Kode ti kaïngo kobela ti cancer ti kota yâ ayeke so wa?
Pathophysiologie ti cancer ti colon aye ti sara tënë ti aye so ayeke na gunda ti cancer ni nga na aye so ayeke sara si lo yeke maï.
Kanga ti yâ ti zo, wala cancer ti yâ ti lo, ayeke mbeni kobela so ayeke to nda ni na yâ ti kota yâ ti lo.
Mingi ni, a to nda ni tongana mbeni ye so akono na yâ ti tele ti zo, na so tongana ngoi ayeke hon alingbi ti ga cancer.
Aye mingi ayeke sala ngangu na ndo seni ti zo na yâ kota yâ ti lo, aye tongana gbiango ye so ayeke na yâ mênë ti zo, kobela ti yâ ti lo nga na aye so angoro lo.
A lingbi ti si so ambeni ye achangé na yâ ti acellule ti yâ ti koli, na a sara si acellule ni ayeke kono na ayeke kangbi tere kirikiri.
A lingbi ti wara agbiango ye so na yâ mênë ti zo wala a wara ni na lege ti kobela, na ala lingbi ti sala ngangu na ndo a-gène nde nde so ayeke sala kusala na yâ maïngo ti acellule, kangbingo ti ala, nga na lekengo ala.
Ti tene kobela ti colon asara zo, a lingbi lo nyon sämba mingi.
Tongana mbeni ye ayeke na yâ ti tere ti zo aninga, a lingbi ti sara si ambeni ye asigigi na yâ ti tere ti zo ti sara si acellule amaï na akangbi tere, na ye so alingbi ti sara si lo wara cancer.
Aye so angoro zo tongana kobe so lo yeke te, lege so lo yeke duti na fini ti lo nga ambeni ye so lo yeke te alingbi nga ti sara si lo wara cancer ti kota yâ.
Na tapande, a bâ so tengo gbâ ti bengba nyama nga na ambeni nyama so a leke ni alingbi ti sara si zo awara kobela ti cancer ti kota yâ.
Ambeni ye nde tongana tengo ye ahon ndo ni, nyongo manga nga na sarango ngia ti awanguru pëpe alingbi nga ti sara si kobela ni akiri aga ngangu.
Tongana cancer ti colon abâ gigi awe, lo lingbi ti gue na yâ ti ambeni stade nde nde, a londo na kozo stade ni so angbâ gi na yâ ti colon ti si na mbeni stade ni so ague na li ni mingi na so cancer ni amû ambeni mbage ti tere ti zo.
A-cellule ti cancer ni alingbi ti lï na yâ ti ambeni mbage ti tere ti zo so ayeke nduru na lo, nga ala lingbi ti mû yâ ti mênë ti gue na ambeni ndo so ayo, na tapande foie wala afufu.
Ti kaï na kobela ti cancer ti yâ ti kota kamba, a yeke hunda ti tene a sara opération, a mû yorö ti chimiothérapie nga a mû mbeni yorö ti singa.
Ti tene kobela ti cancer ti colon ague na li ni hio, a lingbi a gi ti hinga ni hio nga a kaï ni hio.
Tongana a yeke gi nda ti ye na yâ ti kota dû ti abio ti zo lakue, a lingbi ti mû maboko ti hinga kobela ti cancer ti kota dû ti abio na ngoi so a to nda ni hio, na ngoi so a lingbi ti sava ni hio.
Vidal-Vanaclocha F: The liver prometastatic reaction of cancer patients: implications for microenvironment-dependent colon cancer gene regulation. Cancer Microenviron. 2011, 4 (2): 163-80.
Yagi T, Kubota E, Koyama H, Tanaka T, Kataoka H, Imaeda K, Joh T: Glucagon promotes colon cancer cell growth via regulating AMPK and MAPK pathways. Oncotarget. 2018, 9 (12): 10650-10664.
Sharma SH, Thulasingam S, Nagarajan S: Terpenoids as anti-colon cancer agents - A comprehensive review on its mechanistic perspectives. Eur J Pharmacol. 2017, 795 (): 169-178.
Keshk WA, Zineldeen DH, Wasfy RE, El-Khadrawy OH: Fatty acid synthase/oxidized low-density lipoprotein as metabolic oncogenes linking obesity to colon cancer via NF-kappa B in Egyptians. Med Oncol. 2014, 31 (10): 192.
Dongfeng D, An C, Shujia P, Jikai Y, Tao Y, Rui D, Kai T, Yafeng C, Jianguo L, Xilin D: Explanation of colon cancer pathophysiology through analyzing the disrupted homeostasis of bile acids. Afr Health Sci. 2014, 14 (4): 925-8.
Tammali R, Ramana KV, Srivastava SK: Aldose reductase regulates TNF-alpha-induced PGE2 production in human colon cancer cells. Cancer Lett. 2007, 252 (2): 299-306.
['Tënë ti ziango kamene na lê: tënë ti seni']
['A zia site so gi ti fa na ye na azo na ti mû wango na ala.']
['A lingbi a sala kusala pëpe na asango so a mû ti hinga wala ti kaï na mbeni kpale ti seni wala kobela, na a lingbi ala so aye ti wara wango ti kaïngo kobela teti ala mveni ahunda mbeni wanganga so ayeke na mbeti ti hinga ye na ndo ni.']
['Bâ so tongana a hunda na zo ti fa wungo ti azo so ayeke na mbeni kobela, a yeke ngangu ti tene lo fa tâ wungo ti azo ni.']
['Gi lakue wango ti wanganga ti mo wala mbeni wanganga so ahinga kua ti lo nzoni na ndo ti kobela ti mo. Zia lâ oko pëpe ti ke wango ti wanganga wala ti ku ti wara ni ndali ti mbeni ye so mo diko na ndo ti site so. Tongana mo bâ so mo yeke na yâ ti mbeni kpale ti seni, iri 911 wala gue hio na hôpital so ayeke nduru na mo.']
['Kengo tene: droit ti lo ti sala tene']
['Ndia ti Amerika na ndo droit ti sigingo na ambeti (Digital Millennium Copyright Act) ti ngu 1998, 17 U.S.C. § 512 (so a hiri ni DMCA) amû lege na azo so ayeke na droit ti sigingo na ambeti ti bâ wala ambeti so asigigi na ndo ti Internet ni adoro droit ti ala so ndia ti Amerika amû na ndo droit ti sigingo na ambeti amû lege na ala ti sala ni. ']
['Tongana mo pensé so mbeni ye so ayeke na ndo ti site ti e wala na yâ ti ambeni ye so e yeke sara andu droit ti mo ti batango ambeti ti e, mo (wala zo so mo sara kua na iri ti lo) alingbi ti tokua na e mbeni mbeti ti hunda ti tene a zi ni wala a kanga lege na mo ti wara ni.']
['A lingbi a tokua ambeti ni na lege ti mbeni lettre so a sû na ndo ti ordinateur wala na lege ti mbeni téléphone (bâ mbage "A-adresse ti téléphone").']
['Ndia ti DMCA ahunda ti tene na yâ ti mbeti ti mo so a tene mbeni zo asara mbeni ye so ake ndia ti droit ti batango ambeti, mo zia atënë so ge: (1) fango peko ti kua so ndia ti batango ambeti ni ake ni; (2) fango peko ti aye so a tene a sara ye ti ke ndia ti batango ambeti ni nga na atënë so alingbi ti mû lege na e ti wara aye ni so; (3) asango ti mo ti wara mo, so andu adresse ti mo, numéro ti téléphone ti mo nga na adresse ti e-mail ti mo; (4) mbeni tënë so mo tene na bê ti mo kue so tënë ti aye ni so mo dema tere dä so ayeke pëpe tënë ti zo so ayeke na droit ti batango ambeti ni, wala zo so ayeke sara kua na iri ti lo, wala ndia ti kodoro ti mo.']
['(5) Mo sû maboko ti mo na gbe ti ngbanga ti mvene na mo tene so atënë so ayeke na yâ ti mbeti ni ayeke tâ tënë nga so mo yeke na ngangu ti sara si a bata droit ti mo ti sigingo na ambeti so a tene a doro ni.']
['Nga (6) mbeni maboko ti zo so ayeke na droit ti sigingo na ambeti ni wala mbeni maboko ti mbeni zo so ayeke sara kua na iri ti zo ni.']
['Tongana mo sû atënë so kue pëpe, a lingbi ti sara si a mû ngoi mingi pëpe ti bâ lege ti tënë ti mo ni.']
['Tënë ti kiri ti bâ zo']
['Tongana mo yeke na mbeni hundango tënë wala mbeni tënë ti tene, tokua ni na e na lege ti mbeni lettre.']
What is pathophysiology of colon cancer?
The pathophysiology of colon cancer refers to the underlying mechanisms and processes that lead to the development and progression of colon cancer.
Colon cancer, also known as colorectal cancer, is a type of cancer that begins in the colon or rectum, which are parts of the large intestine.
It typically starts as a growth called a polyp, which can develop into cancer over time.
The pathophysiology of colon cancer involves several factors, including genetic mutations, inflammation, and environmental factors.
Genetic mutations can occur in the DNA of colon cells, leading to uncontrolled cell growth and division.
These mutations can be inherited or acquired, and they can affect various genes involved in cell growth, division, and repair.
Inflammation in the colon, which can be caused by conditions such as inflammatory bowel disease, can also increase the risk of colon cancer.
Chronic inflammation can lead to the release of chemicals that promote cell growth and division, potentially leading to the development of cancer.
Environmental factors, such as diet, lifestyle, and exposure to certain chemicals, can also contribute to the development of colon cancer.
A diet high in red and processed meats, for example, has been linked to an increased risk of colon cancer.
Other factors, such as obesity, smoking, and lack of physical activity, can also increase the risk.
Once colon cancer develops, it can progress through several stages, from early-stage cancer that is confined to the colon to more advanced stages where the cancer has spread to other parts of the body.
The cancer cells can invade nearby tissues and organs, and may also spread through the lymphatic system or bloodstream to distant sites, such as the liver or lungs.
Treatment for colon cancer typically involves a combination of surgery, chemotherapy, and radiation therapy, depending on the stage and location of the cancer.
Early detection and treatment are key to improving outcomes, as colon cancer is often curable when caught in its early stages.
Regular screening, such as colonoscopy, can help detect colon cancer at its earliest stages, when it is most treatable.
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