How is Alzheimer diagnosed?

Kä Aldhɛimer ba jɛ ŋa̱c i̱di̱?

Alzheimer's disease cua jiek kɛ dup ti̱ ŋuan, amäni̱ thëm in di̱i̱t kä ki̱mikal, ŋieec kɛnɛ thëm neuropsychological, cär ŋithä, kɛnɛ ta̱a̱ in la woc kɛ tin kɔ̱ŋ tin de ji̱ëk.

1. Guäc kɛ gua̱a̱th in te raan thi̱n: Bi̱ ki̱m ji̱ guɔ̱ɔ̱rä ji̱ guic kä bɛ ji̱ guɔ̱ɔ̱rä ku lɛ thiec kɛ kui̱ kä tin ci̱ tuɔɔk ni̱ wal kɛ ɣöö bɛ ji̱ jakä /ci̱kɛ bi̱ cop lɔɔcdu kiɛ bi̱ ŋäcdu wä piny, ce̱tkɛ mi̱ ciee kɛ mi̱ ci̱ riɛk tuɔɔk kɛ thayi̱röyd, mi̱ ci̱ pi̱i̱thtamiin thiɛl, kiɛ mi̱ ci̱ tuɔmri̱ ŋithä wä raar.

2. Kɔnji̱e̱tɛcin kɛnɛ neuropthi̱kölo̱ji̱kal thëmni̱: Kɛn thëmni̱ ti̱ti̱ laa guɛckɛ ti̱e̱e̱c, thok, luäŋ kɛ riali̱ rikni̱, kɛnɛ lät tin kɔ̱ŋ tin ŋa̱ckɛ kɛ kui̱i̱ kä ɣöö baa pek in ci̱ ŋithä jiek ŋa̱c kɛnɛ ɣöö baa dääk in te kam mi̱ ci̱ ŋithä jiek kɛ run kɛnɛ mi̱ ci̱ ŋithä jiek.

3. Guäc ŋithä: Guäc ŋithä mi̱ cɔali̱ Magnetic resonance imaging (MRI) kiɛ kɔmpi̱e̱e̱tɛr tomögi̱ra̱pi̱ (CT) i̱thkanni̱ dɔ̱ŋ bɛ luäk kɛ ɣöö ba ta̱a̱ in tä ŋithä gɛr min bi̱ nyoth ni̱ juey Aldhɛhayma̱r.

Po̱thitron emision tomography (PET) i̱thkanni̱ dɔ̱ŋ bä dëë kɛ la̱t kɛ thëmni̱ pek pröti̱i̱ni̱ tin te kɛɛl kɛ juey Aldhaimera̱th.

4. Kɛn thɛmni̱ riɛm: Rithääc mi̱ pay la̱t nyothɛ jɛ ɛn ɣöö thɛmni̱ riɛm tin kɔ̱ŋ dëë luäk kɛ jiekdɛ kä juey Alzheimer kɛ thëmni̱ pek prötienni̱ tin ca lɛy kiɛ tin nyooth juey.

5.Thiɛl mi̱ dëë ŋa̱c: Kɛ ɣöö thilɛ mi̱ dëë thɛm kɛ kui̱i̱ juey Alzheimer, ba jɛ ŋa̱c kɛ ɣöö te kɛ mi̱ dɔ̱ŋ mi̱ dee jɛ jakä tä kɛ juey mi̱ cie dementia.

Jɛn ɛ mi̱ di̱i̱t ɛn ɣöö ba ŋa̱c ɛn ɣöö juey Alzheimer derɛ tuɔk ni̱ kɛ kɔr li̱eth kɛ guäc pua̱a̱ny.

Duŋdɛ ɣöö, ca̱a̱p thëm in thi̱a̱k ɛ mɛ de luäk kɛ ɣöö ba jiek ɛ la mi̱ ro̱ŋ kɛ kui̱ thëmä min bi̱ raan te thi̱n mi̱ ŋotdɛ teekä.

Guäc kɛ pɛ̈th ɛ mi̱ di̱i̱t kɛ ɣöö bi̱ tuɔk kɛ kuën kɛnɛ riali̱kä kɛ kui̱i̱ teekä.

['Kuënɛ']

PubMed/Medline https://www.nlm.nih.gov/databases/download/pubmed_medline.html

RefinedWeb https://arxiv.org/abs/2306.01116

Liu SS, Zhu SQ: [Correlation between Alzheimer disease and cataract]. Zhonghua Yan Ke Za Zhi. 2017, 53 (4): 314-316.

Gauthier S: Practical guidelines for the antemortem diagnosis of senile dementia of the Alzheimer type. Prog Neuropsychopharmacol Biol Psychiatry. 1985, 9 (5-6): 491-5.

Rubin R: New Test to Help Diagnose Alzheimer Disease. JAMA. 2022, 327 (23): 2281.

[Blood Based Biomarker for Optimization of Early and Differential Diagnosis of Alzheimer's Dementia]. Fortschr Neurol Psychiatr. 2022, 90 (7-08): 326-335.

Kapp MB: Physicians' legal duties regarding the use of genetic tests to predict and diagnose Alzheimer disease. J Leg Med. 2000, 21 (4): 445-75.

Britschgi M, Wyss-Coray T: Blood protein signature for the early diagnosis of Alzheimer disease. Arch Neurol. 2009, 66 (2): 161-5.

Volicer L, Berman SA, Cipolloni PB, Mandell A: Persistent vegetative state in Alzheimer disease. Does it exist? Arch Neurol. 1997, 54 (11): 1382-4.

Imabayashi E, Saitoh Y, Tsukamoto T, Sakata M, Takano H: Combination of Astrogliosis and Phosphorylated Tau for the Preclinical Diagnosis of Alzheimer Disease Using 3-Dimensional Stereotactic Surface Projection Images With 18 F-THK5351. Clin Nucl Med. 2022, 47 (12): 1066-1068.

Martínez A, Lahiri DK, Giacobini E, Greig NH: Advances in Alzheimer therapy: understanding pharmacological approaches to the disease. Curr Alzheimer Res. 2009, 6 (2): 83-5.

['Lät kɛ kui̱i̱ jua̱thni̱']

['Ɛn wɛbthaay ɛmɛ ca la̱th lät kɛ kui̱ ŋi̱i̱cä kɛnɛ läri kä /cɛ lot ni ɣöö ba ji̱ moc kɛ luäk ki̱mä kiɛ lät ti̱ gööl.']

['Lät kɛ läri tin ca ŋun /ca kɛ bi̱ lät kɛ ɣöö ba jua̱th jek kiɛ ba kɛ ciɛŋ, kä nɛy tin görkɛ luäk ki̱mädiɛn kärɔ̱ ba kɛ thiec kä ki̱m mi̱ tekɛ luäk ki̱mä.']

['Guic ɛ gɔaa ɛn ɣöö ɛn neural net min jak luɔc kä thie̱cni̱, /cɛ thuɔ̱k ɛlɔ̱ŋ mi̱ ci̱ ben kä nämbäri̱ tin te thi̱n. cetkɛ pek nath tin ca jek kɛ juey mi̱ rɛlrɔ.']

['Ni ciaŋ go̱ri ruac kä ki̱mdu kiɛ ram in kɔ̱ŋ mi ŋäc luäk pua̱a̱ny kɛ kui̱ jua̱thdu. /Cu ruac ki̱mdu car kiɛ jääny kɛ go̱ri kɛ kui̱ kä mi ci kuɛn kä wɛbthaay ɛmɛ. Mi caari jɛ ɛn ɣöö deri tekɛ juey mi go̱o̱ri luäk, cɔl 911 kiɛ wër guäth in thia̱k kɛ ji kɛ pɛ̈th. /Thilɛ maar kam ki̱m kɛnɛ juey mi bi̱ tuɔɔk kɛ kui̱ kä wɛbthaay ɛmɛ kiɛ la̱tdɛ. /Ci̱ BioMedLib kiɛ la̱a̱tkɛ, kiɛ ram in gɔ̱a̱r kɛ kui̱ kä wɛbthaay ɛmɛ, bi̱ ruac lat, kiɛ bi̱ ruac lat, kɛ kui̱ läri tin ca ka̱m raar rɛydɛ kiɛ la̱tdɛ.']

['Lät kɛ: ŋuɔ̱t']

['Ɛn Digital Millennium Copyright Act 1998, 17 U.S.C. § 512 (ɛ DMCA) ɛ ŋuɔ̱t mi̱ ŋun ji̱ cuŋni̱ tin ŋääth kɛn ɣöö ci̱ ŋɔaani̱ tin te kä intɛrnɛt ŋuɔ̱tkiɛn to̱l kɛ kui̱ ŋuɔ̱tni̱ cuŋni̱ tin te kä U.S.']

['Mi ca ji̱ ŋäth kɛ thuɔ̱k ɛn ɣöö tëëkɛ mi̱ ca gɔ̱r kiɛ mi̱ ca ka̱m ji̱ rɛy wɛbthaayäda kiɛ lät tin kɔ̱ŋ tin ci̱ ŋuɔ̱t tin ca gɔ̱r ya̱r, ji̱n (kiɛ ram in lät kɛ kui̱du) deri̱ kɔ jäk kä warɛgak mi̱ bi̱ ji̱ thiec ɛn ɣöö ba min ca gɔ̱r kiɛ min ca gɔ̱r woc, kiɛ ba duɔ̱ɔ̱r la̱t kɛ ɣöö bi̱ ji̱ cop thi̱n.']

['Kɛn läri̱ ba kɛ jäk kɛ wargak ɛ la i̱thtäm (guic ni̱ gua̱th in ci̱ i̱thtäm in ca gɔ̱r "Kɔntak" kɛ kui̱ i̱thtäm in ci̱ jäk).']

['DMCA go̱o̱rɛ ɣöö bi̱ ji̱n warɛgakdu lat kɛ kui̱ kä tin ca lar i̱ ci̱ ŋuɔ̱t gɛr kɛ kui̱i̱ ŋuɔ̱tni̱ gɔ̱rä mat thi̱n kɛ läär ti̱ti̱: (1) latdɛ kɛ kui̱i̱ la̱t in ca gɛr kɛ kui̱i̱ ŋuɔ̱tni̱ gɔ̱rä min ca lar i̱ ca gɛr; (2) latdɛ kɛ kui̱i̱ kä tin ca lar i̱ ci̱ ŋuɔ̱t gɛr kɛnɛ läär ti̱ ro̱ŋ kɛ ɣöö bi̱ kɔn kɛ jek; (3) läri̱ kɛ kui̱i̱ kä min dëë ji̱ luäk kɛ jek, amäni̱ ci̱ötdu, nämbärɛ kä tin ci̱ ji̱ luäk kɛ jek, kɛnɛ emaildu; (4) latdu kɛ ɣöö ci̱ ji̱n ɛ ŋa̱c ɛn ɣöö min ca gɔ̱r kɛ kui̱i̱ kä tin ca lar /ci̱kɛ bi̱ lät kɛ luäkdɛ ɛ gua̱n ŋuɔ̱tni̱ gɔ̱rä, kiɛ ɛ la̱tdɛ, kiɛ kɛ luäk ŋuɔ̱tni̱; ']

['(5) mi ci ji gɔr piny kɛ kuic kä ɣöö bi ji ruac kɛ thuɔ̱k, ɛn ɣöö läri tin ca gɔr ɛ thuɔ̱k kä te ji kɛ lua̱ŋ kɛ ɣöö bi yiöw tin ca gɔr piny tin ca lar ɛ ji̱n ka̱m raar;']

['kɛnɛ (6) mi̱ ca gɔ̱r piny ɛ gua̱n ŋuɔ̱tni̱ kiɛ ram mi̱ tekɛ lua̱ŋ kɛ lät kɛ kui̱dɛ.']

['Mi /kenɛ läri tin ca lat nhial diaal mat thi̱n dɔ̱ŋ derɛ ku lɛ wɔ̱ jɔ̱ɔ̱r kɛ lätni̱ kɛ kɛ.']

['Röm kɛ jɛ']

['Thiecɛ kɔ kɛ email kɛ thiecni kiɛ cär.']

How is alzheimer diagnosed?

Alzheimer's disease is diagnosed through a combination of methods, including a thorough medical evaluation, cognitive and neuropsychological tests, brain imaging, and the process of elimination of other possible causes.

1. Medical evaluation: A doctor will perform a physical examination and take a detailed medical history to rule out other possible causes of memory loss or cognitive decline, such as thyroid problems, vitamin deficiencies, or brain tumors.

2. Cognitive and neuropsychological tests: These tests assess memory, language, problem-solving, and other cognitive functions to determine the extent of cognitive impairment and to differentiate between normal age-related memory loss and dementia.

3. Brain imaging: Magnetic resonance imaging (MRI) or computed tomography (CT) scans can help identify structural changes in the brain that may indicate Alzheimer's disease.

Positron emission tomography (PET) scans can also be used to measure the levels of certain proteins associated with Alzheimer's disease.

4. Blood tests: Recent research has shown that certain blood tests can help diagnose Alzheimer's disease by measuring the levels of specific proteins or biomarkers associated with the disease.

5. Process of elimination: Since there is no single definitive test for Alzheimer's disease, diagnosis often involves ruling out other possible causes of dementia-like symptoms.

It is important to note that a definitive diagnosis of Alzheimer's disease can only be made after death through an examination of brain tissue.

However, current diagnostic methods can provide a high level of certainty for a clinical diagnosis while the person is still alive.

Early diagnosis is important for starting treatment and planning for the future.

Disclaimer: medical

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Please note the neural net that generates answers to the questions, is specially inaccurate when it comes to numeric content. For example, the number of people diagnosed with a specific disease.

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