El morbo de Alzheimer xe un disturbo neurodegenerativo progresivo che colpisse principalmente el zervel, causando perdita de memoria, declino cognitivo e cambiamenti de conportamento.
Ła causa esata del morbo de Alzheimer no ła xe pienamente capìa, ma se crede che ła sia el risultato de na conbinasion de fatori genetici, ambientałi e stiłe de vita.
Alcuni dei fatori che pol contribuir al sviłupo del morbo de Alzheimer xe:
1. Genetica: Xe stai identificà serti geni che aumenta el riscio de sviluppàr el morbo de Alzheimer, in particołare el gene apolipoproteina E (APOE).
2. Età: El ris-cio de ciapar el morbo de Alzheimer aumenta co l'età, e ała major parte dełe persone vien diagnosticà dopo i 65 anni.
3. Storia faméja: aver na storia faméja de małatia de Alzheimer pol aumentar el riscio de sviłupar ła condision.
4. Lesioni ała testa: 'na storia de lesioni ała testa, in particołar quełe che porta ała perdita de cosiensa, pol aumentar el riscio de Alzheimer.
5. Fatori de riscio cardiovascołari: Condision come alta presion sanguigna, colesterolo alto e diabete pol aumentar el riscio de sviluppàr el morbo de Alzheimer.
6. Fattori del stiłe de vita: un stiłe de vita sedentario, na dieta scarsa e a mancansa de stimolo mentale pol aumentar el riscio del morbo de Alzheimer.
7. Inflamasion: L'infiamasion cronica nel zervello pol contribuir al sviłupo del morbo de Alzheimer.
8. Stress ossidativo: Un squilibrio tra a produsion de radicałi liberi e a capacità del corpo de disintossicarli pol contribuir al sviłupo del morbo de Alzheimer.
9. Plache amiloidi e grovigli neurofibrillari: L'acumułamento de plache amiloidi e grovigli neurofibrillari nel zervello xe un segno distintivo del morbo de Alzheimer, ma el so ruoło nel sviłupo deła condision no xe pienamente capìo.
Xe inportante notare che ła causa del morbo de Alzheimer xe conplesa e probabilmente coinvolge na combinasion de sti fatori.
Łe ricerche xe in corso pa capir mejo i mecanismi fondamentałi e sviłupar cure efficaci pa sta condision devastante.
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Mahami-Oskouei M, Hamidi F, Talebi M, Farhoudi M, Taheraghdam AA, Kazemi T, Sadeghi-Bazargani H, Fallah E: Toxoplasmosis and Alzheimer: can Toxoplasma gondii really be introduced as a risk factor in etiology of Alzheimer? Parasitol Res. 2016, 115 (8): 3169-74.
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What causes alzheimer?
Alzheimer's disease is a progressive neurodegenerative disorder that primarily affects the brain, causing memory loss, cognitive decline, and behavioral changes.
The exact cause of Alzheimer's disease is not fully understood, but it is believed to result from a combination of genetic, environmental, and lifestyle factors.
Some of the factors that may contribute to the development of Alzheimer's disease include:
1. Genetics: Certain genes have been identified that increase the risk of developing Alzheimer's disease, particularly the apolipoprotein E (APOE) gene.
2. Age: The risk of developing Alzheimer's disease increases with age, with most people being diagnosed after the age of 65.
3. Family history: Having a family history of Alzheimer's disease may increase the risk of developing the condition.
4. Head injuries: A history of head injuries, particularly those that result in loss of consciousness, may increase the risk of Alzheimer's disease.
5. Cardiovascular risk factors: Conditions such as high blood pressure, high cholesterol, and diabetes may increase the risk of developing Alzheimer's disease.
6. Lifestyle factors: A sedentary lifestyle, poor diet, and lack of mental stimulation may increase the risk of Alzheimer's disease.
7. Inflammation: Chronic inflammation in the brain may contribute to the development of Alzheimer's disease.
8. Oxidative stress: An imbalance between the production of free radicals and the body's ability to detoxify them may contribute to the development of Alzheimer's disease.
9. Amyloid plaques and neurofibrillary tangles: The accumulation of amyloid plaques and neurofibrillary tangles in the brain is a hallmark of Alzheimer's disease, but the role they play in the development of the condition is not fully understood.
It is important to note that the cause of Alzheimer's disease is complex and likely involves a combination of these factors.
Research is ongoing to better understand the underlying mechanisms and develop effective treatments for this devastating condition.
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