What are the risk factors for Alzheimer?

['Nin kalan lamɛn']

Kun jumɛn na jolidɛsɛ bɛ mɔgɔ minɛ?

Kun caman bɛ yen minnu bɛ se ka kɛ sababu ye ka mɔgɔ bila sidabana la, i n'a fɔ:

1. si: Ni mɔgɔ si bɛ kɔrɔya ka taa a fɛ, a ka teli ka kɛ ko a bɛ bana min sɔrɔ, o ye Alzheimer ye.

2. joli siraw: Ni a bɛ sɔrɔ a tigi somɔgɔ dɔ la walima joli sira dɔw, i n'a fɔ APOE-e4 joli sira, o bɛ se ka dɔ fara a ka bana sɔrɔli farati kan.

Kunkolo joginni: Kunkolo joginni jugumanba walima basi caman bɔli bɛ se ka laban ni kirinni ye.

4. Dusukun tantanni bana: Bana minnu bɛ mɔgɔ dusukun tantanni gɛlɛya ani ka joli siraw tiɲɛ, i n'a fɔ tansiyɔn yɛlɛlen, sukaro, ani sumaya, olu bɛ se ka kɛ sababu ye ka mɔgɔ caman ka bana.

5. Balocogo: Sigarɛtimin, dɔlɔmin kojugu ani farikoloɲɛnajɛbaliya bɛ se ka sumaya bila mɔgɔ la.

6. Miiriya sɔrɔbaliya: Miiriya sɔrɔbaliya ani kalan sɔrɔbaliya bɛ se ka dɔ fara mɔgɔ ka sumaya sɔrɔli kan.

Sinɔgɔbaliya: Sinɔgɔbaliya, i n'a fɔ ninakili sumayali sunɔgɔ la, o bɛ se ka laban ni sumaya ye.

8. Farikolo tanabanaw: Dusukasikow, degun ani sigida mɔgɔw ka mabɔ ɲɔgɔn na, olu bɛ se ka kɛ sababu ye ka mɔgɔ caman ka bana.

A nafa ka bon ka a dɔn ko farati kelen walima a caman minnu kofɔlen don, olu tɛ a jira ko a tigi bɛna bana sɔrɔ abada.

Nka, farati ninnu dɔnni bɛ se ka mɔgɔ dɛmɛ ka a ka faratiw dɔgɔya ani ka a hakili sigi.

['Sɛbɛnnifɛnw']

PubMed/Medline https://www.nlm.nih.gov/databases/download/pubmed_medline.html

RefinedWeb https://arxiv.org/abs/2306.01116

Borenstein AR, Copenhaver CI, Mortimer JA: Early-life risk factors for Alzheimer disease. Alzheimer Dis Assoc Disord. , 20 (1): 63-72.

Pansari K, Gupta A, Thomas P: Alzheimer's disease and vascular factors: facts and theories. Int J Clin Pract. 2002, 56 (3): 197-203.

Kivipelto M, Helkala EL, Laakso MP, Hänninen T, Hallikainen M, Alhainen K, Iivonen S, Mannermaa A, Tuomilehto J, Nissinen A, Soininen H: Apolipoprotein E epsilon4 allele, elevated midlife total cholesterol level, and high midlife systolic blood pressure are independent risk factors for late-life Alzheimer disease. Ann Intern Med. 2002, 137 (3): 149-55.

Skoog I, Kalaria RN, Breteler MM: Vascular factors and Alzheimer disease. Alzheimer Dis Assoc Disord. , 13 Suppl 3 (): S106-14.

Bidzan L: [Initial symptoms and risk factors in Alzheimer's dementia]. Psychiatr Pol. , 28 (2): 207-19.

Gorelick PB: Risk factors for vascular dementia and Alzheimer disease. Stroke. 2004, 35 (11 Suppl 1): 2620-2.

Kummer BR, Diaz I, Wu X, Aaroe AE, Chen ML, Iadecola C, Kamel H, Navi BB: Associations between cerebrovascular risk factors and parkinson disease. Ann Neurol. 2019, 86 (4): 572-581.

Luchsinger JA, Reitz C, Honig LS, Tang MX, Shea S, Mayeux R: Aggregation of vascular risk factors and risk of incident Alzheimer disease. Neurology. 2005, 65 (4): 545-51.

['Kunnafoni nafama: kɛnɛya']

['Nin gafe in labɛnna kalan ni kunnafoni dɔrɔn de kama, a tɛ sɔrɔ dɔgɔtɔrɔ ka ladili wala kɛnɛyabaarakɛla ka baara kɛcogo la.']

["Kunnafoni minnu dira aw ma, aw man kan ka olu kɛ ka banaw furakɛ. Mɔgɔ minnu b'u yɛrɛ furakɛ, olu ka kan ka dɔgɔtɔrɔ dɔ ka dɛmɛ ɲini."]

["Aw ye aw janto nin na: ɛntɛrinɛti min bɛ jabi di ɲininkaliw jaabiliw kan, o dabali ka jugu kɛrɛnkɛrɛnnenya la n'a bɛ tali kɛ jatidenw de kan. Misali la, mɔgɔ hakɛ min ka bana kofɔra."]

['Aw bɛ ladilikan ɲini tuma bɛɛ aw ka dɔgɔtɔrɔ fɛ walima kɛnɛya baarakɛla dɔ wɛrɛ min bɛ se ka aw dɛmɛ ka aw ka bana furakɛ. Aw kana dɔgɔtɔrɔ ka ladilikan bila ka suma walima ka mɛn a ɲini na sabu aw ye fɛn dɔ kalan nin siti kan. Ni aw hakili la ko aw ka bana bɛ se ka juguya joona, aw ye 911 wele walima aw ka taa aw ka dɔgɔtɔrɔso la joona joona. Nin siti tɛ dɔkɔtɔrɔ ni banabagatɔ ka jɛɲɔgɔnya jira. BioMedLib ni a ka baaradenw, walima nin siti dɛmɛbaga si tɛ kuma si jira walima ka jira, nin kunnafoniw wala u labaarali kama.']

['Kunnafoni min lakodɔnna:']

["Digital Millennium Copyright Act san 1998, 17 U.S.C. § 512 (a DMCA) bɛ sariya sigi ka ɲɛsin mɔgɔ ma min b'a miiri ko fɛn min bɛ sɔrɔ intɛrinɛti kan, o bɛ tɔɲɔ a ka sariyaw la Ameriki jamana ka sariya kɔnɔ. "]

['Ni i dara a la kô i ka site web ni a baara tchogow bè i ka lakananifènw la, i (walima i ka lasigiden) bè se ka i yèrè ka lakananifènw bila ka o site web ni a baara tchogow bila kènèkan.']

['Waajibi don kunnafoniw ci kɛtɔ ka kɛ sɛbɛn ye e-mail fɛ (e-mail de kan ka lajɛ sɛbɛn ɲɛ Kunnafoniw lajɛ yɔrɔ la).']

["DMCA bɛ a ɲini i ka kunnafoni sɛbɛn bɔlɔlɔw kan kojugukɛ sɛbɛn bɛ sɛbɛn min kɔnɔ, o ka kan ka nin kunnafoniw fara a kan: (1) sɛbɛnni kɛtɔ ka sɛbɛnni kɛ min bɛ sɛbɛnni kɛ ni a ma kɛ kojugukɛ sɛbɛn ye; (2) sɛbɛnni kɛtɔ ka fɛn kofɔlen in kofɔ ani kunnafoni minnu bɛ a to an bɛ se ka fɛn kofɔlen in sɔrɔ; (3) i ka ladɛrɛsi, i ka ladɛrɛsi, telefɔni nimɔrɔ ani i ka ladɛrɛsi; (4) i ka kumaɲɔgɔnya sɛbɛn ko i dalen b'a la ko i bɛ a dɔn ko i bɛ ka fɛn kofɔlen in kɛ ni sariya min ye, o ma di sɛbɛnnikɛbaga ma, a ka ladɛrɛsi tigi, walima sariya wɛrɛ; "]

['(5) a ka seereyasɛbɛ sɛbɛntiya, ko seereyasɛbɛ minɛnen bɛ kojugubakɛlaw kama, ko kunnafoni min bɛ o sɛbɛntiya kɔnɔ, ko tiɲɛ don ani ko i yamaruyalen don ka yamaruya di ka kɛwalew kɛ minnu bɛ tiɲɛni kɛ; ']

['ani (6) sɛbɛn dɔ ka boloci walima ɛkitɔrɔniki sɛbɛn sɛbɛn tigi fɛ walima mɔgɔ min yamaruyara ka baara kɛ sɛbɛn tigi tɔgɔla. ']

['Ni kunnafoni fɔlen ninnu bɛɛ ma fara ɲɔgɔn kan, o bɛ se ka kɛ sababu ye ka mɛn baara kɛli la i ka sɛbɛn kɔnɔ.']

['Ɲɔgɔnkunbɛn']

['Sɛbɛn ɲɛ Ɲiningaliw / ladiliw']

What are the risk factors for alzheimer?

There are several risk factors for Alzheimer's disease, including:

1. Age: The risk of developing Alzheimer's disease increases with age, with most people being diagnosed after the age of 65.

2. Genetics: Having a family history of Alzheimer's disease or carrying certain genes, such as the APOE-e4 gene, can increase the risk of developing the disease.

3. Head injury: A history of severe head trauma or multiple concussions may increase the risk of Alzheimer's disease.

4. Cardiovascular health: Conditions that affect the heart and blood vessels, such as high blood pressure, high cholesterol, diabetes, and obesity, may increase the risk of Alzheimer's disease.

5. Lifestyle factors: Smoking, excessive alcohol consumption, and lack of physical exercise may increase the risk of Alzheimer's disease.

6. Cognitive inactivity: A lack of mental stimulation and low levels of education may increase the risk of Alzheimer's disease.

7. Sleep disorders: Sleep disorders, such as sleep apnea, may increase the risk of Alzheimer's disease.

8. Psychological factors: Depression, stress, and social isolation may increase the risk of Alzheimer's disease.

It is important to note that having one or more of these risk factors does not necessarily mean that a person will develop Alzheimer's disease, and some people with no known risk factors may still develop the disease.

However, understanding these risk factors can help individuals take steps to reduce their risk and promote brain health.

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