What is pathophysiology of Lung cancer?

['Wande ruwu adǝ fanne']

Abi shima physiology kwasa kansabe be wo?

Pathophysiology kwasa kansabe buye faltǝdǝ suro awowa tiyi tibe kǝndǝga-a kuru duluwuwa shido suro kǝndǝga kansabe-a kuru fuwutǝwunzǝben wajin ma.

Kwasa kansabe bube dә kasuwa do suro kәrәngayen wurajin kuru yaktәnzә do noatәnyi ma suwudin.

Cellwa anyi tumour tandoro kuru nashawa tiyebe gade ro tartin, alamawa-a kaziyiwa-a kada suwudin.

Pathophysiologydo kwasa kansabe kasam lan awowa kada suronzǝn mbeji, genetic mutations a, environmental factors a, kuru lifestyle choices a.

Jinbe nəmmbejinzədə faltə DNAbedə suro cell done kəndaramnzən wajin shidoy suro cell done alaubedəa yakcinmadəro suwudin.

Nǝm gade donyi tiyi lan dǝ waratazai awu tiyin lan tuwondiya, kuru adǝ ye sawu kusunyi karabe, alama tawa so, radon so, asbestos so, awu kasam donyi zauro bannajin ma.

Lung cancer dǝ kala indi ro yaktin: small cell lung cancer (SCLC) -a kuru non-small cell lung cancer (NSCLC). NSCLC dǝ waltǝ sana yakkǝro yakkata: adenocarcinoma, squamous cell carcinoma, kuru large cell carcinoma.

Pathophysiologydo jili kwasuwa kansabe anyibedǝ gadejin, dalilnzǝdǝ sandi dǝ jinwa gade-gade mbeji kuru kurunro jawawunza gade.

Pathophysiologydo kwasa kansabe kansa surobedǝ ye kǝndaram kate selwa kansabe-a kuru shido kǝltayinma, suroladǝn nizam kǝrǝntanobe-a.

Cellwa kansabe raksa nizam tiyi adamganabe yitagatciwo, adəye kolzə wurazayin kuru tartin.

Kuru adəgaima, na doni tumourdə dagəna madə, raksə tumourbe wurazə kuru metastasis a so suwudin.

Pathophysiology kwasuwa kansabe bube dә zauro tuskata kuru ngәwuzәyin, kuru kulashiwu soye cidazaiyya sadin duluwuwa shiro cindә asutu kuttuwaro kurunwa dunowa tandoro kuru futu kwasuwa soye kaltәyin ngalwotәgәro.

['Wutəgə']

PubMed/Medline https://www.nlm.nih.gov/databases/download/pubmed_medline.html

RefinedWeb https://arxiv.org/abs/2306.01116

Li Z, Qian Y, Li W, Liu L, Yu L, Liu X, Wu G, Wang Y, Luo W, Fang F, Liu Y, Song F, Cai Z, Chen W, Huang W: Human Lung Adenocarcinoma-Derived Organoid Models for Drug Screening. iScience. 2020, 23 (8): 101411.

Nurwidya F, Syahruddin E, Yunus F: Pain management in lung cancer. Adv Respir Med. 2016, 84 (6): 331-336.

Khan KA, Kennedy MP, Moore E, Crush L, Prendeville S, Maher MM, Burke L, Henry MT: Radiological characteristics, histological features and clinical outcomes of lung cancer patients with coexistent idiopathic pulmonary fibrosis. Lung. 2015, 193 (1): 71-7.

Paramanantham A, Asfiya R, Das S, McCully G, Srivastava A: Extracellular Vesicle (EVs) Associated Non-Coding RNAs in Lung Cancer and Therapeutics. Int J Mol Sci. 2022, 23 (21): .

Lee D, Kim Y, Chung C: Scientific Validation and Clinical Application of Lung Cancer Organoids. Cells. 2021, 10 (11): .

Mucchietto V, Crespi A, Fasoli F, Clementi F, Gotti C: Neuronal Acetylcholine Nicotinic Receptors as New Targets for Lung Cancer Treatment. Curr Pharm Des. 2016, 22 (14): 2160-9.

['Kәlanzәma ro cistәgә: liita']

['Websayit adә ilmu matәbe-a bayan matәbe bas nankaro cedo kuru shawari liyitabe au cidawa cidawu liyitabe diobe gәnyi.']

['Bayanwa yitagattәgәna so dә kwasa laa au kwasa laa asutu au kurun dio ro faidatәmba, kuru am doni shawaria liyitaye mazayin so dә dokta lasisatәna ro manatә saadin.']

['Martәne netәram kәrәnbe do korowa dә ro jawawu suwudin dә, taganasmaro kalkal gәnyi sa lamba isәna dәn. Misallo, nәm nguwu am doni kwasa laa taganasbe shiro asuzana ma.']

["Sambi so ro shawari kam litari nәm au kam gade nasha nәlewabe nozәna ma ye la'atar ro matәne. Shawari kam litaribe nozәna ma ro tәmmaro hangal gәnyi gәnane au sha matә lan loktu gozәnyi awo laa website adәn kәrәnәmma yen. Nyiye kurun nәlewabe batәrammin maa, talfon 911 lan buwoze au njim liwalabe karungu ma ro lenәme. Alaka nәlewa-a dondibe ba ma tuwandin web site adә men au shilan faidatәmen. BioMedLib-a cidawunzә-a, au kam do web site adә ro banazәyin-aye, affima bayanzәna au manazәna ma sadimba, bayanwa suro adәben tuwandin au shilan faidatәmen."]

['Kәlanzәma ro cistәgә: hakku']

['Digital Millennium Copyright Act 1998 17 U.S.C. § 512 (DMCA) dəye am doni hakku kakkadə baksanasodəga nzəliwo sədinma kəla awo lardə U.S.be kərma kakkadə baksəna dəga internet lan fəletəma nzəliwo nankaro.']

['Suro nәm kәla nәm ngәla yen awo laa au kare laa kәla intanetndeyen au cidawandeyen mbejiye hakku nәm kakkadi ruotәbe nyiro kalzәna ma ye mbeji maa, nyi (au wakkilnәm) andero watiya zuwune awo au kare dә tutuluwu, au na dәro nazәgә dә tutuluwu.']

["Zande so dә ruwo lan zuzaiya, email men (adәretәm emailye dә nasha 'Lam'atarro manәmin)"]

['DMCA ye məradənzə bayan kəla nzətkawo kərmaabedəbe bayanwa anyi surodən mbejiro: (1) bayan kəla cida nzətkawobe dunonzə dunonzə kaltəgəbe dunonzə kaltəgəbe; (2) bayan kəla awoa zortəbe dunonzə kaltəgəbe dunonzə kuru bayan kəzəkə andeya səkə awoadəga fandəmin; (3) bayan kəlanəm lamba fantəbe, suro nzəranəm-a, lamba telehonbe-a kuru email-be-a; (4) bayan kəlanəmbe kəla nyiye tawatkənənde kəla awoa zortəbe dunonzə kaltəgəbe dunonzəye dunonzəye səkə au wakilinzəye, au shara laabe səkə; ']

['(5) bayan nyima, kalima jirebero, ruwotәgәna, bayan suro watiyade dә kalkalzәna kuru nyiye hakku kәlanzәbe hakkuwa ləbtәma soye warmatәgәbe dәga nonәmma;']

['kuru (6) mukko dunowa au lantarkibe hakkiwa ləbtamabe au kam laaye wakil zəben cida sədənabe. ']

['Bayanna samibe samma kәltәgә nyiye mowonzә zәktә lamar buruwunәmye gәrәmin.']

['Lǝtǝram']

['Martәne ande ro watiya emailye lan koro/shawari laa manane.']

What is pathophysiology of lung cancer?

The pathophysiology of lung cancer refers to the changes in the normal physiological processes and mechanisms that occur in the development and progression of lung cancer.

Lung cancer is a complex disease that arises from the uncontrolled growth and division of abnormal cells in the lungs.

These cells can form tumors and spread to other parts of the body, leading to various symptoms and complications.

The pathophysiology of lung cancer involves several factors, including genetic mutations, environmental factors, and lifestyle choices.

Genetic mutations can occur in the DNA of lung cells, leading to uncontrolled cell growth and division.

These mutations can be inherited or acquired, and they can be caused by exposure to carcinogens, such as tobacco smoke, radon, asbestos, and air pollution.

Lung cancer can be classified into two main types: small cell lung cancer (SCLC) and non-small cell lung cancer (NSCLC). NSCLC is further divided into three subtypes: adenocarcinoma, squamous cell carcinoma, and large cell carcinoma.

The pathophysiology of these types of lung cancer can differ, as they have different genetic mutations and respond differently to treatment.

The pathophysiology of lung cancer also involves the interaction between cancer cells and the surrounding tissue, including the immune system.

Cancer cells can evade the immune system, allowing them to grow and spread unchecked.

Additionally, the tumor microenvironment can promote tumor growth and metastasis by providing a supportive environment for cancer cells.

The pathophysiology of lung cancer is a complex and dynamic process, and researchers are continuously working to better understand the underlying mechanisms to develop more effective treatments and improve patient outcomes.

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