, but not starting treatment unless symptoms appear or change.

It may be suitable for older men with slow-growing prostate cancer and other serious health conditions.

It is important to discuss all treatment options with a healthcare team to determine the best course of action for each individual case.

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