How is Prostate cancer diagnosed?

['Yoká lokasa oyo']

Ndenge nini bayebaka ete moto azali na kanser ya prostate?

Mpo na koyeba soki ozali na kanser ya prostate, basalaka yo baekzamɛ mpe balolenge mosusu ya kosalisa nzoto, na ndakisa:

1. Kosala ekzame ya prostate na misapi: Monganga akotya mosapi na ye na kati ya estoma mpo na komona soki ezali na mbeba.

2. Test ya antigène prostatique (PSA): Ezali ekzame ya makila oyo emonisaka soki proteini oyo prostate ebimisaka ezali mingi to te.

Soki motángo ya PSA emati, yango ekoki komonisa ete ozali na kanser ya prostate.

3. Ekzamɛ ya échographie transrectale (TRUS): Esɛngaka kotya mwa aparɛyi moko na kati ya estoma mpo na kozwa fɔtɔ ya prostate na lisalisi ya lolaka.

Yango ekoki kosalisa mpo na koyeba soki prostate ezali malamu te.

4. Biopsie: Bakolongola mwa ndambo ya prostate mpe bakotala yango na mikroskope mpo na koyeba soki ezali na baselile ya kanser.

Yango ezali lolenge bobele moko ya koyeba mpenza soki moto azali na kanser ya prostate.

5. Télémétrie par résonance magnétique (IRM): Télémétrie par résonance magnétique ya prostate ekoki kosalisa na koyeba soki ezali na mbeba mpe ekoki kosalisa na koyeba ndenge ya kosala biopsie.

6. Komeka ba gènes: Minganga mosusu bakoki kosalela ba gènes mpo na koyeba soki kanser ezali makasi to te mpe kosalisa moto azwa ekateli ya malamu.

7. Esika oyo mikuwa ezali: Esika oyo mikuwa ezali ekoki mpe kotalelama mpo na koyeba soki kanser ekómi tii na mikuwa.

8. Tomographie par ordinateur (CT): Tomographie par ordinateur ekoki kosalisa mpo na koyeba soki kanser epalangani na binama mosusu to na biteni mosusu ya nzoto.

Ezali na ntina koyeba ete mibali nyonso te oyo bazali na PSA ya likolo to na DRE ya mabe bakozala na kanser ya prostate, mpe kanser nyonso ya prostate ekomema PSA ya likolo te.

Yango wana, esengeli kosala biopsie mpo na koyeba soki maladi yango ezali mpenza.

Lisusu, ekateli ya kosala biopsie ezwamaka nsima ya kotalela makambo oyo emonani na baekzame yango mpe makambo oyo ekoki kosala ete moto azwa maladi yango mpe makambo oyo akolinga.

['Makambo oyo ezali na buku yango']

PubMed/Medline https://www.nlm.nih.gov/databases/download/pubmed_medline.html

RefinedWeb https://arxiv.org/abs/2306.01116

Saldova R, Fan Y, Fitzpatrick JM, Watson RW, Rudd PM: Core fucosylation and alpha2-3 sialylation in serum N-glycome is significantly increased in prostate cancer comparing to benign prostate hyperplasia. Glycobiology. 2011, 21 (2): 195-205.

Marenco J, Kasivisvanathan V, Emberton M: New standards in prostate biopsy. Arch Esp Urol. 2019, 72 (2): 142-149.

Moradi M, Mousavi P, Abolmaesumi P: Computer-aided diagnosis of prostate cancer with emphasis on ultrasound-based approaches: a review. Ultrasound Med Biol. 2007, 33 (7): 1010-28.

Cuperlovic-Culf M, Belacel N, Davey M, Ouellette RJ: Multi-gene biomarker panel for reference free prostate cancer diagnosis: determination and independent validation. Biomarkers. 2010, 15 (8): 693-706.

McGrath SE, Michael A, Morgan R, Pandha H: EN2: a novel prostate cancer biomarker. Biomark Med. 2013, 7 (6): 893-901.

An Y, Chang W, Wang W, Wu H, Pu K, Wu A, Qin Z, Tao Y, Yue Z, Wang P, Wang Z: A novel tetrapeptide fluorescence sensor for early diagnosis of prostate cancer based on imaging Zn2+ in healthy versus cancerous cells. J Adv Res. 2020, 24 (): 363-370.

[Consensus of Chinese experts on the application of molecular imaging targeting prostate specific membrane antigen in prostate cancer patients]. Zhonghua Wai Ke Za Zhi. 2018, 56 (2): 91-94.

Zhong WD, He HC, Bi XC, Ou RB, Jiang SA, Liu LS: cDNA macroarray for analysis of gene expression profiles in prostate cancer. Chin Med J (Engl). 2006, 119 (7): 570-3.

['Koboya: makambo ya monganga']

['Site oyo ezali kaka mpo na koteya mpe koyebisa bato makambo ya monganga, kasi ezali te mpo na kopesa toli to toli ya monganga.']

['Makambo oyo ezali na site yango esengeli te kosalelama mpo na koyeba maladi to kosalisa yango, mpe baoyo balingi kozwa toli ya monganga basengeli kotuna yango epai ya monganga oyo ayebi mosala yango malamu.']

['Tosengi na yo oyeba ete réseau neuronal oyo epesaka biyano na mituna, ezalaka mpenza malamu te soki ezali na makambo ya mituya. Na ndakisa, motango ya bato oyo bazali na maladi moko boye.']

['Sololá ntango nyonso na monganga to na moto mosusu oyo ayebi kosalisa maladi na yo. Koboya toli ya monganga te to kozela te mpo otángi likambo moko na site oyo. Soki okanisi ete ozali na maladi oyo esengeli kosalisa yo nokinoki, bengá 911 to kende na lopitalo ya pene. Site oyo to ndenge oyo ozali kosalela yango ezali na boyokani te na monganga ná moto oyo azali kosalisa yo.']

["Kozanga ndingisa: droit d'auteur"]

['Mobeko ya Copyright ya Milenere ya 1998, 17 U.S.C. § 512 (DMCA) epesi nzela na bakomi ya mikanda oyo bakanisi ete biloko oyo ezali na Internet ezali kobebisa lotomo na bango na kolanda mibeko ya copyright ya Etats-Unis. ']

['Soki ondimi na motema malamu ete makambo to biloko oyo ezali na site Internet to na ba service na biso ezali kobuka mibeko na yo, yo (to moto oyo azali na mokumba ya kobatela yo) okoki kotindela biso mokanda mpo na kosɛnga ete tólongola makambo to biloko yango to tópekisa yo kokɔta na yango. ']

['Basengeli kotinda bansango na mokanda na nzela ya email (tala na "Kotindelana" mpo na adresse ya email). ']

['Mibeko ya DMCA esengi ete mokanda na yo ya kofunda mbeba ya copyright ezala na makambo oyo elandi: (1) kolimbola mosala oyo ezali na droit ya copyright oyo bazali kofunda ete ebebisami; (2) kolimbola makambo oyo bazali kofunda ete ebebisi mpe makambo oyo ekoki mpo na kosalisa biso na koyeba esika makambo yango ezali; (3) makambo ya kosolola na yo, ata mpe adrɛsi na yo, nimero ya telefone mpe adrɛsi ya e-mail; (4) mokanda oyo okomi ete ondimi na motema malamu ete makambo oyo ozali kofunda ete ebebisami epesami nzela te na nkolo ya droit ya copyright, to na agent na ye, to na mibeko nyonso; ']

['(5) mokanda oyo okomi, oyo okotya sinyatili na yango mpo na komonisa ete makambo oyo okomaki ezali solo mpe ete ozali na lotomo ya kolandela lotomo ya babimisi oyo bazali koloba ete ebebisami; ']

['mpe (6) sinyatili ya moto oyo azali na lotomo ya kosala yango to ya moto oyo azali na lotomo ya kosala na nkombo na ye. ']

['Soki otye makambo nyonso te oyo ezali awa na likolo, yango ekoki kosala ete likambo na yo eumela.']

['Ndenge ya kosolola']

['Tosengi otindela biso email na motuna to likanisi nyonso.']

How is prostate cancer diagnosed?

Prostate cancer is diagnosed through a combination of tests and procedures, which may include:

1. Digital Rectal Exam (DRE): A doctor inserts a gloved, lubricated finger into the rectum to feel the prostate for any abnormalities.

2. Prostate-Specific Antigen (PSA) Test: This is a blood test that measures the level of PSA, a protein produced by the prostate gland.

Elevated PSA levels may indicate the presence of prostate cancer.

3. Transrectal Ultrasound (TRUS): A small probe is inserted into the rectum to create an image of the prostate using sound waves.

This can help identify any abnormalities in the prostate gland.

4. Biopsy: A small sample of prostate tissue is removed and examined under a microscope for the presence of cancer cells.

This is the only definitive way to diagnose prostate cancer.

5. Magnetic Resonance Imaging (MRI): An MRI scan of the prostate can help identify any abnormalities and guide the biopsy procedure.

6. Genomic Testing: Some doctors may use genomic tests to help determine the aggressiveness of the cancer and guide treatment decisions.

7. Bone Scan: A bone scan may be performed to check if the cancer has spread to the bones.

8. Computed Tomography (CT) Scan: A CT scan may be used to check if the cancer has spread to other organs or tissues.

It is important to note that not all men with elevated PSA levels or abnormal DRE results will have prostate cancer, and not all prostate cancers will cause elevated PSA levels.

Therefore, a biopsy is necessary to confirm the diagnosis.

Additionally, the decision to undergo a biopsy is made after considering the results of these tests and the individual's risk factors and preferences.

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