How to treat Prostate cancer?

['Whakarongo ki tēnei whārangi']

Me pēhea te whakaora i te mate pukupuku repeure?

He maha ngā kōwhiringa maimoatanga e wātea ana mō te mate pukupuku repeure, i runga anō i te wāhanga me te kaha o te mate pukupuku, me te hauora whānui me ngā manakohanga whaiaro o te tūroro.

Ko ētahi maimoatanga noa ko:

1. Te mātakitaki kaha: Kei tēnei huarahi te mātakitaki tata i te mate pukupuku mā te tirotiro auau me ngā whakamātautau, kaua ki te tīmata tonu i te maimoatanga.

He pai pea mo nga tane he mate pukupuku prostate iti te mate.

2. Te pokanga: Ko te prostatectomy he mahinga pokanga hei tango i te repe repeure.

Ka taea te mahi mā te pokanga tuwhera, mā te laparoscopically rānei (mā te whakamahi i ngā tapahi iti me ngā taputapu motuhake).

3. Te rongoā irirangi: Ko tenei maimoatanga e whakamahi ana i te kaha nui o te kaha ki te patu i nga pūtau mate pukupuku.

Ka taea te tukuna ki waho (mai i tētahi mīhini i waho o te tinana) ki roto rānei (mā ngā tāpiritanga e whakatakotoria ana ki te taha o te puku).

4. Te rongoā taiaki: Mā tēnei maimoatanga e whakaiti i ngā taumata o ngā taiaki tāne (androgens) i roto i te tinana, e taea ai te pōturi, te whakamutu rānei i te tupu o te mate pukupuku repeure.

Ka taea te whakamahi takitahi, te whakakotahi rānei me ētahi atu maimoatanga.

5. Chemotherapy: Ka whakamahia e tēnei maimoatanga ngā rongoā hei patu i ngā pūtau mate pukupuku.

Ka whakamahia pea mo te mate pukupuku prostate matatau kua horapa ki etahi atu waahanga o te tinana.

6. Immunotherapy: Ko tenei maimoatanga ka awhina i te punaha aukati ki te whawhai i te mate pukupuku.

Ka taea te whakamahi mō te mate pukupuku repeure matatau kāore i urupare ki ētahi atu rongoā.

7. Te maimoatanga kua whaaia: Ko tenei maimoatanga e aro ana ki nga ira motuhake, ki nga pūmua ranei e awhina ana i nga pūtau mate pukupuku kia tipu me te ora.

Ka taea te whakamahi mō te mate pukupuku repeure matatau kāore i urupare ki ētahi atu rongoā.

8. Cryotherapy: Ka whakamahia e tēnei maimoatanga te makariri tino nui hei whakamātao me te patu i ngā pūtau mate pukupuku.

Ka whakamahia pea mo te mate pukupuku prostate i te wa o mua, mo te mate pukupuku ranei kua hoki mai i muri i etahi atu maimoatanga.

9. Te kaha-nui o te ultrasound (HIFU): Ka whakamahia e tenei maimoatanga nga ngaru oro auau-teitei hei whakawera me te whakangaro i nga pūtau mate pukupuku.

Ka whakamahia pea mo te mate pukupuku prostate i te wa o mua, mo te mate pukupuku ranei kua hoki mai i muri i etahi atu maimoatanga.

10. Te tatari mataara: Ko tenei huarahi e pa ana ki te tirotiro i te mate pukupuku me nga tirotiro me nga whakamatautau auau, engari kaua e tiimata te maimoatanga ki te kore e puta nga tohu, ka huri ranei.

He pai pea mo nga kaumatua me te mate pukupuku prostate e tipu haere ana me etahi atu mate hauora kino.

He mea nui kia matapakihia ngā kōwhiringa maimoatanga katoa me tētahi rōpū tiaki hauora hei whakatau i te huarahi pai rawa atu mō ia take.

['Ngā tohutoro']

PubMed/Medline https://www.nlm.nih.gov/databases/download/pubmed_medline.html

RefinedWeb https://arxiv.org/abs/2306.01116

Wang Y, Chen J, Wu Z, Ding W, Gao S, Gao Y, Xu C: Mechanisms of enzalutamide resistance in castration-resistant prostate cancer and therapeutic strategies to overcome it. Br J Pharmacol. 2021, 178 (2): 239-261.

Talkar SS, Patravale VB: Gene Therapy for Prostate Cancer: A Review. Endocr Metab Immune Disord Drug Targets. 2021, 21 (3): 385-396.

Šamija I, Fröbe A: CHALLENGES IN MANIPULATING IMMUNE SYSTEM TO TREAT PROSTATE CANCER. Acta Clin Croat. 2019, 58 (Suppl 2): 76-81.

Akaza H, Hinotsu S, Usami M, Ogawa O, Kagawa S, Kitamura T, Tsukamoto T, Naito S, Hirao Y, Murai M, Yamanaka H, Namiki M: The case for androgen deprivation as primary therapy for early stage disease: results from J-CaP and CaPSURE. J Urol. 2006, 176 (6 Pt 2): S47-9.

Abraham-Miranda J, Awasthi S, Yamoah K: Immunologic disparities in prostate cancer between American men of African and European descent. Crit Rev Oncol Hematol. 2021, 164 (): 103426.

de Vrij J, Willemsen RA, Lindholm L, Hoeben RC, Bangma CH, Barber C, Behr JP, Briggs S, Carlisle R, Cheng WS, Dautzenberg IJ, de Ridder C, Dzojic H, Erbacher P, Essand M, Fisher K, Frazier A, Georgopoulos LJ, Jennings I, Kochanek S, Koppers-Lalic D, Kraaij R, Kreppel F, Magnusson M, Maitland N, Neuberg P, Nugent R, Ogris M, Remy JS, Scaife M, Schenk-Braat E, Schooten E, Seymour L, Slade M, Szyjanowicz P, Totterman T, Uil TG, Ulbrich K, van der Weel L, van Weerden W, Wagner E, Zuber G: Adenovirus-derived vectors for prostate cancer gene therapy. Hum Gene Ther. 2010, 21 (7): 795-805.

Lee E, Ha S, Logan SK: Divergent Androgen Receptor and Beta-Catenin Signaling in Prostate Cancer Cells. PLoS One. 2015, 10 (10): e0141589.

['Whakakahoretanga: hauora']

['Ko tenei paetukutuku e whakaratohia ana mo nga kaupapa ako me nga korero anake, kaore hoki e whakarato i nga tohutohu hauora, i nga ratonga ngaio ranei.']

['Kaua e whakamahia ngā mōhiohio e whakaratohia ana hei tātaritanga, hei whakaora rānei i tētahi raruraru hauora, mate rānei, ā, ko te hunga e rapu ana i te tohutohu hauora whaiaro me kōrero ki tētahi tākuta whai raihana.']

['Kia mōhio mai koe ko te whatunga pūtau e whakaputa ana i ngā whakautu ki ngā pātai, he tino hē ina tae mai ki te ihirangi tau. Hei tauira, ko te tokomaha o ngā tāngata kua tohua he mate tauwhāiti.']

['Me rapu tonu i te tohutohu a tō tākuta, i tētahi atu kaiwhakarato hauora whai tohu rānei e pā ana ki tētahi mate hauora. Kaua rawa e whakahawea ki te tohutohu hauora ngaio, te whakaroa rānei ki te rapu i te mea nā tētahi mea i pānuihia e koe i tēnei paetukutuku. Ki te whakaaro koe he mate hauora ohorere pea koe, waea atu ki te 911 ka haere ki te rūma ohorere tata tonu. Kāore he hononga tākuta-tūroro i hangaia e tēnei paetukutuku, i tōna whakamahinga rānei. Kāore a BioMedLib, ōna kaimahi rānei, tētahi kaitohutohu rānei ki tēnei paetukutuku, e whakaatu ana, e tohu ana rānei, e pā ana ki ngā mōhiohio e whakaratohia ana i konei, ki tōna whakamahinga rānei.']

['Whakakahoretanga: mana pupuri']

['Ko te Ture Mana pupuri Mamati Mamati o te tau 1998, 17 U.S.C. § 512 (te DMCA) e whakarato ana i te whakahoki mo nga rangatira mana pupuri e whakapono ana ko nga rauemi e puta ana i runga i te Ipurangi e takahi ana i o raatau mana i raro i te ture mana pupuri a US. ']

['Mēnā e whakapono pono ana koe e takahi ana tētahi ihirangi, rauemi rānei e wātea ana i runga i tō mātou paetukutuku, ratonga rānei i tō mana pupuri, ka taea e koe (tō māngai rānei) te tuku pānui ki a mātou e tono ana kia tangohia te ihirangi, rauemi rānei, kia āraia rānei te uru atu ki a ia. ']

["Me tuku ngā whakamōhiotanga ā-tuhi mā te īmēra (tirohia te wāhanga 'Whakapā' mō te wāhitau īmēra). "]

['E hiahiatia ana e te DMCA kia whakaurua ki tō whakamōhiotanga mō te whakawātea mana pupuri i ngā mōhiohio e whai ake nei: (1) whakaahuatanga o te mahi mana pupuri e pā ana ki te whakawātea e whakapaetia ana; (2) whakaahuatanga o te ihirangi e whakapaetia ana e takahi ana me ngā mōhiohio e tika ana kia taea ai e mātou te kimi i te ihirangi; (3) mōhiohio whakapā mōu, tae atu ki tō wāhitau, tau waea me tō wāhitau īmēra; (4) he tauākī nāu e whakapono pono ana koe kāore te ihirangi i te āhua e amuamutia ana i whakamanahia e te kaipupuri mana pupuri, e tana māngai rānei, e te whakahaerenga rānei o tētahi ture; ']

['(5) he tauākī nāu i haina, i raro i te whiu o te whakapae teka, e tika ana ngā mōhiohio i roto i te whakamōhiotanga, ā, kei a koe te mana ki te whakatinana i ngā mana pupuri e kīia ana kua takahia;']

['me te (6) he waitohu ā-tinana, ā-rorohiko rānei a te kaipupuri mana pupuri, a tētahi tangata rānei kua whakamanahia ki te mahi mō te kaipupuri mana pupuri. ']

['Ki te kore e whakaurua ngā mōhiohio katoa i runga ake nei, ka whakaroa pea te tukatuka o tō amuamu.']

['Whakapā']

['Tena koa tukuna mai he imeera ki a maatau me tetahi patai / whakaaro.']

How to treat prostate cancer?

There are several treatment options available for prostate cancer, depending on the stage and aggressiveness of the cancer, as well as the patient's overall health and personal preferences.

Some common treatments include:

1. Active surveillance: This approach involves closely monitoring the cancer with regular checkups and tests, rather than immediately starting treatment.

It may be suitable for men with low-risk prostate cancer.

2. Surgery: A prostatectomy is a surgical procedure to remove the prostate gland.

It can be done through open surgery or laparoscopically (using small incisions and specialized tools).

3. Radiation therapy: This treatment uses high-energy radiation to kill cancer cells.

It can be delivered externally (from a machine outside the body) or internally (through implants placed near the tumor).

4. Hormone therapy: This treatment reduces the levels of male hormones (androgens) in the body, which can slow or stop the growth of prostate cancer.

It can be used alone or in combination with other treatments.

5. Chemotherapy: This treatment uses drugs to kill cancer cells.

It may be used for advanced prostate cancer that has spread to other parts of the body.

6. Immunotherapy: This treatment helps the immune system fight cancer.

It may be used for advanced prostate cancer that has not responded to other treatments.

7. Targeted therapy: This treatment targets specific genes or proteins that help cancer cells grow and survive.

It may be used for advanced prostate cancer that has not responded to other treatments.

8. Cryotherapy: This treatment uses extreme cold to freeze and kill cancer cells.

It may be used for early-stage prostate cancer or for cancer that has come back after other treatments.

9. High-intensity focused ultrasound (HIFU): This treatment uses high-frequency sound waves to heat and destroy cancer cells.

It may be used for early-stage prostate cancer or for cancer that has come back after other treatments.

10. Watchful waiting: This approach involves closely monitoring the cancer with regular checkups and tests, but not starting treatment unless symptoms appear or change.

It may be suitable for older men with slow-growing prostate cancer and other serious health conditions.

It is important to discuss all treatment options with a healthcare team to determine the best course of action for each individual case.

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