What is pathophysiology of Anxiety?

['ⵙⵎⴷ ⵜⴰⵖⴹⴼⵜ ⴰⴷ']

ⵎⴰⴷ ⵉⴳⴰⵏ ⵜⴰⴼⵉⵣⵉⴽⵓⵍⵓⵊⵉⵜ ⵜⴰⴱⴰⵜⵓⵀⵓⵍⵓⵊⵉⵜ ⵏ ⵜⴽⵏⵏⴹⵜ?

ⴷⴰ ⵉⵜⵜⴰⵡⵙ ⵓⴼⵉⵣⵉⵢⵓⵍⵓⵊⵉ ⴰⴱⴰⵜⵓ ⵏ ⵜⴽⵏⵏⴹⵜ ⴳ ⵜⵖⵓⵔⵉ ⵏ ⵉⵎⵉⴽⴰⵏⵉⵣⵎⵏ ⵉⴱⵢⵓⵍⵓⵊⵉⵏ ⴷ ⵉⴽⵏⵏⴹⴰⵏⵏ ⵏⵏⴰ ⵉⵍⵍⴰⵏ ⴷⴷⴰⵡ ⵓⴼⵓⵙ ⵏ ⵜⵙⵙⴰⵙⵉⵏ ⵏ ⵜⴽⵏⵏⴹⵜ.

ⴷⴰ ⵉⵜⵜⴰⵎⵓ ⴳ ⵓⵔⵎⴰⵙ ⵏ ⵉⵙⵏⴼⴰⵍ ⴳ ⵓⵏⵍⵍⵉ ⴷ ⵜⴼⴳⴳⴰ ⵏⵏⴰ ⵉⵜⵜⴰⵡⵙⵏ ⴳ ⵓⵙⴱⵓⵖⵍⵓ ⴷ ⵓⵙⵎⴽⵍ ⵏ ⵜⵎⵉⵜⴰⵔ ⵏ ⵜⴽⵏⵏⴹⵜ.

ⵉⵍⵍⴰ ⴳ ⵓⵢⴰ ⵓⵣⵣⵔⴰⵢ ⵏ ⵜⵉⵍⴰⵍⵜ ⵏ ⵜⵙⵏⵎⴰⵍⴰⵢⵉⵏ ⵜⵉⵎⴰⵙⵙⴰⵏⵉⵏ ⵏ ⵜⴰⵖⵢⴰⵢⵜ, ⵉⵀⵓⵔⵎⵓⵏⵏ, ⴷ ⵜⵓⵚⴽⵉⵡⵉⵏ ⵏ ⵓⵏⵍⵍⵉ ⴳ ⵓⵙⵏⵎⴰⵍⴰ ⵏ ⵜⵎⵔⴰⵔⵓⵜⵉⵏ ⵏ ⵜⵓⵔⴷⴰ ⴷ ⵜⴽⵏⵏⴹⵜ.

ⴰⵔ ⵉⵜⵜⴰⵣⵣⴰⵍ ⵓⵔⵣⵣⵓ ⴳ ⵢⵉⴳⵔ ⴰⴷ ⵅⴼ ⵓⵙⵙⴰⵏ ⵏ ⵜⵎⵏⵜⵉⵍⵉⵏ ⵜⵉⴷⵙⵍⴰⵏⵉⵏ ⵏ ⵜⵎⴰⴹⵓⵏⵉⵏ ⵏ ⵜⴽⵏⵏⴹⵜ ⴷ ⵓⵙⴱⵓⵖⵍⵓ ⵏ ⵜⵙⵏⵉⵊⵊⵉⵜⵉⵏ ⵉⵕⵡⴰⵏ.

['ⵉⵙⵓⴳⴰⵎ']

PubMed/Medline https://www.nlm.nih.gov/databases/download/pubmed_medline.html

RefinedWeb https://arxiv.org/abs/2306.01116

Milad MR, Rauch SL: The role of the orbitofrontal cortex in anxiety disorders. Ann N Y Acad Sci. 2007, 1121 (): 546-61.

Pine DS: Pathophysiology of childhood anxiety disorders. Biol Psychiatry. 1999, 46 (11): 1555-66.

Shefer S, Gordon C, Avraham KB, Mintz M: Balance deficit enhances anxiety and balance training decreases anxiety in vestibular mutant mice. Behav Brain Res. 2015, 276 (): 76-83.

Brotman MA, Rich BA, Schmajuk M, Reising M, Monk CS, Dickstein DP, Mogg K, Bradley BP, Pine DS, Leibenluft E: Attention bias to threat faces in children with bipolar disorder and comorbid lifetime anxiety disorders. Biol Psychiatry. 2007, 61 (6): 819-21.

Boyer P: Do anxiety and depression have a common pathophysiological mechanism? Acta Psychiatr Scand Suppl. 2000, (406): 24-9.

Du J, Szabo ST, Gray NA, Manji HK: Focus on CaMKII: a molecular switch in the pathophysiology and treatment of mood and anxiety disorders. Int J Neuropsychopharmacol. 2004, 7 (3): 243-8.

['ⴰⵙⴱⴷⵉⴷ: ⴰⵎⵙⵏⵉⵊⵊⵉ']

['ⴰⵙⵉⵜ ⴰⴷ, ⴷⴰ ⵉⵜⵜⵓⴼⴽⴰ ⵖⴰⵙ ⵉ ⵜⵖⴰⵡⵙⵉⵡⵉⵏ ⵏ ⵓⵙⴳⵎⵉ ⴷ ⵉⵏⵖⵎⵉⵙⵏ, ⵓⵔ ⵉⴳⵉ ⴰⵖⴰⵡⴰⵙ ⵏ ⵜⵉⴽⴽⵉ ⵏ ⵜⵉⵏⵓⵔⵣⵉⵜⵉⵏ ⵜⵉⴷⵓⵙⴰⵏⵉⵏ ⵏⵖⴷ ⵜⵉⵡⵓⵔⵉⵡⵉⵏ ⵜⵉⵣⵣⵓⵍⴰⵏⵉⵏ.']

['ⵓⵔ ⵉⵅⵚⵚⴰ ⴰⴷ ⵜⵜⵓⵙⵎⵔⵙ ⵉⵏⵖⵎⵉⵙⵏ ⵉⵜⵜⵓⴼⴽⴰⵏ ⴳ ⵓⵙⵎⵔⵙ ⵏ ⵓⵙⵎⵉⴳⵍ ⵏⵉⵖ ⵉⵊⵉⵊⵊⵉ ⵏ ⵉⵎⵓⴽⵔⵉⵙⵏ ⵏ ⵜⴷⵓⵙⵉ ⵏⵖⴷ ⵜⵎⴰⴹⵓⵏⵉⵏ, ⴷ ⵡⵉⵏⵏⴰ ⵉⵔⴰⵏ ⴰⵙⵖⵏⵓ ⴰⵎⵙⵏⵉⵊⵊⵉ ⴰⵡⵏ ⵉⵜⵜⵓⴼⴽⴰⵏ ⵉⵇⵇⴰⵏ ⴰⴷ ⵉⵙⴰⵡⵍ ⴷ ⵢⴰⵏ ⵓⵎⵙⵏⵉⵊⵊⵉ ⵉⵜⵜⵓⵊⵊⴰⵏ.']

['ⵙⵙⴽⵜⵉ ⴳ ⵜⴱⵔⴰⵜ ⵎⴰⵙ ⵜⵣⵟⵟⴰ ⵏ ⵜⵎⴰⵖⵓⵏⵜ ⵏⵏⴰ ⵉⵜⵜⴰⵔⴰⵏ ⵜⵉⵎⵔⴰⵔⵓⵜⵉⵏ ⵉ ⵉⵙⵇⵙⵉⵜⵏ, ⵓⵔ ⵜⴽⴽⵉ ⵜⵖⴰⵔⴰ ⴽⵉⴳⴰⵏ ⴳ ⵎⴰⴷ ⵉⵥⵍⵉⵏ ⵙ ⵜⵓⵎⴰⵢⵜ ⵏ ⵓⵟⵟⵓⵏ. ⵙ ⵓⵎⴷⵢⴰ, ⵓⵟⵟⵓⵏ ⵏ ⵎⴷⴷⵏ ⵉⵜⵜⵓⵙⵏⴼⴰⵍⵏ ⵉ ⵜⵎⴰⴹⵓⵏⵜ ⵉⵥⵍⵉⵏ.']

['ⴰⵀⴰ ⵣⵣⵔⵉⵢ ⵉ ⵓⵎⵙⴰⵙⴰ ⵏ ⵓⴷⵓⴽⵜⵓⵕ ⵏⵏⴽ ⵏⵖⴷ ⴽⵔⴰ ⵏ ⵓⵎⵙⵙⵉⵡⵍ ⵏ ⵜⴷⵓⵙⵉ ⵢⴰⴹⵏ ⵉⵖⵉⵢⵏ ⴳ ⵎⴰⴷ ⵉⵥⵍⵉⵏ ⵙ ⵓⴷⴷⴰⴷ ⵏ ⵜⴷⵓⵙⵉ ⵏⵏⴽ. ⵓⵔ ⴰⴽⴽⵡ ⵜⵃⵍⴰⵎ ⴰⵖ ⴰⵖⴰⵎⵓⵙ ⵏ ⵓⴷⵓⵙⵉ ⵏⵖⴷ ⵜⵉⵖⵣⵉ ⴳ ⵓⵙⵣⵣⵔⵉⵢ ⵏⵏⵙ ⴰⵛⴽⵓ ⵏⵜⵜⴰⵜ ⵜⵖⵔⵉⴷ ⴳ ⵓⵙⵉⵜ ⴰⴷ. ⵎⴽ ⵜⵓⵔⴷⴰ ⵎⴰⵙ ⴷⴰⵔⴽ ⴰⴷ ⵢⵉⵍⵉ ⵢⴰⵏ ⵓⴷⴷⴰⴷ ⵏ ⵜⴷⵓⵙⵉ ⵉⵣⵉⵍⵏ, ⵙⴰⵡⵍⴰⵜ ⵙ 911 ⵏⵖⴷ ⴷⴷⵓ ⵙ ⵓⵙⵉⵔⴰ ⵏ ⵓⵣⵣⵔⴰⵢ ⵏ ⵣⵉⴽⴽ. ⵓⵔ ⴷⴰ ⵉⵜⵜⵓⵙⴽⴰⵔ ⴽⵔⴰ ⵏ ⵓⵣⴷⴰⵢ ⵏ ⵓⵎⵙⴳⵏⴰⴼ ⴷ ⵓⵎⵏⵉⴳ ⵙ ⵓⵙⵉⵜ ⴰⴷ ⵏⵖⴷ ⴰⵙⵎⵔⵙ ⵏⵏⵙ. ⵓⵔ ⴷⴰ ⵜⵙⴽⴰⵔ ⴱⵢⵓⵎⵉⴷⵍⴱ ⵏⵖⴷ ⵉⵎⵙⵡⵓⵔⵉⵏ ⵏⵏⵙ ⵏⵖⴷ ⴽⵔⴰ ⵏ ⵓⵎⴷⵔⴰⵡ ⴳ ⵓⵙⵉⵜ ⴰⴷ ⴽⵔⴰ ⵏ ⵓⵙⵎⵏⵉⴷ, ⵙ ⵡⴰⵡⴰⵍ ⵏⵖⴷ ⵙ ⵓⵙⵓⵎⵔ, ⴳ ⵎⴰⴷ ⵉⵥⵍⵉⵏ ⵙ ⵉⵏⵖⵎⵉⵙⵏ ⵉⵜⵜⵓⴼⴽⴰⵏ ⴳ ⵓⵙⵉⵜ ⴰⴷ ⵏⵖⴷ ⵓⵙⵎⵔⵙ ⵏⵏⵙ.']

['ⵉⵣⵍⵉ: ⵉⵣⵔⴼⴰⵏ ⵏ ⵜⵉⵔⵔⴰ']

['ⵉⵍⵍⴰ ⴳ ⵓⵙⵍⴳⵏ ⵏ ⵓⵣⵔⴼ ⴰⵎⵓⵟⵟⵓⵏ ⵏ ⵓⵙⵏⴼⵍ ⵏ ⵜⵏⵖⵎⴰⵙⵜ ⵏ ⵓⵙⴳⴳⵡⴰⵙ ⵏ 1998, 17 U.S.C. § 512 (DMCA) ⵜⴰⵙⵏⵜⴰⵢⵜ ⵉ ⵉⵎⵥⵢⴰⵏⵏ ⵏ ⵉⵣⵔⴼⴰⵏ ⵏ ⵜⵏⵖⵎⴰⵙⵜ ⵏⵏⴰ ⵙⵙⵉⵜⵉⵎⵏ ⵉⵙ ⵉⵏⵖⵎⵉⵙⵏ ⵏⵏⴰ ⴷ ⵉⵜⵜⴼⴼⵖⵏ ⴳ ⵡⴰⵏⵜⵉⵔⵏⵉⵜ ⴷⴰ ⵜⵜⴳⴳⴰⵏ ⵉⵣⵔⴼⴰⵏ ⵏⵏⵙⵏ ⴷⴷⴰⵡ ⵓⵣⵔⴼ ⴰⵎⵓⵟⵟⵓⵏ ⴰⵎⵉⵔⵉⴽⴰⵏⵉ. ']

['ⵎⴽ ⵜⵍⵍⵉⴷ ⵙ ⵜⵖⴰⵍⵜ ⵉⵖⵓⴷⴰⵏ ⵎⴰⵙⴷ ⴽⵔⴰ ⵏ ⵜⵓⵎⴰⵢⵜ ⵏⵖⴷ ⴽⵔⴰ ⵏ ⵓⵙⵏⴼⴰⵔ ⵉⵜⵜⵓⴼⴽⴰⵏ ⴳ ⵓⵙⴷⴰⵡ ⵏⵏⵓⵏ ⵏⵖⴷ ⵜⵉⵙⵏⵙⵉ ⵏⵏⵓⵏ ⴷⴰ ⵉⵙⵙⴽⴰⵔ ⵜⵉⵕⵥⵉ ⵏ ⵓⵣⵔⴼ ⵏⵏⵓⵏ ⵏ ⵜⵉⵔⵔⴰ, ⵉⵖⵢ ⴰⴷ ⵜⴰⴷ ⴼⵍⵍⴰⵙ ⵏⵙⵔⵖⴷ (ⵏⵖⴷ ⴰⵎⴷⵢⴰⵣ ⵏⵏⴽ) ⵢⴰⵏ ⵓⵙⵏⵖⵎⵙ ⵏ ⵓⵙⵓⵜⵔ ⵏ ⵓⵙⵏⴼⴰⵔ ⵏ ⵜⵓⵎⴰⵢⵜ ⵏⵖⴷ ⴰⵙⵏⴼⴰⵔ ⴰⴷ ⵏⵖⴷ ⴰⵙⴱⴷⴷⵉ ⵏ ⵓⵣⵔⴼ ⵏ ⵓⴽⵛⵛⵓⵎ ⵖⵔⵙⵏ. ']

['ⵉⵇⵇⴰⵏ ⴰⴷ ⵜⵜⵢⵓⵔⴰⵢ ⵜⴱⵔⴰⵜ ⴰⴷ ⵙ ⵜⵖⴰⵔⴰⵙⵜ ⵏ ⵜⵉⵔⵔⴰ ⵙ ⵜⴱⵔⴰⵜ ⵜⵉⵍⵉⴽⵜⵕⵓⵏⵉⵜ (ⵥⵕ ⴰⵙⴷⴰⵡ ⵏ ⵜⴱⵔⴰⵜ ⵜⵉⵍⵉⴽⵜⵕⵓⵏⵉⵜ ⴳ ⵓⵎⵏⵏⵉ "ⵉⵎⵢⴰⵡⴰⴹⵏ").']

['ⴷⴰ ⵉⵜⵜⴻⵖⵜⴰⵙ ⵓⵙⵍⴳⵏ ⵏ ⵓⵎⵏⵖⵉ ⵅⴼ ⵉⵣⵔⴼⴰⵏ ⵏ ⵓⵎⴳⴰⵢ ⵉⵙ ⴷ ⵉⵇⵇⴰⵏ ⴰⴷ ⴳⵉⵙ ⵉⵍⵉⵏ ⵉⵏⵖⵎⵉⵙⵏ ⴰⴷ: (1) ⴰⵙⵏⵓⵎⵍ ⵏ ⵜⵡⵓⵔⵉ ⵉⵍⴰⵏ ⵉⵣⵔⴼⴰⵏ ⵏ ⵓⵎⴳⴰⵢ ⵏⵏⴰ ⵉⴳⴰⵏ ⴰⵙⵏⵜⵍ ⵏ ⵓⵣⵔⴼ ⵏ ⵓⵎⴳⴰⵢ; (2) ⴰⵙⵏⵓⵎⵍ ⵏ ⵜⵓⵎⴰⵢⵜ ⵏⵏⴰ ⵉⴳⴰⵏ ⴰⵙⵏⵓⵎⵍ ⵏ ⵉⵣⵔⴼⴰⵏ ⴷ ⵉⵏⵖⵎⵉⵙⵏ ⵏⵏⴰ ⵢⵓⵙⴰⵏ ⵃⵎⴰ ⴰⴷ ⵜ ⵏⴰⴼ; (3) ⵉⵏⵖⵎⵉⵙⵏ ⵏ ⵓⵎⵢⴰⵡⴰⴹ ⴰⴽⴷⴽ, ⴳ ⵉⵍⵍⴰ ⵓⵙⵖⵉⵎ ⵏⵏⴽ ⴷ ⵓⵟⵟⵓⵏ ⵏ ⵜⵉⵍⵉⴼⵓⵏ ⴷ ⵓⴷⵖⴰⵔ ⵏ ⵍⵢⵉⴱⵍ; (4) ⴰⵙⵉⵡⴹ ⵏⵏⴽ ⵏ ⵓⵙⵏⵓⵎⵍ ⵉⵖⵓⴷⴰⵏ ⵏⵏⴰ ⴳ ⵜⵍⵍⴰ ⵜⵣⵎⵎⴰⵔ ⵏ ⵓⵙⵏⵓⵎⵍ ⵏ ⵓⵙⵏⴼⵍ ⵏⵏⴰ ⵙ ⵉⵜⵜⵓⵙⵎⴳⴰⵍ ⵓⵔ ⵜ ⵢⵓⵊⵊⵉ ⵓⵎⵏⴳⴰⵢ ⵏ ⵉⵣⵔⴼⴰⵏ ⵏ ⵓⵎⴳⴰⵢ, ⵏⵖⴷ ⵓⵎⴷⵢⴰⵣ ⵏⵏⵙ, ⵏⵖⴷ ⵙ ⵓⴹⴼⴰⵕ ⵏ ⴽⵔⴰ ⵏ ⵓⵙⵍⴳⵏ; ']

['5. ⵢⴰⵏ ⵓⵙⵉⵡⴹ ⵏⵏⴽ, ⵉⵜⵜⵓⵙⴳⵎⴰⴹⵏ ⴷⴷⵓ ⵏ ⵓⵃⵟⵟⵓ ⵏ ⵜⵔⴳⴰⵍⵜ, ⵎⴰⵙ ⵉⵏⵖⵎⵉⵙⵏ ⵉⵍⵍⴰⵏ ⴳ ⵓⵏⵖⵎⵉⵙ ⴰⴷ ⴳⴰⵏ ⵉⵙⴷⴰⵡⵏ ⴷ ⵎⴰⵙ ⵖⵓⵔⴽ ⵜⵓⵔⴰⴳⵜ ⴰⴼⴰⴷ ⴰⴷ ⵜⵙⵎⴷⵔⴼ ⵜⵉⵡⵏⴳⵉⵎⵉⵏ ⵉⵜⵜⵉⵏⵉ ⵉⵙ ⵜⵜⵓⵙⵏⴼⴰⵍⵏ;']

['ⴷ (6) ⵢⴰⵏ ⵓⵣⵎⵎⴻⵎ ⴰⴽⵎⴰⵎ ⵏⵖⴷ ⴰⵍⵉⴽⵜⵔⵓⵏⵉ ⵏ ⵉⵎⵥⵍⵉ ⵏ ⵓⵣⵔⴼ ⵏ ⵜⵉⵔⵔⴰ ⵏⵖⴷ ⵢⴰⵏ ⵓⴼⴳⴰⵏ ⵉⵜⵜⵓⵙⵎⴰⴳⵍⵏ ⵙ ⵜⵡⵓⵔⵉ ⴳ ⵜⵙⴳⴰ ⵏ ⵉⵎⵥⵍⵉ ⵏ ⵓⵣⵔⴼ ⵏ ⵜⵉⵔⵔⴰ. ']

['ⵎⴽ ⵓⵔ ⵜⵙⵎⵓⵜⵜⵉⴷ ⴽⵓⵍⵍⵓ ⵉⵏⵖⵎⵉⵙⵏ ⴰⴼⵍⵍⴰ, ⵉⵥⴹⴰⵕ ⴰⴷ ⵉⵙⵙⵉⵍⵉ ⵓⵙⵙⵉⵖⵣⵉⵏ ⵏ ⵓⵙⵎⴽⵍ ⵏ ⵡⴰⵙⵉⴼ ⵏⵏⴽ.']

['ⴰⵎⵢⴰⵡⴰⴹ']

['ⵙⵇⵙⴰⵖ ⴷⵉⵖ ⴰⴷ ⵜⵙⵏⵖⵎⵙⴷ ⴽⵔⴰ ⵏ ⵓⵙⵇⵙⵉ/ ⵜⴰⵏⵏⴰⵢⵜ.']

What is pathophysiology of anxiety?

Pathophysiology of anxiety refers to the study of the physiological and biological mechanisms underlying anxiety disorders.

It involves understanding the changes in the brain and body that contribute to the development and maintenance of anxiety symptoms.

This includes examining the role of neurotransmitters, hormones, and brain structures in the regulation of fear and anxiety responses.

Research in this area aims to identify the underlying causes of anxiety disorders and develop more effective treatments.

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['ⵖⴼ']

['ⴷⴰ ⵉⵙⵙⵎⵔⴰⵙ ⴱⵢⵓⵎⵉⴷⵍⴱ ⵉⵎⴰⵙⵙⵏ ⵏ ⵓⵙⵖⵉⵡⵙ ⵉⵙⵎⵎⴰⵏⵏ (ⴰⵍⴳⵓⵔⵉⵜⵎ ⵏ ⵓⵍⵎⵎⵓⴷ ⵏ ⵉⵎⵉⵙⵏ) ⵉ ⵓⵙⵓⴼⵖ ⵏ ⵉⴽⵔⵡⴰⵏ ⵏ ⵉⵙⵇⵙⵉⵜⵏ ⴷ ⵜⵎⵔⴰⵔⵓⵜⵉⵏ.']

['ⴷⴰ ⵏⵙⵙⵏⵜⵉ ⵙ 35 ⵎⵍⵢⵓⵏ ⵏ ⵜⵥⵕⵉⴳⵉⵏ ⵜⵉⵎⵙⵏⵉⵊⵊⵉⵏ ⵏ ⵜⵓⴷⵔⵜ ⵏ ⴱⵓⴱⵎⵉⴷ/ⵎⵉⴷⵍⵉⵏ. ⴰⵡⴷ ⵜⵉⴼⵔⵜ ⵏ ⵡⵉⴱ ⵏ ⵔⵉⴼⵉⵏⴷⵡⵉⴱ.']

['ⵥⵕ "ⵜⵓⵎⴰⵔ" ⴰⵡⴷ "ⴰⵙⵎⵉⴳⵍ".']