How is Lung cancer diagnosed?

['Lalela lelikhasi']

Sifo semdlavuza wemaphaphu sibonwa njani?

Umdlavuza wemaphaphu utfolakala ngekutsi kuhlanganiswe luhlolo netindlela tekwelapha, letingafaka ekhatsi:

1. Umlandvo wekugula nekuhlolwa kwemtimba: Dokotela utawubuta ngetimphawu takho, umlandvo wekubhema, kanye nemlandvo wemndeni lonesifo semdlavuza wemaphaphu.

Batawuphindze bakuhlole kute babone timphawu talesifo.

2. Kuhlolwa kwekubona titfo temtimba: Kuhlolwa kwesifuba nge-X-ray kanye ne-computed tomography (CT) kuvame kusetjentiswa kute kutfolakale titfo temtimba temaphaphu kanye netakhiwo letitungeletile.

Lokuhlolwa kungakusita kutsi ubone tintfo letingekho kahle, njengemafinyila nobe tinhlayiya letingaveta kutsi unesifo semdlavuza wemaphaphu.

3. Kuhlolwa kwesikhwehlela: Kuhlolwa kwesikhwehlela sakho (lokukhwehlela lokusuka emaphashini) kusetjentiswa imicroscope kute kubukwe kutsi kute yini tinhlayiya temdlavuza.

4. Kuhlolwa kwesitfo semtimba: Kuhlolwa sikhumba semaphaphu bese kuhlolwa ngesibonakhulu kute kubonakale kutsi akunawo yini emaseli lanemdlavuza.

Loku kungentiwa ngekutsi kusetjentiswe i-bronchoscopy, i-needle biopsy, nobe i-surgical biopsy.

5. Bronchoscopy: Lithayiphi lelincane lelinekhamera lifakwa ngemphumulo nobe ngemlomo bese lingena emqaleni kute kuhlolwe tindlela tekuphefumula nemaphaphu.

Lenchubo ingaphindze isetjentiselwe kutsatsa emasampuli eticubu kute kwentiwe ema-biopsy.

6. Kuhlolwa ngemuno lomncane (Fine-needle aspiration [FNA]): Umuno lomncane ufakwa kulenhlayiya yemaphaphu kute kutsatfwe emasotja ayohlolwa.

7. Thoracentesis: Kusetjentiswa inaliti kute kukhishwe lolokusamanti emkhatsini wemaphaphu nelubondza lwesifuba, bese kuhlolwa kutsi kute yini tinhlayiya temdlavuza kulokusamanti.

8. Kuhlolwa kwengati: Nanobe luhlolo lwengati lungeke lukhone kubona kutsi umuntfu unemdlavuza wemaphaphu, kodvwa lungamsita kutsi abone simo semphilo yemuntfu futsi abone tintfo letingamkhombisa kutsi unemdlavuza.

9. Kuhlolwa kwematsambo, i-MRI, i-PET scan, kanye nalokunye: Lokuhlolwa kungasetjentiswa kute kubonakale kutsi umdlavuza sewundlulele nakuletinye tincenye temtimba yini.

Nangabe sekutfolakele kutsi unemdlavuza wemaphaphu, kungahle kwentiwe letinye tivivinyo kute kutfolakale kutsi sewukuliphi lizinga, lokuyintfo lengasita ekutsatseni tincumo tekwelashwa.

Loluhlolo lungafaka ekhatsi kuhlolwa kwemifanekiso, njengekuhlolwa kwebucopho nge-CT scan, kuhlola ematsambo nobe nge-positron emission tomography (PET).

['Tintfo letibhalwe phansi']

PubMed/Medline https://www.nlm.nih.gov/databases/download/pubmed_medline.html

RefinedWeb https://arxiv.org/abs/2306.01116

Zhou P, Lu F, Wang J, Wang K, Liu B, Li N, Tang B: A portable point-of-care testing system to diagnose lung cancer through the detection of exosomal miRNA in urine and saliva. Chem Commun (Camb). 2020, 56 (63): 8968-8971.

Ni J, Guo Z, Zhang L: [The diagnostic significance of single or combination lung cancer-related serum biomarkers in high risk lung cancer patients]. Zhonghua Nei Ke Za Zhi. 2016, 55 (1): 25-30.

Nishiyama N, Nakatani S, Iwasa R, Taguchi S, Inoue K, Kinoshita H: [Differential diagnosis between peripheral lung cancer invading the chest wall and chest-wall tumors]. Kyobu Geka. 1997, 50 (10): 893-7.

Kang C, Wang D, Zhang X, Wang L, Wang F, Chen J: Construction and Validation of a Lung Cancer Diagnostic Model Based on 6-Gene Methylation Frequency in Blood, Clinical Features, and Serum Tumor Markers. Comput Math Methods Med. 2021, 2021 (): 9987067.

Heydari F, Rafsanjani MK: A Review on Lung Cancer Diagnosis Using Data Mining Algorithms. Curr Med Imaging. 2021, 17 (1): 16-26.

Li L, Feng T, Zhang W, Gao S, Wang R, Lv W, Zhu T, Yu H, Qian B: MicroRNA Biomarker hsa-miR-195-5p for Detecting the Risk of Lung Cancer. Int J Genomics. 2020, 2020 (): 7415909.

Li B, Yuan Q, Zou YT, Su T, Lin Q, Zhang YQ, Shi WQ, Liang RB, Ge QM, Li QY, Shao Y: CA-125, CA-153, and CYFRA21-1 as clinical indicators in male lung cancer with ocular metastasis. J Cancer. 2020, 11 (10): 2730-2736.

Magee ND, Villaumie JS, Marple ET, Ennis M, Elborn JS, McGarvey JJ: Ex vivo diagnosis of lung cancer using a Raman miniprobe. J Phys Chem B. 2009, 113 (23): 8137-41.

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['Kwehluleka kufaka yonkhe lemininingwane lengenhla kungaholela ekubambelekeni kwekusetjentwa kwesikhalo sakho.']

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['Sicela usitfumelele i-email nganobe nguwuphi umbuto / umbono.']

How is lung cancer diagnosed?

Lung cancer is diagnosed through a combination of tests and procedures, which may include:

1. Medical history and physical examination: The doctor will ask about your symptoms, smoking history, and family history of lung cancer.

They will also perform a physical examination to check for any signs of the disease.

2. Imaging tests: Chest X-rays and computed tomography (CT) scans are commonly used to create detailed images of the lungs and surrounding structures.

These tests can help detect abnormalities, such as tumors or nodules, that may indicate the presence of lung cancer.

3. Sputum cytology: A sample of your sputum (mucus coughed up from the lungs) is examined under a microscope to look for cancer cells.

4. Biopsy: A sample of lung tissue is removed and examined under a microscope to determine if cancer cells are present.

This can be done through a bronchoscopy, needle biopsy, or surgical biopsy.

5. Bronchoscopy: A thin, lighted tube with a camera is inserted through the nose or mouth and down the throat to examine the airways and lungs.

This procedure can also be used to collect tissue samples for biopsy.

6. Fine-needle aspiration (FNA): A thin needle is inserted into the lung nodule or mass to collect a sample of cells for examination.

7. Thoracentesis: Fluid is removed from the space between the lungs and chest wall using a needle, and the fluid is then examined for cancer cells.

8. Blood tests: While blood tests alone cannot diagnose lung cancer, they can help determine the overall health of the patient and identify any abnormalities that may indicate the presence of cancer.

9. Bone scan, mri, pet scan, and other tests: These tests may be used to determine if the cancer has spread to other parts of the body.

Once lung cancer is diagnosed, additional tests may be performed to determine the stage of the cancer, which helps guide treatment decisions.

These tests may include more imaging tests, such as a CT scan of the brain, bone scan, or positron emission tomography (PET) scan.

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