What causes Alzheimer?

['Dengekeun kaca ieu']

Naon nu nyababkeun Alzheimer?

Panyakit Alzheimer nyaéta gangguan neurodegeneratif anu lumangsung sacara progresif nu utamana mangaruhan uteuk, ngabalukarkeun leungitna ingetan, turunna kognitif, sarta parobahan paripolah.

Anu nyababkeun panyakit Alzheimer téh teu pati dipikaharti, tapi dipercaya aya sababaraha faktor, nyaéta genetik, lingkungan, jeung gaya hirup.

Sababaraha faktor nu bisa ngabalukarkeun Alzheimer nyaéta:

1. Genetik: Aya gén nu bisa ngabalukarkeun panyakit Alzheimer, hususna gén apolipoprotein E (APOE).

2. Umur: Résiko meunang panyakit Alzheimer beuki nambahan lamun umurna beuki kolot, sabab lolobana jalma nu meunang panyakit ieu téh sanggeus umur 65 taun.

3. Sajarah kulawarga: Lamun aya kulawarga nu boga panyakit Alzheimer, bisa jadi leuwih gampang meunangkeun panyakit ieu.

4. Tatu sirah: Lamun aya nu pernah tatu sirah, utamana nu ngabalukarkeun leungitna kasadaran, bisa jadi leuwih gampang meunang panyakit Alzheimer.

5. Faktor résiko panyakit jantung jeung pembuluh darah: Kasakit kawas tekanan darah tinggi, koléstérol tinggi, jeung diabetes bisa ningkatkeun résiko panyakit Alzheimer.

6. Gaya hirup: Gaya hirup nu teu aktif, kadaharan nu goréng, jeung kurangna stimulasi méntal bisa ningkatkeun résiko panyakit Alzheimer.

7. Peradangan: Peradangan kronis dina uteuk bisa ngabalukarkeun panyakit Alzheimer.

8. Strés oksidatif: Lamun teu saimbang antara produksi radikal bébas jeung kamampuh awak pikeun ngaleungitkeun racunna, bisa jadi aya nu jadi panyakit Alzheimer.

9. Plak amiloid jeung neuron-neuron anu kajebak: Plak amiloid jeung neuron-neuron anu kajebak dina uteuk téh ciri panyakit Alzheimer, tapi teu pati dipikaharti kumaha peranna dina ieu panyakit.

Penting pikeun dicatet yén panyakit Alzheimer téh rumit sarta bisa jadi aya sababaraha hal nu ngabalukarkeunana.

Panalungtikan keur lumangsung pikeun leuwih paham kana mékanisme nu nyababkeunana sarta ngamekarkeun ubar nu éféktif pikeun panyakit nu matak cilaka ieu.

['Rujukan']

PubMed/Medline https://www.nlm.nih.gov/databases/download/pubmed_medline.html

RefinedWeb https://arxiv.org/abs/2306.01116

Vellas B, Andrieu S, Cantet C, Dartigues JF, Gauthier S: Long-term changes in ADAS-cog: what is clinically relevant for disease modifying trials in Alzheimer? J Nutr Health Aging. , 11 (4): 338-41.

Braak E, Griffing K, Arai K, Bohl J, Bratzke H, Braak H: Neuropathology of Alzheimer's disease: what is new since A. Alzheimer? Eur Arch Psychiatry Clin Neurosci. 1999, 249 Suppl 3 (): 14-22.

Kovacs GG: Can Creutzfeldt-Jakob disease unravel the mysteries of Alzheimer? Prion. 2016, 10 (5): 369-376.

Cankurtaran M, Yavuz BB, Cankurtaran ES, Halil M, Ulger Z, Ariogul S: Risk factors and type of dementia: vascular or Alzheimer? Arch Gerontol Geriatr. , 47 (1): 25-34.

Mahami-Oskouei M, Hamidi F, Talebi M, Farhoudi M, Taheraghdam AA, Kazemi T, Sadeghi-Bazargani H, Fallah E: Toxoplasmosis and Alzheimer: can Toxoplasma gondii really be introduced as a risk factor in etiology of Alzheimer? Parasitol Res. 2016, 115 (8): 3169-74.

['Bantahan: masalah médis']

['Situs wéb ieu ngan keur tujuan pendidikan jeung informasi, lain pikeun méré naséhat atawa jasa profésional.']

['Informasi nu disadiakeun di dieu teu kudu dipaké pikeun nangtukeun atawa ngubaran masalah kaséhatan atawa panyakit.']

['Punten perhatikeun yén jaringan saraf nu ngahasilkeun jawaban kana pananya, teu akurat lamun ngeunaan eusi numeris. contona, jumlah jalma nu didiagnosis kalawan panyakit husus.']

['Salawasna ménta naséhat ti dokter atawa panyadia kaséhatan nu mumpuni séjénna ngeunaan kaayaan médis. Ulah ngalalaworakeun naséhat médis profésional atawa nunda néangan éta kusabab hal nu geus maca dina ramatloka ieu. Lamun anjeun mikir anjeun bisa jadi boga kaayaan darurat médis, nelepon 911 atawa indit ka kamar darurat pangdeukeutna langsung.']

['Bantahan: hak cipta']

['Digital Millennium Copyright Act of 1998, 17 U.S.C. § 512 (DMCA) nyadiakeun jalan pikeun nu boga hak cipta nu percaya yén bahan nu muncul di Internet ngalanggar hak-hakna dina hukum hak cipta AS. ']

['Lamun anjeun percaya yén aya eusi atawa bahan nu disadiakeun dina situs wéb atawa jasa urang ngalanggar hak cipta anjeun, anjeun (atawa agén anjeun) bisa ngirimkeun béwara ka kami pikeun nyuhunkeun eusi atawa bahan éta dipiceun, atawa aksés ka éta diblokir.']

['Bewara kudu dikirimkeun ku email (tempo bagian "Kontak" pikeun alamat email).']

['DMCA merlukeun yén bewara Anjeun tina ngalanggar hak cipta disangka kaasup informasi di handap ieu: (1) pedaran karya nu hak ciptana nu subyek ngalanggar ngaku; (2) pedaran eusi nu disangka ngalanggar jeung informasi cukup pikeun ngidinan urang pikeun nomeran eusi; (3) informasi kontak pikeun anjeun, kaasup alamat anjeun, nomer telepon jeung alamat surélék; (4) pernyataan ku anjeun nu boga kapercayaan alus iman nu eusi dina ragam complaining ngeunaan teu otorisasi ku nu boga hak cipta, atawa agén anak, atawa ku operasi hukum nu mana wae; ']

['(5) pernyataan nu ditandatanganan ku Sadérék, nu ngajamin yén informasi nu aya dina éta surat téh bener jeung Sadérék boga wewenang pikeun ngabéla hak cipta nu diklaim dilanggar.']

['jeung (6) tanda tangan nu nyata atawa éléktronik nu boga hak cipta atawa jalma nu boga wewenang pikeun ngawakilan nu boga hak cipta. ']

['Lamun teu kaasup kabéh informasi di luhur, bisa ngalambatkeun panalungtikan keluhan.']

['Kontak']

['Mangga kirimkeun email ka kami lamun aya pertanyaan/saran.']

What causes alzheimer?

Alzheimer's disease is a progressive neurodegenerative disorder that primarily affects the brain, causing memory loss, cognitive decline, and behavioral changes.

The exact cause of Alzheimer's disease is not fully understood, but it is believed to result from a combination of genetic, environmental, and lifestyle factors.

Some of the factors that may contribute to the development of Alzheimer's disease include:

1. Genetics: Certain genes have been identified that increase the risk of developing Alzheimer's disease, particularly the apolipoprotein E (APOE) gene.

2. Age: The risk of developing Alzheimer's disease increases with age, with most people being diagnosed after the age of 65.

3. Family history: Having a family history of Alzheimer's disease may increase the risk of developing the condition.

4. Head injuries: A history of head injuries, particularly those that result in loss of consciousness, may increase the risk of Alzheimer's disease.

5. Cardiovascular risk factors: Conditions such as high blood pressure, high cholesterol, and diabetes may increase the risk of developing Alzheimer's disease.

6. Lifestyle factors: A sedentary lifestyle, poor diet, and lack of mental stimulation may increase the risk of Alzheimer's disease.

7. Inflammation: Chronic inflammation in the brain may contribute to the development of Alzheimer's disease.

8. Oxidative stress: An imbalance between the production of free radicals and the body's ability to detoxify them may contribute to the development of Alzheimer's disease.

9. Amyloid plaques and neurofibrillary tangles: The accumulation of amyloid plaques and neurofibrillary tangles in the brain is a hallmark of Alzheimer's disease, but the role they play in the development of the condition is not fully understood.

It is important to note that the cause of Alzheimer's disease is complex and likely involves a combination of these factors.

Research is ongoing to better understand the underlying mechanisms and develop effective treatments for this devastating condition.

Disclaimer: medical

This web site is provided for educational and informational purposes only and does not constitute providing medical advice or professional services.

The information provided should not be used for diagnosing or treating a health problem or disease, and those seeking personal medical advice should consult with a licensed physician.

Please note the neural net that generates answers to the questions, is specially inaccurate when it comes to numeric content. For example, the number of people diagnosed with a specific disease.

Always seek the advice of your doctor or other qualified health provider regarding a medical condition. Never disregard professional medical advice or delay in seeking it because of something you have read on this website. If you think you may have a medical emergency, call 911 or go to the nearest emergency room immediately. No physician-patient relationship is created by this web site or its use. Neither BioMedLib nor its employees, nor any contributor to this web site, makes any representations, express or implied, with respect to the information provided herein or to its use.

Disclaimer: copyright

The Digital Millennium Copyright Act of 1998, 17 U.S.C. § 512 (the “DMCA”) provides recourse for copyright owners who believe that material appearing on the Internet infringes their rights under U.S. copyright law. If you believe in good faith that any content or material made available in connection with our website or services infringes your copyright, you (or your agent) may send us a notice requesting that the content or material be removed, or access to it blocked. Notices must be sent in writing by email (see 'Contact' section for email address) . The DMCA requires that your notice of alleged copyright infringement include the following information: (1) description of the copyrighted work that is the subject of claimed infringement; (2) description of the alleged infringing content and information sufficient to permit us to locate the content; (3) contact information for you, including your address, telephone number and email address; (4) a statement by you that you have a good faith belief that the content in the manner complained of is not authorized by the copyright owner, or its agent, or by the operation of any law; (5) a statement by you, signed under penalty of perjury, that the information in the notification is accurate and that you have the authority to enforce the copyrights that are claimed to be infringed; and (6) a physical or electronic signature of the copyright owner or a person authorized to act on the copyright owner’s behalf. Failure to include all of the above information may result in the delay of the processing of your complaint.