What is pathophysiology of Diabetes?

['Umviriza uru rupapuro']

Ingwara y'igisukari imeze gute?

Inyigisho y'indwara y'igisukari yerekeye ingene umubiri ukora mu gihe umuntu arwaye indwara y'igisukari.

Indwara y'igisukari yo mu bwoko bwa 2 ni indwara ifatira mu bihimba vy'umubiri, ikaba iterwa n'ukugira isukari nyinshi mu maraso biturutse ku kuba umubiri udasohora neza inkabuzo bita insuline canke ugasanga iyo inkabuzo ntiyikora neza.

Ingorane z'indwara y'igisukari ziterwa n'utugingo ngengakamere, ibidukikije be n'uburyo umuntu abayeho.

Mu ndwara y'igisukari yo mu bwoko bwa 1, indwara y'umubiri ituma uduhimba beta dutanga ya misemburo bita pancreas dutakaza ubushobozi bwo guhingura ya misemburo bita insuline.

Ivyo bituma umuntu adashobora gucungera urugero rw'isukari iri mu maraso, bigatuma arwara indwara yitwa hyperglycémie (isukari nyinshi mu maraso).

Mu gihe umuntu arwaye indwara y'igisukari yo mu bwoko bwa 2, indwara y'igisukari irunyuka cane, bigatuma umuntu adashobora guhingura neza ya miti irwanya indwara y'igisukari.

Iyo umuntu yanse guterwa ya nkabuzo bita insuline, umubiri wiwe ntuba ugishobora gukoresha neza ya nkabuzo kugira ngo uronke inguvu.

Ivyo bituma nya kabuto gatanga indemamubiri nyinshi kugira ngo gahangane n'iyo ndwara, ariko uko igihe kirengana, karashobora kudashobora gukora izo nkenerwa, bigatuma gatanga izo indemamubiri nkeyi.

Iyo ndwara iterwa n'amahinduka aba mu mubiri w'umugore igihe yibungenze, ivyo bigatuma umubiri wiwe utakira neza ya miti bita insuline.

Iyo mbanyi irakora uduhimba twitwa hormones dushobora kubuza insuline gukora, bigatuma urugero rw'isukari mu maraso rwiyongera.

Ingorane z'indwara y'igisukari zirimwo n'izindi, nk'ugukomereka kw'imitsi itwara amaraso, kw'udutsi nsozabwenge be n'ibihimba vy'umubiri, ivyo na vyo bikaba bishobora gutuma umuntu arwara indwara zikomeye nk'umutima, indwara yo mu bwonko, indwara y'amafyigo be n'ukubura amaso.

Gutahura ukuntu indwara y'igisukari imeze ni ngirakamaro cane kugira ngo bashobore kuyirwanya neza.

['Ibitabu vyo muri Bibiliya']

PubMed/Medline https://www.nlm.nih.gov/databases/download/pubmed_medline.html

RefinedWeb https://arxiv.org/abs/2306.01116

Biochemistry and pathophysiology of diabetes. Proceedings of conference on pathophysiology and treatment of diabetes mellitus. 1990. Mol Cell Biochem. 1992, 109 (2): 97-204.

Surampudi PN, John-Kalarickal J, Fonseca VA: Emerging concepts in the pathophysiology of type 2 diabetes mellitus. Mt Sinai J Med. 2009, 76 (3): 216-26.

Johnson D: Selected pathophysiology of diabetes. Semin Perioper Nurs. 1998, 7 (3): 164-78.

Hirsch IB: The changing faces of diabetes. Prim Care. 2003, 30 (3): 499-510.

Guthrie RA, Guthrie DW: Pathophysiology of diabetes mellitus. Crit Care Nurs Q. , 27 (2): 113-25.

Palicka V: Pathophysiology of Diabetes Mellitus. EJIFCC. 2002, 13 (5): 140-144.

Felig P: Pathophysiology of diabetes mellitus. Med Clin North Am. 1971, 55 (4): 821-34.

['Urupapuro rwemeza ko ata ruhusha:']

["Uru rubuga rw'ivy'ubuvuzi ruratangwa ku bw'inyigisho no ku bw'ukumenyesha amakuru gusa, ntirutanga impanuro mu vy'ubuvuzi canke ngo rube urwego rw'abahinga mu vy'ubuvuzi."]

["Amakuru atangwa n'ivyo binyamakuru ntabereye gukoreshwa mu gusuzuma canke mu kuvura ingorane y'amagara canke indwara kanaka, kandi abarondera impanuro zijanye n'ivy'ubuvuzi bakwiye kwitura umuganga abifitiye uruhusha."]

["Urabona ko ubuhinga bwa none butanga inyishu z'ibibazo usanga butarimwo ukuri na canecane igihe ari ibitigiri, nk'akarorero igitigiri c'abantu barwaye indwara kanaka."]

["Niwame usaba impanuro umuganga wawe canke uwundi muntu abifitiye uburenganzira mu bijanye n'amagara yawe. Ntiwigere wirengagiza impanuro z'umuganga canke ngo ureke kuzirondera kubera ivyo wasomye kuri uyu muhora. Nimba wibaza ko hari ikintu cihutirwa mu vy'amagara, nuce uhamagara 911 canke uje aho bavurira indembe hagufi."]

["Igabishwa: uburenganzira bw'abafise ivyo banditse"]

["Itegeko ryo mu 1998 ryerekeye uburenganzira umuntu afise mu vyo akoresha mu guhanahana amakuru (Digital Millennium Copyright Act of 1998, 17 U.S.C. § 512 (the DMCA) ritanga uburenganzira ku bantu bafise uburenganzira bwo guhanahana amakuru babona ko ibintu vyerekanwa kuri Internet bihonyanga uburenganzira bwabo hisunzwe amategeko ya Leta Zunze Ubumwe za Amerika ajanye n'uburenganzira umuntu afise. "]

['Mu gihe wibaza ko hari ibintu canke ibikoresho vyabonetse ku rubuga rwacu canke ku mbuga zacu bibangamiye uburenganzira bwawe, wewe (canke uwukugenzura) urashobora kuturungikira ubutumwa busaba ko ivyo bintu canke ivyo bikoresho bikurwaho canke ko bitagisubira kuboneka. ']

['Amatangazo ategerezwa kurungikwa mu nyandiko hakoreshejwe ubutumwa bwa "email" (raba ahavuga ngo "Kwitaba" kugira ngo umenye aderese ya "email").']

["Itegeko rya DMCA risaba ko umenyesha ko hari uwugomba guhonyanga uburenganzira bwawe mu gutanga amakuru akurikira: (1) idondorwa ry'igikorwa gikingiwe n'amategeko kiriko kiragirizwa guhonyanga uburenganzira bwawe; (2) idondorwa ry'ibiri mu vyo bavuga ko bihonyanga uburenganzira bwawe be n'amakuru ahagije atuma dushobora kumenya aho biri; (3) amakuru y'ukuntu twokwifatanya nawe, harimwo aderese yawe, inomero za telefone n'ikete ryawe ryo kurungikiranira ubutumwa kuri internet; (4) ivyemeza ko wemera udakeka ko ivyo bintu biri mu buryo uriko uridodombera bitahawe uburenganzira n'uwabitunganije, canke uwubiserukira, canke n'itegeko iryo ari ryo ryose; "]

["(5) urwandiko rwanditswe n'uwatanze iyo notifica-tion, rwemeza ko amakuru ari muri iyo notifica-tion ari ay'ukuri kandi ko afise ububasha bwo gukurikirana ivy'uwo muntu avuga ko yahonyanze uburenganzira bwiwe; "]

["n' (6) umukono w'umuntu canke w'ubuhinga bwa elegitoronike w'uwuri n'ico kintu canke w'umuntu yahawe uburenganzira bwo gukora ku bw'uwo muntu. "]

['Kudashiramwo amakuru yose ari aho haruguru vyoshobora gutuma ivyo kwitwarira umuntu bicererwa.']

['Uwushobora kugufasha']

['Turakwinginze uturungikire ubutumwa kuri email ufise ikibazo / iciyumviro.']

What is pathophysiology of diabetes?

Pathophysiology of diabetes refers to the study of the disordered physiological processes that lead to the development of diabetes mellitus.

Diabetes mellitus is a group of metabolic diseases characterized by high blood sugar (glucose) levels that result from defects in insulin secretion, insulin action, or both.

The pathophysiology of diabetes involves the complex interplay of genetic, environmental, and lifestyle factors that contribute to the development of the disease.

In type 1 diabetes, the pathophysiology involves an autoimmune destruction of the insulin-producing beta cells in the pancreas, leading to a deficiency in insulin production.

This results in an inability to regulate blood glucose levels, leading to hyperglycemia (high blood sugar).

In type 2 diabetes, the pathophysiology is more complex and involves both insulin resistance and impaired insulin secretion.

Insulin resistance occurs when the body's cells do not respond properly to insulin, leading to an inability to effectively use glucose for energy.

This causes the pancreas to produce more insulin to try to overcome the resistance, but over time, the pancreas may not be able to keep up with the demand, leading to a decrease in insulin production.

Gestational diabetes, which occurs during pregnancy, is caused by hormonal changes that lead to insulin resistance.

The placenta produces hormones that can block the action of insulin, leading to an increase in blood glucose levels.

The pathophysiology of diabetes also involves the development of complications, such as damage to blood vessels, nerves, and organs, which can lead to serious health problems like heart disease, stroke, kidney disease, and vision loss.

Understanding the pathophysiology of diabetes is crucial for developing effective treatments and prevention strategies for this chronic disease.

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