How is Alzheimer diagnosed?

['A lamɛn']

O bana be sɔrɔ cogo di?

O la, u b'a sɛgɛsɛgɛ koɲuman, k'a ka miiriya lɔn ani k'a sɛgɛsɛgɛ.

1. Dɔgɔtɔrɔ dɔ ka sɛgɛsɛgɛli: Dɔgɔtɔrɔ dɔ bena i sɛgɛsɛgɛ ani k'a filɛ i ka bana cogoya.

2. Miiriya ani dusukunnakow sɛgɛsɛgɛli: O sɛgɛsɛgɛliw be mɔgɔ hakili sigi, a be se ka kuma ani ka koo dɔw faamu.

3. Miiriya: Miiriya dɔw be se k'a to an b'a fɔ ko an ka ɲi ka baara kɛ ni an ka hakili ye walisa ka bana dɔw furakɛ.

O fɛɛrɛ be se ka poroteyini dɔw hakɛ suma, minw be sumaya bila mɔgɔ la.

4. jolisɛgɛsɛgɛ: Sɛgɛsɛgɛri kuraw b'a yira ko jolisɛgɛsɛgɛ dɔw be se k'a to an b'a lɔn ni bana dɔ b'an na.

5. A be se ka kɛ ko bana dɔ tɛ mɔgɔ minɛ cogo nɔgɔman na.

A kɔrɔtanin lo an k'a lɔn ko ni mɔgɔ sara, a ka ɲi ka sɛgɛsɛgɛri kɛ a hakili la walisa k'a lɔn ni bana tɛ ale la.

Nka, bi, a ka nɔgɔ ka banaw lɔn ka ɲɛ.

A ka ɲi ka kɔn k'a ɲini k'a lɔn bana min b'a la walisa ka se ka furakɛli daminɛ ani ka siniɲasigi labɛn.

['Kunnafoni wɛrɛw']

PubMed/Medline https://www.nlm.nih.gov/databases/download/pubmed_medline.html

RefinedWeb https://arxiv.org/abs/2306.01116

Liu SS, Zhu SQ: [Correlation between Alzheimer disease and cataract]. Zhonghua Yan Ke Za Zhi. 2017, 53 (4): 314-316.

Gauthier S: Practical guidelines for the antemortem diagnosis of senile dementia of the Alzheimer type. Prog Neuropsychopharmacol Biol Psychiatry. 1985, 9 (5-6): 491-5.

Rubin R: New Test to Help Diagnose Alzheimer Disease. JAMA. 2022, 327 (23): 2281.

[Blood Based Biomarker for Optimization of Early and Differential Diagnosis of Alzheimer's Dementia]. Fortschr Neurol Psychiatr. 2022, 90 (7-08): 326-335.

Kapp MB: Physicians' legal duties regarding the use of genetic tests to predict and diagnose Alzheimer disease. J Leg Med. 2000, 21 (4): 445-75.

Britschgi M, Wyss-Coray T: Blood protein signature for the early diagnosis of Alzheimer disease. Arch Neurol. 2009, 66 (2): 161-5.

Volicer L, Berman SA, Cipolloni PB, Mandell A: Persistent vegetative state in Alzheimer disease. Does it exist? Arch Neurol. 1997, 54 (11): 1382-4.

Imabayashi E, Saitoh Y, Tsukamoto T, Sakata M, Takano H: Combination of Astrogliosis and Phosphorylated Tau for the Preclinical Diagnosis of Alzheimer Disease Using 3-Dimensional Stereotactic Surface Projection Images With 18 F-THK5351. Clin Nucl Med. 2022, 47 (12): 1066-1068.

Martínez A, Lahiri DK, Giacobini E, Greig NH: Advances in Alzheimer therapy: understanding pharmacological approaches to the disease. Curr Alzheimer Res. 2009, 6 (2): 83-5.

['Kunnafoni nafaman: furakɛli']

["O site web nin labɛnna walisa ka mɔgɔw kalan ani k'u kunnafoni dɔrɔn."]

["Mɔgɔ minw b'o gafew kalan, olu man kan k'u kɛ ka bana dɔw furakɛ."]

['Aw ye aw janto nin na: ɛntɛrinɛti min bɛ ɲiningaliw jaabiw labɛn, a tɛ se ka jatidenw fɔ ka ɲɛ. misali la, bana kɛrɛnkɛrɛnnen dɔ bɛ mɔgɔ minw na.']

["Tuma bɛɛ i ka kan ka ladili ɲini i ka dɔgɔtɔrɔ fɛ wala kɛnɛya baarakɛla dɔ fɛ bana dɔ koo la. I kana ban ka ladili ɲini dɔgɔtɔrɔ fɛ wala ka mɛɛn a ɲinili la sabu i ye koo dɔ kalan site web nin kan. N'i miirila ko bana dɔ be i kan, i ka kan ka teliya ka mɔgɔ wele 911 wala ka taga dɔgɔtɔrɔso la joona joona."]

['Kunnafoniw: sɛbɛkɔrɔ']

["Digital Millennium Copyright Act of 1998, 17 U.S.C. § 512 (DMCA) ye sariya dɔ ye min b'a to mɔgɔ minw b'u ka gafew sɔrɔ ɛntɛrinɛti kan, olu ka se k'u yɛrɛ lafasa."]

["N'i lanin b'a la ko kunnafoni wala fɛɛn o fɛɛn be sɔrɔ an ka site web kan wala an ka baaraw kan, k'o be i ka sariya tiɲɛ, i (wala i ka lasigiden) be se k'o kunnafoni wala fɛɛn bɔ yen wala k'a bali k'a sɔrɔ."]

['I ka kan ka ci nin ci nin kɛ e-mail fɛ (i ka e-mail lajɛ yɔrɔ nin na)']

["DMCA b'a ɲini ko i ka kunnafoni nunu fara i ka kunnafoni kan: (1) kunnafoni min b'a yira ko i ye baara dɔ kɛ min ka kan ni sariya ye; (2) kunnafoni min b'a yira ko i ye baara dɔ kɛ min ma sariya labato ani kunnafoni wɛrɛw minw b'a to an be se k'o kunnafoni sɔrɔ; (3) i ka ladɛrɛsi, telefɔni nimɔrɔ ani e-mail; (4) i ka seereya dɔ ko i lanin b'a la ko i ye baara min kɛ, ko sariya t'o kɛ."]

["5. i ka sɛbɛ dɔ kɛ ka yira ko i ye tiɲɛn fɔ ani ko joo b'i fɛ ka joo dɔ latanga."]

["O kama, a ka ɲi i k'a ɲini k'a lɔn n'i ka ɲi k'o gafew wala videwo nunu jati k'u ye gafew ye minw labɛnna mɔgɔw ye."]

["N'i ma kunnafoni nunu bɛɛ di, a be se ka kɛ ko i ka ɲinini baara be mɛɛn."]

['Kumaɲɔgɔnya kɛ']

["N'i ka ɲiningaliw wala i ka ladiliw be yen, an ci e-mail fɛ."]

How is alzheimer diagnosed?

Alzheimer's disease is diagnosed through a combination of methods, including a thorough medical evaluation, cognitive and neuropsychological tests, brain imaging, and the process of elimination of other possible causes.

1. Medical evaluation: A doctor will perform a physical examination and take a detailed medical history to rule out other possible causes of memory loss or cognitive decline, such as thyroid problems, vitamin deficiencies, or brain tumors.

2. Cognitive and neuropsychological tests: These tests assess memory, language, problem-solving, and other cognitive functions to determine the extent of cognitive impairment and to differentiate between normal age-related memory loss and dementia.

3. Brain imaging: Magnetic resonance imaging (MRI) or computed tomography (CT) scans can help identify structural changes in the brain that may indicate Alzheimer's disease.

Positron emission tomography (PET) scans can also be used to measure the levels of certain proteins associated with Alzheimer's disease.

4. Blood tests: Recent research has shown that certain blood tests can help diagnose Alzheimer's disease by measuring the levels of specific proteins or biomarkers associated with the disease.

5. Process of elimination: Since there is no single definitive test for Alzheimer's disease, diagnosis often involves ruling out other possible causes of dementia-like symptoms.

It is important to note that a definitive diagnosis of Alzheimer's disease can only be made after death through an examination of brain tissue.

However, current diagnostic methods can provide a high level of certainty for a clinical diagnosis while the person is still alive.

Early diagnosis is important for starting treatment and planning for the future.

Disclaimer: medical

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