Pansari K, Gupta A, Thomas P: Alzheimer's disease and vascular factors: facts and theories. Int J Clin Pract. 2002, 56 (3): 197-203.
Kivipelto M, Helkala EL, Laakso MP, Hänninen T, Hallikainen M, Alhainen K, Iivonen S, Mannermaa A, Tuomilehto J, Nissinen A, Soininen H: Apolipoprotein E epsilon4 allele, elevated midlife total cholesterol level, and high midlife systolic blood pressure are independent risk factors for late-life Alzheimer disease. Ann Intern Med. 2002, 137 (3): 149-55.
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There are several risk factors for Alzheimer's disease, including:
1. Age: The risk of developing Alzheimer's disease increases with age, with most people being diagnosed after the age of 65.
2. Genetics: Having a family history of Alzheimer's disease or carrying certain genes, such as the APOE-e4 gene, can increase the risk of developing the disease.
3. Head injury: A history of severe head trauma or multiple concussions may increase the risk of Alzheimer's disease.
4. Cardiovascular health: Conditions that affect the heart and blood vessels, such as high blood pressure, high cholesterol, diabetes, and obesity, may increase the risk of Alzheimer's disease.
5. Lifestyle factors: Smoking, excessive alcohol consumption, and lack of physical exercise may increase the risk of Alzheimer's disease.
6. Cognitive inactivity: A lack of mental stimulation and low levels of education may increase the risk of Alzheimer's disease.
7. Sleep disorders: Sleep disorders, such as sleep apnea, may increase the risk of Alzheimer's disease.
8. Psychological factors: Depression, stress, and social isolation may increase the risk of Alzheimer's disease.
It is important to note that having one or more of these risk factors does not necessarily mean that a person will develop Alzheimer's disease, and some people with no known risk factors may still develop the disease.
However, understanding these risk factors can help individuals take steps to reduce their risk and promote brain health.
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