乳腺癌的病理生理學指的是乳腺癌發展和進展過程中,
癌細胞在乳腺組織中不受控制的生長及擴散.
乳腺癌的發病率與發展速度都與其他疾病有關,
乳腺癌的一些關鍵的病理生理變化包括:
乳腺癌患者的風險可增加.
這些突變可以是遺傳或是人一生中獲得的.
激素, 尤其是雌激素, 可能會對乳腺癌的發展和增長起到一定的作用.
激素水平不平衡或暴露於過多雌激素可能增加患乳腺癌的風險.
乳腺組織的慢性炎症可能會促使癌細胞的生長和存活,
癌症的微環境:包括細胞外基質,免疫細胞和血管在內,
乳腺癌可透過淋巴系統或血液擴散至身體其他部位,
了解乳腺癌的病理生理學對於開發有效的預防,早期發現及治療策略至關重要.
PubMed/Medline https://www.nlm.nih.gov/databases/download/pubmed_medline.html
RefinedWeb https://arxiv.org/abs/2306.01116
Underwood SM: Breast cancer in African American women: nursing essentials. ABNF J. , 17 (1): 3-14.
Paliwal SR, Paliwal R, Agrawal GP, Vyas SP: Liposomal nanomedicine for breast cancer therapy. Nanomedicine (Lond). 2011, 6 (6): 1085-100.
Rauch GM, Adrada BE: Comparison of Breast MR Imaging with Molecular Breast Imaging in Breast Cancer Screening, Diagnosis, Staging, and Treatment Response Evaluation. Magn Reson Imaging Clin N Am. 2018, 26 (2): 273-280.
Wei H, Wang H, Ji Q, Sun J, Tao L, Zhou X: NRBP1 is downregulated in breast cancer and NRBP1 overexpression inhibits cancer cell proliferation through Wnt/β-catenin signaling pathway. Onco Targets Ther. 2015, 8 (): 3721-30.
Eden JA: Human breast cancer stem cells and sex hormones--a narrative review. Menopause. 2010, 17 (4): 801-10.
Schneider BP, Winer EP, Foulkes WD, Garber J, Perou CM, Richardson A, Sledge GW, Carey LA: Triple-negative breast cancer: risk factors to potential targets. Clin Cancer Res. 2008, 14 (24): 8010-8.
['提供醫療建議或專業服務.']
['提供給我們的資訊不應用於診斷或治療健康問題或疾病,']
['特別是數字內容不準確, 例如確診患有特定疾病的人數.']
['請隨時向您的醫生或其他合格的醫療人員諮詢您的病情. 請勿因為您在本網站上閱讀的內容而忽視專業醫療建議或延遲尋求. 如果您認為您可能有醫療緊急情況,請立即致電911或前往最近的急診室. 本網站或其使用並未建立醫師-病人關係. BioMedLib及其員工或本網站的任何貢獻者,都不會就此提供的信息或其使用作出任何明示或暗示的聲明.']
['該法案為那些認為網路上出現的內容侵犯了他們在美國版權法下的權利的版權所有者提供了補救. ']
['您 (或您的代理人) 可向我們發送通知, 要求移除內容或資料,或封鎖存取.']
['請見"聯絡方式"一節.']
['要求您的侵權聲明包含以下資訊: (1) 侵權聲明所涉及的著作的描述; (2) 侵權聲明所涉及的內容的描述及足以讓我們找到內容的資訊; (3) 您的聯絡方式,']
['(5) 您在作假宣誓的懲罰下簽署的聲明, 表示通知中的資訊是正確的,']
['且 (6) 版權所有者或授權代表其行動的人士的實物或電子簽名.']
['請填寫您的投訴內容.']
['請發送電子郵件給我們,']
Pathophysiology of breast cancer refers to the abnormal changes in the normal physiological processes and mechanisms that occur in the development and progression of breast cancer.
It involves the study of the underlying biological and molecular mechanisms that lead to the uncontrolled growth and spread of cancer cells in the breast tissue.
This includes the genetic, epigenetic, and environmental factors that contribute to the initiation, promotion, and progression of breast cancer.
Some of the key pathophysiological changes in breast cancer include:
1. Genetic mutations: Mutations in certain genes, such as BRCA1 and BRCA2, can increase the risk of developing breast cancer.
These mutations can be inherited or acquired during a person's lifetime.
2. Hormonal imbalances: Hormones, particularly estrogen, can play a role in the development and growth of breast cancer.
An imbalance in hormone levels or exposure to excess estrogen can increase the risk of breast cancer.
3. Inflammation: Chronic inflammation in the breast tissue can contribute to the development of breast cancer by promoting the growth and survival of cancer cells.
4. Tumor microenvironment: The environment surrounding the tumor, including the extracellular matrix, immune cells, and blood vessels, can influence the growth and spread of breast cancer.
5. Metastasis: Breast cancer can spread to other parts of the body through the lymphatic system or bloodstream, leading to the formation of secondary tumors in distant organs.
Understanding the pathophysiology of breast cancer is crucial for developing effective prevention, early detection, and treatment strategies.
This web site is provided for educational and informational purposes only and does not constitute providing medical advice or professional services.
The information provided should not be used for diagnosing or treating a health problem or disease, and those seeking personal medical advice should consult with a licensed physician.
Please note the neural net that generates answers to the questions, is specially inaccurate when it comes to numeric content. For example, the number of people diagnosed with a specific disease.
Always seek the advice of your doctor or other qualified health provider regarding a medical condition. Never disregard professional medical advice or delay in seeking it because of something you have read on this website. If you think you may have a medical emergency, call 911 or go to the nearest emergency room immediately. No physician-patient relationship is created by this web site or its use. Neither BioMedLib nor its employees, nor any contributor to this web site, makes any representations, express or implied, with respect to the information provided herein or to its use.
The Digital Millennium Copyright Act of 1998, 17 U.S.C. § 512 (the “DMCA”) provides recourse for copyright owners who believe that material appearing on the Internet infringes their rights under U.S. copyright law. If you believe in good faith that any content or material made available in connection with our website or services infringes your copyright, you (or your agent) may send us a notice requesting that the content or material be removed, or access to it blocked. Notices must be sent in writing by email (see 'Contact' section for email address) . The DMCA requires that your notice of alleged copyright infringement include the following information: (1) description of the copyrighted work that is the subject of claimed infringement; (2) description of the alleged infringing content and information sufficient to permit us to locate the content; (3) contact information for you, including your address, telephone number and email address; (4) a statement by you that you have a good faith belief that the content in the manner complained of is not authorized by the copyright owner, or its agent, or by the operation of any law; (5) a statement by you, signed under penalty of perjury, that the information in the notification is accurate and that you have the authority to enforce the copyrights that are claimed to be infringed; and (6) a physical or electronic signature of the copyright owner or a person authorized to act on the copyright owner’s behalf. Failure to include all of the above information may result in the delay of the processing of your complaint.
['生物醫學圖書館使用自動化計算機 (機器學習算法) 來生成問答對.']
['開始於3500萬份的生物醫學出版物.']
['請見"參考資料"以及"聲明".']