E tele auala e mafai ona iloa ai le faamaʻi o le Alzheimer, e aofia ai le faia o se iloiloga māeʻaeʻa a le fomaʻi, o suʻesuʻega e iloa ai le mafaufau ma le neula, o le faia o ni ata o le faiʻai, ma le aveesea o isi māfuaaga e ono māfua ai.
1. Iloiloga faafomaʻi: E faia e se fomaʻi se suʻesuʻega i le tino ma faamaumauina le talaaga o le maʻi ina ia iloa ai po o ā nisi māfuaaga e ono māfua ai ona lē manatua lelei mea po o le faaitiitia o le mafaufau, e pei o faafitauli i le thyroid, le lē lava o vaitamini, po o le maʻi e tupu i le faiʻai.
2. Suʻesuʻega e iloa ai le mafaufau ma le neula: O nei suʻesuʻega e iloiloina ai le manatuaina o mea, le gagana, le foʻiaina o faafitauli, ma isi galuega e iloa ai le mafaufau ina ia iloa ai le telē o le faaletonu o le mafaufau ma iloa ai le eseesega o le lē manatuaina o mea e masani ona tutupu ona o le matua, ma le gasegase o le mafaufau.
3. O le faia o ni ata o le faiʻai: O le faia o ni ata e taʻu o le Magnetic resonance imaging (MRI) po o le computed tomography (CT) e mafai ona iloa ai ni suiga i le faiʻai e ono iloa ai le faamaʻi o le Alzheimer.
E mafai foʻi ona faaaogā le positron emission tomography (PET) e fua ai le tele o nisi o polotini e fesootaʻi atu i le faamaʻi o le Alzheimer.
4. Suʻesuʻega o le toto: Ua faaalia i suʻesuʻega talu ai nei e faapea, o nisi suʻesuʻega o le toto e mafai ona fesoasoani e iloa ai le faamaʻi o le Alzheimer e ala i le fuaina o le maualuga o polotini patino po o faailoga o le ola e fesootaʻi atu i le faamaʻi.
5. Faagasologa o le aveesea: Talu ai e leai se suʻesuʻega e tasi e iloa ai le faamaʻi o le Alzheimer, e masani lava ona aofia ai le aveesea o isi māfuaaga e ono māfua ai āuga e pei o le maʻi o le mafaufau.
E tāua le iloa, e faatoʻā mafai ona iloa le faamaʻi o le Alzheimer pe a uma le oti, e ala i le suʻesuʻeina o le faiʻai.
Peitaʻi, o metotia o loo iai i le taimi nei e mafai ona faamautinoa ai le maʻi o le tagata a o ola pea.
E tāua le vave iloa o le maʻi ina ia amata ai togafitiga ma fuafua ai le lumanaʻi.
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Rubin R: New Test to Help Diagnose Alzheimer Disease. JAMA. 2022, 327 (23): 2281.
[Blood Based Biomarker for Optimization of Early and Differential Diagnosis of Alzheimer's Dementia]. Fortschr Neurol Psychiatr. 2022, 90 (7-08): 326-335.
Kapp MB: Physicians' legal duties regarding the use of genetic tests to predict and diagnose Alzheimer disease. J Leg Med. 2000, 21 (4): 445-75.
Britschgi M, Wyss-Coray T: Blood protein signature for the early diagnosis of Alzheimer disease. Arch Neurol. 2009, 66 (2): 161-5.
Volicer L, Berman SA, Cipolloni PB, Mandell A: Persistent vegetative state in Alzheimer disease. Does it exist? Arch Neurol. 1997, 54 (11): 1382-4.
Imabayashi E, Saitoh Y, Tsukamoto T, Sakata M, Takano H: Combination of Astrogliosis and Phosphorylated Tau for the Preclinical Diagnosis of Alzheimer Disease Using 3-Dimensional Stereotactic Surface Projection Images With 18 F-THK5351. Clin Nucl Med. 2022, 47 (12): 1066-1068.
Martínez A, Lahiri DK, Giacobini E, Greig NH: Advances in Alzheimer therapy: understanding pharmacological approaches to the disease. Curr Alzheimer Res. 2009, 6 (2): 83-5.
['Faamatalaga: faafomaʻi']
['O lenei upega tafaʻilagi ua saunia mo na o le aʻoaʻoina ma le faailoaina atu o faamatalaga, ae e lē o se fautuaga faafomaʻi po o se auaunaga faapolofesa.']
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['Faamolemole ia mātau, o le neural net lea e maua ai tali i fesili, e lē saʻo pe a oo i fuainumera.']
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['E tatau ona auina atu faasilasilaga i se faiga tusitusia e ala i imeli (tagai i le vaega o le "Contact" mo le tuatusi imeli). ']
['O le DMCA e manaʻomia ai lau faʻasilasilaga o le faʻaleagaina o le puletaofia e aofia ai faʻamatalaga nei: (1) faʻamatalaga o le galuega faʻatagaina o loʻo faʻatatau i le faʻaleagaina o le puletaofia; (2) faʻamatalaga o le mea e ono solia ai ma faʻamatalaga lava e faʻatagaina ai matou ona maua le anotusi; (3) faʻamatalaga faʻafesoʻotaʻi mo oe, e aofia ai lau tuatusi, numera telefoni ma tuatusi imeli; (4) o se faʻamatalaga mai ia te oe o loʻo ia te oe le talitonuga lelei o le anotusi i le auala na faitio ai e le faʻatagaina e le pule o le puletaofia, poʻo lana sooupu, poʻo le faʻatinoina o soʻo se tulafono; ']
['(5) o se faamatalaga mai iā te oe, ua sainia i lalo o le faasalaga o le pepelo, e faapea o faamatalaga o loo i le faasilasilaga e saʻo ma e iai lau pule e faamalosia ai le aiā tatau lea o loo faapea mai ua solia; ']
['ma le (6) saini faaletino po o saini faaeletoroni a lē e ana le aiā tatau po o se tagata ua faatagaina e galue e fai ma sui o lē e ana le aiā tatau. ']
['Afai e lē o aofia uma faamatalaga o loo i luga, e ono faatuai ai ona iloilo lau faitioga.']
['Faafesootaʻi']
['Faamolemole lafo mai se imeli i so o se fesili / fautuaga.']
How is alzheimer diagnosed?
Alzheimer's disease is diagnosed through a combination of methods, including a thorough medical evaluation, cognitive and neuropsychological tests, brain imaging, and the process of elimination of other possible causes.
1. Medical evaluation: A doctor will perform a physical examination and take a detailed medical history to rule out other possible causes of memory loss or cognitive decline, such as thyroid problems, vitamin deficiencies, or brain tumors.
2. Cognitive and neuropsychological tests: These tests assess memory, language, problem-solving, and other cognitive functions to determine the extent of cognitive impairment and to differentiate between normal age-related memory loss and dementia.
3. Brain imaging: Magnetic resonance imaging (MRI) or computed tomography (CT) scans can help identify structural changes in the brain that may indicate Alzheimer's disease.
Positron emission tomography (PET) scans can also be used to measure the levels of certain proteins associated with Alzheimer's disease.
4. Blood tests: Recent research has shown that certain blood tests can help diagnose Alzheimer's disease by measuring the levels of specific proteins or biomarkers associated with the disease.
5. Process of elimination: Since there is no single definitive test for Alzheimer's disease, diagnosis often involves ruling out other possible causes of dementia-like symptoms.
It is important to note that a definitive diagnosis of Alzheimer's disease can only be made after death through an examination of brain tissue.
However, current diagnostic methods can provide a high level of certainty for a clinical diagnosis while the person is still alive.
Early diagnosis is important for starting treatment and planning for the future.
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['E tusa o le']
['E faaaogā e le BioMedLib ni komepiuta (machine-learning algorithms) e faia ai ni fesili ma ni tali.']
['E amata i le 35 miliona lomiga faafomaʻi o le PubMed/Medline.']
['Tagaʻi i le "Faamatalaga" ma le "Faamatalaga".']
