What causes Alzheimer?

['Mä lembeti so']

Ye nyen ayeke na gunda ti kobela ti Alzheimer?

Kobela ti Alzheimer ayeke mbeni kobela so ayeke buba aye na yâ mongoli ti zo, na a yeke sala si lo girisa aye mingi, lo hinga ye nzoni pëpe, na salango ye ti lo ayeke gbian.

A hinga mbilimbili pëpe ye so ayeke na gunda ti kobela ti Alzheimer, me a bâ so a yeke aye tongana aye so aga na lege ti dungo, aye so angoro zo nga na dutingo ti zo.

Ambeni ye so alingbi ti sara si kobela ti Alzheimer amû ndo ayeke:

1. Aye so aga na lege ti mitele: A wara ambeni ye so ayeke na yâ mênë ti zo so alingbi ti sala si kobela ti Alzheimer amû ndo, mbilimbili ye so ayeke na yâ mênë ti zo so ayeke na mbeni ye so ayeke sala si mênë ti lo ayeke na ngangu mingi pëpe ti sala kusala nzoni.

Ngu ti zo: Tongana ngu ti zo ayeke gue na li ni, lo yeke wara kobela ti Alzheimer mingi ahon ti kozo.

3. Azo ti sewa ni: Tongana mbeni zo ti sewa ni ayeke na kobela ti Alzheimer, a lingbi ti sala si kpale ni akiri aga ngangu mingi.

4. Akä ti li: Tongana mbeni zo awara akä ti li kozoni, mbilimbili ala so asala si lo hinga ndo pëpe, ye so alingbi ti sala si lo wara kobela ti Alzheimer.

5 Akpale ti bê: Ambeni kobela tongana tension, cholestérol na diabète alingbi ti sara si zo awara kobela ti Alzheimer.

6 Aye so andu dutingo ti zo: Dutingo ti zo so aduti gi place oko, nzoni kobe pëpe nga na salango ye pëpe na lege ti li ti lo alingbi ti sala si kobela ti Alzheimer akiri aga ngangu mingi.

7. A lingbi ti sala si mbeni ye so ayeke na yâ mongoli ti zo asuku na so ayeke gue lakue na li ni aga kobela ti Alzheimer.

8. Kota kpale ti yâ ti tele: Tongana yâ ti tele ti zo ayeke na lege ni pëpe ti zi asioni yorö so ayeke na yâ tele ti lo, a lingbi ti sala si kobela ti Alzheimer amaï.

9. Akete ye so a hiri ni plaque amyloïde nga na agbakuru so ayeke na yâ mongoli ti zo: Bungbingo ti akete ye so a hiri ni plaque amyloïde nga na agbakuru so ayeke na yâ mongoli ti zo ayeke mbeni ye so afa na gigi kobela ti Alzheimer, me a hinga nzoni kue pëpe kusala so ala yeke sala na yâ maïngo ti kobela ni.

A yeke kota ye ti hinga so ye so ayeke na gunda ti kobela ti Alzheimer ayeke ngangu mingi na a lingbi ti duti aye so kue si abungbi oko.

A ngbâ ti gi nda ti aye ti hinga nzoni mingi aye so ayeke na gunda ni nga ti sigigi na ayorö so alingbi biani ti kaï na kobela so.

['Atënë so a bâ na ndo ni']

PubMed/Medline https://www.nlm.nih.gov/databases/download/pubmed_medline.html

RefinedWeb https://arxiv.org/abs/2306.01116

Vellas B, Andrieu S, Cantet C, Dartigues JF, Gauthier S: Long-term changes in ADAS-cog: what is clinically relevant for disease modifying trials in Alzheimer? J Nutr Health Aging. , 11 (4): 338-41.

Braak E, Griffing K, Arai K, Bohl J, Bratzke H, Braak H: Neuropathology of Alzheimer's disease: what is new since A. Alzheimer? Eur Arch Psychiatry Clin Neurosci. 1999, 249 Suppl 3 (): 14-22.

Kovacs GG: Can Creutzfeldt-Jakob disease unravel the mysteries of Alzheimer? Prion. 2016, 10 (5): 369-376.

Cankurtaran M, Yavuz BB, Cankurtaran ES, Halil M, Ulger Z, Ariogul S: Risk factors and type of dementia: vascular or Alzheimer? Arch Gerontol Geriatr. , 47 (1): 25-34.

Mahami-Oskouei M, Hamidi F, Talebi M, Farhoudi M, Taheraghdam AA, Kazemi T, Sadeghi-Bazargani H, Fallah E: Toxoplasmosis and Alzheimer: can Toxoplasma gondii really be introduced as a risk factor in etiology of Alzheimer? Parasitol Res. 2016, 115 (8): 3169-74.

['Tënë ti ziango kamene na lê: tënë ti seni']

['A zia site so gi ti fa na ye na azo na ti mû wango na ala.']

['A lingbi a sala kusala pëpe na asango so a mû ti hinga wala ti kaï na mbeni kpale ti seni wala kobela, na a lingbi ala so aye ti wara wango ti kaïngo kobela teti ala mveni ahunda mbeni wanganga so ayeke na mbeti ti hinga ye na ndo ni.']

['Bâ so tongana a hunda na zo ti fa wungo ti azo so ayeke na mbeni kobela, a yeke ngangu ti tene lo fa tâ wungo ti azo ni.']

['Gi lakue wango ti wanganga ti mo wala mbeni wanganga so ahinga kua ti lo nzoni na ndo ti kobela ti mo. Zia lâ oko pëpe ti ke wango ti wanganga wala ti ku ti wara ni ndali ti mbeni ye so mo diko na ndo ti site so. Tongana mo bâ so mo yeke na yâ ti mbeni kpale ti seni, iri 911 wala gue hio na hôpital so ayeke nduru na mo.']

['Kengo tene: droit ti lo ti sala tene']

['Ndia ti Amerika na ndo droit ti sigingo na ambeti (Digital Millennium Copyright Act) ti ngu 1998, 17 U.S.C. § 512 (so a hiri ni DMCA) amû lege na azo so ayeke na droit ti sigingo na ambeti ti bâ wala ambeti so asigigi na ndo ti Internet ni adoro droit ti ala so ndia ti Amerika amû na ndo droit ti sigingo na ambeti amû lege na ala ti sala ni. ']

['Tongana mo pensé so mbeni ye so ayeke na ndo ti site ti e wala na yâ ti ambeni ye so e yeke sara andu droit ti mo ti batango ambeti ti e, mo (wala zo so mo sara kua na iri ti lo) alingbi ti tokua na e mbeni mbeti ti hunda ti tene a zi ni wala a kanga lege na mo ti wara ni.']

['A lingbi a tokua ambeti ni na lege ti mbeni lettre so a sû na ndo ti ordinateur wala na lege ti mbeni téléphone (bâ mbage "A-adresse ti téléphone").']

['Ndia ti DMCA ahunda ti tene na yâ ti mbeti ti mo so a tene mbeni zo asara mbeni ye so ake ndia ti droit ti batango ambeti, mo zia atënë so ge: (1) fango peko ti kua so ndia ti batango ambeti ni ake ni; (2) fango peko ti aye so a tene a sara ye ti ke ndia ti batango ambeti ni nga na atënë so alingbi ti mû lege na e ti wara aye ni so; (3) asango ti mo ti wara mo, so andu adresse ti mo, numéro ti téléphone ti mo nga na adresse ti e-mail ti mo; (4) mbeni tënë so mo tene na bê ti mo kue so tënë ti aye ni so mo dema tere dä so ayeke pëpe tënë ti zo so ayeke na droit ti batango ambeti ni, wala zo so ayeke sara kua na iri ti lo, wala ndia ti kodoro ti mo.']

['(5) Mo sû maboko ti mo na gbe ti ngbanga ti mvene na mo tene so atënë so ayeke na yâ ti mbeti ni ayeke tâ tënë nga so mo yeke na ngangu ti sara si a bata droit ti mo ti sigingo na ambeti so a tene a doro ni.']

['Nga (6) mbeni maboko ti zo so ayeke na droit ti sigingo na ambeti ni wala mbeni maboko ti mbeni zo so ayeke sara kua na iri ti zo ni.']

['Tongana mo sû atënë so kue pëpe, a lingbi ti sara si a mû ngoi mingi pëpe ti bâ lege ti tënë ti mo ni.']

['Tënë ti kiri ti bâ zo']

['Tongana mo yeke na mbeni hundango tënë wala mbeni tënë ti tene, tokua ni na e na lege ti mbeni lettre.']

What causes alzheimer?

Alzheimer's disease is a progressive neurodegenerative disorder that primarily affects the brain, causing memory loss, cognitive decline, and behavioral changes.

The exact cause of Alzheimer's disease is not fully understood, but it is believed to result from a combination of genetic, environmental, and lifestyle factors.

Some of the factors that may contribute to the development of Alzheimer's disease include:

1. Genetics: Certain genes have been identified that increase the risk of developing Alzheimer's disease, particularly the apolipoprotein E (APOE) gene.

2. Age: The risk of developing Alzheimer's disease increases with age, with most people being diagnosed after the age of 65.

3. Family history: Having a family history of Alzheimer's disease may increase the risk of developing the condition.

4. Head injuries: A history of head injuries, particularly those that result in loss of consciousness, may increase the risk of Alzheimer's disease.

5. Cardiovascular risk factors: Conditions such as high blood pressure, high cholesterol, and diabetes may increase the risk of developing Alzheimer's disease.

6. Lifestyle factors: A sedentary lifestyle, poor diet, and lack of mental stimulation may increase the risk of Alzheimer's disease.

7. Inflammation: Chronic inflammation in the brain may contribute to the development of Alzheimer's disease.

8. Oxidative stress: An imbalance between the production of free radicals and the body's ability to detoxify them may contribute to the development of Alzheimer's disease.

9. Amyloid plaques and neurofibrillary tangles: The accumulation of amyloid plaques and neurofibrillary tangles in the brain is a hallmark of Alzheimer's disease, but the role they play in the development of the condition is not fully understood.

It is important to note that the cause of Alzheimer's disease is complex and likely involves a combination of these factors.

Research is ongoing to better understand the underlying mechanisms and develop effective treatments for this devastating condition.

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['Na ndo ni']

['Na yâ ti BioMedLib, a yeke sala kusala na a-ordinateur so ayeke sala kua gi na ndo ti tele ti ala mveni (na lege ti kode ti mandango ye na lege ti masini) ti leke ahundango tënë na akiringo tënë so a zia na tele ti mba.']

['E to nda ni na ambeti ti senda-ye kutu 35 so ayeke na yâ ti ambeti-sango so a iri ni PubMed/Medline nga na ambeni site ti e so a iri ni RefinedWeb.']

['Bâ "References" nga na "Disclaimer".']