How to treat Prostate cancer?

['ነዚ ገጽ ስምዓዮ']

መንሽሮ ፕሮስቴት ብኸመይ ይፍወስ?

ንናይ ፕሮስቴት ካንሰር ዝተፈላለዩ ናይ ሕክምና ኣማራጺታት ኣሎ፡ እዚ ድማ ኣብ ደረጃን ብርቱዕነትን ናይቲ ካንሰር፡ ከምኡ'ውን ኣብ ሓፈሻዊ ጥዕና ናይቲ ሕሙምን ውልቃዊ ምርጫታትን ይምርኮስ።

ገለ ልሙዳት ሕክምናታት እዞም ዝስዕቡ እዮም

1. ንጡፍ ምክትታል፡ እዚ ኣገባብ እዚ ኣብ ክንዲ ብኡንብኡ ሕክምና ምጅማር፡ ነቲ ካንሰር ብቀጻሊ ምምርማርን ምርመራን ብቐረባ ምክትታል የጠቓልል።

ንትሑት ሓደጋ ካንሰር ፕሮስቴት ዘለዎም ሰባት ድማ ክጠቅም ይኽእል እዩ።

2. መጥባሕቲ:- ፕሮስቴትቶሚ ናይ ፕሮስቴት ግራንዲ ንምውጻእ ዝግበር መጥባሕቲ እዩ።

ብክፉት መጥባሕቲ ወይ ብላፓሮስኮፒ (ንኣሽቱ መቑረጽትን ፍሉይ መሳርሒታትን ብምጥቃም) ክግበር ይከኣል።

3. ናይ ጨረር ሕክምና:- እዚ ሕክምና ናይ ካንሰር ዋህዮታት ንምቕታል ልዑል ጸዓት ዘለዎ ጨረር ይጥቀም።

እዚ ብደገ (ካብ ሓደ ካብ ሰብነት ወጻኢ ዘሎ ማሽን) ወይ ብውሽጢ (ኣብ ጥቓ እቲ መንሽሮ ብዝተገበረ መትከል) ክወሃብ ይኽእል።

ሆርሞን ቴራፒ:- እዚ ሕክምና እዚ ኣብ ኣካላት ናይ ደቂ ተባዕትዮ ሆርሞን (ኣንድሮጅን) መጠን የጉድል። እዚ ድማ ነቲ ናይ ፕሮስቴት ካንሰር ምዕባለ ከጉድሎ ወይ ደው ከብሎ ይኽእል።

ንበይኑ ወይ ምስ ካልኦት ሕክምናታት ብምውህሃድ ክጥቀም ይኽእል እዩ።

5. ኬሞተራፒ፡ እዚ ሕክምና እዚ ንናይ ካንሰር ዋህዮታት ንምቕታል መድሃኒታት ይጥቀም።

ናብ ካልእ ክፋል ናይ ኣካላት ዝተዘርገሐ ናይ ፕሮስቴት ካንሰር ንምፍዋስ ክውዕል ይኽእል እዩ።

6. ኢሙኖተራፒ:- እዚ ሕክምና እዚ ስርዓተ ምክልኻል ሕማም ንካንሰር ንምቅላስ ይሕግዝ።

ንካልእ ሕክምናታት ምላሽ ዘይሃበ ናይ ፕሮስቴት ካንሰር ክጥቀም ይኽእል።

7. ዒላማ ዝገበረ ሕክምና፡ እዚ ሕክምና እዚ ነቶም ናይ ካንሰር ዋህዮታት ክዓብዩን ክነብሩ ዝሕግዙ ፍሉያት ጂናት ወይ ፕሮቲናት ዒላማ ይገብር።

ንካልእ ሕክምናታት ምላሽ ዘይሃበ ናይ ፕሮስቴት ካንሰር ክጥቀም ይኽእል።

8. ክሪዮተራፒ (Cryotherapy): እዚ ሕክምና ኣዝዩ ብርቱዕ ቀዝሒ ብምጥቃም ንናይ ካንሰር ዋህዮታት የቐዝፎምን ይቐትሎምን።

ኣብ ናይ መጀመርያ ደረጃ ናይ ፕሮስቴት ካንሰር ወይ ድሕሪ ካልእ ሕክምናታት ተመሊሱ ንዝመጽእ ካንሰር ክውዕል ይኽእል እዩ።

9. ልዑል ጽዓት ዝተሓወሶ ናይ ድምጺ ሕክምና (HIFU): እዚ ሕክምና ናይ ካንሰር ዋህዮታት ንምሙቕቓዕን ንምጥፋእን ልዑል ፍሪኩዌንሲ ናይ ድምጺ ማዕበል ይጥቀም።

ኣብ ናይ መጀመርያ ደረጃ ናይ ፕሮስቴት ካንሰር ወይ ድሕሪ ካልእ ሕክምናታት ተመሊሱ ንዝመጽእ ካንሰር ክውዕል ይኽእል እዩ።

10. ንቑሕ ምጽባይ: እዚ ኣገባብ እዚ ነቲ ካንሰር ብቀጻሊ ምምርማርን ምርመራን ብቐረባ ምክትታል ዘጠቓልል ኮይኑ፡ ምልክታት ክሳብ ዘይተርኣየ ወይ ክሳብ ዘይተቐየረ ግን ሕክምና ኣይጅምርን እዩ።

ንብዝሒ ዕድመ ዘለዎም ደቂ ተባዕትዮ፡ ብነድሪ ካንሰር ፕሮስቴትን ካልኦት ከቢድ ናይ ጥዕና ጸገማትን፡ ክጥቀሙሉ ይኽእሉ እዮም።

ንነፍሲ ወከፍ ጉዳይ ዝምልከት ዝበለጸ ኣገባብ ንምውሳን ምስ ናይ ጥዕና ጉጅለ ብዛዕባ ኩሎም ኣማራጺታት ሕክምና ምዝርራብ ኣገዳሲ እዩ።

['መወከሲ']

PubMed/Medline https://www.nlm.nih.gov/databases/download/pubmed_medline.html

RefinedWeb https://arxiv.org/abs/2306.01116

Wang Y, Chen J, Wu Z, Ding W, Gao S, Gao Y, Xu C: Mechanisms of enzalutamide resistance in castration-resistant prostate cancer and therapeutic strategies to overcome it. Br J Pharmacol. 2021, 178 (2): 239-261.

Talkar SS, Patravale VB: Gene Therapy for Prostate Cancer: A Review. Endocr Metab Immune Disord Drug Targets. 2021, 21 (3): 385-396.

Šamija I, Fröbe A: CHALLENGES IN MANIPULATING IMMUNE SYSTEM TO TREAT PROSTATE CANCER. Acta Clin Croat. 2019, 58 (Suppl 2): 76-81.

Akaza H, Hinotsu S, Usami M, Ogawa O, Kagawa S, Kitamura T, Tsukamoto T, Naito S, Hirao Y, Murai M, Yamanaka H, Namiki M: The case for androgen deprivation as primary therapy for early stage disease: results from J-CaP and CaPSURE. J Urol. 2006, 176 (6 Pt 2): S47-9.

Abraham-Miranda J, Awasthi S, Yamoah K: Immunologic disparities in prostate cancer between American men of African and European descent. Crit Rev Oncol Hematol. 2021, 164 (): 103426.

de Vrij J, Willemsen RA, Lindholm L, Hoeben RC, Bangma CH, Barber C, Behr JP, Briggs S, Carlisle R, Cheng WS, Dautzenberg IJ, de Ridder C, Dzojic H, Erbacher P, Essand M, Fisher K, Frazier A, Georgopoulos LJ, Jennings I, Kochanek S, Koppers-Lalic D, Kraaij R, Kreppel F, Magnusson M, Maitland N, Neuberg P, Nugent R, Ogris M, Remy JS, Scaife M, Schenk-Braat E, Schooten E, Seymour L, Slade M, Szyjanowicz P, Totterman T, Uil TG, Ulbrich K, van der Weel L, van Weerden W, Wagner E, Zuber G: Adenovirus-derived vectors for prostate cancer gene therapy. Hum Gene Ther. 2010, 21 (7): 795-805.

Lee E, Ha S, Logan SK: Divergent Androgen Receptor and Beta-Catenin Signaling in Prostate Cancer Cells. PLoS One. 2015, 10 (10): e0141589.

['ናይ ተሓታትነት መግለጺ: ሕክምናዊ']

['እዚ ወብ ሳይት ንትምህርትን ሓበሬታን ጥራይ እዩ ተዋሂቡ: ሕክምናዊ ምኽሪ ወይ ሞያዊ ኣገልግሎት ንምሃብ ተባሂሉ እተዳለወ ድማ ኣይኰነን።']

['እቲ ሓበሬታ ንዝኾነ ናይ ጥዕና ጸገም ወይ ሕማም ንምፍላጥ ወይ ንምሕካም ክውዕል የብሉን፣ እቶም ውልቃዊ ናይ ሕክምና ምኽሪ ዝደልዩ ድማ ምስ ፍቓድ ዘለዎ ሓኪም ክማኸሩ ኣለዎም።']

['እቲ መልሲ ናይቶም ሕቶታት ዝህብ ኔቭራል ኔት፡ ብፍላይ ኣብ ቁጽሪ ዝተሞርኮሰ ሓበሬታ፡ ንኣብነት፡ ብዝሒ ናይቶም ዝተለኽፉ ሰባት ምስ ዝኸውን፡ ኣዝዩ ዘይቅኑዕ ምዃኑ ኣስተብህል።']

['ኩሉ ግዜ ብዛዕባ ናይ ጥዕና ኩነታትካ ምኽሪ ናይ ሓኪምካ ወይ ካልእ ብቑዕ ናይ ጥዕና ኣገልጋሊ ድለ። ኣብዚ መርበብ ሓበሬታ ዘንበብካዮ ነገር ምኽንያት ናይ ሞያ ናይ ሕክምና ምኽሪ ዕሽሽ ኣይትበል። ናይ ሕክምና ህጹጽ ኩነታት ከጋጥመካ ይኽእል እዩ ኢልካ እንተሓሲብካ 911 ደውል ወይ ናብ ዝቐረበ ህጹጽ ክፍሊ ህጹጽ ረድኤት ብቅልጡፍ ኪድ። እዚ መርበብ ሓበሬታ ወይ ኣጠቓቕምኡ ናይ ሓኪምን ሕሙምን ርክብ ኣይፈጥርን። BioMedLib ወይ ሰራሕተኛታቱ ወይ ዝኾነ ኣበርካቲ ናይዚ መርበብ ሓበሬታ እዚ ኣብዚ ዝተዋህበ ሓበሬታ ወይ ኣጠቓቕምኡ ብዝምልከት ዝኾነ ይኹን መግለጺ ወይ ውክልና ኣይህብን እዩ።']

['ናይ መሰል ተሓታትነት']

['ናይ 1998 ዲጂታል ሚሊኒየም ሕጊ መሰል ደራሲ 17 U.S.C. § 512 (the DMCA) ኣብ ኢንተርኔት ዝረአ ዘሎ ትሕዝቶ ብመሰረት ሕጊ መሰል ደራሲ ኣሜሪካ መሰሎም ዝጥሕስ እዩ ኢሎም ንዝኣምኑ ወነንቲ መሰል ደራሲ ይምልከት። ']

['ዝኾነ ትሕዝቶ ወይ ማተርያል ምስ ዌብሳይትና ወይ ኣገልግሎትና ብምትሕሓዝ ዝተዳለወ ንናይ መሰል ዋንነትካ ዝጥሕስ እዩ ኢልካ ብጽቡቕ እምነት እንተኣሚንካ፣ ንስኻ (ወይ ወኪልካ) ነቲ ትሕዝቶ ወይ ማተርያል ክውገድ ወይ ድማ ናብኡ ምእታው ክኽልከል ዝሓትት ምልክታ ክትልእኸልና ትኽእል ኢኻ።']

['እቲ ምልክታ ብጽሑፍ ብኢሜይል ክለኣኽ ኣለዎ (ናይ ኢሜይል ኣድራሻ ንምርካብ ኣብ "Contact" ዝብል ክፋል ተመልከት) ።']

['እቲ DMCA እዚ ዝስዕብ ሓበሬታታት ክካተት ይሓትት፡ (1) መግለጺ ናይቲ ግህሰት ተፈጻምነት ኣለዎ ተባሂሉ ዝሕመ፡ (2) መግለጺ ናይቲ ግህሰት ተፈጻምነት ኣለዎ ተባሂሉ ዝሕመ ትሕዝቶን ነቲ ትሕዝቶ ክንረኽቦ ዘኽእለና እኹል ሓበሬታን (3) ናይ ርክብ ሓበሬታ፡ እንተላይ ኣድራሻኻ፡ ቁጽሪ ተሌፎንካን ናይ ኢመይል ኣድራሻኻን (4) እቲ ትሕዝቶ በቲ ጥርዓን ዝቐርበሉ መገዲ በቲ በዓል መሰል፡ ወይ ወኪሉ ወይ ብዝኾነ ሕጊ ከምዘይፍቀድ ጽቡቕ እምነት ከም ዘሎካ ዝገልጽ መግለጺ፡']

['(5) እቲ ኣብ ምልክታ ዘሎ ሓበሬታ ልክዕ ምዃኑን ነቲ ዝተጣሕሰ መሰል ናይ ምጥባቕ ስልጣን ከምዘለካን ብገበን ናይ ሓሶት ምስክርነት ዝተፈረመ መግለጺኻ፣']

["ከምኡ'ውን (6) ናይ ዋና መሰል ደራሲ ወይ ብስም ዋና መሰል ደራሲ ክሰርሕ ዝተፈቕደሉ ሰብ፡ ኣካላዊ ወይ ኤለክትሮኒካዊ ፊርማ። "]

['እዚ ኩሉ ኣብ ላዕሊ ዝተጠቕሰ ሓበሬታ ዘይምምላእ ነቲ ጥርዓንካ ናይ ምምላስ መስርሕ ክድንጉዮ ይኽእል እዩ።']

['ርክብ']

['ዝኾነ ሕቶ / ሓሳብ ምስ ዝህልወኩም ብኢሜይል ስደዱልና።']

How to treat prostate cancer?

There are several treatment options available for prostate cancer, depending on the stage and aggressiveness of the cancer, as well as the patient's overall health and personal preferences.

Some common treatments include:

1. Active surveillance: This approach involves closely monitoring the cancer with regular checkups and tests, rather than immediately starting treatment.

It may be suitable for men with low-risk prostate cancer.

2. Surgery: A prostatectomy is a surgical procedure to remove the prostate gland.

It can be done through open surgery or laparoscopically (using small incisions and specialized tools).

3. Radiation therapy: This treatment uses high-energy radiation to kill cancer cells.

It can be delivered externally (from a machine outside the body) or internally (through implants placed near the tumor).

4. Hormone therapy: This treatment reduces the levels of male hormones (androgens) in the body, which can slow or stop the growth of prostate cancer.

It can be used alone or in combination with other treatments.

5. Chemotherapy: This treatment uses drugs to kill cancer cells.

It may be used for advanced prostate cancer that has spread to other parts of the body.

6. Immunotherapy: This treatment helps the immune system fight cancer.

It may be used for advanced prostate cancer that has not responded to other treatments.

7. Targeted therapy: This treatment targets specific genes or proteins that help cancer cells grow and survive.

It may be used for advanced prostate cancer that has not responded to other treatments.

8. Cryotherapy: This treatment uses extreme cold to freeze and kill cancer cells.

It may be used for early-stage prostate cancer or for cancer that has come back after other treatments.

9. High-intensity focused ultrasound (HIFU): This treatment uses high-frequency sound waves to heat and destroy cancer cells.

It may be used for early-stage prostate cancer or for cancer that has come back after other treatments.

10. Watchful waiting: This approach involves closely monitoring the cancer with regular checkups and tests, but not starting treatment unless symptoms appear or change.

It may be suitable for older men with slow-growing prostate cancer and other serious health conditions.

It is important to discuss all treatment options with a healthcare team to determine the best course of action for each individual case.

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['ብዛዕባ']

['BioMedLib ሕቶን መልስን ንምፍጣር ኣውቶማቲክ ኮምፒዩተራት (ማሽን-ሊንጊንግ ኣልጎሪዝም) ይጥቀም።']

["ካብ 35 ሚልዮን ናይ ባዮሜዲካል ጽሑፋት ናይ PubMed/Medline ጀሚርና፡ ከምኡ'ውን ናይ RefinedWeb ዌብሳይታት።"]

['ኣብ "References" ከምኡውን "Disclaimer" ተመልከት።']