How to treat Urticaria?

Lalela leli khasi

Ungayelapha kanjani i-urticaria?

I - urticaria, evame ukubizwa ngokuthi i - hives, iyisimo sesikhumba esiboniswa ama - itchy, raised welts angavela kunoma iyiphi ingxenye yomzimba.

Kungase kubangelwe izici ezihlukahlukene, kuhlanganise nokusabela kokungezwani komzimba, ukutheleleka, noma izimo zempilo eziyisisekelo.

Ukwelashwa kwe-urticaria kuncike ezingeni elibucayi lesimo kanye nembangela yaso.

Nazi ezinye izindlela zokwelapha ezivamile:

1. Ama-antihistamine: Le mithi isiza ekunciphiseni ukulunywa nokuvuvukala ngokuvimbela imiphumela ye-histamine, ikhemikhali ekhishwa umzimba ngesikhathi sokungezwani komzimba.

Ama-antihistamine angathengiswa ngaphandle komtholampilo anjenge-diphenhydramine (Benadryl) noma i-loratadine (Claritin) angasebenza ezimweni ezilula.

Ezimweni ezinzima kakhulu, udokotela angase anikeze ama-antihistamine anamandla.

2. Ama-corticosteroid: Ezimweni lapho ama-antihistamine engasebenzi khona, ama-corticosteroid anjenge-prednisone angabekwa ukuze anciphise ukuvuvukala futhi acindezele amasosha omzimba.

Le mithi ivame ukuthathwa ngomlomo futhi inganikeza impumuzo esheshayo.

3. Ama-immunosuppressant: Ezimweni ze-urticaria engapheli ezingaphenduli kwezinye izindlela zokwelapha, izidakamizwa ezicindezela amasosha omzimba ezifana ne-cyclosporine noma i-methotrexate zingabekwa ukuze kuvinjelwe amasosha omzimba futhi kuncishiswe ukuvuvukala.

I-Omalizumab: Lo muthi uwumuthi wokugoma we-monoclonal ongenziwa ngomjovo ohlose futhi uvimbele i-immunoglobulin E (IgE), iprotheni ehilelekile ekusebenzeni kwe-allergic.

Ngokuvamile isetshenziselwa i-urticaria engapheli engasabeli kwezinye izindlela zokwelapha.

5. Gwema izinto ezibangela i-urticaria: Ukukhomba nokugwema izinto ezibangela i-urticaria kungasiza ekuvimbeleni ukuqubuka.

Izimbangela ezivamile zihlanganisa ukudla okuthile, imithi, ukulunywa izinambuzane, nokuchayeka ekushiseni, emakhazeni noma ekukhanyeni kwelanga.

6. Ukucindezela okubandayo: Ukusebenzisa ukucindezela okubandayo endaweni ethintekile kungasiza ekunciphiseni ukulunywa nokuvuvukala.

7. Izindwangu ezimanzi: Izindwangu ezimanzi zingasetshenziselwa ukudambisa ukulunywa nokunciphisa ukuvuvukala.

Indwangu enomswakama ifakwa endaweni ethintekile, bese kufakwa indwangu eyomile phezu kwayo ukuze igcine umswakama.

8. Ukwelashwa ngokukhanya: Ukuchayeka ekukhanyeni kwe-ultraviolet kungasiza ekucindezeleni amasosha omzimba futhi kunciphise ukuvuvukala kwezinye izimo ze-urticaria engapheli.

Kubalulekile ukuba uthintane nochwepheshe wezokunakekelwa kwempilo ukuze uthole ukuxilongwa nokwelashwa okufanele kwe-urticaria.

Bangasiza ekunqumeni imbangela eyinhloko futhi bancome uhlelo lokwelashwa olufaneleke kakhulu.

Izikhombo

PubMed/Medline https://www.nlm.nih.gov/databases/download/pubmed_medline.html

RefinedWeb https://arxiv.org/abs/2306.01116

Deleanu D, Nedelea I, Petricau C, Leru P, Dumitrascu D, Muntean A: Clinical impact of omalizumab in refractory chronic urticaria: One centre experience. Exp Ther Med. 2019, 18 (6): 5078-5081.

Grundmann SA, Kiefer S, Luger TA, Brehler R: Delayed pressure urticaria - dapsone heading for first-line therapy? J Dtsch Dermatol Ges. 2011, 9 (11): 908-12.

Staumont-Sallé D, Piette F, Delaporte E: [Etiological diagnosis and treatment of chronic urticaria]. Rev Med Interne. 2003, 24 (1): 34-44.

Akashi R, Ishiguro N, Shimizu S, Kawashima M: Clinical study of the relationship between Helicobacter pylori and chronic urticaria and prurigo chronica multiformis: effectiveness of eradication therapy for Helicobacter pylori. J Dermatol. 2011, 38 (8): 761-6.

Calogiuri G, Nettis E, Mandurino-Mirizzi A, Di Leo E, Macchia L, Foti C, Vacca A, Kounis NG: Omalizumab for the Treatment of Persistent Drug Induced Urticaria Elicited by Thienopyridines: A Case Report. Antiinflamm Antiallergy Agents Med Chem. 2020, 19 (3): 335-339.

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How to treat urticaria?

Urticaria, commonly known as hives, is a skin condition characterized by itchy, raised welts that can appear on any part of the body.

It can be caused by various factors, including allergic reactions, infections, or underlying medical conditions.

Treatment for urticaria depends on the severity of the condition and the underlying cause.

Here are some common treatment options:

1. Antihistamines: These medications help to reduce itching and swelling by blocking the effects of histamine, a chemical released by the body during an allergic reaction.

Over-the-counter antihistamines such as diphenhydramine (Benadryl) or loratadine (Claritin) can be effective in mild cases.

In more severe cases, a doctor may prescribe stronger antihistamines.

2. Corticosteroids: In cases where antihistamines are not effective, corticosteroids such as prednisone may be prescribed to reduce inflammation and suppress the immune system.

These medications are usually taken orally and can provide quick relief.

3. Immunosuppressants: In cases of chronic urticaria that do not respond to other treatments, immunosuppressant drugs such as cyclosporine or methotrexate may be prescribed to suppress the immune system and reduce inflammation.

4. Omalizumab: This medication is an injectable monoclonal antibody that targets and blocks immunoglobulin E (IgE), a protein involved in allergic reactions.

It is typically used for chronic urticaria that does not respond to other treatments.

5. Avoid triggers: Identifying and avoiding triggers that cause urticaria can help prevent outbreaks.

Common triggers include certain foods, medications, insect bites, and exposure to heat, cold, or sunlight.

6. Cold compress: Applying a cold compress to the affected area can help reduce itching and swelling.

7. Wet wraps: Wet wraps can be used to soothe itching and reduce inflammation.

A damp cloth is wrapped around the affected area, and then a dry cloth is placed over it to retain moisture.

8. Phototherapy: Exposure to ultraviolet light can help suppress the immune system and reduce inflammation in some cases of chronic urticaria.

It is important to consult a healthcare professional for proper diagnosis and treatment of urticaria.

They can help determine the underlying cause and recommend the most appropriate treatment plan.

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