How is Lung cancer diagnosed?

['Liɛŋ wargak ɛmɛ']

Kä kancer puɔ̱nydɛ la ŋa̱ckɛ jɛ i̱di̱?

Kɛnthɛr puɔ̱nydɛ laa jɛ laa thɛmkɛ kɛ thëm ti̱ gööl, tin laa te thi̱n:

1.Thilɛ̈m kɛnɛ guäc pua̱a̱ny: Bi̱ ki̱th thiec kɛ kui̱ nyuuthni̱ tin tekɛ ji̱, wal tin laa täthkɛ wal, kɛnɛ tëë ci̱ ji̱ gɔaari̱du tekɛ juey thëm pua̱a̱ny.

Kɛn bä bikɛ ji guic kɛ ɣöö bi̱ kɛn ɛ nɛn ɛn ɣöö tëëkɛ nyuuthni̱ ti̱ ci̱ jɔɔc kä juey.

2. Imaging thɛmni̱: Thɛth X-rayni̱ kɛnɛ kɔmpi̱e̱e̱tɛr tomögi̱ra̱pi̱ (CT) i̱thkanni̱ laa kɛ laa la̱tkɛ kɛ ɣöö baa thurbiɛli̱ kɛnɛ tin te gekädiɛn ŋa̱c.

Thɛmni̱ ti̱ti̱ de luäk kɛ jiek ŋɔaani̱ tin /ci̱ rɔ̱ lot, ce̱tkɛ tuɔmni̱ kiɛ tin /ci̱ rɔ̱ lot, tin de nyoth ni̱ ta̱a̱ kanthɛr puɔ̱ɔ̱ny.

3. Sputum cytology: Tha̱a̱ŋ thuɔmdu (luɔm mi̱ ci̱ rɔ luäŋ raar rɛy puɔ̱ɔ̱nydu) ba jɛ guic kɛ mi̱thkɔ̱thkɔp kɛ ɣöö ba thëlli̱ kanthɛrä guic.

4. Bi̱öpthä: Bi̱ tha̱a̱ŋ pua̱a̱ny pua̱a̱ny woc kä ba guic kɛ maykrɔthkɔp kɛ ɣöö ba ŋa̱c mi̱ te thëlli̱ kanthɛr thi̱n.

Nɛmɛ derɛ la̱t kɛ duɔ̱ɔ̱p mi̱ cie bronchoscopy, needle biopsy, kiɛ surgical biopsy.

5.Bronkɔthkɔpi̱: Ɛ tuub mi̱ ciwciw, mi̱ ci̱ buay kɛ kɔmera mi̱ ca la̱th rɛy ŋɛ̈ɛ̈r kiɛ thok kɛnɛ piny rɛy ŋɛ̈ɛ̈r kɛ ɣöö ba jiɔm kɛnɛ puɔ̱nydɛ guic.

Ɛn ta̱a̱ la̱t ɛmɛ dëë jɛ la̱t bä kɛ ɣöö ba ŋɔak ti̱ ca thɛm kä bi̱öpthyi̱ (biopsy) kulɛ naŋ.

6. Kɛn thëm tin laa la̱tkɛ kɛ thëm mi̱ tɔt (FNA): Kɛn thëm tin tɔatni̱ laa kɛ laa la̱thkɛ rɛy puɔ̱ɔ̱ny ran kɛ ɣöö baa thɛl mi̱ tɔt kulɛ thɛm.

7. Thoracentesis: Ca pi̱w woc rɛy gua̱th in te kam puɔ̱ny kɛnɛ ji̱th pua̱a̱ny kɛ läth wäl, kä cua pi̱w ɛmɔ thɛm kɛ kui̱ thëlli̱ kanthɛrä.

8. Kɛn thɛmni̱ riɛm: Niɛ gua̱a̱ mɔ thɛmni̱ riɛm kärɔ̱ /cɛ kɛ luäŋ kɛ ɣöö ba kanthɛr puɔ̱ɔ̱ny jek, kɛn luäk kɛ ɣöö ba ta̱a̱ puɔ̱ny ran jek kä ba tin /ci̱ rɔ̱ lot tin nyoth ɣöö tekɛ kanthɛr ŋa̱c.

9. Kɔnthɛrɛn, MRI, PET thëm, kɛnɛ thëm kɔ̱kiɛn: Kɛn thëm ti̱ti̱ dëë kɛ la̱t kɛ ɣöö ba ŋa̱c mi̱ ci̱ kanthɛr däk kä tha̱a̱ŋ pua̱a̱nyni̱ kɔ̱kiɛn.

Mi ca jek ɛn ɣöö te kɛ kancer puɔ̱ny, thëm kɔ̱kiɛn de kɛ la̱t kɛ ɣöö ba pek in te kancer thi̱n ŋa̱c, min luäk kɛ ɣöö ba ji̱ek kɛ kui̱ kä min ba lät kɛ jɛ.

Thëm ti̱ti̱ de kɛ mat ni̱ thëm mi̱ di̱i̱t mi̱ la̱tkɛ kɛ cäätdɛ, ce̱tkɛ CT thëm ŋithä, thëm pua̱a̱ny, kiɛ thëm mi̱ cɔali̱ positron emission tomography (PET) thëm.

['Kuënɛ']

PubMed/Medline https://www.nlm.nih.gov/databases/download/pubmed_medline.html

RefinedWeb https://arxiv.org/abs/2306.01116

Zhou P, Lu F, Wang J, Wang K, Liu B, Li N, Tang B: A portable point-of-care testing system to diagnose lung cancer through the detection of exosomal miRNA in urine and saliva. Chem Commun (Camb). 2020, 56 (63): 8968-8971.

Ni J, Guo Z, Zhang L: [The diagnostic significance of single or combination lung cancer-related serum biomarkers in high risk lung cancer patients]. Zhonghua Nei Ke Za Zhi. 2016, 55 (1): 25-30.

Nishiyama N, Nakatani S, Iwasa R, Taguchi S, Inoue K, Kinoshita H: [Differential diagnosis between peripheral lung cancer invading the chest wall and chest-wall tumors]. Kyobu Geka. 1997, 50 (10): 893-7.

Kang C, Wang D, Zhang X, Wang L, Wang F, Chen J: Construction and Validation of a Lung Cancer Diagnostic Model Based on 6-Gene Methylation Frequency in Blood, Clinical Features, and Serum Tumor Markers. Comput Math Methods Med. 2021, 2021 (): 9987067.

Heydari F, Rafsanjani MK: A Review on Lung Cancer Diagnosis Using Data Mining Algorithms. Curr Med Imaging. 2021, 17 (1): 16-26.

Li L, Feng T, Zhang W, Gao S, Wang R, Lv W, Zhu T, Yu H, Qian B: MicroRNA Biomarker hsa-miR-195-5p for Detecting the Risk of Lung Cancer. Int J Genomics. 2020, 2020 (): 7415909.

Li B, Yuan Q, Zou YT, Su T, Lin Q, Zhang YQ, Shi WQ, Liang RB, Ge QM, Li QY, Shao Y: CA-125, CA-153, and CYFRA21-1 as clinical indicators in male lung cancer with ocular metastasis. J Cancer. 2020, 11 (10): 2730-2736.

Magee ND, Villaumie JS, Marple ET, Ennis M, Elborn JS, McGarvey JJ: Ex vivo diagnosis of lung cancer using a Raman miniprobe. J Phys Chem B. 2009, 113 (23): 8137-41.

['Lät kɛ kui̱i̱ jua̱thni̱']

['Ɛn wɛbthaay ɛmɛ ca la̱th lät kɛ kui̱ ŋi̱i̱cä kɛnɛ läri kä /cɛ lot ni ɣöö ba ji̱ moc kɛ luäk ki̱mä kiɛ lät ti̱ gööl.']

['Lät kɛ läri tin ca ŋun /ca kɛ bi̱ lät kɛ ɣöö ba jua̱th jek kiɛ ba kɛ ciɛŋ, kä nɛy tin görkɛ luäk ki̱mädiɛn kärɔ̱ ba kɛ thiec kä ki̱m mi̱ tekɛ luäk ki̱mä.']

['Guic ɛ gɔaa ɛn ɣöö ɛn neural net min jak luɔc kä thie̱cni̱, /cɛ thuɔ̱k ɛlɔ̱ŋ mi̱ ci̱ ben kä nämbäri̱ tin te thi̱n. cetkɛ pek nath tin ca jek kɛ juey mi̱ rɛlrɔ.']

['Ni ciaŋ go̱ri ruac kä ki̱mdu kiɛ ram in kɔ̱ŋ mi ŋäc luäk pua̱a̱ny kɛ kui̱ jua̱thdu. /Cu ruac ki̱mdu car kiɛ jääny kɛ go̱ri kɛ kui̱ kä mi ci kuɛn kä wɛbthaay ɛmɛ. Mi caari jɛ ɛn ɣöö deri tekɛ juey mi go̱o̱ri luäk, cɔl 911 kiɛ wër guäth in thia̱k kɛ ji kɛ pɛ̈th. /Thilɛ maar kam ki̱m kɛnɛ juey mi bi̱ tuɔɔk kɛ kui̱ kä wɛbthaay ɛmɛ kiɛ la̱tdɛ. /Ci̱ BioMedLib kiɛ la̱a̱tkɛ, kiɛ ram in gɔ̱a̱r kɛ kui̱ kä wɛbthaay ɛmɛ, bi̱ ruac lat, kiɛ bi̱ ruac lat, kɛ kui̱ läri tin ca ka̱m raar rɛydɛ kiɛ la̱tdɛ.']

['Lät kɛ: ŋuɔ̱t']

['Ɛn Digital Millennium Copyright Act 1998, 17 U.S.C. § 512 (ɛ DMCA) ɛ ŋuɔ̱t mi̱ ŋun ji̱ cuŋni̱ tin ŋääth kɛn ɣöö ci̱ ŋɔaani̱ tin te kä intɛrnɛt ŋuɔ̱tkiɛn to̱l kɛ kui̱ ŋuɔ̱tni̱ cuŋni̱ tin te kä U.S.']

['Mi ca ji̱ ŋäth kɛ thuɔ̱k ɛn ɣöö tëëkɛ mi̱ ca gɔ̱r kiɛ mi̱ ca ka̱m ji̱ rɛy wɛbthaayäda kiɛ lät tin kɔ̱ŋ tin ci̱ ŋuɔ̱t tin ca gɔ̱r ya̱r, ji̱n (kiɛ ram in lät kɛ kui̱du) deri̱ kɔ jäk kä warɛgak mi̱ bi̱ ji̱ thiec ɛn ɣöö ba min ca gɔ̱r kiɛ min ca gɔ̱r woc, kiɛ ba duɔ̱ɔ̱r la̱t kɛ ɣöö bi̱ ji̱ cop thi̱n.']

['Kɛn läri̱ ba kɛ jäk kɛ wargak ɛ la i̱thtäm (guic ni̱ gua̱th in ci̱ i̱thtäm in ca gɔ̱r "Kɔntak" kɛ kui̱ i̱thtäm in ci̱ jäk).']

['DMCA go̱o̱rɛ ɣöö bi̱ ji̱n warɛgakdu lat kɛ kui̱ kä tin ca lar i̱ ci̱ ŋuɔ̱t gɛr kɛ kui̱i̱ ŋuɔ̱tni̱ gɔ̱rä mat thi̱n kɛ läär ti̱ti̱: (1) latdɛ kɛ kui̱i̱ la̱t in ca gɛr kɛ kui̱i̱ ŋuɔ̱tni̱ gɔ̱rä min ca lar i̱ ca gɛr; (2) latdɛ kɛ kui̱i̱ kä tin ca lar i̱ ci̱ ŋuɔ̱t gɛr kɛnɛ läär ti̱ ro̱ŋ kɛ ɣöö bi̱ kɔn kɛ jek; (3) läri̱ kɛ kui̱i̱ kä min dëë ji̱ luäk kɛ jek, amäni̱ ci̱ötdu, nämbärɛ kä tin ci̱ ji̱ luäk kɛ jek, kɛnɛ emaildu; (4) latdu kɛ ɣöö ci̱ ji̱n ɛ ŋa̱c ɛn ɣöö min ca gɔ̱r kɛ kui̱i̱ kä tin ca lar /ci̱kɛ bi̱ lät kɛ luäkdɛ ɛ gua̱n ŋuɔ̱tni̱ gɔ̱rä, kiɛ ɛ la̱tdɛ, kiɛ kɛ luäk ŋuɔ̱tni̱; ']

['(5) mi ci ji gɔr piny kɛ kuic kä ɣöö bi ji ruac kɛ thuɔ̱k, ɛn ɣöö läri tin ca gɔr ɛ thuɔ̱k kä te ji kɛ lua̱ŋ kɛ ɣöö bi yiöw tin ca gɔr piny tin ca lar ɛ ji̱n ka̱m raar;']

['kɛnɛ (6) mi̱ ca gɔ̱r piny ɛ gua̱n ŋuɔ̱tni̱ kiɛ ram mi̱ tekɛ lua̱ŋ kɛ lät kɛ kui̱dɛ.']

['Mi /kenɛ läri tin ca lat nhial diaal mat thi̱n dɔ̱ŋ derɛ ku lɛ wɔ̱ jɔ̱ɔ̱r kɛ lätni̱ kɛ kɛ.']

['Röm kɛ jɛ']

['Thiecɛ kɔ kɛ email kɛ thiecni kiɛ cär.']

How is lung cancer diagnosed?

Lung cancer is diagnosed through a combination of tests and procedures, which may include:

1. Medical history and physical examination: The doctor will ask about your symptoms, smoking history, and family history of lung cancer.

They will also perform a physical examination to check for any signs of the disease.

2. Imaging tests: Chest X-rays and computed tomography (CT) scans are commonly used to create detailed images of the lungs and surrounding structures.

These tests can help detect abnormalities, such as tumors or nodules, that may indicate the presence of lung cancer.

3. Sputum cytology: A sample of your sputum (mucus coughed up from the lungs) is examined under a microscope to look for cancer cells.

4. Biopsy: A sample of lung tissue is removed and examined under a microscope to determine if cancer cells are present.

This can be done through a bronchoscopy, needle biopsy, or surgical biopsy.

5. Bronchoscopy: A thin, lighted tube with a camera is inserted through the nose or mouth and down the throat to examine the airways and lungs.

This procedure can also be used to collect tissue samples for biopsy.

6. Fine-needle aspiration (FNA): A thin needle is inserted into the lung nodule or mass to collect a sample of cells for examination.

7. Thoracentesis: Fluid is removed from the space between the lungs and chest wall using a needle, and the fluid is then examined for cancer cells.

8. Blood tests: While blood tests alone cannot diagnose lung cancer, they can help determine the overall health of the patient and identify any abnormalities that may indicate the presence of cancer.

9. Bone scan, mri, pet scan, and other tests: These tests may be used to determine if the cancer has spread to other parts of the body.

Once lung cancer is diagnosed, additional tests may be performed to determine the stage of the cancer, which helps guide treatment decisions.

These tests may include more imaging tests, such as a CT scan of the brain, bone scan, or positron emission tomography (PET) scan.

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