What are the risk factors for Alzheimer?

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Wie waere es mit demenz?

D'r zien versjèllende risicofactoren veur de ziekte vaan Alzheimer, boe-oonder:

1. Laeftied: 't Risico op 't oontwikkele vaan Alzheimer kump mèt de laeftied touw, de mieste lui weure nao 65 jaor gediagnosticeerd.

2. Genetica: 'n Familiegesjiedenis vaan Alzheimer höbbe of 't drage vaan bepaolde gene, wie 't APOE-e4-gen, kin 't risico op 't oontwikkele vaan de krenkde vergroete.

3. Hoofletsel: 'n Gesjiedenis vaan zwoer hooftrauma of mierdere hersesjtörminge kin 't risico op Alzheimer ziekte vergroete.

4. Hart- en vaatziekte: Aandoeningen die 't hart en de bloodvaten beïnvloede, wie hoeg bloeddruk, hoeg cholesterol, diabetes en euvergewich, kinne 't risico op Alzheimer vergroete.

5. Leefstijlfactoren: Rouke, euvermatig alcoholgebruuk en gebrek aon lichameleke oefening kinne 't risico op Alzheimer ziekte vergroete.

6. Cognitieve inactiviteit: 'n Gebrek aon mentale stimulatie en 'n lieg niveau vaan oonderwies kin 't risico op Alzheimer ziekte vergroete.

7. Slaopstoornisse: Slaopstoornisse, wie slaapapneu, kinne 't risico op Alzheimer ziekte vergroete.

8. Psychologische factore: Depressie, stress en sociaal isolemint kinne 't risico op Alzheimer ziekte vergroete.

't Is belangriek te merke dat 't höbbe vaan ein of mie vaan dees risicofactoren neet per se beteikent dat 'n persoen de ziekte vaan Alzheimer zal oontwikkele, en sommege lui mèt gein bekinde risicofactoren kinne de ziekte toch oontwikkele.

't Begriepe vaan dees risicofactoren kin individue evels helpe stappe te numme um hun risico te vermindere en de gezoondheid vaan de hersene te bevordere.

['Verwiezinge']

PubMed/Medline https://www.nlm.nih.gov/databases/download/pubmed_medline.html

RefinedWeb https://arxiv.org/abs/2306.01116

Borenstein AR, Copenhaver CI, Mortimer JA: Early-life risk factors for Alzheimer disease. Alzheimer Dis Assoc Disord. , 20 (1): 63-72.

Pansari K, Gupta A, Thomas P: Alzheimer's disease and vascular factors: facts and theories. Int J Clin Pract. 2002, 56 (3): 197-203.

Kivipelto M, Helkala EL, Laakso MP, Hänninen T, Hallikainen M, Alhainen K, Iivonen S, Mannermaa A, Tuomilehto J, Nissinen A, Soininen H: Apolipoprotein E epsilon4 allele, elevated midlife total cholesterol level, and high midlife systolic blood pressure are independent risk factors for late-life Alzheimer disease. Ann Intern Med. 2002, 137 (3): 149-55.

Skoog I, Kalaria RN, Breteler MM: Vascular factors and Alzheimer disease. Alzheimer Dis Assoc Disord. , 13 Suppl 3 (): S106-14.

Bidzan L: [Initial symptoms and risk factors in Alzheimer's dementia]. Psychiatr Pol. , 28 (2): 207-19.

Gorelick PB: Risk factors for vascular dementia and Alzheimer disease. Stroke. 2004, 35 (11 Suppl 1): 2620-2.

Kummer BR, Diaz I, Wu X, Aaroe AE, Chen ML, Iadecola C, Kamel H, Navi BB: Associations between cerebrovascular risk factors and parkinson disease. Ann Neurol. 2019, 86 (4): 572-581.

Luchsinger JA, Reitz C, Honig LS, Tang MX, Shea S, Mayeux R: Aggregation of vascular risk factors and risk of incident Alzheimer disease. Neurology. 2005, 65 (4): 545-51.

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What are the risk factors for alzheimer?

There are several risk factors for Alzheimer's disease, including:

1. Age: The risk of developing Alzheimer's disease increases with age, with most people being diagnosed after the age of 65.

2. Genetics: Having a family history of Alzheimer's disease or carrying certain genes, such as the APOE-e4 gene, can increase the risk of developing the disease.

3. Head injury: A history of severe head trauma or multiple concussions may increase the risk of Alzheimer's disease.

4. Cardiovascular health: Conditions that affect the heart and blood vessels, such as high blood pressure, high cholesterol, diabetes, and obesity, may increase the risk of Alzheimer's disease.

5. Lifestyle factors: Smoking, excessive alcohol consumption, and lack of physical exercise may increase the risk of Alzheimer's disease.

6. Cognitive inactivity: A lack of mental stimulation and low levels of education may increase the risk of Alzheimer's disease.

7. Sleep disorders: Sleep disorders, such as sleep apnea, may increase the risk of Alzheimer's disease.

8. Psychological factors: Depression, stress, and social isolation may increase the risk of Alzheimer's disease.

It is important to note that having one or more of these risk factors does not necessarily mean that a person will develop Alzheimer's disease, and some people with no known risk factors may still develop the disease.

However, understanding these risk factors can help individuals take steps to reduce their risk and promote brain health.

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