Pathophysiology ya kankere ya maswafo e šupa diphetogo tša tshepedišo ya tlhago ya mmele le mekgwa yeo e diregago ge go tšwelela le go tšwela pele ga kankere ya maswafo.
Kankere ya maswafo ke bolwetši bjo bo raraganego bjo bo bakwago ke go gola le go arogana mo go sa laolegego ga disele tše di sa tlwaelegago tša maswafo.
Disele tše di ka bopa di-tumor gomme tša phatlalala dikarolong tše dingwe tša mmele, tša baka maswao a fapa-fapanego le mathata.
Pathophysiology ya kankere ya maswafo e akaretša dilo tše mmalwa, go akaretša go fetoga ga leabela, dilo tša tikologo le tsela ya bophelo.
Diphetogo tša leabela di ka direga go DNA ya disele tša maswafo, tša lebiša go go goleng le go aroganeng ga disele mo go sa laolegego.
Diphetogo tše di ka abelwa goba tša hwetšwa, gomme di ka bakwa ke go ba kgauswi le dilo tšeo di bakago kankere, tše bjalo ka muši wa motšoko, radon, asbestos le tšhilafalo ya moya.
Kankere ya maswafo e ka arolwa ka mehuta e mebedi e megolo: kankere ya maswafo ya disele tše dinyenyane (SCLC) le kankere ya maswafo ya disele tše sego tše dinyenyane (NSCLC). NSCLC e arolwa gape ka mehuta e meraro ya ka tlase: adenocarcinoma, squamous cell carcinoma le large cell carcinoma.
Pathophysiology ya mehuta ye ya kankere ya maswafo e ka fapana, ka ge e na le diphetogo tše di fapanego tša leabela gomme e arabela ka tsela e fapanego kalafong.
Pathophysiology ya kankere ya maswafo gape e akaretša go dirišana magareng ga disele tša kankere le dithishu tše di e dikologilego, go akaretša le tshepedišo ya go lwantšha malwetši.
Disele tša kankere di ka kgona go phema tshepedišo ya mmele ya go lwantšha malwetši, tša di dumelela go gola le go phatlalala di sa laolwe.
Go oketša moo, tikologo e nyenyane ya serurugi e ka godiša kgolo ya serurugi le go phatlalala ga sona ka go nea tikologo e thekgago disele tša kankere.
Pathophysiology ya kankere ya maswafo ke tshepedišo e raraganego le e matla, gomme banyakišiši ba šoma ka go se kgaotše go kwešiša gabotse mekgwa ya motheo ya go tšweletša dikalafo tše di šomago gabotse le go kaonefatša mafelelo a balwetši.
Li Z, Qian Y, Li W, Liu L, Yu L, Liu X, Wu G, Wang Y, Luo W, Fang F, Liu Y, Song F, Cai Z, Chen W, Huang W: Human Lung Adenocarcinoma-Derived Organoid Models for Drug Screening. iScience. 2020, 23 (8): 101411.
Nurwidya F, Syahruddin E, Yunus F: Pain management in lung cancer. Adv Respir Med. 2016, 84 (6): 331-336.
Khan KA, Kennedy MP, Moore E, Crush L, Prendeville S, Maher MM, Burke L, Henry MT: Radiological characteristics, histological features and clinical outcomes of lung cancer patients with coexistent idiopathic pulmonary fibrosis. Lung. 2015, 193 (1): 71-7.
Paramanantham A, Asfiya R, Das S, McCully G, Srivastava A: Extracellular Vesicle (EVs) Associated Non-Coding RNAs in Lung Cancer and Therapeutics. Int J Mol Sci. 2022, 23 (21): .
Lee D, Kim Y, Chung C: Scientific Validation and Clinical Application of Lung Cancer Organoids. Cells. 2021, 10 (11): .
Mucchietto V, Crespi A, Fasoli F, Clementi F, Gotti C: Neuronal Acetylcholine Nicotinic Receptors as New Targets for Lung Cancer Treatment. Curr Pharm Des. 2016, 22 (14): 2160-9.
['Boikano: bja tša kalafo']
['Wepesaete ye e neetšwe feela bakeng sa go ruta le go nea tsebišo gomme ga e nee keletšo ya tša kalafo goba ditirelo tša tša kalafo.']
['Tsebišo yeo e neilwego ga se ya swanela go dirišwa bakeng sa go hlahloba goba go alafa bothata bja tša maphelo goba bolwetši, gomme bao ba nyakago keletšo ya tša kalafo ya motho ka noši ba swanetše go boledišana le ngaka yeo e nago le tumelelo.']
['Ka kgopelo lemoga gore netweke ya methapo yeo e tšweletšago dikarabo tša dipotšišo, ga e nepagale kudu ge go tliwa go diteng tša dinomoro. Ka mohlala, palo ya batho bao ba hweditšwego ba na le bolwetši bjo bo itšego.']
['Ka mehla nyaka keletšo ya ngaka ya gago goba mofani yo mongwe wa tlhokomelo ya tša maphelo yo a nago le bokgoni mabapi le boemo bja tša kalafo. Le ka mohla o se ke wa hlokomologa keletšo ya tša kalafo goba wa diega go e nyaka ka baka la selo seo o se badilego wepesaeteng ye. Ge e ba o nagana gore o ka ba o le boemong bja tšhoganetšo bja tša kalafo, leletša 911 goba o ye phapošing ya tšhoganetšo ya kgauswi le wena kapejana. Ga go na tswalano ya ngaka le molwetši yeo e bopšago ke wepesaete ye goba go e diriša. BioMedLib goba bašomi ba yona, goba motho le ge e le ofe yo a tsenyago letsogo wepesaeteng ye, ga ba dire ditshepišo le ge e le dife, e ka ba tše di boletšwego ka go lebanya goba tše di sa hlaloswago gabotse, mabapi le tsebišo yeo e neilwego mo goba go e diriša.']
['Go se tšee karolo: tokelo ya ngwalollo']
['Molao wa Digital Millennium Copyright wa 1998, 17 U.S.C. § 512 (DMCA) o nea baamogedi ba tokelo ya ngwalollo bao ba dumelago gore dilo tšeo di tšwelelago ka go Inthanete di tshwenyana le ditokelo tša bona ka tlase ga molao wa U.S. wa tokelo ya ngwalollo. ']
['Ge e ba o dumela ka potego gore diteng goba dilo tšeo di lego mabapi le wepesaete ya rena goba ditirelo di tshwenyana le tokelo ya gago ya go gatiša, wena (goba moemedi wa gago) o ka re romela tsebišo ya gore o kgopele gore diteng goba dilo tšeo di tlošwe goba gore o thibelwe go di fihlelela. ']
["Ditsebišo di swanetše go romelwa ka go ngwala ka emeile (lebelela karolo ya 'Kgokagano' go hwetša aterese ya emeile). "]
['DMCA e nyaka gore tsebišo ya gago ya go pharwa ga molao wa tokelo ya ngwalollo e akaretše tshedimošo ye e latelago: (1) tlhaloso ya mošomo wa tokelo ya ngwalollo wo o pharwago ka molao wa go pharwa ga molao wa go pharwa ga molao wa go pharwa ga molao wa go pharwa ga molao wa go pharwa ga molao wa go pharwa ga molao wa go pharwa ga molao wa go pharwa ga molao wa go pharwa ga molao wa go pharwa ga molao wa go pharwa ga molao wa go pharwa ga molao wa go pharwa ga molao wa go pharwa ga molao wa go pharwa ga molao wa go pharwa ga molao wa go pharwa ga molao wa go pharwa ga molao wa go pharwa ga molao wa go pharwa ga molao wa go pharwa ga molao wa go pharwa ga molao wa go pharwa ga molao wa go pharwa ga molao wa go pharwa ga molao wa go pharwa ga molao wa go pharwa ga molao wa go pharwa ga molao wa go pharwa ga molao wa go pharwa ga molao wa go pharwa ga molao wa go pharwa ga molao wa go pharwa ga molao wa go pharwa ga molao wa go pharwa ga molao wa go pharwa ga molao wa go pharwa ga molao wa go pharwa ga molao wa go pharwa ga molao wa go pharwa ga molao wa go pharwa ga molao wa go pharwa ga molao wa go pharwa ga molao wa go pharwa ga molao wa go pharwa ga molao wa go pharwa ga molao wa go pharwa ga molao wa go pharwa ga molao wa go pharwa ga molao wa go pharwa ga molao wa go pharwa ga molao wa go pharwa ga molao wa go pharwa ga molao wa go pharwa ga molao wa go pharwa ga molao wa go pharwa ga molao wa go pharwa ga molao wa go pharwa ga molao wa go pharwa ga molao wa go pharwa ga molao wa go pharwa ga molao wa go pharwa ga molao wa go pharwa ga molao wa go pharwa ga molao wa go pharwa ga molao wa go pharwa ga molao wa go pharwa ga molao wa go pharwa ga molao wa go pharwa ga molao wa go pharwa ga molao wa go pharwa ga molao wa go pharwa ga molao wa go pharwa ga molao wa go pharwa ga molao wa go pharwa ga molao wa pharwa ga molao wa pharwa ga molao wa go pharwa ga molao wa pharwa ga molao wa pharwa ga molao wa pharwa ga molao wa pharwa ga molao wa pharwa ga molao wa pharwa ga molao wa pharwa ga molao wa pharwa ga molao wa pharwa ga molao wa pharwa ga molao wa pharwa ga molao wa pharwa ga molao wa pharwa ga molao wa pharwa ga molao wa pharwa ga molao wa pharwa ga molao wa pharwa ga molao wa pharwa ga molao wa pharwa ga molao wa pharwa ga molao.']
['(5) setatamente sa gago, seo se saennwego ka tlase ga kotlo ya go bolela maaka, gore tshedimošo yeo e lego tsebišong e nepagetše le gore o na le maatla a go phethagatša ditokelo tša mongwadi tšeo go thwego di a gatakelwa; ']
['le (6) tshaeno ya kgonthe goba ya elektroniki ya mong wa tokelo ya ngwalollo goba motho yo a dumeletšwego go dira legatong la mong wa tokelo ya ngwalollo. ']
['Go palelwa ke go akaretša tshedimošo ka moka ya ka godimo go ka dira gore go šongwa ga ngongorego ya gago go diege.']
['Go Ikgokaganya']
['Re romele imeile ka kgopelo le ge e le efe goba tšhišinyo.']
What is pathophysiology of lung cancer?
The pathophysiology of lung cancer refers to the changes in the normal physiological processes and mechanisms that occur in the development and progression of lung cancer.
Lung cancer is a complex disease that arises from the uncontrolled growth and division of abnormal cells in the lungs.
These cells can form tumors and spread to other parts of the body, leading to various symptoms and complications.
The pathophysiology of lung cancer involves several factors, including genetic mutations, environmental factors, and lifestyle choices.
Genetic mutations can occur in the DNA of lung cells, leading to uncontrolled cell growth and division.
These mutations can be inherited or acquired, and they can be caused by exposure to carcinogens, such as tobacco smoke, radon, asbestos, and air pollution.
Lung cancer can be classified into two main types: small cell lung cancer (SCLC) and non-small cell lung cancer (NSCLC). NSCLC is further divided into three subtypes: adenocarcinoma, squamous cell carcinoma, and large cell carcinoma.
The pathophysiology of these types of lung cancer can differ, as they have different genetic mutations and respond differently to treatment.
The pathophysiology of lung cancer also involves the interaction between cancer cells and the surrounding tissue, including the immune system.
Cancer cells can evade the immune system, allowing them to grow and spread unchecked.
Additionally, the tumor microenvironment can promote tumor growth and metastasis by providing a supportive environment for cancer cells.
The pathophysiology of lung cancer is a complex and dynamic process, and researchers are continuously working to better understand the underlying mechanisms to develop more effective treatments and improve patient outcomes.
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