Tha pathophysiology aillse sgamhain a 'toirt iomradh air na h-atharrachaidhean anns na pròiseasan agus na h-innealan fiseòlasach àbhaisteach a thachras ann an leasachadh agus adhartas aillse sgamhain.
Tha aillse sgamhain na ghalar iom-fhillte a tha ag èirigh bho fhàs agus roinn neo-riaghlaichte cheallan neo-àbhaisteach anns na sgamhain.
Faodaidh na ceallan sin tumors a chruthachadh agus sgaoileadh gu pàirtean eile den bhodhaig, a 'leantainn gu diofar chomharraidhean agus duilgheadasan.
Tha pathophysiology aillse sgamhain a 'toirt a-steach grunn fhactaran, a' toirt a-steach atharrachaidhean ginteil, factaran àrainneachd, agus roghainnean dòigh-beatha.
Faodaidh atharrachaidhean ginteil tachairt ann an DNA cheallan sgamhain, a' leantainn gu fàs agus roinn chealla neo-riaghlaichte.
Faodar na h-atharrachaidhean sin a bhith air an oighreachadh no air an faighinn, agus faodaidh iad a bhith air an adhbhrachadh le bhith fosgailte do carcinogens, leithid ceò tombaca, radon, asbestos, agus truailleadh adhair.
Faodar aillse sgamhain a sheòrsachadh ann an dà phrìomh sheòrsa: aillse sgamhain cealla beag (SCLC) agus aillse sgamhain cealla neo-bheag (NSCLC).
Faodaidh pathophysiology nan seòrsaichean aillse sgamhain sin a bhith eadar-dhealaichte, oir tha atharrachaidhean ginteil eadar-dhealaichte aca agus bidh iad a 'freagairt gu eadar-dhealaichte ri làimhseachadh.
Tha pathophysiology aillse sgamhain cuideachd a' toirt a-steach eadar-obrachadh eadar ceallan aillse agus an fhèith mun cuairt, a' gabhail a-steach an t-siostam dìon.
Faodaidh ceallan aillse an siostam dìon a sheachnadh, a' leigeil leotha fàs agus sgaoileadh gun smachd.
A bharrachd air an sin, faodaidh an microenvironment tumhair fàs tumhair agus metastasis adhartachadh le bhith a 'toirt àrainneachd taiceil do cheallan aillse.
Tha pathophysiology aillse sgamhain na phròiseas iom-fhillte agus fiùghantach, agus tha luchd-rannsachaidh ag obair gu leantainneach gus tuigse nas fheàrr fhaighinn air na h-innealan bunaiteach gus leigheasan nas èifeachdaiche a leasachadh agus toraidhean euslaintich a leasachadh.
Li Z, Qian Y, Li W, Liu L, Yu L, Liu X, Wu G, Wang Y, Luo W, Fang F, Liu Y, Song F, Cai Z, Chen W, Huang W: Human Lung Adenocarcinoma-Derived Organoid Models for Drug Screening. iScience. 2020, 23 (8): 101411.
Nurwidya F, Syahruddin E, Yunus F: Pain management in lung cancer. Adv Respir Med. 2016, 84 (6): 331-336.
Khan KA, Kennedy MP, Moore E, Crush L, Prendeville S, Maher MM, Burke L, Henry MT: Radiological characteristics, histological features and clinical outcomes of lung cancer patients with coexistent idiopathic pulmonary fibrosis. Lung. 2015, 193 (1): 71-7.
Paramanantham A, Asfiya R, Das S, McCully G, Srivastava A: Extracellular Vesicle (EVs) Associated Non-Coding RNAs in Lung Cancer and Therapeutics. Int J Mol Sci. 2022, 23 (21): .
Lee D, Kim Y, Chung C: Scientific Validation and Clinical Application of Lung Cancer Organoids. Cells. 2021, 10 (11): .
Mucchietto V, Crespi A, Fasoli F, Clementi F, Gotti C: Neuronal Acetylcholine Nicotinic Receptors as New Targets for Lung Cancer Treatment. Curr Pharm Des. 2016, 22 (14): 2160-9.
['Àicheadh: meidigeach']
["Tha an làrach-lìn seo air a thoirt seachad airson adhbharan foghlaim agus fiosrachaidh a-mhàin agus chan eil e a' toirt seachad comhairle mheidigeach no seirbheisean proifeiseanta."]
["Cha bu chòir am fiosrachadh a chaidh a thoirt seachad a chleachdadh airson duilgheadas slàinte no galar a dhearbhadh no a làimhseachadh, agus bu chòir dhaibhsan a tha a'sireadh comhairle meidigeach pearsanta co-chomhairle a chumail ri lighiche-sprèidh."]
["Thoiribh fa-near gu bheil an lìon neural a tha a' cruthachadh fhreagairtean do na ceistean, gu sònraichte neo-chruinneasach nuair a thig e gu susbaint àireamhach. Mar eisimpleir, an àireamh de dhaoine a chaidh a dhearbhadh le galar sònraichte."]
["Faigh comhairle an dotair agad no solaraiche slàinte eile a tha airidh air comhairle a thaobh tinneas meidigeach. Na dì-meas comhairle meidigeach proifeiseanta no dàil ann a bhith ga shireadh air sgàth rudeigin a leugh thu air an làrach-lìn seo. Ma tha thu a'smaoineachadh gum faodadh èiginn meidigeach a bhith agad, cuir fòn gu 911 no rachaibh chun t-seòmar èiginn as fhaisge sa bhad. Chan eil dàimh dotair-euslainteach air a chruthachadh leis an làrach-lìn seo no a chleachdadh. Chan eil BioMedLib no a luchd-obrach, no neach sam bith a tha a' cur ris an làrach-lìn seo, a 'dèanamh riochdachaidhean sam bith, fosgailte no a' toirt a-steach, a thaobh an fhiosrachaidh a tha air a thoirt seachad an seo no a chleachdadh."]
['Àicheadh: còraichean']
["Tha Achd Dlighe-sgrìobhaidh na Mìle Bliadhna Didseatach 1998, 17 U.S.C. § 512 (an DMCA) a' toirt ath-chuinge do shealbhadairean dlighe-sgrìobhaidh a tha den bheachd gu bheil stuth a tha a' nochdadh air an eadar-lìon a' briseadh an còraichean fo lagh dlighe-sgrìobhaidh na SA. "]
["Ma tha thu a' creidsinn ann an deagh chreideamh gu bheil susbaint no stuth sam bith a tha ri fhaotainn a thaobh ar làrach-lìn no ar seirbheisean a' briseadh d' dlighe-sgrìobhaidh, faodaidh tu fhèin (no an riochdaire agad) fios a chur thugainn ag iarraidh gun tèid an susbaint no an stuth a thoirt air falbh, no gun tèid cothrom a chur air. "]
["Feumar sanasan a chur ann an sgrìobhadh tro phost-d (faic an roinn 'Contact' airson seòladh puist-d). "]
["Tha an DMCA ag iarraidh gum bi am fiosrachadh a leanas anns an fhios agad mu bhriseadh còraichean-sgrìobhaidh a thathar ag ràdh: (1) tuairisgeul air an obair fo chòraichean-sgrìobhaidh a tha fo chasaid briseadh; (2) tuairisgeul air an t-susbaint a thathar ag ràdh a tha a 'briseadh agus fiosrachadh gu leòr gus leigeil leinn an t-susbaint a lorg; (3) fiosrachadh conaltraidh dhut, a' toirt a-steach do sheòladh, àireamh fòn agus seòladh puist-d; (4) aithris bhuat gu bheil creideas math agad nach eil an t-susbaint san dòigh a tha gearan air a cheadachadh le sealbhadair a 'chòraichean-sgrìobhaidh, no an neach-ionaid aige, no le gnìomh lagha sam bith; "]
['(5) Dearbhadh agaibh, air a shoidhnigeadh fo pheanas mionnachaidh, gu bheil am fiosrachadh san fhiosrachadh ceart agus gu bheil ùghdarras agaibh na còraichean-sgrìobhaidh a thathar ag ràdh a chaidh a bhriseadh a chur an gnìomh; ']
['agus (6) ainm-sgrìobhte corporra no eileagtronaigeach an t-sealbhadair dlighe-sgrìobhaidh no neach a tha ùghdarraichte a bhith ag obair às leth an t-sealbhadair dlighe-sgrìobhaidh. ']
["Ma dh'fhailicheas tu air a' ghearan agad a dheasachadh, faodaidh e dàil a chur air mura cuir thu a-steach am fiosrachadh gu lèir gu h-àrd."]
['Cuir fios thugainn']
['Cuir post-d thugainn le ceist / moladh sam bith.']
What is pathophysiology of lung cancer?
The pathophysiology of lung cancer refers to the changes in the normal physiological processes and mechanisms that occur in the development and progression of lung cancer.
Lung cancer is a complex disease that arises from the uncontrolled growth and division of abnormal cells in the lungs.
These cells can form tumors and spread to other parts of the body, leading to various symptoms and complications.
The pathophysiology of lung cancer involves several factors, including genetic mutations, environmental factors, and lifestyle choices.
Genetic mutations can occur in the DNA of lung cells, leading to uncontrolled cell growth and division.
These mutations can be inherited or acquired, and they can be caused by exposure to carcinogens, such as tobacco smoke, radon, asbestos, and air pollution.
Lung cancer can be classified into two main types: small cell lung cancer (SCLC) and non-small cell lung cancer (NSCLC). NSCLC is further divided into three subtypes: adenocarcinoma, squamous cell carcinoma, and large cell carcinoma.
The pathophysiology of these types of lung cancer can differ, as they have different genetic mutations and respond differently to treatment.
The pathophysiology of lung cancer also involves the interaction between cancer cells and the surrounding tissue, including the immune system.
Cancer cells can evade the immune system, allowing them to grow and spread unchecked.
Additionally, the tumor microenvironment can promote tumor growth and metastasis by providing a supportive environment for cancer cells.
The pathophysiology of lung cancer is a complex and dynamic process, and researchers are continuously working to better understand the underlying mechanisms to develop more effective treatments and improve patient outcomes.
Disclaimer: medical
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['Mu dheidhinn']
["Bidh BioMedLib a' cleachdadh choimpiutairean fèin-ghluasadach (algorithms ionnsachaidh innealan) gus paidhrichean ceist is freagairt a chruthachadh."]
["Bidh sinn a' tòiseachadh le 35 millean foillseachadh bith-leigheis de PubMed/Medline. Cuideachd, duilleagan-lìn de RefinedWeb."]
