What is pathophysiology of Heart attack?

['Tega amatwi iyi paji']

Ni iyihe mikorere y'umutima ku ndwara z'umutima?

Imikorere y'umutima, izwi kandi nka infarctus y'umutima, ikubiyemo guhagarika amaraso agera mu gice cy'umutima, bigatuma uturemangingo tw'umutima dupfa.

Ibi bikunze kubaho bitewe no gufunga kw'imiyoboro y'amaraso y'umutima biturutse ku kuvura kw'amaraso, akenshi biterwa n'indwara yo kwifunga kw'imitsi y'amaraso, indwara ituma mu mitsi y'amaraso habamo ibinure byinshi.

Iyo myanda igizwe na cholesterol, ibintu birimo ibinure, imyanda yo mu ngirabuzimafatizo, kalisiyumu na fibrine.

Iyo plaque isatuye, ishobora gutuma habaho kuvura kw'amaraso, bishobora gufunga imijyana y'amaraso bigatuma amaraso akungahaye kuri ogisijeni atagera mu mitsi y'umutima.

Uku kubura umwuka bituma uturemangingo tw'umutima dupfa, bigatuma umuntu afatwa n'indwara y'umutima.

Uburyo ibyo bikomere bifata bitewe n'aho utwo duce tw'amaraso duherereye, n'igihe gishize hagati y'igihe umurwayi aba afite icyo kibazo n'igihe avurirwa.

Ibimenyetso by'indwara y'umutima bishobora kuba ari ububabare cyangwa kumva utameze neza mu gatuza, guhumeka nabi, kugira isesemi, kugira isereri, no kubabara mu maboko, mu ijosi, mu rwasaya cyangwa mu mugongo.

Ubusanzwe, kuvura indwara y'umutima bisaba ko amaraso asubira mu ngingo z'umutima vuba uko bishoboka kose, byaba binyuze mu miti cyangwa mu kubaga imiyoboro y'amaraso.

Ni ngombwa kumenya ko indwara z'umutima ziterwa n'ibintu byinshi kandi harimo n'ibikomoka ku ngirabuzimafatizo, imibereho n'ibidukikije.

Mu bishobora gutera indwara y'umutima harimo umuvuduko ukabije w'amaraso, kugira ibinure byinshi mu mubiri, kunywa itabi, diyabete, umubyibuho ukabije, kudakora imyitozo ngororangingo no kuba mu muryango w'umuntu hari uwigeze kurwara umutima.

Gucunga ibyo bintu bishobora gutuma umuntu atagira ikibazo cy'umutima.

['Ibitabo']

PubMed/Medline https://www.nlm.nih.gov/databases/download/pubmed_medline.html

RefinedWeb https://arxiv.org/abs/2306.01116

Scott J: Pathophysiology and biochemistry of cardiovascular disease. Curr Opin Genet Dev. 2004, 14 (3): 271-9.

Liu Chung Ming C, Sesperez K, Ben-Sefer E, Arpon D, McGrath K, McClements L, Gentile C: Considerations to Model Heart Disease in Women with Preeclampsia and Cardiovascular Disease. Cells. 2021, 10 (4): .

Hansen J, Victor RG: Direct measurement of sympathetic activity: new insights into disordered blood pressure regulation in chronic renal failure. Curr Opin Nephrol Hypertens. 1994, 3 (6): 636-43.

LaMacchia JC, Roth MB: Aquaporins-2 and -4 regulate glycogen metabolism and survival during hyposmotic-anoxic stress in Caenorhabditis elegans. Am J Physiol Cell Physiol. 2015, 309 (2): C92-6.

Tham YK, Bernardo BC, Ooi JY, Weeks KL, McMullen JR: Pathophysiology of cardiac hypertrophy and heart failure: signaling pathways and novel therapeutic targets. Arch Toxicol. 2015, 89 (9): 1401-38.

Lonn E: The clinical relevance of pharmacological blood pressure lowering mechanisms. Can J Cardiol. 2004, 20 Suppl B (): 83B-88B.

['Icyitonderwa: ubuvuzi']

["Uru rubuga rwashyiriweho kwigisha abantu no kubaha amakuru gusa, ntirutanga inama ku birebana n'ubuvuzi cyangwa ngo rukore nk'ikigo gitanga serivisi z'ubuvuzi."]

["Amakuru atangwa n'iyi porogaramu ntagomba gukoreshwa mu gusuzuma cyangwa kuvura ikibazo cy'uburwayi cyangwa indwara runaka, kandi abashaka inama z'ubuvuzi bagombye kugisha inama umuganga ubifitiye uburenganzira."]

['Nyamuneka menya ko imbuga nkoranyambaga zitanga ibisubizo kubibazo, ntabwo zifite ukuri mugihe kijyanye numubare. Kurugero, umubare wabantu basanzwemo indwara runaka.']

["Buri gihe ujye usaba inama umuganga wawe cyangwa undi muntu wemewe mu bijyanye n'ubuzima ku bijyanye n'uburwayi. Ntuzigere wirengagiza inama z'abaganga cyangwa ngo utinde kuzisaba bitewe n'ikintu wasomye kuri uru rubuga. Niba utekereza ko ufite ikibazo cyihutirwa, hamagara 911 cyangwa ujye ku ivuriro rikwegereye. Nta mubano hagati y'umuganga n'umurwayi ukorwa n'uru rubuga cyangwa ikoreshwa ryarwo. Yaba BioMedLib cyangwa abakozi bayo, cyangwa undi muntu wese wagize uruhare kuri uru rubuga, nta gihamya batanga, yaba igaragara cyangwa itagaragara, ku bijyanye n'amakuru atangwa hano cyangwa ikoreshwa ryayo."]

["Ibirego: uburenganzira bw'umuhanzi"]

["Itegeko ryo mu 1998 ryerekeye uburenganzira bw'ibihumbi by'ibihumbi by'ibihumbi by'ibihumbi, 17 U.S.C. § 512 (DMCA) ritanga ubujurire ku bafite uburenganzira bw'umuhanzi bemera ko ibintu bigaragara kuri interineti bibangamira uburenganzira bwabo hakurikijwe amategeko y'uburenganzira bw'umuhanzi muri Amerika. "]

['Niba wemera ko ibintu cyangwa ibikoresho byashyizwe ku rubuga rwacu cyangwa serivisi bitubahiriza uburenganzira bwawe, wowe (cyangwa umuhagarariye) ushobora kutwoherereza ubutumwa udusaba ko ibyo bintu cyangwa ibikoresho bikurwaho, cyangwa ko utabikoresha.']

['Itangazo rigomba koherezwa mu nyandiko kuri interineti (reba ahanditse "Kwitaba" kugira ngo ubone aderesi ya interineti). ']

["DMCA isaba ko imenyesha ryawe ry'ikirego cyo kuvutswa uburenganzira rikubiyemo amakuru akurikira: (1) ibisobanuro by'igikorwa kirengera uburenganzira bw'umuhanzi kivugwaho kuvutswa uburenganzira; (2) ibisobanuro by'ibikubiyemo bivugwa ko ari ukurenga ku mategeko n'amakuru ahagije atuma dushobora kubona ibikubiyemo; (3) amakuru yo kuguhamagaraho, harimo aderesi yawe, nomero ya terefone na aderesi imeyiri; (4) inyandiko yawe ivuga ko ufite icyizere ko ibikubiyemo mu buryo bwatanzwe nta burenganzira bifite na nyiri uburenganzira bw'umuhanzi, cyangwa umukozi we, cyangwa mu mategeko ayo ari yo yose; "]

["(5) inyandiko yawe isinyweho, uhanishwa kubeshya, yemeza ko amakuru ari mu itangazo ari ukuri kandi ko ufite ububasha bwo kurengera uburenganzira bw'umuhanzi uvugwaho kubwamburwa; "]

["kandi (6) umukono usanzwe cyangwa wa elegitoroniki w'ufite uburenganzira ku nyandiko cyangwa uw'umuntu wabiherewe uburenganzira bwo gukora mu izina ry'ufite uburenganzira ku nyandiko. "]

['Kudatanga amakuru yose yavuzwe haruguru bishobora gutuma ikibazo cyawe gitinda gukemurwa.']

['Uko twavugana na we']

['Ohereza imeri ikibazo / igitekerezo.']

What is pathophysiology of heart attack?

The pathophysiology of a heart attack, also known as myocardial infarction, involves the disruption of blood flow to a part of the heart muscle, leading to the death of heart cells.

This typically occurs due to the obstruction of a coronary artery by a blood clot, which is often the result of atherosclerosis, a condition where plaque builds up in the arteries.

The plaque is made up of cholesterol, fatty substances, cellular waste products, calcium, and fibrin.

When a plaque ruptures, it can cause a blood clot to form, which can block the artery and prevent oxygen-rich blood from reaching the heart muscle.

This lack of oxygen causes the heart muscle cells to die, leading to a heart attack.

The extent of the damage depends on the size of the area supplied by the blocked artery and the time between the attack and treatment.

Symptoms of a heart attack can include chest pain or discomfort, shortness of breath, nausea, lightheadedness, and pain in the arms, neck, jaw, or back.

Treatment for a heart attack usually involves restoring blood flow to the heart muscle as quickly as possible, either through medication or procedures such as angioplasty and stenting or coronary artery bypass surgery.

It is important to note that the pathophysiology of a heart attack is complex and involves multiple factors, including genetic, lifestyle, and environmental factors.

Risk factors for heart attack include high blood pressure, high cholesterol, smoking, diabetes, obesity, lack of physical activity, and a family history of heart disease.

Managing these risk factors can help reduce the likelihood of experiencing a heart attack.

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