L'urticària, comunament coneguda coma rusca, es una malautiá de la pèl caracterizada per l'apareisson de roncas rojas, grassas e picantas sus la pèl.
La fisiopatologia de l'urticària implica la liberacion d'istamina e d'autres mediators inflammatòris dels mastòcits, que son de cellulas immunitàrias de la pèl e d'autres teissuts.
Dins l'urticària aguda, la liberacion d'istamina e d'autres mediators es provocada per una reaccion allergica a un alergèn especific, coma los aliments, medicaments, o la fissada d'insècte.
Aquò provòca la desgranulacion dels mastòcits, liberant d'istamina e d'autres mediators que fan que los vaissèls sanguins vengan permeables, menant a la formacion de las ròdas.
Dins l'urticària cronica, la causa es sovent desconeguda, mas se pensa qu'es ligada a un mecanisme autoimun.
Dins aqueste cas, l'organisme produch d'autoanticòrs que ciblan lo receptor IgE d'afinitat nauta (FcεRI) suls mastòcits, menant a lor activacion e a la liberacion d'istamina e d'autres mediators.
Dins l'urticària aguda e cronica, la liberacion d'istamina e d'autres mediators mena als simptòmas caracteristics de picor, rojor e tumefaccion.
Lo tractament implica tipicament l'usatge d'antiistaminas per blocar los efièch de l'istamina e reduire los simptòmas.
Dins los cases grèus, d'autres medicaments coma los corticosteroïdes o omalizumab pòdon èsser utilizats per contrarotlar la malautiá.
Wahlgren CF: Pathophysiology of itching in urticaria and atopic dermatitis. Allergy. 1992, 47 (2 Pt 1): 65-75.
Raap U, Liekenbröcker T, Wieczorek D, Kapp A, Wedi B: [New therapeutic strategies for the different subtypes of urticaria]. Hautarzt. 2004, 55 (4): 361-6.
[Recommendations for the diagnosis and treatment of urticaria in children]. Arch Argent Pediatr. 2021, 119 (2): S54-S66.
Brzoza Z, Grzeszczak W, Rogala B, Trautsolt W, Moczulski D: Possible contribution of chemokine receptor CCR2 and CCR5 polymorphisms in the pathogenesis of chronic spontaneous autoreactive urticaria. Allergol Immunopathol (Madr). , 42 (4): 302-6.
Sweeney TM, Dexter WW: Cholinergic urticaria in a jogger: ruling out exercise-induced anaphylaxis. Phys Sportsmed. 2003, 31 (6): 32-6.
['Disclaimer: medecina']
['Aqueste site internet es porgit sonque per tòca educativa e informativa e constituís pas un conselh medical o de servici professional.']
['Las informacions donadas se devon pas utilizar per diagnosticar o tractar un problèma de santat o malautiá, e los que cercan un conselh medical personal se devon consultar amb un mètge autorizat.']
["Notatz que lo malhum neuronal que genèra las responsas a las questions, es subretot inexacte al subjècte del contengut numeric. Per exemple, lo nombre de personas diagnosticadas d'una malautiá especifica."]
["Sempre demandar lo conselh de vòstre mètge o d'un autre provesidor de santat qualificat al subjècte d'una condicion medicala. Jamai non pas considerar los conselhs professionals o lo retard per los cercar a causa de quicòm qu'avètz legit sus aqueste site."]
["Disclaimer: Drech d'autor"]
["Lo Digital Millennium Copyright Act de 1998, 17 U.S.C. § 512 (lo DMCA) prevei de recors pels proprietaris dels dreches d'autor que creson que lo material qu'apareis sus Internet infringe lors dreches segon la lei dels dreches d'autor dels EUA. "]
["Se cresètz de bona fe que quin contengut que siá o quin material que siá mes a dispausicion en relacion amb nòstre sit web o nòstres servicis infringe vòstre drech d'autor, vos (o vòstre agent) podètz nos mandar un avertiment demandant que lo contengut o material siá levat, o que l'accès li siá blocat."]
['Los anoncis se devon mandar per escrich per corrièr electronic (vejatz la seccion "Contacte" per l\'adreça).']
["La DMCA exigís que vòstre avís sus la violacion de copyright inclusís las informacions seguentas: (1) descripcion de l'òbra protegida qu'es l'objècte de la violacion; (2) descripcion del contengut sus que se pretend la violacion e informacion sufisenta per nos permetre de localizar lo contengut; (3) vòstras informacions de contacte, coma vòstra adreça, numèro de telefòn e adreça e-mail; (4) una declaracion que cresètz de bona fe que lo contengut de la mena que se reclama es pas autorizat pel proprietari del copyright, o son agent, o per l'aplicacion de quina lei que siá; "]
["5) una declaracion signada per vos, jos pena de perjure, que las informacions contengudas dins la notificacion son precisas e qu'avètz l'autoritat per far valer los dreches d'autor que se pretendon èsser violats;"]
["e (6) una signatura fisica o electronica del proprietari del copyright o d'una persona autorizada a agir al nom del proprietari. "]
["Lo manca d'inclure totas las informacions çai sus pòt provocar un retard dins lo tractament de vòstra reclamacion."]
['Contacte']
['Mandatz-nos un email amb vòstras questions / suggestions.']
What is pathophysiology of urticaria?
Urticaria, commonly known as hives, is a skin condition characterized by the appearance of itchy, raised, red welts (wheals) on the skin.
The pathophysiology of urticaria involves the release of histamine and other inflammatory mediators from mast cells, which are immune cells found in the skin and other tissues.
In acute urticaria, the release of histamine and other mediators is triggered by an allergic reaction to a specific allergen, such as food, medication, or insect sting.
This causes the mast cells to degranulate, releasing histamine and other mediators that cause blood vessels to become leaky, leading to the formation of wheals.
In chronic urticaria, the cause is often unknown, but it is thought to be related to an autoimmune mechanism.
In this case, the body produces autoantibodies that target the high-affinity IgE receptor (FcεRI) on mast cells, leading to their activation and the release of histamine and other mediators.
In both acute and chronic urticaria, the release of histamine and other mediators leads to the characteristic symptoms of itching, redness, and swelling.
Treatment typically involves the use of antihistamines to block the effects of histamine and reduce symptoms.
In severe cases, other medications such as corticosteroids or omalizumab may be used to control the condition.
Disclaimer: medical
This web site is provided for educational and informational purposes only and does not constitute providing medical advice or professional services.
The information provided should not be used for diagnosing or treating a health problem or disease, and those seeking personal medical advice should consult with a licensed physician.
Please note the neural net that generates answers to the questions, is specially inaccurate when it comes to numeric content. For example, the number of people diagnosed with a specific disease.
Always seek the advice of your doctor or other qualified health provider regarding a medical condition. Never disregard professional medical advice or delay in seeking it because of something you have read on this website. If you think you may have a medical emergency, call 911 or go to the nearest emergency room immediately. No physician-patient relationship is created by this web site or its use. Neither BioMedLib nor its employees, nor any contributor to this web site, makes any representations, express or implied, with respect to the information provided herein or to its use.
Disclaimer: copyright
The Digital Millennium Copyright Act of 1998, 17 U.S.C. § 512 (the “DMCA”) provides recourse for copyright owners who believe that material appearing on the Internet infringes their rights under U.S. copyright law. If you believe in good faith that any content or material made available in connection with our website or services infringes your copyright, you (or your agent) may send us a notice requesting that the content or material be removed, or access to it blocked. Notices must be sent in writing by email (see 'Contact' section for email address) . The DMCA requires that your notice of alleged copyright infringement include the following information: (1) description of the copyrighted work that is the subject of claimed infringement; (2) description of the alleged infringing content and information sufficient to permit us to locate the content; (3) contact information for you, including your address, telephone number and email address; (4) a statement by you that you have a good faith belief that the content in the manner complained of is not authorized by the copyright owner, or its agent, or by the operation of any law; (5) a statement by you, signed under penalty of perjury, that the information in the notification is accurate and that you have the authority to enforce the copyrights that are claimed to be infringed; and (6) a physical or electronic signature of the copyright owner or a person authorized to act on the copyright owner’s behalf. Failure to include all of the above information may result in the delay of the processing of your complaint.
["A l'entorn de"]
["BioMedLib utiliza d'ordinators automatics (algoritmes d'aprendissatge automatic) per generar de parelhs de questions e responsas."]
['Començam amb 35 milions de publicacions biomedicalas de PubMed/Medline. Tanben, paginas web de RefinedWeb.']
