What is pathophysiology of Diabetes?

['Nan jaawal ndu']

Ko woni patofisioloji nyau nyau je suklare?

Pathophysiology nyau nyau je ɗon larni jaangirde yahde yahde ɓandu je ɗon yahida be yahde nyau je ɗon yahida be yahde nyau je ɗon.

Nyau ɓernde je ɗon mari no ɓandu ɗon mari nyauji je ɗon holla no suklare (glucose) woni ha nder iyam ngam nyauji je ɗon salla wurtinugo insulin, kugal insulin, mala ɗiɗi fu.

Pathophysiology nyau nyau je suklare ɗon larna hawtirde sababuji renol, wakkere, be dabare jonde je ɗon mballa yahde nyau ndu.

Ha nder nyau nyau type 1, pathophysiology ɗon larna mbarol ɓaandu je ɗon waɗa insulin ha nder beta cellji ha nder ɓaandu, je ɗon waɗa insulin waɗa no ha nder ɓaandu.

Ndu ɗon hokka dabare darnugo daraja gulukoos nder iyam, je ɗon yahda be hyperglycemia (sukkaare nder iyam je ɗon mawna).

Ha nder nyau nyau type 2, pathophysiology ɗon mari saɗirma e ɗon larna ɓaandu je ɗon no salla be insulin be ustol wurtinol insulin.

Wullaandu insulin ɗon wangi to ɓikkoy ɓaandu jaabata be insulin no haani, je ɗon hokka dabare huwugo be glucose ngam heɓugo sembe.

Ndu ɗon hokka ɓaandu wurtina insulin jur ngam foondugo heɓugo sembe, amma ha wakati feere, ɓaandu footay heɓɓa sembe, ngam maajum wurtinol insulin usti.

Nyau ɓesdugo ɓaandu, je ɗon wangi ha wakati reedu, ɗon wangi ngam saanjolji nder ɓaandu je ɗon yahida be darnol insulin.

Ɓinngel ɓingel ɗon wurtina hormoneji je footi haɗɗa kugal insulin, je ɗon yahda be ɓesdugo suklare nder iyam.

Pathophysiology nyau nyau je ɗon mari nyau je ɗon larni yahde nyauji feere, bana hurgol iyam, neebamji, be ɓaandu, je footi yahida be nyauji feere bana nyau ɓernde, ɓernde, nyauji ɓaandu, be majjugo gite.

Fahmugo pathophysiology nyau nyau je suklare lati kanduɗum ngam wurtinugo dabareji hurgol be fadol je ɗon naffa ngam nyau je ɗon neeɓa ndu.

['Ɗaɓɓitol']

PubMed/Medline https://www.nlm.nih.gov/databases/download/pubmed_medline.html

RefinedWeb https://arxiv.org/abs/2306.01116

Biochemistry and pathophysiology of diabetes. Proceedings of conference on pathophysiology and treatment of diabetes mellitus. 1990. Mol Cell Biochem. 1992, 109 (2): 97-204.

Surampudi PN, John-Kalarickal J, Fonseca VA: Emerging concepts in the pathophysiology of type 2 diabetes mellitus. Mt Sinai J Med. 2009, 76 (3): 216-26.

Johnson D: Selected pathophysiology of diabetes. Semin Perioper Nurs. 1998, 7 (3): 164-78.

Hirsch IB: The changing faces of diabetes. Prim Care. 2003, 30 (3): 499-510.

Guthrie RA, Guthrie DW: Pathophysiology of diabetes mellitus. Crit Care Nurs Q. , 27 (2): 113-25.

Palicka V: Pathophysiology of Diabetes Mellitus. EJIFCC. 2002, 13 (5): 140-144.

Felig P: Pathophysiology of diabetes mellitus. Med Clin North Am. 1971, 55 (4): 821-34.

['Wurtinol: jam ɓaandu']

['Web site ndu ɗon hokka ngam ekkitol be matinolji tan e wala bana hokkugo feeloji do jam ɓaandu mala kuɗe.']

["Matinolji je ɗon hokka footay huwire ngam lartol mala hurgol nyau mala nyauji, e ɓe'en je ɗon ɗaɓɓita feelo lekki sey ɓe laara do lekkitajo je mari jaawal."]

['Ladde ngam matinolji je ɗon wurtina jaawabuji do emmolji, lati bana je ɗon mari limgal je ɗon larni nyauɓe.']

['Footi a ɗaɓɓita jaahargal do lekkitajo ma mala goɗɗo dokkoowo jam ɓaandu je mari daama do nyau ma. Taa meema jaahargal do lekkitajo mala neeɓu ɗaɓɓugo ndu ngam ko a jaangi ha do wakkere web ndu. To a tammi a footi mara nyau jaawal, ewna 911 mala yah ha suudu jaawal je ɓadi ma be law. Wala alaka lekkitajo be nyauɗo je ɗon wangina gal wakkere web ndu mala huwugo ndu. BioMedLib mala huwooɓe ma, mala goɗɗo je ɗon walli ha wakkere web ndu, ɗon wolwa, ɗon holla mala ɗon nufa, do matinolji je ɗon hokka ha nder ndu mala huwugo ndu.']

['Wurtinol hakke: copyright']

["Digital Millennium Copyright Act je 1998, 17 U.S.C. § 512 (DMCA) ɗon hokka dabare ngam marɓe hakkeji je ɗon hoola yo'o kujeji je ɗon wangi ha do Internet ɗon luuta hakkeji maɓɓe do dooka hakkeji je Lesɗe America. "]

["To a ɗon nuɗɗini be nuɗɗinki boɗɗum yo'o kujeji mala kujeji je ɗon no wondi be web site mala kuɗe amin ɗon meema ceede je mari, an (mala wakili'en ma) footi nelda amin matinol je ɗon emma ngam ittugo kujeji mala kujeji, mala haɗugo heɓugo ndu. "]

['Matinolji sey nelda be ɗerewol gal emayel (laaru "Contact" ngam emayel).']

["DMCA yiɗi matinolji je ɗon bana ɗon larni matinolji je ɗon tokkitini: (1) tindol kugal je mari hakkeji je ɗon larni je ɗon tokkitini; (2) tindol kuje je ɗon larni je ɗon larni e matinolji je ɗon mari hakkeji je ɗon mari haaje ngam en heɓta kuje man; (3) matinolji ngam a wonda be ma, be lamar, lamba telefon be lamar email; (4) matinol je a holli a ɗon hoola be goonga yo'o kuje je ɗon no ɗon holla bana ɗon larni wala jaɓol marɗo hakkeji, mala wakiilijo maako, mala gal kugal dookaaji; "]

['(5) matinolji je on windi, je on windi ha les bone seedugo fewre, je matinolji ha nder matinolji man lati goonga e je on mari baawɗe ngam aynugo hakkeji je mbiyotto ɗon luuta;']

['e (6) jungo je ɗon mari hakkeji mala jungo je ɗon mari bawɗe huwugo ngam inde je mari hakkeji. ']

['Wattinugo matinolji je woni ha ton footi waɗa jaawal ngam jaɓɓugo do ngulli maɗa.']

['Wondugo']

['Lorte ha amin be emel to a mari ƴamol/dabare.']

What is pathophysiology of diabetes?

Pathophysiology of diabetes refers to the study of the disordered physiological processes that lead to the development of diabetes mellitus.

Diabetes mellitus is a group of metabolic diseases characterized by high blood sugar (glucose) levels that result from defects in insulin secretion, insulin action, or both.

The pathophysiology of diabetes involves the complex interplay of genetic, environmental, and lifestyle factors that contribute to the development of the disease.

In type 1 diabetes, the pathophysiology involves an autoimmune destruction of the insulin-producing beta cells in the pancreas, leading to a deficiency in insulin production.

This results in an inability to regulate blood glucose levels, leading to hyperglycemia (high blood sugar).

In type 2 diabetes, the pathophysiology is more complex and involves both insulin resistance and impaired insulin secretion.

Insulin resistance occurs when the body's cells do not respond properly to insulin, leading to an inability to effectively use glucose for energy.

This causes the pancreas to produce more insulin to try to overcome the resistance, but over time, the pancreas may not be able to keep up with the demand, leading to a decrease in insulin production.

Gestational diabetes, which occurs during pregnancy, is caused by hormonal changes that lead to insulin resistance.

The placenta produces hormones that can block the action of insulin, leading to an increase in blood glucose levels.

The pathophysiology of diabetes also involves the development of complications, such as damage to blood vessels, nerves, and organs, which can lead to serious health problems like heart disease, stroke, kidney disease, and vision loss.

Understanding the pathophysiology of diabetes is crucial for developing effective treatments and prevention strategies for this chronic disease.

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