What causes Alzheimer?

Teerera peji iri

Chii chinokonzera chirwere cheAlzheimer?

Chirwere cheAlzheimer chirwere chinopfuurira chinokanganisa uropi chinonyanya kukanganisa uropi, chichikonzera kurasikirwa ndangariro, kuderera kwekuziva, uye kuchinja kwetsika.

Chikonzero chaicho chechirwere cheAlzheimer hachisati chanyatsonzwisiswa, asi chinofungidzirwa kuti chinokonzerwa nezvinhu zvinobva muchibereko, zvakatipoteredza, uye mararamiro.

Zvimwe zvezvinhu zvingaita kuti pave nechirwere cheAlzheimer zvinosanganisira:

1. Genetics: Mamwe majini akaonekwa anowedzera ngozi yokuva nechirwere cheAlzheimer's, zvikurukuru jeni reapolipoprotein E (APOE).

2. Zera: Ngozi yokuva nechirwere cheAlzheimer inowedzera nezera, uye vanhu vakawanda vanoonekwa vava nemakore anopfuura 65.

3. Nhoroondo yemhuri: Kuva nenhoroondo yemhuri yechirwere cheAlzheimer kunogona kuwedzera ngozi yokuva nechirwere ichi.

4. Kukuvadzwa mumusoro: Nhoroondo yokukuvadzwa mumusoro, zvikurukuru uko kunoguma nokurasikirwa nokuziva, kunogona kuwedzera ngozi yechirwere cheAlzheimer.

5. Zvinhu zvinokonzera chirwere chemwoyo: Zvinhu zvakadai sokukwirira kweropa, cholesterol yakakwirira, uye chirwere cheshuga zvinogona kuwedzera ngozi yokuva nechirwere cheAlzheimer.

6. Zvinhu zvinoita kuti munhu ararame upenyu hwakanaka: Kurarama upenyu husina basa, kudya zvisina kunaka, uye kusava nechinangwa chendangariro zvinogona kuwedzera ngozi yechirwere cheAlzheimer.

7. Kuzvimba: Kuzvimba kusingaperi muuropi kungaita kuti pave nechirwere cheAlzheimer.

8. Oxidative stress: Kusaenzana pakati pokugadzirwa kwe free radicals uye mano omuviri okuzvibvisa kunogona kukonzera chirwere cheAlzheimer.

9. Amyloid plaques uye neurofibrillary tangles: Kuunganidzwa kweamyloid plaques uye neurofibrillary tangles muuropi chiratidzo chechirwere cheAlzheimer's, asi basa ravanoita mukukura kwechirwere ichi harina kunyatsonzwisiswa.

Zvinokosha kucherechedza kuti chinokonzera chirwere cheAlzheimer chakaoma kunzwisisa uye zvichida chinobatanidza zvinhu izvi.

Kutsvakurudza kuri kuenderera mberi kuti vanzwisise zviri nani mashandiro acho uye kuti vagadzire mishonga inoshanda pakurapa chirwere ichi chinokuvadza.

Mashoko okufananidzira

PubMed/Medline https://www.nlm.nih.gov/databases/download/pubmed_medline.html

RefinedWeb https://arxiv.org/abs/2306.01116

Vellas B, Andrieu S, Cantet C, Dartigues JF, Gauthier S: Long-term changes in ADAS-cog: what is clinically relevant for disease modifying trials in Alzheimer? J Nutr Health Aging. , 11 (4): 338-41.

Braak E, Griffing K, Arai K, Bohl J, Bratzke H, Braak H: Neuropathology of Alzheimer's disease: what is new since A. Alzheimer? Eur Arch Psychiatry Clin Neurosci. 1999, 249 Suppl 3 (): 14-22.

Kovacs GG: Can Creutzfeldt-Jakob disease unravel the mysteries of Alzheimer? Prion. 2016, 10 (5): 369-376.

Cankurtaran M, Yavuz BB, Cankurtaran ES, Halil M, Ulger Z, Ariogul S: Risk factors and type of dementia: vascular or Alzheimer? Arch Gerontol Geriatr. , 47 (1): 25-34.

Mahami-Oskouei M, Hamidi F, Talebi M, Farhoudi M, Taheraghdam AA, Kazemi T, Sadeghi-Bazargani H, Fallah E: Toxoplasmosis and Alzheimer: can Toxoplasma gondii really be introduced as a risk factor in etiology of Alzheimer? Parasitol Res. 2016, 115 (8): 3169-74.

Kurambidzwa kwebasa: zvokurapa

Nzvimbo iyi yepaIndaneti inopiwa nokuda kwezvinangwa zvedzidzo uye zvemashoko chete uye haisi kupa mazano ezvokurapa kana kuti mabasa ehunyanzvi.

Mashoko anopiwa haafaniri kushandiswa kuongorora kana kuti kurapa chinetso cheutano kana kuti chirwere, uye avo vanotsvaka mazano ezvokurapa vanofanira kubvunza chiremba ane rezinesi.

Ndapota cherechedzai kuti neural net iyo inogadzira mhinduro dzemibvunzo, haina kururama zvikuru kana iri nyaya yenhamba. Somuenzaniso, nhamba yevanhu vanoonekwa vaine chirwere chakati.

Nguva dzose tsvaka zano rachiremba wako kana mumwe mupi wezvoutano akakodzera pamusoro pemamiriro ezvinhu ezvokurapa. Usambofa wakaregeredza zano rezvokurapa rehunyanzvi kana kunonoka kuritsvaka nemhaka yechinhu chipi nechipi chawakaverenga pawebsite ino. Kana uchifunga kuti unogona kuva nenjodzi yezvokurapa, fonera 911 kana kuenda kukamuri rokukurumidzira riri pedyo nokukurumidza. Hapana ukama hwechiremba nemurwere hunogadzirwa newebhusaiti ino kana kushandiswa kwayo. NeBioMedLib kana vashandi vayo, kana chero mupiro kune iyi webhusaiti, haitauri chero zvirevo, zvakataurwa kana kuti zvataurwa, maererano neruzivo rwunopihwa pano kana kushandiswa kwayo.

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What causes alzheimer?

Alzheimer's disease is a progressive neurodegenerative disorder that primarily affects the brain, causing memory loss, cognitive decline, and behavioral changes.

The exact cause of Alzheimer's disease is not fully understood, but it is believed to result from a combination of genetic, environmental, and lifestyle factors.

Some of the factors that may contribute to the development of Alzheimer's disease include:

1. Genetics: Certain genes have been identified that increase the risk of developing Alzheimer's disease, particularly the apolipoprotein E (APOE) gene.

2. Age: The risk of developing Alzheimer's disease increases with age, with most people being diagnosed after the age of 65.

3. Family history: Having a family history of Alzheimer's disease may increase the risk of developing the condition.

4. Head injuries: A history of head injuries, particularly those that result in loss of consciousness, may increase the risk of Alzheimer's disease.

5. Cardiovascular risk factors: Conditions such as high blood pressure, high cholesterol, and diabetes may increase the risk of developing Alzheimer's disease.

6. Lifestyle factors: A sedentary lifestyle, poor diet, and lack of mental stimulation may increase the risk of Alzheimer's disease.

7. Inflammation: Chronic inflammation in the brain may contribute to the development of Alzheimer's disease.

8. Oxidative stress: An imbalance between the production of free radicals and the body's ability to detoxify them may contribute to the development of Alzheimer's disease.

9. Amyloid plaques and neurofibrillary tangles: The accumulation of amyloid plaques and neurofibrillary tangles in the brain is a hallmark of Alzheimer's disease, but the role they play in the development of the condition is not fully understood.

It is important to note that the cause of Alzheimer's disease is complex and likely involves a combination of these factors.

Research is ongoing to better understand the underlying mechanisms and develop effective treatments for this devastating condition.

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