How is Alzheimer diagnosed?

Teerera peji iri

Chirwere cheAlzheimer chinoonekwa sei?

Chirwere cheAlzheimer chinoongororwa nenzira dzakasiyana-siyana, kusanganisira kuongororwa zvakadzama kwechiremba, kuongororwa kwepfungwa uye kwepfungwa, kuongororwa kweuropi, uye kubviswa kwezvimwe zvinogona kukonzera chirwere chacho.

1. Kuongororwa nezvokurapa: Chiremba achaita ongororo yomuviri ndokutora nhoroondo yezvokurapa kuti abvise zvimwe zvinogona kukonzera kurasikirwa nokurangarira kana kuti kuderera kwekuziva, zvakadai sezvinetso zve thyroid, kushomeka kwemavitamini, kana kuti bundu reuropi.

2. Kuongorora kwepfungwa uye kwepfungwa: Kuongorora uku kunoongorora ndangariro, mutauro, kugadzirisa zvinetso, uye mamwe mabasa ekuziva kuti uone kukura kwekukanganiswa kwekuziva uye kusiyanisa pakati pekurasikirwa kwekurangarira kunoenderana nezera uye dementia.

3. Kuongorora uropi: Kuongorora uropi uchishandisa magnetic resonance imaging (MRI) kana kuti computed tomography (CT) kunogona kubatsira kuziva kuchinja kunoita uropi kunogona kuratidza kuti une chirwere cheAlzheimer.

Positron emission tomography (PET) scans dzinogonawo kushandiswa kuyera mwero wemamwe mapuroteni anobatanidzwa nechirwere cheAlzheimer.

4. Ongororo dzeropa: Ongororo dzichangobva kuitwa dzakaratidza kuti mimwe miedzo yeropa inogona kubatsira kuziva chirwere cheAlzheimer kupfurikidza nokuyera uwandu hwemapuroteni chaiwo kana kuti zviratidzo zvipenyu zvine chokuita nechirwere chacho.

5. Nzira yokubvisa nayo: Sezvo pasina bvunzo imwe chete yechokwadi yechirwere cheAlzheimer, kuongorora kazhinji kazhinji kunobatanidza kubvisa zvimwe zvikonzero zvinobvira zvezviratidzo zvakafanana nedementia.

Zvakakosha kucherechedza kuti kuongororwa kwechokwadi kwechirwere cheAlzheimer kunogona kuitwa bedzi pashure porufu kupfurikidza nokuongororwa kwehuropi.

Zvisinei, nzira dzazvino dzokurapa dzinogona kupa mwero wakakwirira wokuva nechokwadi chokurapwa apo munhu wacho achiri mupenyu.

Kuongororwa nokukurumidza kunokosha nokuda kwokutanga kurapwa uye kuronga nokuda kwenguva yemberi.

Mashoko okufananidzira

PubMed/Medline https://www.nlm.nih.gov/databases/download/pubmed_medline.html

RefinedWeb https://arxiv.org/abs/2306.01116

Liu SS, Zhu SQ: [Correlation between Alzheimer disease and cataract]. Zhonghua Yan Ke Za Zhi. 2017, 53 (4): 314-316.

Gauthier S: Practical guidelines for the antemortem diagnosis of senile dementia of the Alzheimer type. Prog Neuropsychopharmacol Biol Psychiatry. 1985, 9 (5-6): 491-5.

Rubin R: New Test to Help Diagnose Alzheimer Disease. JAMA. 2022, 327 (23): 2281.

[Blood Based Biomarker for Optimization of Early and Differential Diagnosis of Alzheimer's Dementia]. Fortschr Neurol Psychiatr. 2022, 90 (7-08): 326-335.

Kapp MB: Physicians' legal duties regarding the use of genetic tests to predict and diagnose Alzheimer disease. J Leg Med. 2000, 21 (4): 445-75.

Britschgi M, Wyss-Coray T: Blood protein signature for the early diagnosis of Alzheimer disease. Arch Neurol. 2009, 66 (2): 161-5.

Volicer L, Berman SA, Cipolloni PB, Mandell A: Persistent vegetative state in Alzheimer disease. Does it exist? Arch Neurol. 1997, 54 (11): 1382-4.

Imabayashi E, Saitoh Y, Tsukamoto T, Sakata M, Takano H: Combination of Astrogliosis and Phosphorylated Tau for the Preclinical Diagnosis of Alzheimer Disease Using 3-Dimensional Stereotactic Surface Projection Images With 18 F-THK5351. Clin Nucl Med. 2022, 47 (12): 1066-1068.

Martínez A, Lahiri DK, Giacobini E, Greig NH: Advances in Alzheimer therapy: understanding pharmacological approaches to the disease. Curr Alzheimer Res. 2009, 6 (2): 83-5.

Kurambidzwa kwebasa: zvokurapa

Nzvimbo iyi yepaIndaneti inopiwa nokuda kwezvinangwa zvedzidzo uye zvemashoko chete uye haisi kupa mazano ezvokurapa kana kuti mabasa ehunyanzvi.

Mashoko anopiwa haafaniri kushandiswa kuongorora kana kuti kurapa chinetso cheutano kana kuti chirwere, uye avo vanotsvaka mazano ezvokurapa vanofanira kubvunza chiremba ane rezinesi.

Ndapota cherechedzai kuti neural net iyo inogadzira mhinduro dzemibvunzo, haina kururama zvikuru kana iri nyaya yenhamba. Somuenzaniso, nhamba yevanhu vanoonekwa vaine chirwere chakati.

Nguva dzose tsvaka zano rachiremba wako kana mumwe mupi wezvoutano akakodzera pamusoro pemamiriro ezvinhu ezvokurapa. Usambofa wakaregeredza zano rezvokurapa rehunyanzvi kana kunonoka kuritsvaka nemhaka yechinhu chipi nechipi chawakaverenga pawebsite ino. Kana uchifunga kuti unogona kuva nenjodzi yezvokurapa, fonera 911 kana kuenda kukamuri rokukurumidzira riri pedyo nokukurumidza. Hapana ukama hwechiremba nemurwere hunogadzirwa newebhusaiti ino kana kushandiswa kwayo. NeBioMedLib kana vashandi vayo, kana chero mupiro kune iyi webhusaiti, haitauri chero zvirevo, zvakataurwa kana kuti zvataurwa, maererano neruzivo rwunopihwa pano kana kushandiswa kwayo.

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How is alzheimer diagnosed?

Alzheimer's disease is diagnosed through a combination of methods, including a thorough medical evaluation, cognitive and neuropsychological tests, brain imaging, and the process of elimination of other possible causes.

1. Medical evaluation: A doctor will perform a physical examination and take a detailed medical history to rule out other possible causes of memory loss or cognitive decline, such as thyroid problems, vitamin deficiencies, or brain tumors.

2. Cognitive and neuropsychological tests: These tests assess memory, language, problem-solving, and other cognitive functions to determine the extent of cognitive impairment and to differentiate between normal age-related memory loss and dementia.

3. Brain imaging: Magnetic resonance imaging (MRI) or computed tomography (CT) scans can help identify structural changes in the brain that may indicate Alzheimer's disease.

Positron emission tomography (PET) scans can also be used to measure the levels of certain proteins associated with Alzheimer's disease.

4. Blood tests: Recent research has shown that certain blood tests can help diagnose Alzheimer's disease by measuring the levels of specific proteins or biomarkers associated with the disease.

5. Process of elimination: Since there is no single definitive test for Alzheimer's disease, diagnosis often involves ruling out other possible causes of dementia-like symptoms.

It is important to note that a definitive diagnosis of Alzheimer's disease can only be made after death through an examination of brain tissue.

However, current diagnostic methods can provide a high level of certainty for a clinical diagnosis while the person is still alive.

Early diagnosis is important for starting treatment and planning for the future.

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