How is Alzheimer diagnosed?

A yeke hinga kobela ti Alzheimer tongana nyen?

A yeke gi na lege ti akode nde nde ti hinga na kobela ti Alzheimer, so na popo ni a yeke wara mbeni nzoni gingo nda ti ye ti wanganga, gingo nda ti ye na ndo ngangu ti gbungo li ti zo nga na ti mongoli ti zo, gingo nda ti ye na ndo mongoli ti zo na lege ti afoto, nga na gingo ti zi ambeni ye nde so alingbi ti ga na kobela ni.

1. Gingo nda ti ye ti wanganga: Mbeni wanganga ayeke bâ seni ti zo ni nga lo yeke gi nda ti aye kue so asi na lo kozoni si lo bâ wala ambeni ye nde ayeke dä so asara si lo girisa aye wala lo hinga ye nzoni pëpe.

2. A-examen so abâ lege ti hingango ndo ti zo nga na ti mongoli ti zo: A-examen so ayeke bâ ngangu ti zo ti dabe na aye, ti sala tënë, ti leke akpale, nga na ambeni ye nde so zo ni ayeke sala ti hinga na ndo ti aye.

3. Gingo afoto ti mongoli: Gingo afoto ti mongoli na lege ti mbeni masini so ayeke sala kua na ngangu ti lo ti gboto aye na yâ ti tele ti zo (IRM) wala na lege ti mbeni masini so ayeke mû asango na ndo aye so ayeke tambela na yâ mongoli (CT) alingbi ti mû maboko ti hinga agbiango ye so ayeke si na yâ mongoli ti zo, so alingbi ti fa na gigi kobela ti Alzheimer.

A lingbi nga ti sala kusala na scanner so a hiri ni tomographie par émission de positons (PET) ti hinga wungo ti ambeni protéine so ayeke na gunda ti kobela ti Alzheimer.

4. A-analyse ti mênë: Ade ti ninga pëpe, gingo nda ti ye afa so ambeni gingo nda ti mênë alingbi ti mû maboko ti hinga kobela ti Alzheimer na lege ti dikongo wungo ti ambeni ye so ayeke fa na ndo seni ti zo.

5. Kode ti ziango ni: Teti so mbeni kode oko ti hinga na kobela ti Alzheimer ayeke dä pëpe, fani mingi a hunda ti gi ti hinga ambeni ye nde so alingbi ti ga na akobela so akpa kobela ti li.

A yeke kota ye ti hinga so a lingbi ti hinga biani kobela ti Alzheimer gi na peko ti kuâ ti zo ni, na lege ti gingo yâ ti mongoli ti lo.

Ye oko, akode ti gingo nda ti kobela so azo ayeke sala laso alingbi ti mû lege na ala ti hinga biani so kobela ni ayeke si na ngoi so zo ni angbâ na fini.

Ti hinga kobela ti zo hio ayeke kota ye mingi ti to nda ti kaïngo kobela ni nga ti leke ye teti kekereke.

['Atënë so a bâ na ndo ni']

PubMed/Medline https://www.nlm.nih.gov/databases/download/pubmed_medline.html

RefinedWeb https://arxiv.org/abs/2306.01116

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[Blood Based Biomarker for Optimization of Early and Differential Diagnosis of Alzheimer's Dementia]. Fortschr Neurol Psychiatr. 2022, 90 (7-08): 326-335.

Kapp MB: Physicians' legal duties regarding the use of genetic tests to predict and diagnose Alzheimer disease. J Leg Med. 2000, 21 (4): 445-75.

Britschgi M, Wyss-Coray T: Blood protein signature for the early diagnosis of Alzheimer disease. Arch Neurol. 2009, 66 (2): 161-5.

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Imabayashi E, Saitoh Y, Tsukamoto T, Sakata M, Takano H: Combination of Astrogliosis and Phosphorylated Tau for the Preclinical Diagnosis of Alzheimer Disease Using 3-Dimensional Stereotactic Surface Projection Images With 18 F-THK5351. Clin Nucl Med. 2022, 47 (12): 1066-1068.

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['Tënë ti ziango kamene na lê: tënë ti seni']

['A zia site so gi ti fa na ye na azo na ti mû wango na ala.']

['A lingbi a sala kusala pëpe na asango so a mû ti hinga wala ti kaï na mbeni kpale ti seni wala kobela, na a lingbi ala so aye ti wara wango ti kaïngo kobela teti ala mveni ahunda mbeni wanganga so ayeke na mbeti ti hinga ye na ndo ni.']

['Bâ so tongana a hunda na zo ti fa wungo ti azo so ayeke na mbeni kobela, a yeke ngangu ti tene lo fa tâ wungo ti azo ni.']

['Gi lakue wango ti wanganga ti mo wala mbeni wanganga so ahinga kua ti lo nzoni na ndo ti kobela ti mo. Zia lâ oko pëpe ti ke wango ti wanganga wala ti ku ti wara ni ndali ti mbeni ye so mo diko na ndo ti site so. Tongana mo bâ so mo yeke na yâ ti mbeni kpale ti seni, iri 911 wala gue hio na hôpital so ayeke nduru na mo.']

['Kengo tene: droit ti lo ti sala tene']

['Ndia ti Amerika na ndo droit ti sigingo na ambeti (Digital Millennium Copyright Act) ti ngu 1998, 17 U.S.C. § 512 (so a hiri ni DMCA) amû lege na azo so ayeke na droit ti sigingo na ambeti ti bâ wala ambeti so asigigi na ndo ti Internet ni adoro droit ti ala so ndia ti Amerika amû na ndo droit ti sigingo na ambeti amû lege na ala ti sala ni. ']

['Tongana mo pensé so mbeni ye so ayeke na ndo ti site ti e wala na yâ ti ambeni ye so e yeke sara andu droit ti mo ti batango ambeti ti e, mo (wala zo so mo sara kua na iri ti lo) alingbi ti tokua na e mbeni mbeti ti hunda ti tene a zi ni wala a kanga lege na mo ti wara ni.']

['A lingbi a tokua ambeti ni na lege ti mbeni lettre so a sû na ndo ti ordinateur wala na lege ti mbeni téléphone (bâ mbage "A-adresse ti téléphone").']

['Ndia ti DMCA ahunda ti tene na yâ ti mbeti ti mo so a tene mbeni zo asara mbeni ye so ake ndia ti droit ti batango ambeti, mo zia atënë so ge: (1) fango peko ti kua so ndia ti batango ambeti ni ake ni; (2) fango peko ti aye so a tene a sara ye ti ke ndia ti batango ambeti ni nga na atënë so alingbi ti mû lege na e ti wara aye ni so; (3) asango ti mo ti wara mo, so andu adresse ti mo, numéro ti téléphone ti mo nga na adresse ti e-mail ti mo; (4) mbeni tënë so mo tene na bê ti mo kue so tënë ti aye ni so mo dema tere dä so ayeke pëpe tënë ti zo so ayeke na droit ti batango ambeti ni, wala zo so ayeke sara kua na iri ti lo, wala ndia ti kodoro ti mo.']

['(5) Mo sû maboko ti mo na gbe ti ngbanga ti mvene na mo tene so atënë so ayeke na yâ ti mbeti ni ayeke tâ tënë nga so mo yeke na ngangu ti sara si a bata droit ti mo ti sigingo na ambeti so a tene a doro ni.']

['Nga (6) mbeni maboko ti zo so ayeke na droit ti sigingo na ambeti ni wala mbeni maboko ti mbeni zo so ayeke sara kua na iri ti zo ni.']

['Tongana mo sû atënë so kue pëpe, a lingbi ti sara si a mû ngoi mingi pëpe ti bâ lege ti tënë ti mo ni.']

['Tënë ti kiri ti bâ zo']

['Tongana mo yeke na mbeni hundango tënë wala mbeni tënë ti tene, tokua ni na e na lege ti mbeni lettre.']

How is alzheimer diagnosed?

Alzheimer's disease is diagnosed through a combination of methods, including a thorough medical evaluation, cognitive and neuropsychological tests, brain imaging, and the process of elimination of other possible causes.

1. Medical evaluation: A doctor will perform a physical examination and take a detailed medical history to rule out other possible causes of memory loss or cognitive decline, such as thyroid problems, vitamin deficiencies, or brain tumors.

2. Cognitive and neuropsychological tests: These tests assess memory, language, problem-solving, and other cognitive functions to determine the extent of cognitive impairment and to differentiate between normal age-related memory loss and dementia.

3. Brain imaging: Magnetic resonance imaging (MRI) or computed tomography (CT) scans can help identify structural changes in the brain that may indicate Alzheimer's disease.

Positron emission tomography (PET) scans can also be used to measure the levels of certain proteins associated with Alzheimer's disease.

4. Blood tests: Recent research has shown that certain blood tests can help diagnose Alzheimer's disease by measuring the levels of specific proteins or biomarkers associated with the disease.

5. Process of elimination: Since there is no single definitive test for Alzheimer's disease, diagnosis often involves ruling out other possible causes of dementia-like symptoms.

It is important to note that a definitive diagnosis of Alzheimer's disease can only be made after death through an examination of brain tissue.

However, current diagnostic methods can provide a high level of certainty for a clinical diagnosis while the person is still alive.

Early diagnosis is important for starting treatment and planning for the future.

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