Etɛ ka nyí azɔmɛ agbaza tɔn dó azɔnkwín kolon tɔn wu?
Akpáxwé è nɔ dó azɔnkwín kolon tɔn é nɔ dó gesí nǔ ɖěɖee nɔ zɔ́n bɔ é nɔ jɛji é.
Azɔnkwín kolon tɔn e è nɔ lɛ́ ylɔ́ ɖɔ kansɛ́ɛ kolonɔ́lɛ́tɛli é nyí azɔnkwín alɔkpa ɖé bɔ é nɔ bɛ́ ɖò kolon alǒ kanmɛ̀, è nɔ ylɔ́ ɖɔ agba ɔ sín akpáxwé ɖé lɛ.
É nɔ bɛ́ hwɛhwɛ ɖò nǔ e nɔ sù ɖò agbaza ɔ mɛ bɔ è nɔ ylɔ ɖɔ polyp é ɖé mɛ, bɔ é sixu wá huzu kansɛ́ɛ ɖò nukɔnmɛ.
Akpáxwé vovo wɛ nɔ zɔ́n bɔ è nɔ ɖó kansɛ́n xomɛfɔnnɔ, ɖi ɖyɔɖyɔ nǔɖògbɛ lɛ tɔn, nǔ nɔ dó xomɛfɔnnɔ mɛ lɛ é kpo nǔ ɖevo lɛ kpo.
È sixu ɖó ɖyɔɖyɔ nǔɖògbɛ e nɔ huzu DNA ɖò xwi ɖíɖó lɛ mɛ é, bɔ enɛ nɔ zɔ́n bɔ xwi ɖíɖó lɛ nɔ sù bo nɔ má yeɖée.
È sixu ɖu gǔ alǒ ɖó jijɔ enɛ lɛ, bɔ ye sixu wà nǔ dó nǔwukpikpé e è nɔ ɖó bo nɔ bló bɔ nǔwukpikpé nùɖé lɛ tɔn nɔ sù, nɔ má, bo nɔ vɔ́ nǔ ɖ'ayǐ lɛ é wu.
Akɔ́njízɔn e nɔ ɖò jijɛji wɛ hwebǐnu é sixu zɔ́n bɔ è nɔ ɖè nùɖé lɛ tɔ́n ɖò agbaza mɛ bɔ ye nɔ zɔ́n bɔ nǔ lɛ nɔ sù bo nɔ má yeɖée, bɔ enɛ sixu zɔ́n bɔ kansɛ́ɛ na wá.
Nǔ ɖěɖee nɔ wà nǔ dó gbɛzán mɛ wu lɛ é ɖi nùɖuɖu, gbɛzinzan, kpo nǔ ɖěɖee è nɔ ɖó ɖò azɔ̌mɛ lɛ é kpo lɔ sixu zɔ́n bɔ è nɔ jɛ kansɛ́ɛ́n ɖaxó ɖé jí.
Ði kpɔ́ndéwú ɔ, è mɔ ɖɔ enyi è ɖu nǔ e nɔ ɖó lan vɔvɔ kpo lan e è ɖà nǔ lɛ é kpo gègě é ɔ, é nɔ zɔ́n bɔ è nɔ ɖó awovinú ɖaxó lɛ.
Nǔ ɖevo lɛ ɖi nǔɖokan zinzan, azɔ nunu, kpo nǔ ma wà ganji ɖò agbaza lixo ǎ kpo sixu zɔ́n bɔ azɔn ɔ syɛn.
Enyi è ko ɖó kansɛ́n xomɛ tɔn ɔ, é sixu yì nukɔn ɖò akpáxwé gègě mɛ, sín kansɛ́n e ɖò nukɔnmɛ bɔ è nɔ mɔ ɖò xomɛ ɔ mɛ jɛ kansɛ́n e yì nukɔn bɔ é gbakpé fí ɖevo lɛ ɖò agbaza mɛ é jí.
Kansɛ́ɛ́li lɛ sixu byɔ agbaza e sɛkpɔ ye é kpo agbaza sín wǔjɔnú e ɖò ye kpá lɛ é kpo mɛ, bo lɛ́ sixu gbló ada gbɔn kanjɔjɔkan lɛ mɛ yì fí línlín lɛ, ɖi ɖiɖi mɛ alǒ funfún mɛ.
Alɔwliwli nú kansɛ́n xomɛ tɔn nɔ byɔ ɖɔ è ni bló amasin, bo dó wli azinzɔnnɔ lɛ, lobo dó wli ye, bɔ é nɔ sín kansɛ́n ɔ sín ninɔmɛ kpo fí e é ɖè é kpo wu.
Azɔnkwín è nɔ dó xomɛsín xomɛ lɛ́ɛ ɔ́' è nɔ mɔ azɔn yetɔn lɛ́ɛ ɖò hwenu è ko ɖò azɔn ɔ́ sín azɔnkwín nukɔntɔn lɛ́ɛ mɛ é.
Nukɔnkpénúmɛ hwɛhwɛ lɛ, ɖi nǔ kpɔ́n dó xomɛ mɛ, bo nɔ kpɔ́n nǔ dó xomɛ mɛ, sixu d'alɔ bɔ è na mɔ kansɛ́n xomɛ tɔn ɖò bǐbɛ̌mɛ, hwenu e è sixu kpéwú bo gbɔ azɔn n'i hugǎn é.
Vidal-Vanaclocha F: The liver prometastatic reaction of cancer patients: implications for microenvironment-dependent colon cancer gene regulation. Cancer Microenviron. 2011, 4 (2): 163-80.
Yagi T, Kubota E, Koyama H, Tanaka T, Kataoka H, Imaeda K, Joh T: Glucagon promotes colon cancer cell growth via regulating AMPK and MAPK pathways. Oncotarget. 2018, 9 (12): 10650-10664.
Sharma SH, Thulasingam S, Nagarajan S: Terpenoids as anti-colon cancer agents - A comprehensive review on its mechanistic perspectives. Eur J Pharmacol. 2017, 795 (): 169-178.
Keshk WA, Zineldeen DH, Wasfy RE, El-Khadrawy OH: Fatty acid synthase/oxidized low-density lipoprotein as metabolic oncogenes linking obesity to colon cancer via NF-kappa B in Egyptians. Med Oncol. 2014, 31 (10): 192.
Dongfeng D, An C, Shujia P, Jikai Y, Tao Y, Rui D, Kai T, Yafeng C, Jianguo L, Xilin D: Explanation of colon cancer pathophysiology through analyzing the disrupted homeostasis of bile acids. Afr Health Sci. 2014, 14 (4): 925-8.
Tammali R, Ramana KV, Srivastava SK: Aldose reductase regulates TNF-alpha-induced PGE2 production in human colon cancer cells. Cancer Lett. 2007, 252 (2): 299-306.
['Nǔgbɛnúmɛ: dotóoxwé sín']
['Nǔkplɔnkplɔn kpo nǔsisɔ kpo sín azɔ̌ kɛɖɛ wɛ è nɔ wà dó tɛn ɛntɛnɛti tɔn elɔ jí, bo nɔ na wěɖexámɛ dotóoxwé tɔn alǒ azɔ̌ ɖevo lɛ mɛ ǎ.']
['È ɖó na zán nǔ e è kplɔ́n mɛ lɛ é dó ba azɔn ɖé alǒ azɔn ɖé sín wuntun alǒ dó gbɔ na ǎ, bɔ mɛ ɖěɖee jló na ba wěɖexámɛ dotóo tɔn lɛ é ɖó na yì mɔ dotóo e ɖó acɛ bo nɔ wà azɔ̌ ɖò dotóoxwé é ɖé.']
['Mi ni flín ɖɔ nǔ e è nɔ ylɔ ɖɔ "neural net" bo nɔ na xósin nú nǔkanbyɔ lɛ é ɔ, nǔ e nɔ nyí nǔjɛdo tawun é wɛ nyí nǔ ɖěɖee è nɔ ylɔ ɖɔ "numeric content" lɛ é. Ði kpɔ́ndéwú ɔ, mɛ nabi è mɔ azɔn ɖé na é.']
['Nɔ ba wěɖexámɛ dotóo towe tɔn alǒ dotóo ɖevo e ɖó nǔwukpikpé é tɔn dó azɔn ɖé wu hwebǐnu. Ma wɔn wěɖexámɛ dotóo tɔn lɛ gbeɖé ó, alǒ ma lin tamɛ kpɔ́n dó nǔ e a xà ɖò tɛn ɛntɛnɛti tɔn elɔ jí lɛ é wu ó. Enyi a lin ɖɔ azɔn baɖabaɖa ɖé ɖò xwi ɖí xá we wɛ hǔn, ylɔ 911 alǒ yì dotóoxwé e sɛkpɔ we hugǎn é tlolo. Tɛn ɛntɛnɛti tɔn elɔ alǒ nǔ e a nɔ zán lɛ é nɔ zɔ́n bɔ kancica dotóo-azinzɔnnɔ ɖé tɔn nɔ tíìn ǎ. BioMedLib, azɔ̌watɔ́ tɔn lɛ, alǒ mɛ ɖevo ɖebǔ e nɔ wlan nǔ dó tɛn ɛntɛnɛti tɔn elɔ jí lɛ é nɔ ɖè kúnnuɖenú ɖebǔ xlɛ́, bo tlɛ nɔ ɖɔ lɔ ǎ, dó nǔ e è ɖɔ ɖò fí lɛ é alǒ nǔ e è nɔ zán lɛ é wu.']
['Nǔɖògbɛ́jlatɔ́ lɛ']
['Digital Millennium Copyright Act of 1998, 17 U.S.C. § 512 (the DMCA) nɔ na acɛ mɛ e ɖó nǔɖokan yetɔn lɛ é bɔ ye na dó ba nǔɖe bo dó sixu mɔ nǔ e ye ɖó lɛ é ɖò Internet jí.']
["Enyi a ɖi nǔ ɖɔ nǔ ɖĕbǔ ɖò tɛn ɛntɛnɛti tɔn mǐtɔn jí alǒ azɔ̌wiwa mǐtɔn lɛ jí bo hɛn nǔ dó así nú mɛ ɔ, é xò nǔ dó acɛ nǔɖògbɛ́ towe lɛ wu ɔ, hwi (alǒ mɛ e nɔ kpé nukún dó wǔ towe é) sixu sɛ́ wɛn dó mǐ, bo byɔ ɖɔ mǐ ni ɖè nǔ ɖ'emɛ lɛ sín tɛn ɔ jí, alǒ ɖɔ mǐ ni sú ali dó mɛ."]
["È ɖó ná sɛ́ mɛ dó gbɔn email jí (e-mail è nɔ dó ɔ́' kpɔ́n 'Kɔntaktɔ́' ɔ́)."]
['DMCA byɔ ɖɔ ɖɔ nǔ elɔ lɛ ni nɔ akpáxwé nǔ e a ɖɔ é gbà acɛ dó nǔ é tɔn jí é: (1) xó dó azɔ̌ e ɖó acɛ dó nǔ é jí; (2) xó dó nǔ e ɖó acɛ dó nǔ é jí, kpo nǔ ɖevo e na zɔ́n bɔ mǐ na mɔ nǔ ɔ lɛ é kpo; (3) xó dó hwiɖée wu, ɖi adlɛsi towe, alokan towe kpo email towe kpo; (4) xó ɖɔ dó nǔ e wu a ɖi nǔ ɖɔ nǔ e ɖó acɛ dó nǔ e jí a ɖɔ é jí é kún nyí nǔ e ɖó acɛ dó nǔ é jí tɔn ɔ, alǒ mɛ e nɔ kpé nukún dó nǔ é tɔn wu é sín acɛ ó; ']
["(5) Ðɛ́ mɛ̀ è mi sɔ́ alɔ dó ɖ'así ná ɖò hwɛɖɔxɔsá ɔ́' è ɖó ná ɖó hwɛ̀ ɖɔ̀ xó è mi ɖɔ ɖò mɛ̀ è mi dó wèmá ɔ́ mɛ̀ ɔ́' sɔgbe bɔ̀ mi ɖó acɛ̀ bó ná dó ba ɖɔ è ní sú nǔ è è dó wèmá ɔ́ wú lɛ́ɛ sín axɔ́."]
['bɔ (6) alɔ wlanwlan mɛ e ɖó acɛ dó nǔ é tɔn alǒ mɛ e ɖó acɛ bo na wà nǔ dó wutu tɔn é tɔn. ']
['Nú a ma gɔ́ nǔ e ɖò jí lɛ é bǐ ǎ ɔ, é sixu zɔ́n bɔ è na lín có bo na dóhwɛ we.']
['Wǎ kpé mì']
['Mi kɛnklɛn bo sɛ́ nǔkanbyɔ mitɔn lɛ dó mǐ gbɔn e-mail jí.']
What is pathophysiology of colon cancer?
The pathophysiology of colon cancer refers to the underlying mechanisms and processes that lead to the development and progression of colon cancer.
Colon cancer, also known as colorectal cancer, is a type of cancer that begins in the colon or rectum, which are parts of the large intestine.
It typically starts as a growth called a polyp, which can develop into cancer over time.
The pathophysiology of colon cancer involves several factors, including genetic mutations, inflammation, and environmental factors.
Genetic mutations can occur in the DNA of colon cells, leading to uncontrolled cell growth and division.
These mutations can be inherited or acquired, and they can affect various genes involved in cell growth, division, and repair.
Inflammation in the colon, which can be caused by conditions such as inflammatory bowel disease, can also increase the risk of colon cancer.
Chronic inflammation can lead to the release of chemicals that promote cell growth and division, potentially leading to the development of cancer.
Environmental factors, such as diet, lifestyle, and exposure to certain chemicals, can also contribute to the development of colon cancer.
A diet high in red and processed meats, for example, has been linked to an increased risk of colon cancer.
Other factors, such as obesity, smoking, and lack of physical activity, can also increase the risk.
Once colon cancer develops, it can progress through several stages, from early-stage cancer that is confined to the colon to more advanced stages where the cancer has spread to other parts of the body.
The cancer cells can invade nearby tissues and organs, and may also spread through the lymphatic system or bloodstream to distant sites, such as the liver or lungs.
Treatment for colon cancer typically involves a combination of surgery, chemotherapy, and radiation therapy, depending on the stage and location of the cancer.
Early detection and treatment are key to improving outcomes, as colon cancer is often curable when caught in its early stages.
Regular screening, such as colonoscopy, can help detect colon cancer at its earliest stages, when it is most treatable.
Disclaimer: medical
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Disclaimer: copyright
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['E ɖò']
['BioMedLib nɔ zán ordinateur lɛ (algorithme nǔ kplɔnkplɔn mɔto tɔn lɛ) bo nɔ dó kàn nǔ byɔ mɛ lɛ bo nɔ lɛ́ na ye xósin.']
['Mǐ bɛ́ kpodo azɔwanú lanmɛ kpo lanmɛ kpo tɔn livi 35 e ɖò PubMed/Medline lɛ é kpo. Mǐ lɛ́ vɔ́ mɔ tɛn ɛntɛnɛti tɔn RefinedWeb tɔn lɛ.']
