What are the risk factors for Alzheimer?

['Yingisela tluka leri']

Hi swihi swilo leswi nga endlaka leswaku munhu a khomiwa hi vuvabyi bya Alzheimer?

Ku ni swilo swo hlayanyana leswi nga endlaka leswaku munhu a khomiwa hi vuvabyi bya Alzheimer, ku katsa ni leswi landzelaka:

1.Malembe: Khombo ro khomiwa hi vuvabyi bya Alzheimer ri ya ri andza loko munhu a ya a dyuhala, naswona vanhu vo tala va khomiwa hi vuvabyi lebyi loko se va ri ni malembe ya 65.

2. Xitekela: Ku va ni ndyangu lowu nga ni vuvabyi bya Alzheimer kumbe ku va ni xitekela xo karhi xo tanihi APOE-e4 swi nga ha engetela khombo ro khomiwa hi vuvabyi lebyi.

3. Ku vaviseka ka nhloko: Ku va munhu a tshame a vaviseka nhloko kumbe a tshamela ku pfilunganyeka swi nga ha engetela khombo ra ku khomiwa hi vuvabyi bya Alzheimer.

4. Vuvabyi bya mbilu: Swiyimo leswi khumbaka mbilu ni misiha ya ngati, swo tanihi nsusumeto wa le henhla wa ngati, kholesteroli yo tala, vuvabyi bya chukele ni ku nyuhela ngopfu, swi nga ha engetela khombo ra vuvabyi bya Alzheimer.

5. Ndlela leyi munhu a hanyaka ha yona: Ku dzaha, ku nwa ngopfu byala ni ku nga endli vutiolori swi nga ha endla leswaku munhu a khomiwa hi vuvabyi bya Alzheimer.

6. Ku nga tirhi kahle emianakanyweni: Ku pfumala ku gingiriteka emianakanyweni ni ku nga dyondzekanga swi nga ha engetela khombo ro khomiwa hi vuvabyi bya Alzheimer.

7. Swiphiqo swa ku etlela: Swiphiqo swa ku etlela, swo tanihi ku heleriwa hi moya loko munhu a etlele, swi nga ha engetela khombo ra ku khomiwa hi vuvabyi bya Alzheimer.

8. Swivangelo swa mianakanyo: Ntshikilelo, ntshikilelo ni ku tihambanisa ni vanhu van'wana swi nga ha engetela khombo ra vuvabyi bya Alzheimer.

I swa nkoka ku xiya leswaku ku va ni xin'we kumbe swo tala swa swilo leswi swi nga vangaka vuvabyi lebyi a swi vuli swona leswaku munhu u ta khomiwa hi vuvabyi bya Alzheimer naswona vanhu van'wana lava nga riki na swona swilo leswi nga vangaka vuvabyi lebyi va nga ha khomiwa hi vuvabyi lebyi.

Hambiswiritano, ku twisisa swilo leswi nga vangaka vuvabyi lebyi swi nga pfuna vanhu leswaku va teka magoza yo byi hunguta ni ku antswisa rihanyo ra byongo.

['Tinhlamuselo']

PubMed/Medline https://www.nlm.nih.gov/databases/download/pubmed_medline.html

RefinedWeb https://arxiv.org/abs/2306.01116

Borenstein AR, Copenhaver CI, Mortimer JA: Early-life risk factors for Alzheimer disease. Alzheimer Dis Assoc Disord. , 20 (1): 63-72.

Pansari K, Gupta A, Thomas P: Alzheimer's disease and vascular factors: facts and theories. Int J Clin Pract. 2002, 56 (3): 197-203.

Kivipelto M, Helkala EL, Laakso MP, Hänninen T, Hallikainen M, Alhainen K, Iivonen S, Mannermaa A, Tuomilehto J, Nissinen A, Soininen H: Apolipoprotein E epsilon4 allele, elevated midlife total cholesterol level, and high midlife systolic blood pressure are independent risk factors for late-life Alzheimer disease. Ann Intern Med. 2002, 137 (3): 149-55.

Skoog I, Kalaria RN, Breteler MM: Vascular factors and Alzheimer disease. Alzheimer Dis Assoc Disord. , 13 Suppl 3 (): S106-14.

Bidzan L: [Initial symptoms and risk factors in Alzheimer's dementia]. Psychiatr Pol. , 28 (2): 207-19.

Gorelick PB: Risk factors for vascular dementia and Alzheimer disease. Stroke. 2004, 35 (11 Suppl 1): 2620-2.

Kummer BR, Diaz I, Wu X, Aaroe AE, Chen ML, Iadecola C, Kamel H, Navi BB: Associations between cerebrovascular risk factors and parkinson disease. Ann Neurol. 2019, 86 (4): 572-581.

Luchsinger JA, Reitz C, Honig LS, Tang MX, Shea S, Mayeux R: Aggregation of vascular risk factors and risk of incident Alzheimer disease. Neurology. 2005, 65 (4): 545-51.

['Xihlambanyo xa vutihlamuleri: swa vutshunguri']

['Website leyi yi endleriwe ku dyondzisa ni ku nyika rungula ntsena naswona a yi nyiki switsundzuxo swa vutshunguri kumbe mintirho ya vativi va swa vutshunguri.']

['Rungula leri nyikeriweke a ri fanelanga ri tirhisiwa ku kambela kumbe ku tshungula xiphiqo xa rihanyo kumbe vuvabyi, naswona lava lavaka xitsundzuxo xa vutshunguri va fanele va vonana ni dokodela la nga ni mpfumelelo.']

['Xiya leswaku ndlela leyi ti-neural net ti hlamulaka swivutiso ha yona a yi pakanisi ngopfu loko ku vulavuriwa hi tinomboro, to tanihi nhlayo ya vanhu lava khomiweke hi vuvabyi byo karhi.']

["Minkarhi hinkwayo kombela xitsundzuxo eka dokodela wa wena kumbe eka muongori la fanelekaka malunghana ni xiyimo xa rihanyo ra wena. U nga tshuki u honisa xitsundzuxo xa dokodela kumbe u hlwela ku xi lava hikwalaho ka leswi u swi hlayeke eka website leyi. Loko u ehleketa leswaku u le xiyin'weni xa xihatla xa rihanyo, bela riqingho eka 911 kumbe u ya ekamareni ra xihatla leri nga ekusuhi na wena hi ku hatlisa. A ku na vuxaka bya dokodela ni muvabyi lebyi tumbuluxiweke hi website leyi kumbe ku tirhisiwa ka yona. BioMedLib kumbe vatirhi va yona, kumbe un'wana ni un'wana la hoxaka xandla eka website leyi, a nga endli switiyisekiso, leswi nga erivaleni kumbe leswi nga erivaleni, malunghana ni rungula leri nga laha kumbe ku tirhisiwa ka rona."]

['Ku ala ku byarha vutihlamuleri: mfanelo yo tsala']

['Nawu wa Digital Millennium Copyright Act wa 1998, 17 U.S.C. § 512 (DMCA) wu nyika tindlela ta ku tihlanganisa na vini va timfanelo ta vuhleri lava va tshembaka leswaku swilo leswi humelelaka eka Internet swi tlula timfanelo ta vona ehansi ka nawu wa vuhleri wa U.S.']

['Loko u tshemba leswaku rungula kumbe swilo leswi kumekaka eka website ya hina kumbe eka mintirho ya hina swi tlula mfanelo ya wena yo endla swilo, wena (kumbe muyimeri wa wena) u nga hi rhumela xitiviso u kombela leswaku rungula kumbe swilo leswi swi susiwa kumbe swi siveriwa.']

['Switiviso swi fanele ku rhumeriwa hi ku tsala hi imeyili (languta eka xiyenge xa "Vuxaka" eka adirese ya imeyili).']

["DMCA yi lava leswaku xitiviso xa wena xa ku tlula nawu wa mfanelo ya ku tsala xi katsa mahungu lawa landzelaka: (1) nhlamuselo ya ntirho lowu nga na mfanelo ya ku tsala lowu ku vuriwaka leswaku wu tluriwile; (2) nhlamuselo ya leswi ku vuriwaka leswaku swi tlula nawu wa ku tsala ni mahungu lama ringaneke ku hi pfumelela ku kuma leswi nga endzeni; (3) mahungu ya ku tihlanganisa na wena, ku katsa ni adirese ya wena, nomboro ya riqingho na adirese ya imeyili; (4) xitiviso xa wena xa leswaku u ni ripfumelo ra leswaku leswi nga endzeni hi ndlela leyi ku vilelaka ha yona a swi pfumeleriwanga hi n'wini wa mfanelo ya ku tsala, kumbe muyimeri wa yena, kumbe hi ku tirha ka nawu wihi na wihi; "]

['(5) xitiyisiso xa wena, lexi sayiniweke ehansi ka nxupulo wa ku hemba, xa leswaku mahungu lama nga eka xitiviso i ntiyiso ni leswaku u na matimba yo tirhisa timfanelo ta vuqambi leti ku vuriwaka leswaku ti tluriwile;']

["na (6) ku sayina ka xiviri kumbe ka elektroniki ka n'wini wa mfanelo ya vuqambi kumbe munhu la pfumeleriweke ku endla hi vito ra n'wini wa mfanelo ya vuqambi. "]

['Loko u nga nghenisi vuxokoxoko hinkwabyo lebyi nga laha henhla swi nga endla leswaku ku tirhana ni xivilelo xa wena swi hlwela.']

['Ku Tihlanganisa']

['Hi kombela u hi rhumela imeyili hi xivutiso/xiringanyeto xihi na xihi.']

What are the risk factors for alzheimer?

There are several risk factors for Alzheimer's disease, including:

1. Age: The risk of developing Alzheimer's disease increases with age, with most people being diagnosed after the age of 65.

2. Genetics: Having a family history of Alzheimer's disease or carrying certain genes, such as the APOE-e4 gene, can increase the risk of developing the disease.

3. Head injury: A history of severe head trauma or multiple concussions may increase the risk of Alzheimer's disease.

4. Cardiovascular health: Conditions that affect the heart and blood vessels, such as high blood pressure, high cholesterol, diabetes, and obesity, may increase the risk of Alzheimer's disease.

5. Lifestyle factors: Smoking, excessive alcohol consumption, and lack of physical exercise may increase the risk of Alzheimer's disease.

6. Cognitive inactivity: A lack of mental stimulation and low levels of education may increase the risk of Alzheimer's disease.

7. Sleep disorders: Sleep disorders, such as sleep apnea, may increase the risk of Alzheimer's disease.

8. Psychological factors: Depression, stress, and social isolation may increase the risk of Alzheimer's disease.

It is important to note that having one or more of these risk factors does not necessarily mean that a person will develop Alzheimer's disease, and some people with no known risk factors may still develop the disease.

However, understanding these risk factors can help individuals take steps to reduce their risk and promote brain health.

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