Mũrimũ wa Alzheimer wonekaga na njĩra itiganĩte, ta gũthuthurio na njĩra ndikĩru, gũthimwo meciria na meciria ma mũndũ, gũthima tombo, na gũthima maũndũ mangĩ marĩa mangĩtũma woneke.
1. Ũthuthuria wa ndagĩtarĩ: Ndagĩtarĩ nĩ agũthuthuria na amenye maũndũ mothe megiĩ mũrimũ ũcio nĩguo amenye kana hihi nĩ harĩ maũndũ mangĩ matũmĩte mũndũ ariganĩrũo kana aremwo nĩ gwĩciria, ta mũrimũ wa thyroid, kwaga vitamini cia kũigana, kana kansa ya tombo.
2. Ũthuthuria wa meciria na wa meciria: Ũthuthuria ũcio ũthuthuragia ũhoti wa mũndũ wa kũririkana, rũthiomi, ũhoti wa gũtua matua, na maũndũ mangĩ megiĩ ũhoti wa gwĩciria nĩguo ũmenye ũrĩa mũndũ ũcio arĩ na thĩna ũcio na ũhote gũkũũrana ũritũ wa kũririkana maũndũ marĩa mũndũ acokagĩrũo nĩmo nĩ ũndũ wa ũkũrũ na gũkua meciria.
3. Ũthuthuria wa tomography wa tombo: Ũthuthuria wa magnetic resonance imaging (MRI) kana computed tomography (CT) no ũteithie kũmenya mogarũrũku ma tombo marĩa mangĩonania mũrimũ wa Alzheimer.
Ningĩ ũthuthuria wa tomography (PET) no ũhũthĩrũo gũthima gĩthimi kĩa proteins imwe iria ikoragwo na mũrimũ wa Alzheimer.
4. Ũthuthuria wa thakame: Ũthuthuria wa ica ikuhĩ nĩ wonanĩtie atĩ ũthuthuria mũna wa thakame no ũteithie kũmenya mũrimũ wa Alzheimer kũgerera gũthima gĩthimi kĩa proteini kana indo ingĩ iria cionanagia mũrimũ ũcio.
5. Njĩra ya gwĩthema: Tondũ gũtirĩ njĩra ĩmwe tu ya gũthima mũndũ arĩ na mũrimũ wa Alzheimer, kaingĩ mũndũ athimaga mũrimũ ũcio akĩgeria gwĩthema maũndũ mangĩ marĩa mangĩtũma mũndũ ambĩrĩrie kũgĩa na mũrimũ ũcio.
Nĩ wega kũririkana atĩ mũrimũ wa Alzheimer no woneke wega tu thutha wa mũndũ gũkua na njĩra ya gũthuthuria tombo.
O na kũrĩ ũguo, njĩra cia ũtuĩria iria ihũthagĩrũo ũmũthĩ no itũme mũndũ agĩe na ũũma biũ atĩ arĩ na mũrimũ ũcio o na arĩ muoyo.
Kũmenya mũrimũ tene nĩ kwa bata nĩguo mũndũ ambĩrĩrie kũrigitwo na kũbanga ũrĩa egwĩka thutha-inĩ.
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Rubin R: New Test to Help Diagnose Alzheimer Disease. JAMA. 2022, 327 (23): 2281.
[Blood Based Biomarker for Optimization of Early and Differential Diagnosis of Alzheimer's Dementia]. Fortschr Neurol Psychiatr. 2022, 90 (7-08): 326-335.
Kapp MB: Physicians' legal duties regarding the use of genetic tests to predict and diagnose Alzheimer disease. J Leg Med. 2000, 21 (4): 445-75.
Britschgi M, Wyss-Coray T: Blood protein signature for the early diagnosis of Alzheimer disease. Arch Neurol. 2009, 66 (2): 161-5.
Volicer L, Berman SA, Cipolloni PB, Mandell A: Persistent vegetative state in Alzheimer disease. Does it exist? Arch Neurol. 1997, 54 (11): 1382-4.
Imabayashi E, Saitoh Y, Tsukamoto T, Sakata M, Takano H: Combination of Astrogliosis and Phosphorylated Tau for the Preclinical Diagnosis of Alzheimer Disease Using 3-Dimensional Stereotactic Surface Projection Images With 18 F-THK5351. Clin Nucl Med. 2022, 47 (12): 1066-1068.
Martínez A, Lahiri DK, Giacobini E, Greig NH: Advances in Alzheimer therapy: understanding pharmacological approaches to the disease. Curr Alzheimer Res. 2009, 6 (2): 83-5.
['Ũkaana: thibitarĩ']
['Website ĩno ĩkoragwo ĩrĩ ya kũrutana na kũheana ũhoro tu na ti ya kũheana ũtaaro wa ũrigitani kana ũtungata wa kĩĩmwĩrĩ.']
['Ũhoro ũrĩa ũrĩ thĩinĩ wa broshua ĩyo ndwagĩrĩirũo kũhũthĩrũo gũthima kana kũrigita mũrimũ mũna, na arĩa marenda ũtaaro wa ũrigitani magĩrĩirũo gũcaria ũteithio wa ndagĩtarĩ.']
['No wone atĩ netiwaki ya neuron ĩrĩa ĩheanaga macokio ma ciũria icio, ndĩkoragwo na ũkinyanĩru mũno ũhoro-inĩ wĩgiĩ namba. Kwa ngerekano, mũigana wa andũ arĩa magwatĩtio mũrimũ mũna.']
['Hingo ciothe caria ũtaaro wa ndagĩtarĩ kana mũndũ ũngĩ wagĩrĩire ũgima-inĩ waku wa mwĩrĩ igũrũ rĩgiĩ mũrimũ. Ndũkaanahũthie ũtaaro wa ndagĩtarĩ kana ũcererũo kũũcaria nĩ ũndũ wa ũndũ ũthomete thĩinĩ wa website ĩno. Ũngĩkorũo ũrona ta wacemania na ũndũ mũhiũ, hũra thimũ 911 kana ũthiĩ thibitarĩ ya hakuhĩ na harĩa ũrĩ. Gũtirĩ ũrata wa ndagĩtarĩ na mũrwaru wonekaga nĩ ũndũ wa website ĩno kana kũhũthĩrũo kwayo. BioMedLib kana aruti ayo a wĩra, kana mũndũ ũngĩ wothe ũrutĩte wĩra thĩinĩ wa website ĩno, ndarĩ na ũira, wa ĩmwe kwa ĩmwe kana wa ĩmwe kwa ĩmwe, wĩgiĩ ũhoro ũrĩa ũheanĩtwo ho kana ũrĩa ũhũthĩrĩtwo.']
['Ũregani: wĩyathi wa kwandĩka']
['Watho wa Digital Millennium Copyright Act wa 1998, 17 U.S.C. § 512 (the DMCA) ũheanaga ũhoti wa ene a ihoto cia wandĩki arĩa metĩkĩtie atĩ ũhoro ũrĩa ũroneka intanetiinĩ nĩ ũtharĩtie ihooto ciao kũringana na watho wa U.S. wa ihoto cia wandĩki.']
['Ũngĩkorũo na wĩtĩkio atĩ ũhoro kana kĩndũ kĩna gĩtahingũrĩtwo ũhoro-inĩ wĩgiĩ website kana ũtungata witũ nĩ gĩgũthũkia ihooto ciaku, wee (kana mũndũ ũrĩa ũgũgũthondekera) no ũtũtũmĩre notithi ũkĩũria ũhoro kana kĩndũ kĩu kĩeherio, kana ũrigĩrĩrio ndũgacihũthĩre.']
["Marũa macio magĩrĩire gũtũmwo na njĩra ya kwandĩkwo na e-mail (rora ũhoro wa andirethi gĩcunjĩinĩ kĩa 'Maũndũ ma kwaranĩria')."]
['DMCA ĩbataraga atĩ notithi yaku ya kuuna ihooto cia wandĩki ĩkorwo na ũhoro ũyũ: (1) ũtaarĩria wa wĩra ũrĩa ũrĩ na ihooto cia wandĩki ũrĩa ũrarumwo; (2) ũtaarĩria wa ũhoro ũrĩa ũrarumwo na ũhoro mũiganu wa gũtũhotithia kũmenya kũrĩa ũhoro ũcio ũrĩ; (3) ũhoro waku wa kwaranĩria, hamwe na andirethi, namba ya thimũ na andirethi ya e-mail; (4) ndũmĩrĩri yaku atĩ wĩ na wĩtĩkio mwega atĩ ũhoro ũcio ũramenererio ndũrĩ na rũtha rwa mwene wa watho, kana mũrũgamĩrĩri, kana rwa watho o wothe; ']
['(5) nĩ mwandĩkanĩire, na nĩ mũkũheo mũkaana wa kũheenania, atĩ ũhoro ũrĩa ũrĩ kĩmenyithiainĩ kĩu nĩ wa ma na atĩ mũrĩ na ũhoti wa kũhingia ihooto iria mũreganĩte nacio;']
['na (6) kĩrore kĩa mwene kĩhoto kana kĩa mũndũ wĩtĩkĩritio gwĩtongoria handũ ha mwene kĩhoto.']
['Kwaga kwandĩka ũhoro ũcio wothe no gũtũme gũtangĩka gwaku kũhĩtũke.']
['Ũhoro wa Kwaranĩria']
['Tũma ndũmĩrĩri ya kũbucia kũgerera thimũ kana thimũ ya mohoro.']
How is alzheimer diagnosed?
Alzheimer's disease is diagnosed through a combination of methods, including a thorough medical evaluation, cognitive and neuropsychological tests, brain imaging, and the process of elimination of other possible causes.
1. Medical evaluation: A doctor will perform a physical examination and take a detailed medical history to rule out other possible causes of memory loss or cognitive decline, such as thyroid problems, vitamin deficiencies, or brain tumors.
2. Cognitive and neuropsychological tests: These tests assess memory, language, problem-solving, and other cognitive functions to determine the extent of cognitive impairment and to differentiate between normal age-related memory loss and dementia.
3. Brain imaging: Magnetic resonance imaging (MRI) or computed tomography (CT) scans can help identify structural changes in the brain that may indicate Alzheimer's disease.
Positron emission tomography (PET) scans can also be used to measure the levels of certain proteins associated with Alzheimer's disease.
4. Blood tests: Recent research has shown that certain blood tests can help diagnose Alzheimer's disease by measuring the levels of specific proteins or biomarkers associated with the disease.
5. Process of elimination: Since there is no single definitive test for Alzheimer's disease, diagnosis often involves ruling out other possible causes of dementia-like symptoms.
It is important to note that a definitive diagnosis of Alzheimer's disease can only be made after death through an examination of brain tissue.
However, current diagnostic methods can provide a high level of certainty for a clinical diagnosis while the person is still alive.
Early diagnosis is important for starting treatment and planning for the future.
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