How is Alzheimer diagnosed?

['Ehendu ko kuatiarogue']

Mba'éichapa ojeikuaa Alzheimer mba'asy?

Alzheimer mba'asy ojekuaa heta método rupive, oikehápe peteĩ evaluación médica ipypukúva, prueba cognitiva ha neuropsicológica, imagen cerebral ha ambue mba'e ikatúva oporombohasy.

1. Ñepohano: Peteĩ pohãnohára ojapóta peteĩ examen físico ha oikuaáta mba'eichaguápa hína ne mba'asy, ohecha hag̃ua ambue mba'e ikatúva omokangy ne mandu'a térã ne apytu'ũ, taha'e tiroides mba'asy, vitamina deficiencia térã tumor cerebral.

2. Prueba cognitiva ha neuropsicológica: Ko'ã prueba oha'ã memoria, ñe'ẽ, apañuãi ñembohovái ha ambue función cognitiva ojehechakuaa hag̃ua deterioro cognitivo ha oñembojoavy hag̃ua pérdida de memoria normal ha demencia ojoajúva edad rehe.

3. Apytu'ũ ñemoha'ãnga: Imágenes de resonancia magnética (IRM) térã tomografía computarizada (TC) ikatu oipytyvõ ojeikuaa hag̃ua umi apytu'ũ ñemoambue estructura rehegua ikatúva ohechauka Alzheimer mba'asy.

Tomografía por emisión de positrones (PET) jehecha ikatu avei ojeporu ojeipapa hag̃ua nivel oĩva proteína ojoajúva Alzheimer mba'asy rehe.

4. Tuguy ñeha'ã: Jehapereka ramovegua ohechauka oĩha tuguy ñeha'ã ikatuha oipytyvõ ojeikuaa hag̃ua Alzheimer mba'asy, ojehecha rire proteína térã biomarcador específico nivel ojoajúva mba'asy rehe.

5. Ñemboguete: Ndaipóri rupi peteĩ prueba añónte Alzheimer mba'asýpe g̃uarã, diagnóstico py'ỹinte oiko ojeipe'ávo ambue mba'e ikatúva ogueru demencia-icha síntoma.

Iporã ja'e peteĩ mba'asy Alzheimer rehegua ikatuha ojehecha peteĩ tapicha omano rire añoite peteĩ examen del tejido cerebral rupive.

Upéicharamo jepe, umi método de diagnóstico ko'agãgua ikatu ome'ẽ peteĩ alto nivel de certeza peteĩ diagnóstico clínico-pe g̃uarã tapicha oikove aja gueteri.

Diagnosticar pya'e ningo tuichaiterei mba'e oñepyrũ haguã ñepohano ha oñembosako'i haguã tenonderã.

['Jehechapy']

PubMed/Medline https://www.nlm.nih.gov/databases/download/pubmed_medline.html

RefinedWeb https://arxiv.org/abs/2306.01116

Liu SS, Zhu SQ: [Correlation between Alzheimer disease and cataract]. Zhonghua Yan Ke Za Zhi. 2017, 53 (4): 314-316.

Gauthier S: Practical guidelines for the antemortem diagnosis of senile dementia of the Alzheimer type. Prog Neuropsychopharmacol Biol Psychiatry. 1985, 9 (5-6): 491-5.

Rubin R: New Test to Help Diagnose Alzheimer Disease. JAMA. 2022, 327 (23): 2281.

[Blood Based Biomarker for Optimization of Early and Differential Diagnosis of Alzheimer's Dementia]. Fortschr Neurol Psychiatr. 2022, 90 (7-08): 326-335.

Kapp MB: Physicians' legal duties regarding the use of genetic tests to predict and diagnose Alzheimer disease. J Leg Med. 2000, 21 (4): 445-75.

Britschgi M, Wyss-Coray T: Blood protein signature for the early diagnosis of Alzheimer disease. Arch Neurol. 2009, 66 (2): 161-5.

Volicer L, Berman SA, Cipolloni PB, Mandell A: Persistent vegetative state in Alzheimer disease. Does it exist? Arch Neurol. 1997, 54 (11): 1382-4.

Imabayashi E, Saitoh Y, Tsukamoto T, Sakata M, Takano H: Combination of Astrogliosis and Phosphorylated Tau for the Preclinical Diagnosis of Alzheimer Disease Using 3-Dimensional Stereotactic Surface Projection Images With 18 F-THK5351. Clin Nucl Med. 2022, 47 (12): 1066-1068.

Martínez A, Lahiri DK, Giacobini E, Greig NH: Advances in Alzheimer therapy: understanding pharmacological approaches to the disease. Curr Alzheimer Res. 2009, 6 (2): 83-5.

['Ñemboyke: pohã']

["Ko página web niko ñehekombo'e ha marandu rehegua añónte, ndaha'éi ñeporandu térã ñepytyvõ pohãnohárape."]

["Ko marandu oñeme'ẽva ndojeporúi va'erã ojeikuaa térã oñepohano hag̃ua peteĩ problema de salud térã mba'asy, ha umi tapicha ohekáva consejo médico ha'eñoháme oñe'ẽva'erã peteĩ pohanohára ikatupyrýva ndive."]

["Ejesareko ta'ãngamýi ñandutigua omoheñóiva mbohovái porandukuérape, noĩporãi ojeipapávo papapy rehegua, techapyrã, tapichakuéra hasýva peteĩ mba'asýpe."]

["Akóinte eheka ne pohãnohára térã ambue pohanohára ikatupyrýva ñe'ẽ peteĩ mba'asýpe. Ani araka'eve remboyke térã reha'arõ'ỹ rehekávo ñe'ẽ pohanohára ikatupyrýva ñe'ẽ remoñe'ẽre ko ñanduti rendápe. Reimo'ãramo ikatuha reikotevẽ peteĩ mba'e hasýva, ehenoikuaa 911 térã tereho pya'e tasyópe. Ko ñanduti renda térã ijeporu ndojapói mba'eveichagua pohanohára ha hasýva jokupyty. BioMedLib, imba'apohára térã oimeraẽ tapicha oipytyvõva ko ñanduti rendápe, nomboajéi mba'eve, he'íva térã he'iséva, marandu oĩva ko'ápe térã ijeporu."]

['Copyright: Copyright']

["Pe Digital Millennium Copyright Act of 1998, 17 U.S.C. § 512 (DMCA) ome'ẽ recurso umi copyright járape ogueroviáva umi mba'e ojehechaukáva Internet-pe opokovaiha iderecho rehe EE.UU. léi jehaiporãmby rehegua rupive. "]

["Rogueroviáramo añetehápe oimeraẽ mba'e térã tembiporu ojepurukuaáva ore ñanduti renda térã tembipurupyahu rupive opyrũha ne derécho rehe, nde (térã ne rembijokuái) ikatu oremondo peteĩ ñemomarandu ojerurévo ojeipe'a hag̃ua upe mba'e térã tembiporu, térã ojejokopa hag̃ua ijeike. "]

['Umi ñemomarandu oñemog̃uahẽva\'erã kuatia rupive, correo electrónico rupive (ojehecháta "Contacto" pe).']

["DMCA ojerure ne ñemomarandu rehe ejaposégui mba'evai ejaposéva rehe toike ko'ã mba'e: (1) tembiapo ojejaposéva rehegua ha'éva mba'evai; (2) jehaipy ha mba'ekuaarã ome'ẽva oréve jehaipyre ha'éva mba'evai ha ome'ẽva oréve pa'ũ rojuhu hag̃ua; (3) ne ñanduti veve, ne rendaite, ne pumbyry papapy ha ne ñanduti veve; (4) ñe'ẽme'ẽ erekóva rejeroviaha pe mba'evai ejaposéva rehe ndojeruréiha mba'evai apohára, imaranduhára térã léi."]

["5. peteî declaración nde rejapóva, remoîva nde réra ha remoîva'erâha nde jurúpe, umi mba'e oîva ñemomarandúpe oîmbaha añetehápe ha rerekoha pokatu remoañete haguâ umi derecho oje'éva nde rehe ojepoko vaiha;"]

["ha (6) peteĩ firma física térã electrónica copyright jára rehegua térã peteĩ tapicha omoneĩva oporoñemomba'e hag̃ua copyright jára rérape. "]

["Ndoikéi ramo opaite ko'ã mba'e ikatu ombohape nde denuncia ñemboguata."]

['Ñemboheraguapy']

["Remba'eporanduséramo térã ereko hag̃ua ne remiandu ehai oréve."]

How is alzheimer diagnosed?

Alzheimer's disease is diagnosed through a combination of methods, including a thorough medical evaluation, cognitive and neuropsychological tests, brain imaging, and the process of elimination of other possible causes.

1. Medical evaluation: A doctor will perform a physical examination and take a detailed medical history to rule out other possible causes of memory loss or cognitive decline, such as thyroid problems, vitamin deficiencies, or brain tumors.

2. Cognitive and neuropsychological tests: These tests assess memory, language, problem-solving, and other cognitive functions to determine the extent of cognitive impairment and to differentiate between normal age-related memory loss and dementia.

3. Brain imaging: Magnetic resonance imaging (MRI) or computed tomography (CT) scans can help identify structural changes in the brain that may indicate Alzheimer's disease.

Positron emission tomography (PET) scans can also be used to measure the levels of certain proteins associated with Alzheimer's disease.

4. Blood tests: Recent research has shown that certain blood tests can help diagnose Alzheimer's disease by measuring the levels of specific proteins or biomarkers associated with the disease.

5. Process of elimination: Since there is no single definitive test for Alzheimer's disease, diagnosis often involves ruling out other possible causes of dementia-like symptoms.

It is important to note that a definitive diagnosis of Alzheimer's disease can only be made after death through an examination of brain tissue.

However, current diagnostic methods can provide a high level of certainty for a clinical diagnosis while the person is still alive.

Early diagnosis is important for starting treatment and planning for the future.

Disclaimer: medical

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Disclaimer: copyright

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